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DK1705989T3 - Substituerede arylpyrazoler som parasiticide midler - Google Patents

Substituerede arylpyrazoler som parasiticide midler

Info

Publication number
DK1705989T3
DK1705989T3 DK04801410T DK04801410T DK1705989T3 DK 1705989 T3 DK1705989 T3 DK 1705989T3 DK 04801410 T DK04801410 T DK 04801410T DK 04801410 T DK04801410 T DK 04801410T DK 1705989 T3 DK1705989 T3 DK 1705989T3
Authority
DK
Denmark
Prior art keywords
parasitic agents
substituted arylpyrazoles
arylpyrazoles
substituted
parasitic
Prior art date
Application number
DK04801410T
Other languages
English (en)
Inventor
Denis Billen
Nathan Anthony Logan Chubb
David Morris Gethin
Kim Thomas Hall
Lee Richard Roberts
Nigel Derek Arthur Walshe
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of DK1705989T3 publication Critical patent/DK1705989T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/08Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
    • A01N47/28Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N<
    • A01N47/38Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N< containing the group >N—CO—N< where at least one nitrogen atom is part of a heterocyclic ring; Thio analogues thereof
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/561,2-Diazoles; Hydrogenated 1,2-diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4151,2-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4151,2-Diazoles
    • A61K31/4161,2-Diazoles condensed with carbocyclic ring systems, e.g. indazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/14Ectoparasiticides, e.g. scabicides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/38Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/38Nitrogen atoms
    • C07D231/40Acylated on said nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Environmental Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
DK04801410T 2003-12-18 2004-12-15 Substituerede arylpyrazoler som parasiticide midler DK1705989T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0329314.9A GB0329314D0 (en) 2003-12-18 2003-12-18 Substituted arylpyrazoles
PCT/IB2004/004193 WO2005060749A1 (en) 2003-12-18 2004-12-15 Substituted arylpyrazoles as parasiticidal agents

Publications (1)

Publication Number Publication Date
DK1705989T3 true DK1705989T3 (da) 2009-01-19

Family

ID=30471290

Family Applications (1)

Application Number Title Priority Date Filing Date
DK04801410T DK1705989T3 (da) 2003-12-18 2004-12-15 Substituerede arylpyrazoler som parasiticide midler

Country Status (32)

Country Link
US (1) US7435753B2 (da)
EP (1) EP1705989B8 (da)
JP (2) JP4805164B2 (da)
KR (1) KR100815637B1 (da)
CN (1) CN100377645C (da)
AR (1) AR046942A1 (da)
AT (1) ATE413809T1 (da)
AU (1) AU2004304717B2 (da)
BR (1) BRPI0417810B8 (da)
CA (1) CA2549479C (da)
CY (1) CY1108649T1 (da)
DE (1) DE602004017782D1 (da)
DK (1) DK1705989T3 (da)
EA (1) EA010740B1 (da)
ES (1) ES2315724T3 (da)
GB (1) GB0329314D0 (da)
IL (1) IL175992A0 (da)
IS (1) IS8492A (da)
MA (1) MA28269A1 (da)
MX (1) MXPA06007006A (da)
NO (1) NO20062549L (da)
NZ (1) NZ547565A (da)
PL (1) PL1705989T3 (da)
PT (1) PT1705989E (da)
RS (1) RS51111B (da)
SI (1) SI1705989T1 (da)
TN (1) TNSN06187A1 (da)
TW (1) TW200526605A (da)
UA (1) UA83397C2 (da)
UY (1) UY28670A1 (da)
WO (1) WO2005060749A1 (da)
ZA (1) ZA200604715B (da)

