|
US6765087B1
(en)
*
|
1992-08-21 |
2004-07-20 |
Vrije Universiteit Brussel |
Immunoglobulins devoid of light chains
|
|
DE69427974T2
(de)
*
|
1993-04-29 |
2001-12-06 |
Unilever N.V., Rotterdam |
Herstellung von antikörpern oder funktionstüchtig gemachten teilen davon, abgeleitet von schweren ketten von immunglobulinen von camelidae
|
|
EP0739981A1
(en)
*
|
1995-04-25 |
1996-10-30 |
Vrije Universiteit Brussel |
Variable fragments of immunoglobulins - use for therapeutic or veterinary purposes
|
|
US20040248201A1
(en)
*
|
1996-06-27 |
2004-12-09 |
Serge Muyldermans |
Recognition molecules interacting specifically with the active site or cleft of a target molecule
|
|
CA2258518C
(en)
*
|
1996-06-27 |
2011-11-22 |
Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw |
Recognition molecules interacting specifically with the active site or cleft of a target molecule
|
|
DK0931097T3
(da)
*
|
1996-10-10 |
2006-01-16 |
Neose Technologies Inc |
Kulhydratoprensning ved anvendelse af omvendt osmose og nanofiltrering
|
|
US20030228310A1
(en)
*
|
1996-12-23 |
2003-12-11 |
Advanced Biotherapy, Inc. |
Treatment of skin diseases
|
|
WO1999037681A2
(en)
*
|
1998-01-26 |
1999-07-29 |
Unilever Plc |
Method for producing antibody fragments
|
|
WO1999055369A1
(en)
*
|
1998-04-28 |
1999-11-04 |
Smithkline Beecham Corporation |
Monoclonal antibodies with reduced immunogenicity
|
|
CA2370351A1
(en)
|
1999-04-22 |
2000-11-02 |
Unilever Plc |
Inhibition of viral infection using monovalent antigen-binding proteins
|
|
US6924359B1
(en)
*
|
1999-07-01 |
2005-08-02 |
Yale University |
Neovascular-targeted immunoconjugates
|
|
EP1196532A1
(en)
|
1999-07-27 |
2002-04-17 |
Unilever N.V. |
Bleaching detergent compositions
|
|
JP2003509438A
(ja)
*
|
1999-09-16 |
2003-03-11 |
ユニリーバー・ナームローゼ・ベンノートシヤープ |
抗フケ剤の送達システム
|
|
US6479280B1
(en)
*
|
1999-09-24 |
2002-11-12 |
Vlaams Interuniversitair Institutuut Voor Biotechnologie Vzw |
Recombinant phages capable of entering host cells via specific interaction with an artificial receptor
|
|
EP1088892A1
(en)
*
|
1999-09-24 |
2001-04-04 |
Vlaams Interuniversitair Instituut voor Biotechnologie vzw. |
Recombinant phages capable of entering host cells via specific interaction with an artificial receptor
|
|
AU1859201A
(en)
|
1999-11-29 |
2001-06-12 |
Unilever Plc |
Immobilisation of proteins
|
|
EP1118669A3
(en)
*
|
1999-12-17 |
2001-08-29 |
Unilever Plc |
Production of camelid antibodies in plants
|
|
ATE428733T1
(de)
|
2000-03-14 |
2009-05-15 |
Unilever Nv |
Variabele domänen der schweren kette eines antikörpers gegen menschliche ernährungslipasen und deren verwendungen
|
|
US6696620B2
(en)
*
|
2000-05-02 |
2004-02-24 |
Epicyte Pharmaceutical, Inc. |
Immunoglobulin binding protein arrays in eukaryotic cells
|
|
US20030190598A1
(en)
*
|
2000-05-26 |
2003-10-09 |
Jasmid Tanha |
Single-domain antigen-binding antibody fragments derived from llama antibodies
|
|
WO2002057445A1
(en)
*
|
2000-05-26 |
2002-07-25 |
National Research Council Of Canada |
Single-domain brain-targeting antibody fragments derived from llama antibodies
|
|
AU2001297872B2
(en)
*
|
2000-11-17 |
2006-11-09 |
University Of Rochester |
In vitro methods of producing and identifying immunoglobulin molecules in eukaryotic cells
|
|
US20050196755A1
(en)
*
|
2000-11-17 |
2005-09-08 |
Maurice Zauderer |
In vitro methods of producing and identifying immunoglobulin molecules in eukaryotic cells
|
|
US20060064782A1
(en)
*
|
2000-12-18 |
2006-03-23 |
Conopco, Inc. |
Production of antibodies
|
|
BR0116283A
(pt)
|
2000-12-19 |
2005-12-13 |
Unilever Nv |
Grânulo de anticorpo, composições detergente, enzimática alvejante de manchas e enzimática de anti-transferência de corante, e, processo para a preparação de um grânulo de anticorpo
