DK1656360T3 - Thiazolinderivater som selektive androgenreceptor-modulatorer - Google Patents
Thiazolinderivater som selektive androgenreceptor-modulatorerInfo
- Publication number
- DK1656360T3 DK1656360T3 DK04755044T DK04755044T DK1656360T3 DK 1656360 T3 DK1656360 T3 DK 1656360T3 DK 04755044 T DK04755044 T DK 04755044T DK 04755044 T DK04755044 T DK 04755044T DK 1656360 T3 DK1656360 T3 DK 1656360T3
- Authority
- DK
- Denmark
- Prior art keywords
- androgen receptor
- receptor modulators
- selective androgen
- thiazoline derivatives
- derivatives
- Prior art date
Links
- 150000003549 thiazolines Chemical class 0.000 title abstract 2
- 239000000849 selective androgen receptor modulator Substances 0.000 title 1
- 102000001307 androgen receptors Human genes 0.000 abstract 1
- 108010080146 androgen receptors Proteins 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/26—Androgens
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Dermatology (AREA)
- Reproductive Health (AREA)
- Virology (AREA)
- Pregnancy & Childbirth (AREA)
- Tropical Medicine & Parasitology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Urology & Nephrology (AREA)
- Gynecology & Obstetrics (AREA)
- Molecular Biology (AREA)
- AIDS & HIV (AREA)
- Nutrition Science (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US47871203P | 2003-06-13 | 2003-06-13 | |
| PCT/US2004/018665 WO2004113309A1 (en) | 2003-06-13 | 2004-06-12 | Thiazoline derivatives as selective androgen receptor modulators (sarms) |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1656360T3 true DK1656360T3 (da) | 2007-12-27 |
Family
ID=33539114
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK04755044T DK1656360T3 (da) | 2003-06-13 | 2004-06-12 | Thiazolinderivater som selektive androgenreceptor-modulatorer |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20050014952A1 (da) |
| EP (1) | EP1656360B1 (da) |
| JP (1) | JP4898446B2 (da) |
| CN (1) | CN1835937B (da) |
| AT (1) | ATE370133T1 (da) |
| AU (1) | AU2004249697B2 (da) |
| CA (1) | CA2528764A1 (da) |
| CY (1) | CY1106973T1 (da) |
| DE (1) | DE602004008300T2 (da) |
| DK (1) | DK1656360T3 (da) |
| ES (1) | ES2291906T3 (da) |
| PL (1) | PL1656360T3 (da) |
| PT (1) | PT1656360E (da) |
| WO (1) | WO2004113309A1 (da) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101103003A (zh) | 2004-11-16 | 2008-01-09 | 詹森药业有限公司 | 用作选择性雄激素受体调节剂(sarms)的新的杂环衍生物 |
| US7709516B2 (en) | 2005-06-17 | 2010-05-04 | Endorecherche, Inc. | Helix 12 directed non-steroidal antiandrogens |
| US9284345B2 (en) | 2007-04-12 | 2016-03-15 | Endorecherche, Inc. | 17alpha-substituted steroids as systemic antiandrogens and selective androgen receptor modulators |
| KR102438072B1 (ko) * | 2012-01-12 | 2022-08-31 | 예일 유니버시티 | E3 유비퀴틴 리가아제에 의한 표적 단백질 및 다른 폴리펩티드의 증진된 분해를 위한 화합물 및 방법 |
| CN103450112B (zh) * | 2013-08-07 | 2019-09-13 | 华东理工大学 | 一种n-桥连接的含氮五元杂环化合物及其制备与用途 |
| US9682960B2 (en) | 2013-12-19 | 2017-06-20 | Endorecherche, Inc. | Non-steroidal antiandrogens and selective androgen receptor modulators with a pyridyl moiety |
| US20190375732A1 (en) | 2018-05-14 | 2019-12-12 | David Hung | Anti-cancer nuclear hormone receptor-targeting compounds |
| CA3138197A1 (en) | 2019-05-14 | 2020-11-19 | Nuvation Bio Inc. | Anti-cancer nuclear hormone receptor-targeting compounds |
| WO2021097046A1 (en) | 2019-11-13 | 2021-05-20 | Nuvation Bio Inc. | Anti-cancer nuclear hormone receptor-targeting compounds |
| WO2022204184A1 (en) | 2021-03-23 | 2022-09-29 | Nuvation Bio Inc. | Anti-cancer nuclear hormone receptor-targeting compounds |
| WO2022235585A1 (en) | 2021-05-03 | 2022-11-10 | Nuvation Bio Inc. | Anti-cancer nuclear hormone receptor-targeting compounds |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX9602949A (es) * | 1994-01-24 | 1997-06-28 | Du Pont | 2-oxa y tia-zolinas artropodicidas. |
| US6403623B1 (en) * | 1999-05-27 | 2002-06-11 | Unuversity Of Notre Dame Du Lac | Heterocyclic antituberculosis agents |
| KR20030061783A (ko) * | 2000-08-24 | 2003-07-22 | 더 유니버시티 오브 테네시 리서치 코포레이션 | 선택적 안드로겐 수용체 조절제 및 이들의 사용 방법 |
-
2004
