DK2350128T3 - Fremgangsmåder til fremstilling af antistoffer fra plasmaceller - Google Patents

Fremgangsmåder til fremstilling af antistoffer fra plasmaceller

Info

Publication number: DK2350128T3
Authority: DK; Denmark
Prior art keywords: methods; plasma cells; producing antibodies; antibodies; producing
Prior art date: 2008-10-22

Application number

DK09804310.2T

Other languages

English (en)

Inventor

Antonio Lanzavecchia

David Jarrossay

Original Assignee

Inst Research In Biomedicine

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-10-22

Filing date

2009-10-22

Publication date

2014-12-01

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41796120&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK2350128(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2008-10-22 Priority claimed from GB0819376A external-priority patent/GB0819376D0/en

2009-07-27 Priority claimed from US12/509,731 external-priority patent/US9340603B2/en

2009-10-22 Application filed by Inst Research In Biomedicine filed Critical Inst Research In Biomedicine

2014-12-01 Application granted granted Critical

2014-12-01 Publication of DK2350128T3 publication Critical patent/DK2350128T3/da

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1018—Orthomyxoviridae, e.g. influenza virus
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1267—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
- C07K16/1282—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Clostridium (G)
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0635—B lymphocytes
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
- C12N2502/1394—Bone marrow stromal cells; whole marrow

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Immunology (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Medicinal Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Biochemistry (AREA)
Biomedical Technology (AREA)
Biophysics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Zoology (AREA)
Biotechnology (AREA)
Wood Science & Technology (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Virology (AREA)
Microbiology (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
General Engineering & Computer Science (AREA)
Hematology (AREA)
Cell Biology (AREA)
Communicable Diseases (AREA)
Pulmonology (AREA)
Oncology (AREA)
Transplantation (AREA)
Mycology (AREA)
Epidemiology (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Peptides Or Proteins (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

DK09804310.2T 2008-10-22 2009-10-22 Fremgangsmåder til fremstilling af antistoffer fra plasmaceller DK2350128T3 (da)

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
GB0819376A GB0819376D0 (en)	2008-10-22	2008-10-22	Method for culturing human plasma cells
US18158209P	2009-05-27	2009-05-27
US12/509,731 US9340603B2 (en)	2008-07-25	2009-07-27	Neutralizing anti-influenza A virus antibodies and uses thereof
PCT/IB2009/006616 WO2010010466A2 (en)	2008-07-25	2009-07-27	Neutralizing anti-influenza a virus antibodies and uses thereof
PCT/IB2009/007375 WO2010046775A2 (en)	2008-10-22	2009-10-22	Methods for producing antibodies from plasma cells

Publications (1)

Publication Number	Publication Date
DK2350128T3 true DK2350128T3 (da)	2014-12-01

Family

ID=41796120

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK09804310.2T DK2350128T3 (da)	2008-10-22	2009-10-22	Fremgangsmåder til fremstilling af antistoffer fra plasmaceller

Country Status (18)

Country	Link
US (1)	US9347043B2 (da)
EP (2)	EP2350128B1 (da)
JP (1)	JP5837820B2 (da)
KR (1)	KR101606608B1 (da)
CN (1)	CN102282170B (da)
AU (1)	AU2009306010B2 (da)
BR (1)	BRPI0914092B1 (da)
CA (1)	CA2740138C (da)
CL (1)	CL2011000797A1 (da)
DK (1)	DK2350128T3 (da)
EA (1)	EA024586B1 (da)
ES (1)	ES2525346T3 (da)
IL (1)	IL212121A (da)
MX (1)	MX2011003855A (da)
NZ (1)	NZ592036A (da)
PL (1)	PL2350128T3 (da)
WO (1)	WO2010046775A2 (da)
ZA (1)	ZA201102387B (da)

