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DK1525193T3 - Acylaminothiazolderivater, deres fremstilling og deres terapeutiske anvendelse - Google Patents

Acylaminothiazolderivater, deres fremstilling og deres terapeutiske anvendelse

Info

Publication number
DK1525193T3
DK1525193T3 DK03750801T DK03750801T DK1525193T3 DK 1525193 T3 DK1525193 T3 DK 1525193T3 DK 03750801 T DK03750801 T DK 03750801T DK 03750801 T DK03750801 T DK 03750801T DK 1525193 T3 DK1525193 T3 DK 1525193T3
Authority
DK
Denmark
Prior art keywords
preparation
therapeutic use
acylaminothiazole derivatives
acylaminothiazole
derivatives
Prior art date
Application number
DK03750801T
Other languages
English (en)
Inventor
Sylvie Baltzer
Bruno Schoentjes
Dorsselaer Viviane Van
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Application granted granted Critical
Publication of DK1525193T3 publication Critical patent/DK1525193T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
DK03750801T 2002-07-17 2003-07-11 Acylaminothiazolderivater, deres fremstilling og deres terapeutiske anvendelse DK1525193T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0209061A FR2842523A1 (fr) 2002-07-17 2002-07-17 Derives d'acylaminothiazole, leur preparation et leur application en therapeutique
PCT/FR2003/002194 WO2004009565A2 (fr) 2002-07-17 2003-07-11 Derives d'acylaminothiazole, leur utilisation comme inhibiteurs de beta-amyloi

Publications (1)

Publication Number Publication Date
DK1525193T3 true DK1525193T3 (da) 2008-04-28

Family

ID=29797510

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03750801T DK1525193T3 (da) 2002-07-17 2003-07-11 Acylaminothiazolderivater, deres fremstilling og deres terapeutiske anvendelse

Country Status (14)

Country Link
US (2) US7291636B2 (da)
EP (1) EP1525193B1 (da)
JP (1) JP4680593B2 (da)
AR (1) AR040570A1 (da)
AT (1) ATE382040T1 (da)
AU (1) AU2003269018A1 (da)
CY (1) CY1107903T1 (da)
DE (1) DE60318317T2 (da)
DK (1) DK1525193T3 (da)
ES (1) ES2297198T3 (da)
FR (1) FR2842523A1 (da)
PT (1) PT1525193E (da)
TW (1) TWI313680B (da)
WO (1) WO2004009565A2 (da)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2842523A1 (fr) * 2002-07-17 2004-01-23 Sanofi Synthelabo Derives d'acylaminothiazole, leur preparation et leur application en therapeutique
CA2501803A1 (en) * 2002-10-09 2004-04-22 Pfizer Products Inc. Thiazole compounds for the treatment of neurodegenerative disorders
PL1700856T3 (pl) * 2003-12-26 2016-05-31 Kyowa Hakko Kirin Co Ltd Pochodna tiazolu
FR2873370B1 (fr) * 2004-07-22 2006-10-20 Sanofi Synthelabo Derives d'acylaminothiazole, leur preparation et leur application en therapeutique
FR2865206B1 (fr) * 2004-01-16 2009-02-06 Sanofi Synthelabo Derives d'acylaminothiazole, leur preparation et leur application en therapeutique
SI1709018T1 (sl) 2004-01-16 2011-11-30 Sanofi Sa Acilaminotiazolni derivati in njihova uporaba kotbeta-amiloidni inhibitorji
AU2005209442B2 (en) * 2004-01-16 2011-03-31 Sanofi-Aventis Acylaminothiazole derivatives, preparation method thereof and use of same in therapeutics
US20050222227A1 (en) * 2004-04-01 2005-10-06 Pfizer Inc Oxazole-amine compounds for the treatment of neurodegenerative disorders
US7384968B2 (en) * 2004-04-01 2008-06-10 Pfizer Inc. Thiazole-amine compounds for the treatment of neurodegenerative disorders
ZA200700945B (en) * 2004-08-03 2008-09-25 Chiesi Farma Spa Derivatives of 1-phenylalkanecarboxylic acids for the treatment of neurodegenerative diseases
WO2007084391A2 (en) * 2006-01-18 2007-07-26 Amgen Inc. Thiazole compounds as protein kinase b ( pkb) inhibitors
WO2007116901A1 (ja) * 2006-04-05 2007-10-18 Banyu Pharmaceutical Co., Ltd. 新規アリールアミド誘導体
CN100415709C (zh) * 2006-05-15 2008-09-03 西北大学 β-(3,4-二羟基苯基)-α-羟基丙酸冰片酯、其合成方法和用途
DE102006048042A1 (de) * 2006-10-11 2008-04-17 Bayer Healthcare Ag Acylaminoimidazole und Acylaminothiazole
AU2008276512A1 (en) * 2007-07-17 2009-01-22 Amgen Inc. Thiadiazole modulators of PKB
US7897619B2 (en) 2007-07-17 2011-03-01 Amgen Inc. Heterocyclic modulators of PKB
WO2010044054A1 (en) * 2008-10-14 2010-04-22 Actelion Pharmaceuticals Ltd Phenethylamide derivatives and their heterocyclic analogues

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3796800A (en) * 1971-11-22 1974-03-12 Uniroyal Inc Anti-inflammatory triazole compositions and methods for using same
FR2546520B1 (fr) * 1983-05-27 1985-08-30 Sanofi Sa Nouveaux composes antibiotiques derives des cephalosporines
US5712270A (en) * 1995-11-06 1998-01-27 American Home Products Corporation 2-arylamidothiazole derivatives with CNS activity
ATE295346T1 (de) * 1996-11-22 2005-05-15 Elan Pharm Inc N-(aryl/heteroarylacetyl)aminosäureester, diese enthaltende pharmazeutische zusammensetzungen und methoden zur inhibierung der beta- amyloidfreisetzung und/oder deren synthese unter verwendung dieser verbindungen
FR2842523A1 (fr) * 2002-07-17 2004-01-23 Sanofi Synthelabo Derives d'acylaminothiazole, leur preparation et leur application en therapeutique
CA2501803A1 (en) * 2002-10-09 2004-04-22 Pfizer Products Inc. Thiazole compounds for the treatment of neurodegenerative disorders

Also Published As

Publication number Publication date
DE60318317T2 (de) 2009-07-09
WO2004009565A3 (fr) 2004-04-08
US20080051436A1 (en) 2008-02-28
FR2842523A1 (fr) 2004-01-23
PT1525193E (pt) 2008-02-25
EP1525193B1 (fr) 2007-12-26
JP2005538086A (ja) 2005-12-15
DE60318317D1 (de) 2008-02-07
US7795289B2 (en) 2010-09-14
US20050182104A1 (en) 2005-08-18
JP4680593B2 (ja) 2011-05-11
AU2003269018A1 (en) 2004-02-09
CY1107903T1 (el) 2013-09-04
ATE382040T1 (de) 2008-01-15
ES2297198T3 (es) 2008-05-01
US7291636B2 (en) 2007-11-06
EP1525193A2 (fr) 2005-04-27
TWI313680B (en) 2009-08-21
TW200413341A (en) 2004-08-01
AR040570A1 (es) 2005-04-13
WO2004009565A2 (fr) 2004-01-29

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