HRP970255B1 - Sulfonamido substituted chromane derivatives, method for their preparation, their use as medicaments or diagnostic agents as well as medicaments containing them - Google Patents

Sulfonamido substituted chromane derivatives, method for their preparation, their use as medicaments or diagnostic agents as well as medicaments containing them

Info

Publication number: HRP970255B1
Authority: HR; Croatia
Prior art keywords: medicaments; preparation; well; diagnostic agents; chromane derivatives
Prior art date: 1996-05-15

Application number

HR970255A

Inventor

Hans-Jochen Lang

Uwe Gerlach

Joachim Brendel

Heinrich Christian Englert

Heinz Goegelein

Max Hropot

Helmut Bohn

Andreas Herling

Andreas Busch

Rainer Greger

Original Assignee

Hoechst Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-05-15

Filing date

1997-05-13

Publication date

2003-10-31

1996-05-15 Priority claimed from DE19619614A external-priority patent/DE19619614A1/en

1996-09-26 Priority claimed from DE1996139462 external-priority patent/DE19639462A1/en

1997-05-13 Application filed by Hoechst Ag filed Critical Hoechst Ag

1998-04-30 Publication of HRP970255A2 publication Critical patent/HRP970255A2/en

2003-10-31 Publication of HRP970255B1 publication Critical patent/HRP970255B1/en

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C07D311/68—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with nitrogen atoms directly attached in position 4
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C07D311/70—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyrane Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Saccharide Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

HR970255A 1996-05-15 1997-05-13 Sulfonamido substituted chromane derivatives, method for their preparation, their use as medicaments or diagnostic agents as well as medicaments containing them HRP970255B1 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE19619614A DE19619614A1 (en)	1996-05-15	1996-05-15	New sulphonamide derivatives of chroman
DE1996139462 DE19639462A1 (en)	1996-09-26	1996-09-26	New sulphonamide derivatives of chroman

Publications (2)

Publication Number	Publication Date
HRP970255A2 HRP970255A2 (en)	1998-04-30
HRP970255B1 true HRP970255B1 (en)	2003-10-31

Family

ID=26025736

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HR970255A HRP970255B1 (en)	1996-05-15	1997-05-13	Sulfonamido substituted chromane derivatives, method for their preparation, their use as medicaments or diagnostic agents as well as medicaments containing them

Country Status (23)