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US7514464B2 (en) * 2003-12-18 2009-04-07 Pfizer Limited Substituted arylpyrazoles
US20080146643A1 (en) * 2005-06-15 2008-06-19 Pfizer Limited Combination
US20070149464A1 (en) * 2005-06-15 2007-06-28 Pfizer Inc. Combination
ES2338699T3 (es) * 2005-06-15 2010-05-11 Pfizer Limited Arilpirazoles sustituidos para uso contra parasitos.
US20080176865A1 (en) * 2005-06-15 2008-07-24 Pfizer Limited Substituted arylpyrazoles
US7645786B2 (en) * 2005-06-15 2010-01-12 Pfizer Inc. Substituted arylpyrazoles
EP1968578A4 (en) 2005-12-14 2011-02-23 Makhteshim Chem Works Ltd POLYMORPHIC AND AMORPHOUS FORMS OF 5-AMINO-L- [2,6-DICHLORO-4- (TRIFLUOROMETHYL) PHENYL] -4- [(TRIFLUOROMETHYL) SULFINYL] -IH-PYRAZOLE-3-CARBONITRIL
FR2928919B1 (fr) * 2008-03-19 2011-07-29 Rhodia Operations Procede de preparation de l'acide difluoroacetique et de ses sels
MX2011001601A (es) 2008-08-14 2011-03-29 Bayer Cropscience Ag 4-fenil-1h-pirazoles insecticidas.
EP2184273A1 (de) 2008-11-05 2010-05-12 Bayer CropScience AG Halogen-substituierte Verbindungen als Pestizide
CN102356070B (zh) * 2009-03-16 2014-07-16 巴斯夫欧洲公司 制备吡唑衍生物的方法
EP2253617A1 (de) 2009-05-20 2010-11-24 Bayer CropScience AG Halogen-substituierte Verbindungen als Pestizide
US20110129574A1 (en) * 2009-11-30 2011-06-02 Pathak Chandrashekhar P Methods and compositions for filling fleshy fruits and vegetables
CN102933563A (zh) 2010-04-08 2013-02-13 Ah美国42有限责任公司 作为杀虫剂和杀螨剂的取代的3,5-二苯基异噁唑啉衍生物
JP2012046486A (ja) * 2010-07-30 2012-03-08 Sumitomo Chemical Co Ltd 動物外部寄生虫防除剤
CA2807005C (en) 2010-08-05 2015-04-07 Ah Usa 42 Llc Isoxazoline derivatives as antiparasitic agents
BR112013006686A2 (pt) 2010-09-24 2017-11-14 Zoetis Llc isoxazolina oximas como agentes antiparasitários
FR2972452B1 (fr) 2011-03-09 2013-03-15 Rhodia Operations Procede de preparation du difluoroacetonitrile et de ses derives
PT2683723T (pt) 2011-03-10 2016-08-05 Zoetis Services Llc Derivados espirocíclicos de isoxazolina como agentes antiparasitários
WO2012127347A1 (en) 2011-03-22 2012-09-27 Pfizer Inc. Isoxazoline derivatives as antiparasitic agents
CN104169273B (zh) 2012-02-03 2016-11-02 硕腾服务有限责任公司 作为抗寄生物剂的二氢呋喃氮杂环丁烷衍生物
JP6049866B2 (ja) 2012-05-09 2016-12-21 ゾエティス・サービシーズ・エルエルシー 駆虫剤としてのアゼチジン誘導体
MX363173B (es) 2012-12-12 2019-03-12 Zoetis Services Llc Composiciones inyectables de fenilpirazol.
DE102023117229A1 (de) 2023-06-29 2025-01-02 Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts Fluorcyclopropylierungsreagens

