DK1732929T3 - Tricyklisk benzopyranforbindelse som anti-arytmika - Google Patents
Tricyklisk benzopyranforbindelse som anti-arytmikaInfo
- Publication number
- DK1732929T3 DK1732929T3 DK05727581.0T DK05727581T DK1732929T3 DK 1732929 T3 DK1732929 T3 DK 1732929T3 DK 05727581 T DK05727581 T DK 05727581T DK 1732929 T3 DK1732929 T3 DK 1732929T3
- Authority
- DK
- Denmark
- Prior art keywords
- group
- hydrogen atom
- ring
- atom
- bond
- Prior art date
Links
- 239000003416 antiarrhythmic agent Substances 0.000 title abstract 2
- 230000003288 anthiarrhythmic effect Effects 0.000 title 1
- -1 benzopyran compound Chemical class 0.000 title 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 5
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 3
- 125000005915 C6-C14 aryl group Chemical group 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 229910052717 sulfur Inorganic materials 0.000 abstract 2
- 125000004890 (C1-C6) alkylamino group Chemical group 0.000 abstract 1
- 125000006553 (C3-C8) cycloalkenyl group Chemical group 0.000 abstract 1
- 125000006552 (C3-C8) cycloalkyl group Chemical group 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 125000004429 atom Chemical group 0.000 abstract 1
- 150000001562 benzopyrans Chemical class 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000000470 constituent Substances 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000004434 sulfur atom Chemical group 0.000 abstract 1
- 125000002813 thiocarbonyl group Chemical group *C(*)=S 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D515/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D515/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D515/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyrane Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Plural Heterocyclic Compounds (AREA)
- Dental Preparations (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2004084605 | 2004-03-23 | ||
| PCT/JP2005/006004 WO2005090357A1 (en) | 2004-03-23 | 2005-03-23 | Tricyclic benzopyran compound as anti-arrhythmic agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1732929T3 true DK1732929T3 (da) | 2010-12-20 |
Family
ID=34962589
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK05727581.0T DK1732929T3 (da) | 2004-03-23 | 2005-03-23 | Tricyklisk benzopyranforbindelse som anti-arytmika |
Country Status (30)
| Country | Link |
|---|---|
| US (2) | US7652008B2 (da) |
| EP (1) | EP1732929B1 (da) |
| JP (1) | JP4840594B2 (da) |
| KR (2) | KR101019402B1 (da) |
| CN (3) | CN1934116B (da) |
| AT (1) | ATE485299T1 (da) |
| AU (2) | AU2005223612B2 (da) |
| BR (1) | BRPI0508768A (da) |
| CA (1) | CA2558139C (da) |
| CY (1) | CY1111250T1 (da) |
| CZ (1) | CZ2006598A3 (da) |
| DE (1) | DE602005024245D1 (da) |
| DK (1) | DK1732929T3 (da) |
| EG (1) | EG27163A (da) |
| ES (1) | ES2353021T3 (da) |
| HR (1) | HRP20110005T1 (da) |
| IL (1) | IL177950A (da) |
| MX (1) | MXPA06010880A (da) |
| NO (1) | NO339495B1 (da) |
| NZ (2) | NZ549570A (da) |
| PL (1) | PL1732929T3 (da) |
| PT (1) | PT1732929E (da) |
| RS (1) | RS51742B (da) |
| RU (1) | RU2380370C2 (da) |
| SI (1) | SI1732929T1 (da) |
| SK (1) | SK287994B6 (da) |
| TW (1) | TWI352704B (da) |
| UA (1) | UA91189C2 (da) |
| WO (1) | WO2005090357A1 (da) |
