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DK1996923T3 - Fremgangsmåder til adskillelse af isomerer ved hjælp af massespektrometri - Google Patents

Fremgangsmåder til adskillelse af isomerer ved hjælp af massespektrometri

Info

Publication number
DK1996923T3
DK1996923T3 DK07752007.0T DK07752007T DK1996923T3 DK 1996923 T3 DK1996923 T3 DK 1996923T3 DK 07752007 T DK07752007 T DK 07752007T DK 1996923 T3 DK1996923 T3 DK 1996923T3
Authority
DK
Denmark
Prior art keywords
methods
mass spectrometry
separating isomers
isomers
separating
Prior art date
Application number
DK07752007.0T
Other languages
English (en)
Inventor
Blas Cerda
Original Assignee
Perkinelmer Health Sci Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Perkinelmer Health Sci Inc filed Critical Perkinelmer Health Sci Inc
Application granted granted Critical
Publication of DK1996923T3 publication Critical patent/DK1996923T3/da

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6806Determination of free amino acids
    • G01N33/6812Assays for specific amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/36Gynecology or obstetrics
    • G01N2800/368Pregnancy complicated by disease or abnormalities of pregnancy, e.g. preeclampsia, preterm labour

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Obesity (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Vascular Medicine (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
DK07752007.0T 2006-03-02 2007-03-02 Fremgangsmåder til adskillelse af isomerer ved hjælp af massespektrometri DK1996923T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US77848306P 2006-03-02 2006-03-02
PCT/US2007/005279 WO2007103124A2 (en) 2006-03-02 2007-03-02 Methods for distinguishing isomers using mass spectrometry

Publications (1)

Publication Number Publication Date
DK1996923T3 true DK1996923T3 (da) 2012-10-01

Family

ID=38475391

Family Applications (1)

Application Number Title Priority Date Filing Date
DK07752007.0T DK1996923T3 (da) 2006-03-02 2007-03-02 Fremgangsmåder til adskillelse af isomerer ved hjælp af massespektrometri

Country Status (10)

