DK1511752T3 - Camptotheciner med modificeret lactonring - Google Patents

Camptotheciner med modificeret lactonring

Info

Publication number: DK1511752T3
Authority: DK; Denmark
Prior art keywords: camptothecins; lactone ring; modified lactone; modified; ring
Prior art date: 2002-05-31

Application number

DK03730480T

Other languages

English (en)

Other versions

DK1511752T5 (da

Inventor

Elena Marastoni

Sergio Penco

Tamara Danelli

Mauro Marzi

Claudio Pisano

Maria O Tinti

Loredana Vesci

Franco Zunino

Domenico Vergani

Walter Cabri

Marco Alpegiani

Martin Gomez Patricio

Original Assignee

Sigma Tau Ind Farmaceuti

Ist Naz Stud Cura Dei Tumori

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-05-31

Filing date

2003-05-28

Publication date

2007-01-29

2003-05-28 Application filed by Sigma Tau Ind Farmaceuti, Ist Naz Stud Cura Dei Tumori filed Critical Sigma Tau Ind Farmaceuti

2007-01-29 Publication of DK1511752T3 publication Critical patent/DK1511752T3/da

2010-06-14 Application granted granted Critical

2010-06-14 Publication of DK1511752T5 publication Critical patent/DK1511752T5/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Public Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Virology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Tropical Medicine & Parasitology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Epoxy Compounds (AREA)

DK03730480.5T 2002-05-31 2003-05-28 Camptotheciner med modificeret lactonring DK1511752T5 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
IT2002RM000305A ITRM20020305A1 (it)	2002-05-31	2002-05-31	Camptotecine con anello lattonico modificato.
PCT/IT2003/000328 WO2003101995A2 (en)	2002-05-31	2003-05-28	Camptothecins with a modified lactone ring

Publications (2)

Publication Number	Publication Date
DK1511752T3 true DK1511752T3 (da)	2007-01-29
DK1511752T5 DK1511752T5 (da)	2010-06-14

Family

ID=11456338

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
DK06116366T DK1719775T3 (da)	2002-05-31	2003-05-28	Camptotheciner med en modificeret lactonring
DK03730480.5T DK1511752T5 (da)	2002-05-31	2003-05-28	Camptotheciner med modificeret lactonring

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
DK06116366T DK1719775T3 (da)	2002-05-31	2003-05-28	Camptotheciner med en modificeret lactonring

Country Status (22)