| ZA (1) | ZA200607388B (da) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101019402B1 (ko) * | 2004-03-23 | 2011-03-07 | 닛산 가가쿠 고교 가부시키 가이샤 | 항부정맥제로 사용되는 삼환계 벤조피란 화합물 |
| JP5126540B2 (ja) | 2006-03-10 | 2013-01-23 | 日産化学工業株式会社 | 光学活性クロメンオキシド化合物の製造方法 |
| WO2010018867A1 (ja) * | 2008-08-14 | 2010-02-18 | 日産化学工業株式会社 | ジ置換ベンゾピラン化合物 |
| KR101703202B1 (ko) * | 2009-04-30 | 2017-02-06 | 닛산 가가쿠 고교 가부시키 가이샤 | 3환성 벤조피란 화합물의 신규한 결정형태 및 그 제조방법 |
| SMT201700430T1 (it) | 2009-06-25 | 2018-01-11 | Alkermes Pharma Ireland Ltd | Composti eterociclici per il trattamento di disturbi neurologici e psicologici |
| US9464095B2 (en) | 2012-09-27 | 2016-10-11 | Nissan Chemical Industries, Ltd. | Production method of high-purity nitrogen-containing heterocyclic compound |
| CN104507948B (zh) * | 2012-09-27 | 2017-05-03 | 日产化学工业株式会社 | 含氮杂环n‑氧化物化合物的制造方法 |
| CN105377826A (zh) * | 2013-07-25 | 2016-03-02 | 日产化学工业株式会社 | 杂环化合物的制造方法 |
| KR102009756B1 (ko) * | 2017-01-06 | 2019-08-12 | 고려대학교 세종산학협력단 | 신규한 퀴놀리논 유도체 및 이를 유효성분으로 포함하는 천식 또는 아토피 등의 알러지성 질환의 예방 또는 치료용 약학 조성물 |
| US11273158B2 (en) | 2018-03-05 | 2022-03-15 | Alkermes Pharma Ireland Limited | Aripiprazole dosing strategy |
| CN108727261B (zh) * | 2018-06-21 | 2021-09-24 | 济南大学 | 一种硝基取代喹那啶的制备方法 |
| TWI844607B (zh) * | 2018-12-28 | 2024-06-11 | 國立大學法人大阪大學 | 遺傳性徐脈性心律不整治療藥 |
| RU2754610C1 (ru) * | 2020-04-14 | 2021-09-03 | Георгий Викторович ТЕЦ | Препарат для лечения заболеваний, вызванных бактериями |
| JP7733887B2 (ja) * | 2020-06-26 | 2025-09-04 | 国立大学法人大阪大学 | 薬剤誘発性徐脈および徐脈性不整脈治療薬 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZM7682A1 (en) | 1981-09-25 | 1983-05-23 | Beecham Group Plc | Active compounds |
| JPS5867683U (ja) | 1981-10-28 | 1983-05-09 | 株式会社ナムコ | 歩行ロボツト |
| JPH0699439B2 (ja) * | 1988-02-03 | 1994-12-07 | 日産化学工業株式会社 | ピラノベンゾオキサジアゾール誘導体 |
| JP2658198B2 (ja) * | 1988-06-23 | 1997-09-30 | 日産化学工業株式会社 | ピラノベンゾトリアゾール誘導体 |
| JP2876712B2 (ja) * | 1989-07-17 | 1999-03-31 | 日産化学工業株式会社 | 光学活性ピラノベンゾオキサジアゾール誘導体 |
| US5097037A (en) | 1989-07-17 | 1992-03-17 | Nissan Chemical Industries, Ltd. | Process for the optical resolution of pyranobenzoxadiazole compounds |
| US5164509A (en) * | 1990-11-26 | 1992-11-17 | E. R. Squibb & Sons, Inc. | Benzodiazolo analogs |
| SK117195A3 (en) * | 1993-04-02 | 1997-04-09 | Nissan Chemical Ind Ltd | Heart failure remedy |
| JPH07300414A (ja) * | 1993-04-02 | 1995-11-14 | Nissan Chem Ind Ltd | 心不全治療薬 |
| JP2734457B2 (ja) | 1994-02-23 | 1998-03-30 | 日産化学工業株式会社 | 不斉エポキシ化反応 |
| JPH10501256A (ja) * | 1994-06-10 | 1998-02-03 | スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー | Ｃ−４アミド置換化合物およびその治療剤としての使用 |
| HRP970255B1 (en) * | 1996-05-15 | 2003-10-31 | Hoechst Ag | Sulfonamido substituted chromane derivatives, method for their preparation, their use as medicaments or diagnostic agents as well as medicaments containing them |
| AU3959099A (en) | 1998-06-03 | 1999-12-20 | Nissan Chemical Industries Ltd. | Indan derivatives |
| AU5444499A (en) | 1998-09-01 | 2000-03-21 | Nissan Chemical Industries Ltd. | Benzoxazine derivatives |
| WO2000058300A1 (en) | 1999-03-25 | 2000-10-05 | Nissan Chemical Industries, Ltd. | Chroman derivatives |
| AU766935B2 (en) * | 1999-09-17 | 2003-10-23 | Nissan Chemical Industries Ltd. | Benzopyran derivative |
| EP1214307B1 (en) | 1999-09-24 | 2004-04-07 | Nissan Chemical Industries, Ltd. | 4-oxybenzopyran derivative |