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EP2400298B1 (en) *	2010-05-28	2013-08-14	F.Hoffmann-La Roche Ag	Single B-cell cultivation method and specific antibody production
US10087408B2 (en)	2010-07-07	2018-10-02	The University Of British Columbia	System and method for microfluidic cell culture
US20130115606A1 (en)	2010-07-07	2013-05-09	The University Of British Columbia	System and method for microfluidic cell culture
US9188593B2 (en)	2010-07-16	2015-11-17	The University Of British Columbia	Methods for assaying cellular binding interactions
US9487583B2 (en) *	2011-03-30	2016-11-08	National University Corporation University Of Toyama	Method for selecting plasma cells or plasmablasts, method for producing target antigen specific antibodies, and novel monoclonal antibodies
EP3418300B1 (en)	2011-07-18	2020-10-28	Institute for Research in Biomedicine	Neutralizing anti-influenza a virus antibodies and uses thereof
NZ630920A (en)	2012-03-20	2017-01-27	Humabs Biomed Sa	Antibodies that neutralize rsv, mpv and pvm and uses thereof
US9969794B2 (en)	2012-05-10	2018-05-15	Visterra, Inc.	HA binding agents
WO2016075546A2 (en)	2014-11-14	2016-05-19	Antonio Lanzavecchia	Antibodies that neutralize ebola virus and uses thereof
EP3220947B1 (en)	2014-11-18	2020-10-28	Humabs Biomed S.A.	Antibodies that potently neutralize rabies virus and other lyssaviruses and uses thereof
EP3313871A1 (en)	2015-06-26	2018-05-02	Institute for Research in Biomedicine	Proteins comprising a mutated lair-1 fragment and uses thereof
WO2017059878A1 (en)	2015-10-07	2017-04-13	Humabs Biomed Sa	Antibodies that potently neutralize hepatitis b virus and uses thereof
WO2017083627A1 (en)	2015-11-13	2017-05-18	Visterra, Inc.	Compositions and methods for treating and preventing influenza
WO2017147248A1 (en)	2016-02-24	2017-08-31	Visterra, Inc.	Formulations of antibody molecules to influenza virus
CN105950552A (zh) *	2016-05-26	2016-09-21	宁波艾科生物科技有限公司	一种分泌抗原特异性抗体浆细胞的分离方法
WO2018010789A1 (en)	2016-07-13	2018-01-18	Humabs Biomed Sa	Novel antibodies specifically binding to zika virus epitopes and uses thereof
IL269904B2 (en)	2017-04-19	2025-10-01	Inst Res Biomedicine	Plasmodium sporozoite NPDP peptides as a vaccine and target for novel malaria vaccines and antibody binding
WO2019024979A1 (en)	2017-07-31	2019-02-07	Institute For Research In Biomedicine	FUNCTIONAL DOMAIN ANTIBODIES IN THE ELBOW REGION
JP6622825B2 (ja) *	2018-01-25	2019-12-18	インスティテュート・フォー・リサーチ・イン・バイオメディシンＩｎｓｔｉｔｕｔｅＦｏｒＲｅｓｅａｒｃｈＩｎＢｉｏｍｅｄｉｃｉｎｅ	Ａ型インフルエンザウイルス中和抗体及びその使用法
US12304946B2 (en)	2018-12-19	2025-05-20	Humabs Biomed Sa	Antibodies that neutralize hepatitis B virus and uses thereof
CN113924147A (zh)	2019-03-25	2022-01-11	威特拉公司	用于治疗和预防流感的组合物和方法
WO2020221451A1 (en)	2019-04-30	2020-11-05	Humabs Biomed Sa	Antibodies binding to plasmodium circumsporozoite protein and uses thereof
WO2020221450A1 (en)	2019-04-30	2020-11-05	Humabs Biomed Sa	Antibodies and methods for treatment of influenza a infection
EP3757127A1 (en)	2019-06-28	2020-12-30	Institute for Research in Biomedicine	Deimmunized antibodies binding to alpha-4 integrin and uses thereof
IL290752B1 (en)	2019-08-29	2025-10-01	Vir Biotechnology Inc	Preparations and methods for treating influenza A infection
NZ785788A (en)	2019-08-29	2025-09-26	Vir Biotechnology Inc	Antibody compositions and methods for treating hepatitis b virus infection
JP2020048568A (ja) *	2019-11-22	2020-04-02	インスティテュート・フォー・リサーチ・イン・バイオメディシンＩｎｓｔｉｔｕｔｅＦｏｒＲｅｓｅａｒｃｈＩｎＢｉｏｍｅｄｉｃｉｎｅ	Ａ型インフルエンザウイルス中和抗体及びその使用法
AR122722A1 (es)	2020-06-24	2022-09-28	Vir Biotechnology Inc	Anticuerpos que neutralizan el virus de la hepatitis b y sus usos
US20240034772A1 (en)	2020-12-08	2024-02-01	Humabs Biomed Sa	Antibodies binding to f-protein of metapneumovirus and uses thereof
CN116917315A (zh)	2020-12-08	2023-10-20	维尔生物科技有限公司	用于治疗甲型流感感染的抗体和方法
WO2022161598A1 (en)	2021-01-26	2022-08-04	Eth Zurich	Antibodies broadly targeting coronaviruses and uses thereof
WO2022161597A1 (en)	2021-01-26	2022-08-04	Eth Zurich	Method for rapid identification of cross-reactive and/or rare antibodies
US20240092872A1 (en)	2021-01-26	2024-03-21	Vir Biotechnology, Inc.	Compositions and methods for treating hepatitis b virus infection
WO2022162009A1 (en)	2021-01-26	2022-08-04	Eth Zurich	Method for rapid identification of cross-reactive and/or rare antibodies
WO2022162012A2 (en)	2021-01-26	2022-08-04	Eth Zurich	Antibodies broadly targeting coronaviruses and uses thereof
US20250129142A1 (en)	2021-09-07	2025-04-24	Institute For Research In Biomedicine	Antibodies binding to tetanus toxin and uses thereof
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2009
- 2009-10-22 ES ES09804310.2T patent/ES2525346T3/es active Active
- 2009-10-22 CN CN200980142313.8A patent/CN102282170B/zh active Active
- 2009-10-22 US US12/604,240 patent/US9347043B2/en active Active
- 2009-10-22 EA EA201100668A patent/EA024586B1/ru active IP Right Revival
- 2009-10-22 EP EP09804310.2A patent/EP2350128B1/en active Active
- 2009-10-22 MX MX2011003855A patent/MX2011003855A/es active IP Right Grant
- 2009-10-22 WO PCT/IB2009/007375 patent/WO2010046775A2/en not_active Ceased
- 2009-10-22 AU AU2009306010A patent/AU2009306010B2/en not_active Ceased
- 2009-10-22 NZ NZ592036A patent/NZ592036A/xx not_active IP Right Cessation
- 2009-10-22 PL PL09804310T patent/PL2350128T3/pl unknown
- 2009-10-22 KR KR1020117008167A patent/KR101606608B1/ko active Active
- 2009-10-22 CA CA2740138A patent/CA2740138C/en active Active
- 2009-10-22 EP EP14003359.8A patent/EP2848630A1/en not_active Withdrawn
- 2009-10-22 DK DK09804310.2T patent/DK2350128T3/da active
- 2009-10-22 JP JP2011532738A patent/JP5837820B2/ja active Active
- 2009-10-22 BR BRPI0914092-1A patent/BRPI0914092B1/pt not_active IP Right Cessation
2011
- 2011-03-31 ZA ZA2011/02387A patent/ZA201102387B/en unknown
- 2011-04-04 IL IL212121A patent/IL212121A/en active IP Right Grant
- 2011-04-11 CL CL2011000797A patent/CL2011000797A1/es unknown