|
|
US8372954B2
(en)
*
|
2000-12-22 |
2013-02-12 |
National Research Council Of Canada |
Phage display libraries of human VH fragments
|
|
AU2002305914A1
(en)
|
2001-01-12 |
2002-10-21 |
Chiron Corporation |
Nucleic acid mucosal immunization
|
|
US20030133939A1
(en)
|
2001-01-17 |
2003-07-17 |
Genecraft, Inc. |
Binding domain-immunoglobulin fusion proteins
|
|
US7754208B2
(en)
*
|
2001-01-17 |
2010-07-13 |
Trubion Pharmaceuticals, Inc. |
Binding domain-immunoglobulin fusion proteins
|
|
US7829084B2
(en)
|
2001-01-17 |
2010-11-09 |
Trubion Pharmaceuticals, Inc. |
Binding constructs and methods for use thereof
|
|
US20050069538A1
(en)
*
|
2003-09-18 |
2005-03-31 |
Gregorio Aversa |
Therapeutic binding molecules
|
|
US20040058445A1
(en)
*
|
2001-04-26 |
2004-03-25 |
Ledbetter Jeffrey Alan |
Activation of tumor-reactive lymphocytes via antibodies or genes recognizing CD3 or 4-1BB
|
|
US6861056B2
(en)
*
|
2001-06-05 |
2005-03-01 |
Advanced Biotherapy, Inc. |
Compositions and methods for treating hyperimmune response in the eye
|
|
US20040086508A1
(en)
*
|
2001-06-05 |
2004-05-06 |
Advanced Biotherapy, Inc. |
Treatment of organ transplant rejection
|
|
US20040062768A1
(en)
*
|
2001-06-05 |
2004-04-01 |
Advanced Biotherapy, Inc. |
Compositions and methods for treating hyperimmune response in the eye
|
|
US20050152902A1
(en)
*
|
2001-06-05 |
2005-07-14 |
Advanced Biotherapy, Inc. |
Treatment of diabetic retinopathy
|
|
JP2005289809A
(ja)
|
2001-10-24 |
2005-10-20 |
Vlaams Interuniversitair Inst Voor Biotechnologie Vzw (Vib Vzw) |
突然変異重鎖抗体
|
|
AU2002360068B2
(en)
*
|
2001-12-21 |
2009-09-03 |
Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw |
Method for cloning of variable domain sequences
|
|
JP2005517674A
(ja)
*
|
2002-01-03 |
2005-06-16 |
フラームス・インテルウニフェルシタイル・インステイチュート・フォール・ビオテヒノロヒー・ヴェーゼットウェー |
腫瘍の処置に有用な新規免疫コンジュゲート
|
|
CA2472927A1
(en)
|
2002-01-10 |
2003-07-17 |
Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw |
A novel splice variant of myd88 and uses thereof
|
|
US7736657B2
(en)
|
2002-02-10 |
2010-06-15 |
Apoxis S.A. |
Fusion constructs containing active sections on TNF ligands
|
|
US20030219436A1
(en)
*
|
2002-03-15 |
2003-11-27 |
Ledbetter Jeffrey A. |
Compositions and methods to regulate an immune response using CD83 gene expressed in tumors and using soluble CD83-Ig fusion protein
|
|
US9321832B2
(en)
|
2002-06-28 |
2016-04-26 |
Domantis Limited |
Ligand
|
|
DK1517921T3
(da)
*
|
2002-06-28 |
2006-10-09 |
Domantis Ltd |
Immunglobulin-enkeltvariable antigen-bindende domæner og dobbeltspecifikke konstruktioner deraf
|
|
KR20110025885A
(ko)
|
2002-07-15 |
2011-03-11 |
더 보드 오브 리전츠 오브 더 유니버시티 오브 텍사스 시스템 |
포스파티딜에탄올아민에 결합하는 펩타이드, 및 바이러스 감염을 치료하는데 있어서 이의 용도
|
|
ATE512364T1
(de)
|
2002-08-07 |
2011-06-15 |
Ablynx Nv |
Modulation der blutplättchen-adhäsion basierend auf dem oberflächen-exponierten beta-switch loop des blutplättchen-glycoproteins ib-alpha
|
|
JP4459810B2
(ja)
|
2002-08-14 |
2010-04-28 |
マクロジェニクス,インコーポレーテッド |
FcγRIIB特異的抗体とその利用法
|
|
GB0219720D0
(en)
*
|
2002-08-23 |
2002-10-02 |
Univ Aberdeen |
Polypeptide
|
|
US20040052790A1
(en)
*
|
2002-09-18 |
2004-03-18 |
Advanced Biotherapy, Inc. |
Treatment of schizophrenia
|
|
WO2005044858A1
(en)
|
2003-11-07 |
2005-05-19 |
Ablynx N.V. |
Camelidae single domain antibodies vhh directed against epidermal growth factor receptor and uses therefor
|
|
US9320792B2
(en)
|
2002-11-08 |
2016-04-26 |
Ablynx N.V. |
Pulmonary administration of immunoglobulin single variable domains and constructs thereof
|
|
WO2010081856A1
(en)
|
2009-01-14 |
2010-07-22 |
Ablynx Nv |
Pulmonary administration of immunoglobulin single variable domains and constructs thereof
|
|