- 2004-06-12 CA CA002528764A patent/CA2528764A1/en not_active Abandoned
- 2004-06-12 AT AT04755044T patent/ATE370133T1/de active
- 2004-06-12 AU AU2004249697A patent/AU2004249697B2/en not_active Ceased
- 2004-06-12 JP JP2006533745A patent/JP4898446B2/ja not_active Expired - Fee Related
- 2004-06-12 DK DK04755044T patent/DK1656360T3/da active
- 2004-06-12 US US10/866,591 patent/US20050014952A1/en not_active Abandoned
- 2004-06-12 PT PT04755044T patent/PT1656360E/pt unknown
- 2004-06-12 ES ES04755044T patent/ES2291906T3/es not_active Expired - Lifetime
- 2004-06-12 WO PCT/US2004/018665 patent/WO2004113309A1/en not_active Ceased
- 2004-06-12 EP EP04755044A patent/EP1656360B1/en not_active Expired - Lifetime
- 2004-06-12 CN CN2004800230915A patent/CN1835937B/zh not_active Expired - Fee Related
- 2004-06-12 DE DE602004008300T patent/DE602004008300T2/de not_active Expired - Lifetime
- 2004-06-12 PL PL04755044T patent/PL1656360T3/pl unknown
-
2007
- 2007-11-05 CY CY20071101413T patent/CY1106973T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PL1656360T3 (pl) | 2008-01-31 |
| US20050014952A1 (en) | 2005-01-20 |
| WO2004113309A1 (en) | 2004-12-29 |
| CN1835937B (zh) | 2012-07-18 |
| JP4898446B2 (ja) | 2012-03-14 |
| EP1656360B1 (en) | 2007-08-15 |
| CA2528764A1 (en) | 2004-12-29 |
| AU2004249697A1 (en) | 2004-12-29 |
| DE602004008300T2 (de) | 2008-05-08 |
| DE602004008300D1 (de) | 2007-09-27 |
| JP2007501287A (ja) | 2007-01-25 |
| EP1656360A1 (en) | 2006-05-17 |
| ATE370133T1 (de) | 2007-09-15 |
| CY1106973T1 (el) | 2012-09-26 |
| AU2004249697B2 (en) | 2010-04-22 |
| ES2291906T3 (es) | 2008-03-01 |
| CN1835937A (zh) | 2006-09-20 |
| PT1656360E (pt) | 2007-10-22 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| TW200621725A (en) | Novel benzimidazole derivatives useful as selective androgen receptor modulators (sarms) | |
| SG10201809390QA (en) | Modulators of indoleamine 2,3-dioxygenase and methods of using the same | |
| WO2006031715A3 (en) | Novel imidazolidin-2-one derivatives as selective androgen receptor modulators (sarms) | |
| TW200621235A (en) | Novel heterocycle derivatives useful as selective androgen receptor modulators (sarms) | |
| EA200700489A1 (ru) | Новые бензоконденсированные гетероарилсульфамидные производные, полезные в качестве противоконвульсивных средств | |
| NO20083553L (no) | Indolsulfonamidmodulatorer av progrestonreseptorer | |
| CY1106973T1 (el) | Παραγωγα θειαζολινης ως εκλεκτικοι διαμορφωται υποδοχεως ανδρογονου (sarms) | |
| NO20070224L (no) | 2-karbamid-4-fenyltiazolderivater, fremstilling og terapeutisk anvendelse derav | |
| NO20076479L (no) | Nye oksadiazolderivater og anvendelse derav som positive allosteriske metabotropiske modulatorer av glutamatreseptorer | |
| TW200606146A (en) | Novel indole derivatives as selective androgen receptor modulators (SARMS) | |
| NO20082096L (no) | Azaindol-2-karboksamidderivativer | |
| ATE472529T1 (de) | Prolinamidderivate als natriumkanalmodulatoren | |
| CY1109569T1 (el) | Υποκατεστημενα παραγωγα κυκλοεξανο-1,4-διαμινης | |
| DK1989218T3 (da) | 17-phosphor-steroidderivater, der er anvendelige som progesteronreceptormodulatorer | |
| NO20082214L (no) | 1,1-Diokso-tiomorfolinyl-indolyl-metanonderivater for anvendelse som H3-modulatorer | |
| DK1937669T3 (da) | Nye benzopyranderivater som kaliumkanalåbnere | |
| TW200624424A (en) | Novel benzimidazole derivatives useful as selective androgen receptor modulators (sarms) | |
| NO20053810L (no) | Thiofenkarboksamider som inhibitorer av enzymet IKK-2 | |
| TW200604171A (en) | Novel indole derivatives as selective androgen receptor modulators (SARMs) | |
| TW200604170A (en) | Novel indole derivatives as selective androgen receptor modulators (SARMs) | |
| ATE473741T1 (de) | Neue imidazolopyrazolderivate als selektive androgen-rezeptor-modulatoren | |
| EA200601267A1 (ru) | Модуляторы рецепторов андрогена | |
| WO2003090672A3 (en) | 2-(quinolonyl)-fused heterocycles as androgen receptor modulators | |
| DK1994012T3 (da) | Nye tricykliske dihydropraziner som kaliumkanalåbnere |