| AU7453900A (en) | 1999-10-05 | 2001-05-10 | Nissan Chemical Industries Ltd. | 4-oxybenzopyran derivative |
| TW589305B (en) | 2001-02-14 | 2004-06-01 | Nissan Chemical Ind Ltd | 4-aminobenzopyran derivatives |
| RU2291867C2 (ru) | 2001-06-25 | 2007-01-20 | Ниссан Кемикал Индастриз, Лтд. | Замещенные производные бензопирана против аритмии |
| WO2003014113A1 (en) | 2001-08-06 | 2003-02-20 | Glenmark Pharmaceuticals Limited | Novel benzopyran compounds and process for their preparation and use |
| KR101019402B1 (ko) * | 2004-03-23 | 2011-03-07 | 닛산 가가쿠 고교 가부시키 가이샤 | 항부정맥제로 사용되는 삼환계 벤조피란 화합물 |
-
2005
- 2005-03-23 KR KR1020067021988A patent/KR101019402B1/ko not_active Expired - Lifetime
- 2005-03-23 AT AT05727581T patent/ATE485299T1/de active
- 2005-03-23 BR BRPI0508768-6A patent/BRPI0508768A/pt not_active Application Discontinuation
- 2005-03-23 DK DK05727581.0T patent/DK1732929T3/da active
- 2005-03-23 NZ NZ549570A patent/NZ549570A/en not_active IP Right Cessation
- 2005-03-23 CN CN2005800090295A patent/CN1934116B/zh not_active Expired - Lifetime
- 2005-03-23 MX MXPA06010880A patent/MXPA06010880A/es active IP Right Grant
- 2005-03-23 WO PCT/JP2005/006004 patent/WO2005090357A1/en not_active Ceased
- 2005-03-23 SK SK5079-2006A patent/SK287994B6/sk not_active IP Right Cessation
- 2005-03-23 KR KR1020107027058A patent/KR101085979B1/ko not_active Expired - Fee Related
- 2005-03-23 AU AU2005223612A patent/AU2005223612B2/en not_active Ceased
- 2005-03-23 CN CN2011100751168A patent/CN102190661B/zh not_active Expired - Fee Related
- 2005-03-23 RU RU2006137284/04A patent/RU2380370C2/ru not_active IP Right Cessation
- 2005-03-23 HR HR20110005T patent/HRP20110005T1/hr unknown
- 2005-03-23 CA CA2558139A patent/CA2558139C/en not_active Expired - Fee Related
- 2005-03-23 DE DE602005024245T patent/DE602005024245D1/de not_active Expired - Lifetime
- 2005-03-23 PL PL05727581T patent/PL1732929T3/pl unknown
- 2005-03-23 JP JP2006530022A patent/JP4840594B2/ja not_active Expired - Lifetime
- 2005-03-23 US US10/590,975 patent/US7652008B2/en active Active
- 2005-03-23 PT PT05727581T patent/PT1732929E/pt unknown
- 2005-03-23 NZ NZ585606A patent/NZ585606A/en not_active IP Right Cessation
- 2005-03-23 CZ CZ20060598A patent/CZ2006598A3/cs unknown
- 2005-03-23 CN CN2008101707921A patent/CN101429200B/zh not_active Expired - Fee Related
- 2005-03-23 RS RS20110028A patent/RS51742B/sr unknown
- 2005-03-23 ES ES05727581T patent/ES2353021T3/es not_active Expired - Lifetime
- 2005-03-23 UA UAA200611101A patent/UA91189C2/ru unknown
- 2005-03-23 EP EP05727581A patent/EP1732929B1/en not_active Expired - Lifetime
- 2005-03-23 ZA ZA200607388A patent/ZA200607388B/en unknown
- 2005-03-23 SI SI200531171T patent/SI1732929T1/sl unknown
- 2005-03-23 TW TW094108962A patent/TWI352704B/zh not_active IP Right Cessation
-
2006
- 2006-09-02 EG EGNA2006000900 patent/EG27163A/xx active
- 2006-09-07 IL IL177950A patent/IL177950A/en not_active IP Right Cessation
- 2006-10-23 NO NO20064819A patent/NO339495B1/no not_active IP Right Cessation
-
2009
- 2009-11-17 US US12/591,353 patent/US7964623B2/en not_active Expired - Fee Related
-
2010
- 2010-07-08 AU AU2010202900A patent/AU2010202900B2/en not_active Ceased
-
2011
- 2011-01-19 CY CY20111100060T patent/CY1111250T1/el unknown
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