US20060034845A1
(en)
|
2002-11-08 |
2006-02-16 |
Karen Silence |
Single domain antibodies directed against tumor necrosis factor alpha and uses therefor
|
|
EP1558647B1
(en)
|
2002-11-08 |
2015-06-10 |
Ablynx N.V. |
Single domain antibodies directed against tumour necrosis factor-alpha and uses therefor
|
|
EP3299393A1
(en)
|
2002-11-08 |
2018-03-28 |
Ablynx N.V. |
Single domain antibodies directed against tumour necrosis factor-alpha and uses therefor
|
|
GB0230203D0
(en)
*
|
2002-12-27 |
2003-02-05 |
Domantis Ltd |
Fc fusion
|
|
EP1437764A1
(en)
*
|
2003-01-10 |
2004-07-14 |
S.O.I. Tec Silicon on Insulator Technologies S.A. |
A compliant substrate for a heteroepitaxy, a heteroepitaxial structure and a method for fabricating a compliant substrate
|
|
NZ540771A
(en)
|
2003-01-10 |
2009-05-31 |
Ablynx Nv |
Recombinant VHH single domain antibody from camelidae against von willebrand factor (vWF) or against collagen
|
|
AU2004229501B2
(en)
|
2003-04-11 |
2011-08-18 |
Medimmune, Llc |
Recombinant IL-9 antibodies and uses thereof
|
|
DK1639011T3
(da)
|
2003-06-30 |
2009-02-16 |
Domantis Ltd |
Pegylerede enkelt-domæne antistoffer (dAb)
|
|
US7754209B2
(en)
|
2003-07-26 |
2010-07-13 |
Trubion Pharmaceuticals |
Binding constructs and methods for use thereof
|
|
PL3095793T3
(pl)
|
2003-07-28 |
2020-09-07 |
Genentech, Inc. |
Redukcja wycieku białka A w trakcie chromatografii powinowactwa z białkiem A
|
|
EP2128270B1
(en)
|
2003-08-08 |
2012-10-03 |
Genenews Inc. |
Osteoarthritis biomarkers and uses thereof
|
|
WO2005081687A2
(en)
*
|
2003-09-30 |
2005-09-09 |
Centocor, Inc. |
Human hinge core mimetibodies, compositions, methods and uses
|
|
EP1682179A4
(en)
|
2003-11-05 |
2008-09-03 |
Palingen Inc |
IMPROVED B-CELL CYTOTOXICITY OF CDIM BINDING ANTIBODY
|
|
ES2616337T3
(es)
*
|
2003-12-12 |
2017-06-12 |
Government Of The United States Of America, As Repr. By The Secr. Of The Dept. Of Health And Human Services And His Successors |
Un epítopo de linfocito T citotóxico humano y su epítopo agonista del número no variable de secuencias de repetición en tándem de MUC-1
|
|
US7785903B2
(en)
|
2004-04-09 |
2010-08-31 |
Genentech, Inc. |
Variable domain library and uses
|
|
WO2005105984A2
(en)
*
|
2004-04-12 |
2005-11-10 |
The Trustees Of The University Of Pennsylvania |
Culture conditions and growth factors affecting fate determination, self-renewal and expansion of mouse spermatogonial stem cells
|
|
CN1942203A
(zh)
*
|
2004-06-04 |
2007-04-04 |
金克克国际有限公司 |
使用抗体重链的筛选方法
|
|
US20050276806A1
(en)
*
|
2004-06-15 |
2005-12-15 |
Advanced Biotherapy, Inc. |
Treatment of autism
|
|
US20050276807A1
(en)
*
|
2004-06-15 |
2005-12-15 |
Advanced Biotherapy, Inc. |
Treatment of acne
|
|
WO2006008548A2
(en)
|
2004-07-22 |
2006-01-26 |
Erasmus University Medical Centre Rotterdam |
Binding molecules
|
|
GB2416768A
(en)
*
|
2004-07-22 |
2006-02-08 |
Univ Erasmus |
Heavy chain immunoglobulin complexes
|
|
US20060177445A1
(en)
*
|
2004-08-16 |
2006-08-10 |
Boris Skurkovich |
Treatment of inflammatory skin diseases
|
|
US7563443B2
(en)
|
2004-09-17 |
2009-07-21 |
Domantis Limited |
Monovalent anti-CD40L antibody polypeptides and compositions thereof
|
|
CN101724071A
(zh)
|
2004-10-08 |
2010-06-09 |
杜门蒂斯有限公司 |
抗肿瘤坏死因子受体1的单域抗体及其使用方法
|
|
US7462454B2
(en)
|
2004-10-12 |
2008-12-09 |
Advanced Biotherapy, Inc. |
Treatment of herpes
|
|
BRPI0518151A2
(pt)
*
|
2004-10-13 |
2009-06-16 |
Ablynx Nv |
polipetìdeos contra amiloide-beta, ácido nucléico que codifica tal polipetìdeo, composição compreendendo tal polipetìdeo, método para produzir um polipetìdeo e uso do mesmo
|
|
US20060121042A1
(en)
|
2004-10-27 |
2006-06-08 |
Medimmune, Inc. |
Modulation of antibody specificity by tailoring the affinity to cognate antigens