Country	Link
EP (1)	EP0807629B1 (en)
JP (1)	JP4234798B2 (en)
KR (1)	KR100547921B1 (en)
CN (1)	CN1204134C (en)
AR (2)	AR007115A1 (en)
AT (1)	ATE260909T1 (en)
AU (1)	AU711986B2 (en)
BR (1)	BR9703161A (en)
CA (1)	CA2205477A1 (en)
CZ (1)	CZ149497A3 (en)
DE (1)	DE59711352D1 (en)
DK (1)	DK0807629T3 (en)
ES (1)	ES2218617T3 (en)
HR (1)	HRP970255B1 (en)
HU (1)	HUP9700903A3 (en)
IL (1)	IL120827A (en)
NO (1)	NO315556B1 (en)
NZ (1)	NZ314800A (en)
PL (1)	PL191330B1 (en)
PT (1)	PT807629E (en)
SK (1)	SK283837B6 (en)
TR (1)	TR199700369A2 (en)
TW (1)	TW496866B (en)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NZ329200A (en) *	1996-12-16	1999-05-28	Hoechst Ag	Sulphonamide substituted quinazoline, isoquinoline, quinoline or benzo[1,3-]oxazine derivatives and medicaments
DE19705133A1 (en) *	1997-02-11	1998-08-13	Hoechst Ag	Sulfonamide-substituted compounds, processes for their preparation, their use as medicaments or diagnostic agents and medicaments containing them
DE19706675A1 (en) *	1997-02-20	1998-08-27	Hoechst Ag	Sulfonamide-substituted chromanes, processes for their preparation, their use as medicaments or diagnostic agents and medicaments containing them
EP0895994A3 (en)	1997-08-05	1999-12-15	Hoechst Marion Roussel Deutschland GmbH	Sulphonamide-substituted Pyranopyridines, process for their production and their use as a drug or diagnostics as well as medicaments containing them
DE19742508A1 (en) *	1997-09-26	1999-04-01	Hoechst Marion Roussel De Gmbh	Sulfonamide-substituted chromanes, processes for their preparation, their use as medicaments or diagnostic agents and pharmaceutical preparations containing them
DE19742509A1 (en) *	1997-09-26	1999-04-01	Hoechst Marion Roussel De Gmbh	Sulfonamide-substituted chromanes, processes for their preparation, their use as medicaments or diagnostic agents and pharmaceutical preparations containing them
DE19748469A1 (en) *	1997-11-03	1999-05-06	Hoechst Marion Roussel De Gmbh	Sulfonamide-substituted benzopyran derivatives, processes for their preparation, their use as medicaments and pharmaceutical preparations containing them
EP1109544A4 (en)	1998-09-01	2004-10-27	Bristol Myers Squibb Co	Potassium channel inhibitors and method
DE19858253A1 (en) *	1998-12-17	2000-06-21	Aventis Pharma Gmbh	Use of KQt1 channel inhibitors for the manufacture of a medicament for the treatment of diseases caused by helminths and ectoparasites
US7368582B2 (en)	2003-10-17	2008-05-06	Solvay Pharmaceuticals Gmbh	Amidomethyl-substituted 2-(4-sulfonylamino)-3-hydroxy-3,4-dihydro-2H-chromen-6-yl compounds, a process and intermediates for their production, and pharmaceutical compositions containing them
US7652008B2 (en) *	2004-03-23	2010-01-26	Nissan Chemical Industries, Ltd.	Tricyclic benzopyran compound as anti-arrhythmic agents
US7884109B2 (en)	2005-04-05	2011-02-08	Wyeth Llc	Purine and imidazopyridine derivatives for immunosuppression
US7989459B2 (en)	2006-02-17	2011-08-02	Pharmacopeia, Llc	Purinones and 1H-imidazopyridinones as PKC-theta inhibitors
CL2007002867A1 (en)	2006-10-04	2008-06-27	Pharmacopeia Inc	COMPOUNDS DERIVED FROM 2- (BENCIMIDAZOLIL) PURINA, INHIBITORS OF JANUS QUINASA 3; PHARMACEUTICAL COMPOSITION THAT CONTAINS THEM; AND ITS USE TO TREAT AUTOIMMUNE, INFLAMMATORY, CARDIOVASCULAR DISEASES, IMPLANT REJECTION, AMONG OTHERS.
WO2008043031A1 (en)	2006-10-04	2008-04-10	Pharmacopeia, Inc.	6-substituted 2-(benzimidazolyl)purine and purinone derivatives for immunosuppression
US7902187B2 (en)	2006-10-04	2011-03-08	Wyeth Llc	6-substituted 2-(benzimidazolyl)purine and purinone derivatives for immunosuppression
UA105385C2 (en) *	2009-04-30	2014-05-12	Ниссан Кэмикал Индастриз, Лтд.	Normal;heading 1;heading 2;heading 3;CRYSTAL FORM OF TRICYCLIC BENZOPYRAN COMPOUND AND PRODUCTION METHOD THEREOF
TWI583677B (en) *	2012-09-21	2017-05-21	日本臟器製藥股份有限公司	Coumarin derivative
CN103012380B (en) *	2013-01-10	2015-03-04	山东大学	Chroman compound, and preparation method and application thereof
JP6089055B2 (en) *	2014-03-20	2017-03-01	日本臓器製薬株式会社	Pharmaceuticals containing coumarin derivatives
AR117169A1 (en)	2018-11-28	2021-07-14	Bayer Ag	(TIO) PYRIDAZINE AMIDES AS FUNGICIDE COMPOUNDS
WO2021224220A1 (en)	2020-05-06	2021-11-11	Bayer Aktiengesellschaft	Pyridine (thio)amides as fungicidal compounds
CN115605462A (en)	2020-05-12	2023-01-13	拜耳公司（De）	Triazines and pyrimidine(thio)amides as fungicidal compounds
BR112022023550A2 (en)	2020-05-19	2023-01-03	Bayer Cropscience Ag	AZABICYCLIC (THIO)AMIDES AS FUNGICIDAL COMPOUNDS
JP7760531B2 (en)	2020-05-27	2025-10-27	バイエル、アクチエンゲゼルシャフト	Active compound combinations
JP2024540323A (en)	2021-11-03	2024-10-31	バイエル、アクチエンゲゼルシャフト	Bis(hetero)aryl thioether (thio)amides as fungicidal compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3737195A1 (en) *	1987-11-03	1989-05-18	Bayer Ag	CHROME DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE IN MEDICINAL PRODUCTS
FR2639349B1 (en) *	1988-11-23	1991-02-22	Sanofi Sa	NOVEL CHROMANE DERIVATIVES ACTIVE IN THE CENTRAL NERVOUS SYSTEM, THEIR PREPARATION METHOD AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME
US5104890A (en) *	1989-03-28	1992-04-14	Fujisawa Pharmaceutical Company, Ltd.	Benzopyran derivatives and processes for preparation thereof