Also Published As

Publication number	Publication date
AU2009306010B2 (en)	2015-12-24
AU2009306010A1 (en)	2010-04-29
EP2848630A1 (en)	2015-03-18
PL2350128T3 (pl)	2015-03-31
EA024586B1 (ru)	2016-10-31
ES2525346T3 (es)	2014-12-22
KR20110073506A (ko)	2011-06-29
KR101606608B1 (ko)	2016-03-25
CA2740138C (en)	2017-01-10
MX2011003855A (es)	2011-12-16
CN102282170B (zh)	2015-04-08
WO2010046775A3 (en)	2010-06-17
US9347043B2 (en)	2016-05-24
IL212121A0 (en)	2011-06-30
CL2011000797A1 (es)	2012-03-16
CN102282170A (zh)	2011-12-14
ZA201102387B (en)	2012-09-26
EP2350128B1 (en)	2014-10-01
US20100145031A1 (en)	2010-06-10
WO2010046775A2 (en)	2010-04-29
BRPI0914092B1 (pt)	2021-08-31
HK1164899A1 (en)	2012-09-28
CA2740138A1 (en)	2010-04-29
JP2012506251A (ja)	2012-03-15
NZ592036A (en)	2012-12-21
BRPI0914092A2 (pt)	2015-10-27
JP5837820B2 (ja)	2015-12-24
EA201100668A1 (ru)	2012-06-29
EP2350128A2 (en)	2011-08-03
IL212121A (en)	2016-03-31

Publication	Publication Date	Title
DK2350128T3 (da)	2014-12-01	Fremgangsmåder til fremstilling af antistoffer fra plasmaceller
DK2554160T3 (da)	2015-04-27	Fremgangsmåde til fremstilling af en beriget IgG-sammensætning fra plasma
DK2291488T3 (da)	2019-09-30	Fremgangsmåde til forbehandling af biomasse
IL200919A0 (en)	2011-07-31	Methods for generation of antibodies
DK2451839T3 (da)	2020-07-13	Fremgangsmåde til produktion af variable domæner
DK2334639T3 (da)	2013-05-06	Fremgangsmåder til fremstilling af aminosulfonforbindelser
DK3330370T3 (da)	2021-05-10	Fremgangsmåde til dyrkning af cho-celler
DK2580156T4 (da)	2020-09-07	Fremgangsmåde til lagring af hydrogen
DK3730045T3 (da)	2022-04-04	Fremgangsmåde til indføring af en analytsensor
DK2531526T3 (da)	2017-11-13	Fremgangsmåde til opnåelse af antistoffer
EP2277993A4 (en)	2011-11-09	PROCESS FOR PRODUCING ENDOTHELIAL CELLS (AND VARIANTS)
DK2358661T3 (da)	2014-06-30	Fremgangsmåde til fremstilling af trans-4-amino-cyclohexyl-eddikesyreethylester-hcl
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