|
|
ATE473446T1
(de)
|
2005-01-14 |
2010-07-15 |
Ablynx Nv |
Verfahren und testvorrichtungen zur unterscheidung verschiedener formen von krankheiten und leiden, die durch thrombocytopenia und/oder durch spontane interaktionen zwischen dem von-willebrand-faktor und plättchen gekennzeichnet sind
|
|
CA2595682A1
(en)
*
|
2005-01-31 |
2006-08-03 |
Ablynx N.V. |
Method for generating variable domain sequences of heavy chain antibodies
|
|
CN103497993A
(zh)
|
2005-02-07 |
2014-01-08 |
基因信息公司 |
轻度骨关节炎生物标志物及其用途
|
|
AU2006213686A1
(en)
|
2005-02-09 |
2006-08-17 |
Avi Bio Pharma, Inc. |
Antisense composition and method for treating muscle atrophy
|
|
JP5032458B2
(ja)
*
|
2005-03-11 |
2012-09-26 |
シンジェンタ リミテッド |
有害生物防除
|
|
AU2006239315B2
(en)
|
2005-04-28 |
2012-03-01 |
Ventana Medical Systems, Inc. |
Enzymes conjugated to antiobodies via a PEG heterobifuctional linker
|
|
US20060246524A1
(en)
*
|
2005-04-28 |
2006-11-02 |
Christina Bauer |
Nanoparticle conjugates
|
|
CN103254309B
(zh)
|
2005-05-18 |
2017-09-26 |
埃博灵克斯股份有限公司 |
针对肿瘤坏死因子α的改进的纳米体TM
|
|
CN101213214B
(zh)
|
2005-05-20 |
2014-06-25 |
埃博灵克斯股份有限公司 |
针对冯威勒布兰特因子的单一结构域vhh抗体
|
|
DE102005023617A1
(de)
|
2005-05-21 |
2006-11-23 |
Aspre Ag |
Verfahren zum Mischen von Farben in einem Display
|
|
HUE026303T2
(hu)
*
|
2005-07-25 |
2016-06-28 |
Emergent Product Dev Seattle |
B-sejt csökkentés CD37-specifikus és CD20-specifikus kapcsoló molekulák alkalmazásával
|
|
EP2354160A1
(en)
|
2005-08-31 |
2011-08-10 |
Schering Corporation |
Engineered anti-IL-23-antibodies
|
|
CN101296706B
(zh)
|
2005-09-01 |
2011-11-30 |
先灵公司 |
Il-23和il-17拮抗剂治疗自身免疫性眼部炎性疾病的用途
|
|
WO2007036021A1
(en)
*
|
2005-09-27 |
2007-04-05 |
National Research Council Of Canada |
Blood-brain barrier epitopes and uses thereof
|
|
CA2624081C
(en)
*
|
2005-09-29 |
2014-09-16 |
Medimmune, Inc. |
Method of identifying membrane ig specific antibodies and use thereof for targeting immunoglobulin-producing precursor cells
|
|
US7526409B2
(en)
*
|
2005-10-07 |
2009-04-28 |
Oracle International Corporation |
Automatic performance statistical comparison between two periods
|
|
GB0521139D0
(en)
|
2005-10-18 |
2005-11-23 |
Univ Sheffield |
Therapeutic agent
|
|
TW200730825A
(en)
|
2005-10-21 |
2007-08-16 |
Genenews Inc |
Method and apparatus for correlating levels of biomarker products with disease
|
|
GB0522460D0
(en)
*
|
2005-11-03 |
2005-12-14 |
Prendergast Patrick T |
Composition and method for the treatment of avian influenza
|
|
EP3095467B1
(en)
*
|
2005-11-23 |
2020-05-06 |
Ventana Medical Systems, Inc. |
Antibody-enzyme conjugate
|
|
US10183986B2
(en)
|
2005-12-15 |
2019-01-22 |
Industrial Technology Research Institute |
Trimeric collagen scaffold antibodies
|
|
EP1983823A1
(en)
|
2006-01-17 |
2008-10-29 |
VIB vzw |
Inhibitors of prolyl-hydroxylase 1 for the treatment of skeletal muscle degeneration
|
|
WO2007085814A1
(en)
*
|
2006-01-24 |
2007-08-02 |
Domantis Limited |
Fusion proteins that contain natural junctions
|
|
TWI417301B
(zh)
|
2006-02-21 |
2013-12-01 |
Wyeth Corp |
對抗人類介白素-22(il-22)之抗體及其用途
|
|
TW200744634A
(en)
*
|
2006-02-21 |
2007-12-16 |
Wyeth Corp |
Methods of using antibodies against human IL-22
|
|
US7504106B2
(en)
*
|
2006-03-14 |
2009-03-17 |
Boris Skurkovich |
Method and composition for treatment of renal failure with antibodies and their equivalents as partial or complete replacement for dialysis
|
|
EP1999147A1
(en)
*
|
2006-03-27 |
2008-12-10 |
Ablynx N.V. |
Medical delivery device for therapeutic proteins based on single domain antibodies
|
|
MX2008013397A
(es)
*
|
2006-04-21 |
2009-03-27 |
Wyeth Corp |
Analisis de perfilamiento de expresion diferencial de fenotipos de cultivo celular y usos de los mismos.