1997
- 1997-05-13 NZ NZ314800A patent/NZ314800A/en unknown
- 1997-05-13 ES ES97107775T patent/ES2218617T3/en not_active Expired - Lifetime
- 1997-05-13 AR ARP970101998A patent/AR007115A1/en not_active Application Discontinuation
- 1997-05-13 TR TR97/00369A patent/TR199700369A2/en unknown
- 1997-05-13 AT AT97107775T patent/ATE260909T1/en not_active IP Right Cessation
- 1997-05-13 HR HR970255A patent/HRP970255B1/en not_active IP Right Cessation
- 1997-05-13 SK SK603-97A patent/SK283837B6/en unknown
- 1997-05-13 AU AU20806/97A patent/AU711986B2/en not_active Ceased
- 1997-05-13 TW TW086106326A patent/TW496866B/en not_active IP Right Cessation
- 1997-05-13 EP EP97107775A patent/EP0807629B1/en not_active Expired - Lifetime
- 1997-05-13 DE DE59711352T patent/DE59711352D1/en not_active Expired - Lifetime
- 1997-05-13 DK DK97107775T patent/DK0807629T3/en active
- 1997-05-13 CN CNB971115400A patent/CN1204134C/en not_active Expired - Fee Related
- 1997-05-13 PT PT97107775T patent/PT807629E/en unknown
- 1997-05-14 JP JP13798497A patent/JP4234798B2/en not_active Expired - Fee Related
- 1997-05-14 BR BR9703161A patent/BR9703161A/en not_active Application Discontinuation
- 1997-05-14 CZ CZ971494A patent/CZ149497A3/en unknown
- 1997-05-14 NO NO19972211A patent/NO315556B1/en unknown
- 1997-05-14 IL IL12082797A patent/IL120827A/en not_active IP Right Cessation
- 1997-05-15 PL PL319995A patent/PL191330B1/en unknown
- 1997-05-15 CA CA002205477A patent/CA2205477A1/en not_active Abandoned
- 1997-05-15 KR KR1019970018635A patent/KR100547921B1/en not_active Expired - Fee Related
- 1997-05-15 HU HU9700903A patent/HUP9700903A3/en unknown
- 1997-11-26 AR ARP970105574A patent/AR010314A1/en unknown

Also Published As

Publication number	Publication date
TW496866B (en)	2002-08-01
DK0807629T3 (en)	2004-05-17
DE59711352D1 (en)	2004-04-08
HK1006640A1 (en)	1999-03-12
JPH1067772A (en)	1998-03-10
TR199700369A2 (en)	1997-12-21
BR9703161A (en)	1998-09-29
AR010314A1 (en)	2000-06-07
MX9703534A (en)	1997-11-29
SK60397A3 (en)	1998-02-04
KR100547921B1 (en)	2006-10-19
JP4234798B2 (en)	2009-03-04
ATE260909T1 (en)	2004-03-15
CA2205477A1 (en)	1997-11-15
NZ314800A (en)	1999-02-25
NO972211L (en)	1997-11-17
AU2080697A (en)	1997-11-20
IL120827A (en)	2004-12-15
NO315556B1 (en)	2003-09-22
HRP970255A2 (en)	1998-04-30
PL191330B1 (en)	2006-04-28
CN1204134C (en)	2005-06-01
IL120827A0 (en)	1997-09-30
HU9700903D0 (en)	1997-07-28
AU711986B2 (en)	1999-10-28
KR19980024020A (en)	1998-07-06
ES2218617T3 (en)	2004-11-16
CN1169429A (en)	1998-01-07
AR007115A1 (en)	1999-10-13
SK283837B6 (en)	2004-03-02
PT807629E (en)	2004-07-30
HUP9700903A2 (en)	1998-12-28
CZ149497A3 (en)	1997-12-17
HUP9700903A3 (en)	1999-03-01
NO972211D0 (en)	1997-05-14
EP0807629B1 (en)	2004-03-03
PL319995A1 (en)	1997-11-24
EP0807629A1 (en)	1997-11-19