Country	Link
US (1)	US7273873B2 (da)
EP (2)	EP1719775B1 (da)
JP (1)	JP4693410B2 (da)
KR (1)	KR101042042B1 (da)
CN (1)	CN1656100A (da)
AR (1)	AR040139A1 (da)
AT (2)	ATE403659T1 (da)
AU (2)	AU2003241160B2 (da)
BR (2)	BR0311329A (da)
CA (2)	CA2706635A1 (da)
CY (2)	CY1107311T1 (da)
DE (2)	DE60308368T3 (da)
DK (2)	DK1719775T3 (da)
ES (2)	ES2273002T7 (da)
IT (1)	ITRM20020305A1 (da)
MX (1)	MXPA04011682A (da)
PE (1)	PE20050120A1 (da)
PL (1)	PL374346A1 (da)
PT (2)	PT1719775E (da)
SI (2)	SI1511752T1 (da)
TW (1)	TWI325866B (da)
WO (1)	WO2003101995A2 (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2852606A1 (fr) *	2003-03-18	2004-09-24	Inst Nat Sante Rech Med	Moyens pour inhiber simultanement l'expression de plusieurs genes impliques dans une pathologie
ITRM20030344A1 (it)	2003-07-14	2005-01-15	Ist Naz Stud Cura Dei Tumori	7-n-poliamminoalchil(ossi)imminometilcamptotecine recanti gruppi protettivi.
SI2170900T1 (sl)	2007-08-01	2013-02-28	Sigma-Tau Industrie Farmaceutiche Riunite S.P.A.	Kristalinična oblika II 7-(dimetoksi-metil) kamptotecina, njena uporaba kot intermediat in proizvodi, dobljeni iz le-teh
CN102746314B (zh) *	2011-04-18	2016-07-06	华东师范大学	含有稳定7元内酯环的喜树碱类化合物、制备方法和用途
CN104530066A (zh) *	2015-01-06	2015-04-22	华东师范大学	一类新型高喜树碱衍生物、制备方法和用途
MX2020012066A (es)	2018-05-14	2021-04-28	Nuvation Bio Inc	Compuestos anticancerígenos dirigidos a los receptores hormonales nucleares.
MX2021013774A (es)	2019-05-14	2021-12-10	Nuvation Bio Inc	Compuestos anticancerigenos dirigidos a los receptores hormonales nucleares.
TW202131930A (zh)	2019-11-13	2021-09-01	美商諾維雪碧歐公司	抗癌核荷爾蒙受體標靶化合物
IL306010A (en)	2021-03-23	2023-11-01	Nuvation Bio Inc	Anticancer compounds against the nuclear hormone receptor
AU2022269568A1 (en)	2021-05-03	2023-11-16	Nuvation Bio Inc.	Anti-cancer nuclear hormone receptor-targeting compounds
CN120265635A (zh) *	2022-09-28	2025-07-04	诺维逊生物股份有限公司	抗癌核激素受体靶向化合物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4399276A (en) *	1981-01-09	1983-08-16	Kabushiki Kaisha Yakult Honsha	7-Substituted camptothecin derivatives
JPS57116076A (en) *	1981-01-09	1982-07-19	Yakult Honsha Co Ltd	Novel camptothecin derivative and its preparation
FR2532591A1 (fr)	1982-09-02	1984-03-09	Hutchinson	Nouveau dispositif de securite pour pneumatiques de vehicules ou autres engins
ATE224900T1 (de) *	1995-06-21	2002-10-15	Sod Conseils Rech Applic	Camptothecinanaloge, verfahren zur ihrer herstellung, ihre verwendungals arzneimittel und diese enthaltende pharmazeutische zusammenfassungen
SI1044977T1 (en) *	1999-03-09	2002-08-31	Sigma-Tau Industrie Farmaceutiche Riunite S.P.A.	Camptothecin derivatives having antitumor activity

2002
- 2002-05-31 IT IT2002RM000305A patent/ITRM20020305A1/it unknown
2003
- 2003-05-26 TW TW092114164A patent/TWI325866B/zh not_active IP Right Cessation
- 2003-05-28 BR BR0311329-9A patent/BR0311329A/pt not_active IP Right Cessation
- 2003-05-28 DK DK06116366T patent/DK1719775T3/da active
- 2003-05-28 AT AT06116366T patent/ATE403659T1/de active
- 2003-05-28 PT PT06116366T patent/PT1719775E/pt unknown
- 2003-05-28 MX MXPA04011682A patent/MXPA04011682A/es active IP Right Grant
- 2003-05-28 PL PL03374346A patent/PL374346A1/xx unknown
- 2003-05-28 ES ES03730480T patent/ES2273002T7/es active Active
- 2003-05-28 DE DE60308368T patent/DE60308368T3/de not_active Expired - Lifetime
- 2003-05-28 KR KR1020047016880A patent/KR101042042B1/ko not_active Expired - Fee Related
- 2003-05-28 EP EP06116366A patent/EP1719775B1/en not_active Expired - Lifetime
- 2003-05-28 WO PCT/IT2003/000328 patent/WO2003101995A2/en not_active Ceased
- 2003-05-28 PT PT03730480T patent/PT1511752E/pt unknown
- 2003-05-28 CN CNA038125439A patent/CN1656100A/zh active Pending
- 2003-05-28 JP JP2004509686A patent/JP4693410B2/ja not_active Expired - Fee Related
- 2003-05-28 AU AU2003241160A patent/AU2003241160B2/en not_active Ceased
- 2003-05-28 DE DE60322754T patent/DE60322754D1/de not_active Expired - Lifetime
- 2003-05-28 CA CA2706635A patent/CA2706635A1/en not_active Abandoned
- 2003-05-28 DK DK03730480.5T patent/DK1511752T5/da active
- 2003-05-28 EP EP03730480A patent/EP1511752B3/en not_active Expired - Lifetime
- 2003-05-28 BR BR0311333-7A patent/BR0311333A/pt not_active IP Right Cessation
- 2003-05-28 SI SI200330509T patent/SI1511752T1/sl unknown
- 2003-05-28 CA CA2485201A patent/CA2485201C/en not_active Expired - Fee Related
- 2003-05-28 SI SI200331380T patent/SI1719775T1/sl unknown
- 2003-05-28 ES ES06116366T patent/ES2312090T3/es not_active Expired - Lifetime
- 2003-05-28 US US10/511,724 patent/US7273873B2/en not_active Expired - Fee Related
- 2003-05-28 AT AT03730480T patent/ATE339422T1/de active
- 2003-05-30 PE PE2003000529A patent/PE20050120A1/es not_active Application Discontinuation
- 2003-05-30 AR ARP030101915A patent/AR040139A1/es unknown
2006
- 2006-11-14 CY CY20061101648T patent/CY1107311T1/el unknown
2008
- 2008-10-31 CY CY20081101240T patent/CY1108793T1/el unknown
2009
- 2009-11-12 AU AU2009236044A patent/AU2009236044B8/en not_active Ceased