|
|
RU2008147398A
(ru)
|
2006-05-02 |
2010-06-10 |
Актогеникс Н.В. (Be) |
Доставка пептидов, связанных с ожирением, через кишечник посредством микроорганизмов
|
|
CN105837690A
(zh)
|
2006-06-12 |
2016-08-10 |
新兴产品开发西雅图有限公司 |
具有效应功能的单链多价结合蛋白
|
|
EP2037961B1
(en)
|
2006-06-14 |
2015-11-11 |
MacroGenics, Inc. |
Methods for the treatment of autoimmune disorders using monoclonal antibodies with reduced toxicity
|
|
EP2505209A1
(en)
|
2006-06-26 |
2012-10-03 |
MacroGenics, Inc. |
Fcgamma-RIIB-specific antibodies and methods of the use thereof
|
|
DK2041270T3
(da)
|
2006-07-13 |
2014-01-27 |
Wyeth Llc |
Fremstilling af glycoproteiner
|
|
EP2484696B1
(en)
|
2006-08-28 |
2017-08-16 |
Kyowa Hakko Kirin Co., Ltd. |
Antagonistic hLIGHT-specific human monoclonal antibodies
|
|
EP3028716B1
(en)
|
2006-10-10 |
2020-09-16 |
Regenesance B.V. |
Complement inhibition for improved nerve regeneration
|
|
GB0621513D0
(en)
|
2006-10-30 |
2006-12-06 |
Domantis Ltd |
Novel polypeptides and uses thereof
|
|
DK2078197T3
(da)
|
2006-11-01 |
2016-05-23 |
Ventana Med Syst Inc |
Haptener, haptenkonjugater, sammensætninger deraf og fremgangsmåde til deres fremstilling og anvendelse
|
|
EP2092080A1
(en)
|
2006-11-07 |
2009-08-26 |
Vib Vzw |
Diagnosis and treatment of t-cell acute lymphoblastic leukemia
|
|
CA2670471A1
(en)
|
2006-11-22 |
2008-06-05 |
Adnexus, A Bristol-Myers Squibb R&D Company (A Delaware Corporation) |
Targeted therapeutics based on engineered proteins for tyrosine kinases receptors, including igf-ir
|
|
JP2010511397A
(ja)
*
|
2006-12-05 |
2010-04-15 |
アブリンクス エン.ヴェー. |
血清タンパク質と結合可能なペプチド
|
|
KR20090088950A
(ko)
|
2006-12-14 |
2009-08-20 |
쉐링 코포레이션 |
가공된 항-tslp 항체
|
|
EP2514767A1
(en)
|
2006-12-19 |
2012-10-24 |
Ablynx N.V. |
Amino acid sequences directed against a metalloproteinase from the ADAM family and polypeptides comprising the same for the treatment of ADAM-related diseases and disorders
|
|
EP2115004A2
(en)
|
2006-12-19 |
2009-11-11 |
Ablynx N.V. |
Amino acid sequences directed against gpcrs and polypeptides comprising the same for the treatment of gpcr-related diseases and disorders
|
|
US9023352B2
(en)
|
2007-02-20 |
2015-05-05 |
Tufts University |
Methods, compositions and kits for treating a subject using a recombinant heteromultimeric neutralizing binding protein
|
|
JP2010518839A
(ja)
*
|
2007-02-21 |
2010-06-03 |
アブリンクス エン.ヴェー. |
血管内皮増殖因子に指向性を有するアミノ酸配列、及び過度の及び/もしくは病的な血管形成又は血管新生を特徴とする症状及び疾患を治療するためにこれを含むポリペプチド
|
|
CA2678863A1
(en)
|
2007-02-23 |
2008-08-28 |
Schering Corporation |
Engineered anti-il-23p19 antibodies
|
|
MX2009009079A
(es)
|
2007-02-23 |
2009-08-31 |
Schering Corp |
Anticuerpos anti-il-23p19 de ingenieria.