Country Link
US (1) US20080073500A1 (da)
EP (1) EP1996923B1 (da)
JP (1) JP2009528544A (da)
CN (1) CN101438148B (da)
AU (1) AU2007224240B2 (da)
BR (1) BRPI0708485A2 (da)
CA (1) CA2644499A1 (da)
DK (1) DK1996923T3 (da)
ES (1) ES2392629T3 (da)
WO (1) WO2007103124A2 (da)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102005056408B4 (de) * 2005-05-28 2007-05-31 Esa Patentverwertungsagentur Sachsen-Anhalt Gmbh Verfahren zur Bestimmung der Konzentration von asymmetrischem Dimethylarginin (ADMA)
WO2009043149A1 (en) * 2007-10-01 2009-04-09 Mds Analytical Technologies, A Business Unit Of Mds Inc., Doing Business Through Its Sciex Division Analysis of conjugated metabolites of alcohol consumption
AU2010224175A1 (en) 2009-03-10 2011-09-29 Duke University Predicting coronary artery disease and risk of cardiovascular events
AU2015258285B2 (en) * 2009-03-10 2017-09-07 Duke University Predicting coronary artery disease and risk of cardiovascular events
WO2010108180A2 (en) * 2009-03-20 2010-09-23 The Cleveland Clinic Foundation Citrulline, a risk indicator for cardiovascular disease
CA2762364A1 (en) * 2009-05-27 2010-12-02 Dh Technologies Development Pte. Ltd. Linear ion trap for msms
CN102458481A (zh) * 2009-05-28 2012-05-16 克里夫兰诊所基金会 用于诊断和预测疾病的含三甲胺的化合物
JP2012529015A (ja) * 2009-06-02 2012-11-15 バイオクラテス ライフ サイエンシーズ アーゲー 腎臓疾患評価用新規バイオマーカー
US20120164663A1 (en) * 2009-06-15 2012-06-28 The Cleveland Clinic Foundation Methylated Arginine Metabolites as Risk Predictors of Cardiovascular Disease
EP3422006B1 (en) * 2009-12-21 2023-11-01 University College Cork, National University of Ireland, Cork Detection of risk of pre-eclampsia
HUE039900T2 (hu) * 2010-03-22 2019-02-28 Stemina Biomarker Discovery Inc Gyógyszerek humán fejlõdésre gyakorolt toxicitásának elõrejelzése humán õssejtszerû sejtek és metabolomika alkalmazásával
EP2659501B1 (en) * 2010-12-28 2017-09-06 Quest Diagnostics Investments Incorporated Quantitation of insulin by mass spectrometry
CN102154444B (zh) * 2010-12-30 2013-09-25 北京九强生物技术股份有限公司 测定不对称二甲基精氨酸浓度的方法及诊断试剂盒
US20120318971A1 (en) * 2011-06-16 2012-12-20 Baylor Research Institute Analysis of total homocysteine and methylmalonic acid in plasma by lc-ms/ms from a plasma separator device (psd)
EP3663758A1 (en) * 2012-03-18 2020-06-10 Shiseido Company, Ltd. Apparatus, system and method for analyzing disease sample
CN103207173B (zh) * 2013-03-13 2015-06-17 北大工学院绍兴技术研究院 一种酶学检测方法
US9659759B2 (en) 2013-09-25 2017-05-23 Council Of Scientific And Industrial Research Quantitation of structural isomers using MALDI MS/MS
CA2951762A1 (en) * 2014-06-13 2015-12-17 Dh Technologies Development Pte. Ltd. Methods for analysis of lipids using mass spectrometry
ES2936294T3 (es) * 2015-02-20 2023-03-15 Idexx Lab Inc Inmunoensayo homogéneo con compensación para señal de fondo
US10451641B2 (en) 2015-03-13 2019-10-22 Duke University Compositions and methods for metabolic profiling in subjects with heart failure with preserved ejection fraction
CN104849298B (zh) * 2015-05-26 2017-10-31 衢州普林千叶电子科技有限公司 一种用于核磁分析的样品检测分析仪和方法
CN105628623B (zh) * 2015-12-25 2018-08-24 北京市农林科学院 一种鉴别光学异构化合物旋光性的方法
CN107764891B (zh) * 2017-10-16 2020-03-13 杭州先导医药科技有限责任公司 一种恩替卡韦手性异构体的区分测定方法
US10854438B2 (en) * 2018-03-19 2020-12-01 Agilent Technologies, Inc. Inductively coupled plasma mass spectrometry (ICP-MS) with improved signal-to-noise and signal-to-background ratios
WO2020090887A1 (ja) * 2018-11-02 2020-05-07 国立大学法人神戸大学 分析方法、吸着防止剤および分析用キット
CA3211118A1 (en) * 2021-02-19 2022-08-25 Idexx Laboratories, Inc. Mass spectrometric analysis of biomarkers

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3055142B2 (ja) * 1989-11-24 2000-06-26 株式会社島津製作所 質量分析方法
JP2000111526A (ja) * 1998-09-30 2000-04-21 Hitachi Ltd 質量分析計
CA2516182A1 (en) * 2003-02-28 2004-09-16 Bayer Pharmaceuticals Corporation Expression profiles for breast cancer and methods of use
GB0308967D0 (en) * 2003-04-17 2003-05-28 Univ London Screen for pre-eclampsia
DE102005056408B4 (de) * 2005-05-28 2007-05-31 Esa Patentverwertungsagentur Sachsen-Anhalt Gmbh Verfahren zur Bestimmung der Konzentration von asymmetrischem Dimethylarginin (ADMA)

Also Published As

Publication number Publication date
WO2007103124A3 (en) 2008-10-09
JP2009528544A (ja) 2009-08-06
CA2644499A1 (en) 2007-09-13
US20080073500A1 (en) 2008-03-27
EP1996923B1 (en) 2012-06-27
EP1996923A4 (en) 2010-04-07
BRPI0708485A2 (pt) 2011-05-31
AU2007224240A1 (en) 2007-09-13
CN101438148A (zh) 2009-05-20
ES2392629T3 (es) 2012-12-12
CN101438148B (zh) 2014-01-22
EP1996923A2 (en) 2008-12-03
WO2007103124A2 (en) 2007-09-13
AU2007224240B2 (en) 2013-07-25

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