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US4479968A (en) 1980-10-17 1984-10-30 The Wellcome Foundation Ltd. Control of ectoparasitic infestations of pigs
US5232940A (en) * 1985-12-20 1993-08-03 Hatton Leslie R Derivatives of N-phenylpyrazoles
GB8531485D0 (en) 1985-12-20 1986-02-05 May & Baker Ltd Compositions of matter
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US5547974A (en) * 1985-12-20 1996-08-20 Rhone-Poulenc Agriculture Ltd. Derivatives of N-phenylpyrazoles
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ATE65013T1 (de) 1986-12-05 1991-07-15 Ciba Geigy Ag Ektoparasitizide nicht-waessrige pour-onfl¨ssigformulierung.
DE3706993A1 (de) 1987-03-05 1988-09-15 Bayer Ag 5-amino-3-halogenalkyl-1-aryl-pyrazole
SE455750B (sv) 1987-06-11 1988-08-01 Ericsson Telefon Ab L M Digitalt tidsmultiplext mobiltelefonisystem med ett effektivt utnyttjande av varje tidsram
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JPH08208620A (ja) * 1995-02-03 1996-08-13 Takeda Chem Ind Ltd アミノピラゾール誘導体、その製造法および用途
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GB9601128D0 (en) 1995-08-11 1996-03-20 Pfizer Ltd Parasiticidal compounds
JPH0987111A (ja) 1995-09-27 1997-03-31 Sumitomo Chem Co Ltd 害虫駆除用毒餌剤
FR2739255B1 (fr) 1995-09-29 1998-09-04 Rhone Merieux Composition antiparasitaire pour le traitement et la protection des animaux de compagnie
ES2191076T3 (es) 1995-12-19 2003-09-01 Bayer Cropscience Sa Nuevos derivados de 1-aril-pirazol y su empleo como plaguicidas.
IE970215A1 (en) 1996-03-29 1997-10-08 Rhone Merieux Direct pour-on skin solution for antiparasitic use in cattle¹and sheep
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GR1002899B (el) 1996-03-29 1998-05-11 Rhone Merieux Περιλαιμιο κατα ψυλλων και κροτωνων για σκυλους και γατες, με βαση ν-φαινυλπυραζολη
GR970100096A (el) 1996-03-29 1997-11-28 Merial Εξωτερικη διαταξη κατα των παρασιτων για βοοειδη με βαση τη ν-φαινυλπυραζολη, ειδικα σκουλαρικια.
TW524667B (en) * 1996-12-05 2003-03-21 Pfizer Parasiticidal pyrazoles
GB9801851D0 (en) * 1998-01-29 1998-03-25 Pfizer Ltd Parasiticidal agents
GB9810354D0 (en) 1998-05-14 1998-07-15 Pfizer Ltd Heterocycles

Also Published As

Publication number Publication date
IS8492A (is) 2006-05-31
ATE413809T1 (de) 2008-11-15
CN100377645C (zh) 2008-04-02
IL175992A0 (en) 2006-10-05
ZA200604715B (en) 2007-03-28
EP1705989B1 (en) 2008-11-12
PL1705989T3 (pl) 2009-04-30
CY1108649T1 (el) 2014-04-09
EA010740B1 (ru) 2008-10-30
JP2008174563A (ja) 2008-07-31
ES2315724T3 (es) 2009-04-01
US7435753B2 (en) 2008-10-14
NO20062549L (no) 2006-06-27
KR20060101777A (ko) 2006-09-26
PT1705989E (pt) 2009-01-20
AU2004304717B2 (en) 2010-11-18
DE602004017782D1 (de) 2008-12-24
TW200526605A (en) 2005-08-16
JP2007514735A (ja) 2007-06-07
JP4805164B2 (ja) 2011-11-02
CA2549479C (en) 2009-08-18
BRPI0417810A (pt) 2007-04-10
EA200600979A1 (ru) 2006-10-27
CN1893825A (zh) 2007-01-10
EP1705989A1 (en) 2006-10-04
BRPI0417810B1 (pt) 2018-11-21
WO2005060749A1 (en) 2005-07-07
AU2004304717A1 (en) 2005-07-07
NZ547565A (en) 2009-07-31
EP1705989B8 (en) 2009-03-25
AR046942A1 (es) 2006-01-04
UA83397C2 (uk) 2008-07-10
CA2549479A1 (en) 2005-07-07
US20050148649A1 (en) 2005-07-07
BRPI0417810B8 (pt) 2021-05-25
MXPA06007006A (es) 2006-08-31
SI1705989T1 (sl) 2009-02-28
KR100815637B1 (ko) 2008-03-20
GB0329314D0 (en) 2004-01-21
UY28670A1 (es) 2005-07-29
TNSN06187A1 (fr) 2007-11-15
MA28269A1 (fr) 2006-11-01
HK1096824A1 (en) 2007-06-15
RS51111B (sr) 2010-10-31

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