|
|
CN101675076B
(zh)
|
2007-02-28 |
2013-09-18 |
默沙东公司 |
工程化的抗il-23r抗体
|
|
EP2417974A1
(en)
|
2007-02-28 |
2012-02-15 |
Schering Corporation |
Combination therapy for treatment of immune disorders
|
|
KR20090127326A
(ko)
|
2007-03-02 |
2009-12-10 |
와이어쓰 |
폴리펩티드의 생산을 위한 세포 배양물 중에서 구리 및 글루타메이트의 용도
|
|
DK2308514T3
(da)
|
2007-03-23 |
2013-09-02 |
To Bbb Holding B V |
Konjugater til målrettet lægemiddeltransport gennem blod-hjerne barrieren
|
|
TW200902708A
(en)
|
2007-04-23 |
2009-01-16 |
Wyeth Corp |
Methods of protein production using anti-senescence compounds
|
|
CA2685213C
(en)
|
2007-05-04 |
2017-02-21 |
Technophage, Investigacao E Desenvolvimento Em Biotecnologia, Sa |
Engineered rabbit antibody variable domains and uses thereof
|
|
DK3072525T3
(da)
|
2007-05-14 |
2018-04-30 |
Astrazeneca Ab |
Fremgangsmåder til reducering af niveauer af basofile celler
|
|
EP3561513A1
(en)
|
2007-05-23 |
2019-10-30 |
Ventana Medical Systems, Inc. |
Polymeric carriers for immunohistochemistry and in situ hybridization
|
|
EP2602323B1
(en)
|
2007-06-01 |
2018-02-28 |
Open Monoclonal Technology, Inc. |
Compositions and methods for inhibiting endogenous immunoglobin genes and producing transgenic human idiotype antibodies
|
|
WO2008157299A2
(en)
*
|
2007-06-15 |
2008-12-24 |
Wyeth |
Differential expression profiling analysis of cell culture phenotypes and uses thereof
|
|
JP5240870B2
(ja)
|
2007-07-03 |
2013-07-17 |
アブリンクス エン.ヴェー. |
改善した免疫グロブリン配列を提供する方法
|
|
EP2170960B1
(en)
|
2007-07-13 |
2015-07-29 |
Bac Ip B.V. |
Single-domain antigen-binding proteins that bind mammalian igg
|
|
US20100291593A1
(en)
|
2007-07-13 |
2010-11-18 |
Powell William C |
Method of identifying diagnostic reagents
|
|
EP3327132A3
(en)
|
2007-08-09 |
2018-07-18 |
Wyeth LLC |
Use of perfusion to enhance production of fed-batch cell culture in bioreactors
|
|
ES2667729T3
(es)
|
2007-09-26 |
2018-05-14 |
Ucb Biopharma Sprl |
Fusiones de anticuerpos con doble especificidad
|
|
TWI489993B
(zh)
|
2007-10-12 |
2015-07-01 |
Novartis Ag |
骨硬化素(sclerostin)抗體組合物及使用方法
|
|
CA2702637A1
(en)
|
2007-10-22 |
2009-04-30 |
Schering Corporation |
Fully human anti-vegf antibodies and methods of using
|
|
ES2560532T3
(es)
|
2007-11-02 |
2016-02-19 |
Novartis Ag |
Moléculas y métodos de modulación de la proteína 6 relacionada con el receptor de lipoproteína de baja densidad (LRP6)
|
|
JP5514399B2
(ja)
*
|
2007-11-02 |
2014-06-04 |
国立大学法人 岡山大学 |
無機硫黄化合物加水分解酵素の製造方法
|
|
WO2010008411A1
(en)
|
2007-11-09 |
2010-01-21 |
The Salk Institute For Biological Studies |
Use of tam receptor inhibitors as immunoenhancers and tam activators as immunosuppressors
|
|
CN101970490A
(zh)
|
2007-11-27 |
2011-02-09 |
埃博灵克斯股份有限公司 |
针对异二聚体细胞因子和/或其受体的氨基酸序列以及包括所述氨基酸序列的多肽
|
|
US9308257B2
(en)
|
2007-11-28 |
2016-04-12 |
Medimmune, Llc |
Protein formulation
|
|
US20090186358A1
(en)
*
|
2007-12-21 |
2009-07-23 |
Wyeth |
Pathway Analysis of Cell Culture Phenotypes and Uses Thereof
|
|
JP5889533B2
(ja)
|
2008-01-31 |
2016-03-22 |
ザ ガバメント オブ ザ ユナイテッド ステイツ オブ アメリカ, アズ リプレゼンテッド バイ ザ セクレタリー, デパートメント オブ ヘルス アンド ヒューマン サービシーズ |
改変された抗体定常ドメイン分子
|
|
CA2717015A1
(en)
|
2008-03-05 |
2009-09-11 |
Ablynx Nv |
Novel antigen binding dimer-complexes, methods of making and uses thereof
|
|
GB0809069D0
(en)
|
2008-05-19 |
2008-06-25 |
Univ Leuven Kath |
Gene signatures
|
|
WO2009121948A2
(en)
|
2008-04-03 |
2009-10-08 |
Vib Vzw |
Single domain antibodies capable of modulating bace activity
|
|
US9908943B2
(en)
|
2008-04-03 |
2018-03-06 |
Vib Vzw |
Single domain antibodies capable of modulating BACE activity
|
|
WO2009124931A2
(en)
|
2008-04-07 |
2009-10-15 |
Ablynx Nv |
Amino acid sequences directed against the notch pathways and uses thereof
|
|
AU2009234277B2
(en)
|
2008-04-11 |
2014-12-04 |
Aptevo Research And Development Llc |
CD37 immunotherapeutic and combination with bifunctional chemotherapeutic thereof
|
|
WO2009127691A1
(en)
|
2008-04-17 |
2009-10-22 |
Ablynx N.V. |
Peptides capable of binding to serum proteins and compounds, constructs and polypeptides comprising the same
|
|
MX2010011957A
(es)
|
2008-05-02 |
2011-03-04 |
Novartis Ag Star |
Moleculas de union basadas en fibronectina mejoradas y usos de las mismas.