Publication	Publication Date	Title
HRP970255A2 (en)	1998-04-30	Sulfonamido substituted chromane derivatives, method for their preparation, their use as medicaments or diagnostic agents as well as medicaments containing them
HUP0000658A3 (en)	2001-03-28	Sulphonamide derivatives, process for their preparation, and their use as medicaments
SI0771788T1 (en)	2000-04-30	Substituted sulphonimidamides, method for their preparation, their use as medicament or diagnostic and medicament containing them
HU9603038D0 (en)	1997-01-28	Novel erythromycin derivatives, method for their preparation and their use as drugs
HUP0100684A3 (en)	2002-06-28	Substituted chroman derivatives, process for their preparation and medicaments containing them
HUP9701270A3 (en)	2002-08-28	Neuraminic acid derivatives, medicaments containing them and their use for producing medicaments
HUP0100276A3 (en)	2002-08-28	Substituted chroman derivatives, process for their preparation and medicaments containing them
HUP9901326A3 (en)	2000-12-28	Benzopyran derivatives having leukotriene-antagonistic action, pharmaceutical compositions containing these compounds, process for the preparation and use of these compounds and compositions
HUP0104033A3 (en)	2002-08-28	1-benzoyl-tetrahydropyridazine derivatives, process for their preparation, their use and medicaments containing the compounds
FI952117A7 (en)	1995-11-06	Substituted bicyclic heteroaroylguanidines, a method for their preparation, their use as a pharmaceutical or diagnostic agent, and a pharmaceutical containing them
HRP970292A2 (en)	1998-04-30	Substituted 2-naphtoylguanidines, process for their preparation, their use as medicament or diagnostic agent and medicament containing them
HRP960041B1 (en)	2000-08-31	Basically substituted benzoylguanidines, process for their preparation, their use as medicaments or diagnostics as well as medicaments containing them
FI953173A7 (en)	1995-12-30	Ortho-amino-substituted benzolylguanidines, a method for their preparation, their use as a medicinal substance or diagnostic substance, and a medicinal substance containing them
HUP0104819A3 (en)	2003-01-28	Chroman derivatives, their use intermediate and process for their preparation
CY2220B1 (en)	2003-04-18	Substituted benzenesulfonylureas and -thioureas process for their preparation their use as medicament or diagnostic agent as well as medicaments containing them
AU5539798A (en)	1998-08-27	Sulfonamide-substituted chromans, processes for their preparation, their use as medicament or diagnostic aid, and medicament comprising them
HUP9600665A2 (en)	1997-10-28	Substituted benzothienylpiperazines, their use as medicaments, and processes for their preparation
HRP970424B1 (en)	2002-06-30	Substituted indanylidineacetylguanidines, process for their preparation, their use as medicaments or diagnostic agents and medicaments containing them
PL346165A1 (en)	2002-01-28	Biphenylsulfonyl-substituted imidazole derivatives, their preparation process, their use as a drug or diagnostic agent and drug containing them
HU9403134D0 (en)	1995-01-30	Substituted pyridylsalicylaldehyde-and salicyklicacid derivatives, process for their preparation und their use as herbicide
HUP0001180A3 (en)	2003-05-28	Novel erythromycin derivatives, method for preparing them and their use as medicine
HUP9802156A3 (en)	2001-05-28	Sulfonamide-substituted chromanes, method for producing them, their use as medicine, medicaments containing them
HRP970081B1 (en)	2003-04-30	Substituted thiophenylalkenylcarbonylguanidides, method for their preparation, their use as medicinal or diagnostic agent as well as medicament containing them
AU2371397A (en)	1997-12-04	Substituted 1-naphthoylguanidines, process for their preparation, their use as medicament or diagnostic, and medicament containing them
SI0807629T1 (en)	2004-06-30	Sulfonamido substituted chromane derivatives, method for their preparation, their use as medicaments or diagnostic agents aswell as medicaments containing them

Legal Events

Date	Code	Title	Description
1998-04-30	A1OB	Publication of a patent application
1998-10-28	AIPI	Request for the grant of a patent on the basis of a substantive examination of a patent application
2003-10-31	B1PR	Patent granted
2005-05-03	ODRP	Renewal fee for the maintenance of a patent	Payment date: 20050503 Year of fee payment: 9
2006-11-14	PBON	Lapse due to non-payment of renewal fee	Effective date: 20060514