Also Published As

Publication number	Publication date
PT1511752E (pt)	2007-01-31
AU2009236044A1 (en)	2009-12-03
ES2312090T3 (es)	2009-02-16
DE60322754D1 (de)	2008-09-18
ATE403659T1 (de)	2008-08-15
ATE339422T1 (de)	2006-10-15
KR101042042B1 (ko)	2011-06-16
ES2273002T3 (es)	2007-05-01
CY1107311T1 (el)	2012-11-21
CA2706635A1 (en)	2003-12-11
BR0311329A (pt)	2005-02-22
US7273873B2 (en)	2007-09-25
EP1511752B1 (en)	2006-09-13
JP2005531602A (ja)	2005-10-20
ES2273002T7 (es)	2011-08-01
DE60308368T2 (de)	2007-09-06
DK1719775T3 (da)	2008-11-17
EP1511752A2 (en)	2005-03-09
KR20050036909A (ko)	2005-04-20
PL374346A1 (en)	2005-10-17
WO2003101995A8 (en)	2004-12-23
WO2003101995A2 (en)	2003-12-11
CA2485201A1 (en)	2003-12-11
BR0311333A (pt)	2005-03-15
DK1511752T5 (da)	2010-06-14
US20050154003A1 (en)	2005-07-14
AU2003241160A1 (en)	2003-12-19
EP1511752B3 (en)	2010-03-10
PT1719775E (pt)	2008-09-30
DE60308368T3 (de)	2010-09-16
WO2003101995A3 (en)	2004-02-19
TWI325866B (en)	2010-06-11
EP1719775B1 (en)	2008-08-06
MXPA04011682A (es)	2005-03-31
SI1719775T1 (sl)	2009-04-30
AU2009236044A8 (en)	2011-07-21
CA2485201C (en)	2010-11-02
ITRM20020305A1 (it)	2003-12-01
CY1108793T1 (el)	2014-04-09
DE60308368D1 (de)	2006-10-26
EP1719775A1 (en)	2006-11-08
ITRM20020305A0 (it)	2002-05-31
EP1511752B8 (en)	2007-04-18
AU2009236044B8 (en)	2011-07-21
AR040139A1 (es)	2005-03-16
PE20050120A1 (es)	2005-03-04
AU2003241160B2 (en)	2009-08-20
TW200404806A (en)	2004-04-01
JP4693410B2 (ja)	2011-06-01
CN1656100A (zh)	2005-08-17
SI1511752T1 (sl)	2007-02-28
AU2009236044B2 (en)	2011-03-24

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