|
|
EP2799448A1
(en)
|
2008-05-22 |
2014-11-05 |
Bristol-Myers Squibb Company |
Multivalent fibronectin based scaffold domain proteins
|
|
US8703490B2
(en)
|
2008-06-05 |
2014-04-22 |
Ventana Medical Systems, Inc. |
Compositions comprising nanomaterials and method for using such compositions for histochemical processes
|
|
GB2461546B
(en)
*
|
2008-07-02 |
2010-07-07 |
Argen X Bv |
Antigen binding polypeptides
|
|
US8444976B2
(en)
|
2008-07-02 |
2013-05-21 |
Argen-X B.V. |
Antigen binding polypeptides
|
|
US8168759B2
(en)
|
2008-07-18 |
2012-05-01 |
Bristol-Myers Squibb Company |
Compositions monovalent for CD28 binding and methods of use
|
|
EP2313436B1
(en)
|
2008-07-22 |
2014-11-26 |
Ablynx N.V. |
Amino acid sequences directed against multitarget scavenger receptors and polypeptides
|
|
WO2010015608A1
(en)
|
2008-08-05 |
2010-02-11 |
Novartis Ag |
Compositions and methods for antibodies targeting complement protein c5
|
|
US20100136584A1
(en)
*
|
2008-09-22 |
2010-06-03 |
Icb International, Inc. |
Methods for using antibodies and analogs thereof
|
|
WO2010033913A1
(en)
*
|
2008-09-22 |
2010-03-25 |
Icb International, Inc. |
Antibodies, analogs and uses thereof
|
|
US20100075329A1
(en)
|
2008-09-23 |
2010-03-25 |
O'toole Margot |
Methods for predicting production of activating signals by cross-linked binding proteins
|
|
EP2346900A1
(en)
|
2008-10-29 |
2011-07-27 |
Wyeth LLC |
Methods for purification of single domain antigen binding molecules
|
|
EP3011953A1
(en)
|
2008-10-29 |
2016-04-27 |
Ablynx N.V. |
Stabilised formulations of single domain antigen binding molecules
|
|
CA2747644C
(en)
|
2008-12-19 |
2023-01-24 |
Ablynx N.V. |
Method for generation of immunoglobulin sequences
|
|
EP2379710A1
(en)
|
2008-12-19 |
2011-10-26 |
Schering Corporation |
Feed supplement for mammalian cell culture and methods of use
|
|
US20100189919A1
(en)
*
|
2009-01-27 |
2010-07-29 |
Xerox Corporation |
Imaging System And Process Using Monoclonal Antibodies
|
|
CA2750520C
(en)
|
2009-02-04 |
2017-12-05 |
Molecular Innovations |
Methods for screening candidate agents for modulating prorenin and renin, assays for detecting prorenin, and antibodies used therein
|
|
US10005830B2
(en)
|
2009-03-05 |
2018-06-26 |
Ablynx N.V. |
Antigen binding dimer-complexes, methods of making/avoiding and uses thereof
|
|
EP2230515B1
(en)
*
|
2009-03-16 |
2014-12-17 |
Agilent Technologies, Inc. |
Passivation of surfaces after ligand coupling
|
|
GB0905023D0
(en)
|
2009-03-24 |
2009-05-06 |
Univ Erasmus Medical Ct |
Binding molecules
|
|
JP6159528B2
(ja)
|
2009-03-24 |
2017-07-05 |
ワイス・エルエルシー |
高濃縮のタンパク質治療薬を生成するための膜蒸発
|
|
EP2417163B1
(en)
|
2009-04-10 |
2019-02-27 |
Ablynx N.V. |
Improved amino acid sequences directed against il-6r and polypeptides comprising the same for the treatment of il-6r related diseases and disorders
|
|
NO2424895T3
(da)
|
2009-04-27 |
2018-02-03 |
|
|
|
BRPI1016055A2
(pt)
|
2009-04-27 |
2016-05-10 |
Novartis Ag |
composição e métodos de uso para anticorpos terapêuticos específicos para a subunidade beta i do receptor de il-12
|
|
DK2982690T3
(da)
|
2009-04-30 |
2021-04-12 |
Ablynx Nv |
Fremgangsmåde til fremstilling af domæne-antistoffer
|
|
EP2432499A2
(en)
|
2009-05-20 |
2012-03-28 |
Schering Corporation |
Modulation of pilr receptors to treat microbial infections
|
|
MX340541B
(es)
|
2009-06-05 |
2016-07-13 |
Alblynx Nv |
Secuencias de aminoacidos mejoradas dirigidas contra virus sincitial respiratorio humano y polipeptidos que comprenden las mismas para la prevencion y/o tratamiento de infecciones del tracto respiratorio.
|
|
US9290577B2
(en)
|
2009-07-03 |
2016-03-22 |
Avipep Pty Limited |
Immuno-conjugates and methods for producing them
|
|
HUE051430T2
(hu)
|
2009-07-10 |
2021-03-01 |
Ablynx Nv |
Eljárás variábilis domének elõállítására
|
|
CA2768330A1
(en)
|
2009-07-28 |
2011-02-03 |
F. Hoffmann-La Roche Ag |
Non-invasive in vivo optical imaging method
|
|
EP2459594A1
(en)
|
2009-07-31 |
2012-06-06 |
N.V. Organon |
Fully human antibodies to btla
|
|
WO2011018421A1
(en)
|
2009-08-10 |
2011-02-17 |
Morphosys Ag |
Novel screening strategies for the identification of binders
|
|
US9255148B2
(en)
|
2009-09-03 |
2016-02-09 |
Cancer Research Technology Limited |
CLEC14A inhibitors
|
|
CA2772613C
(en)
|
2009-09-03 |
2020-03-10 |
Schering Corporation |
Anti-gitr antibodies
|
|
PT2473528E
(pt)
|
2009-09-03 |
2015-03-04 |
Ablynx NV |
Formulações estáveis de polipéptidos e seus usos
|
|
WO2011029823A1
(en)
|
2009-09-09 |
2011-03-17 |
Novartis Ag |
Monoclonal antibody reactive with cd63 when expressed at the surface of degranulated mast cells
|
|
GB201005063D0
(en)
|
2010-03-25 |
2010-05-12 |
Ucb Pharma Sa |
Biological products
|
|
UY32917A
(es)
|
2009-10-02 |
2011-04-29 |
Boehringer Ingelheim Int |
Moléculas de unión a dll-4
|
|
US20110172398A1
(en)
|
2009-10-02 |
2011-07-14 |
Boehringer Ingelheim International Gmbh |
Bispecific binding molecules for anti-angiogenesis therapy
|
|
US20110117113A1
(en)
|
2009-10-09 |
2011-05-19 |
Gerald Beste |
Immunoglobulin single variable domain directed against human cxcr4 and other cell associated proteins and methods to generate them
|
|
WO2011045079A1
(en)
|
2009-10-15 |
2011-04-21 |
Intercell Ag |
Hepatitis b virus specific human antibodies
|
|
WO2011049449A1
(en)
|
2009-10-22 |
2011-04-28 |
University Of Twente |
Vhh for application in tissue repair, organ regeneration, organ replacement and tissue engineering
|
|
WO2011050242A1
(en)
|
2009-10-23 |
2011-04-28 |
Millennium Pharmaceuticals, Inc. |
Anti-gcc antibody molecules and related compositions and methods
|
|
ES2860453T3
(es)
|
2009-10-30 |
2021-10-05 |
Novartis Ag |
Bibliotecas universales del dominio de unión del lado inferior de la fibronectina de tipo III
|
|
WO2011051327A2
(en)
|
2009-10-30 |
2011-05-05 |
Novartis Ag |
Small antibody-like single chain proteins
|
|
WO2011051466A1
(en)
|
2009-11-02 |
2011-05-05 |
Novartis Ag |
Anti-idiotypic fibronectin-based binding molecules and uses thereof
|
|
WO2011056772A1
(en)
|
2009-11-04 |
2011-05-12 |
Schering Corporation |
Engineered anti-tslp antibody
|
|
CN102640001A
(zh)
|
2009-11-05 |
2012-08-15 |
诺瓦提斯公司 |
预测纤维化进展的生物标记物
|
|
US9644022B2
(en)
|
2009-11-30 |
2017-05-09 |
Ablynx N.V. |
Amino acid sequences directed against human respiratory syncytial virus (HRSV) and polypeptides comprising the same for the prevention and/or treatment of respiratory tract infections
|
|
US8754287B2
(en)
|
2009-12-10 |
2014-06-17 |
Regeneron Pharmaceuticals, Inc. |
Mice that make heavy chain antibodies
|
|
WO2011072266A2
(en)
|
2009-12-11 |
2011-06-16 |
Atyr Pharma, Inc. |
Aminoacyl trna synthetases for modulating hematopoiesis
|
|
US8962807B2
(en)
|
2009-12-14 |
2015-02-24 |
Ablynx N.V. |
Single variable domain antibodies against OX40L, constructs and therapeutic use
|
|
WO2011084357A1
(en)
|
2009-12-17 |
2011-07-14 |
Schering Corporation |
Modulation of pilr to treat immune disorders
|
|
SG181814A1
(en)
|
2009-12-23 |
2012-07-30 |
Avipep Pty Ltd |
Immuno-conjugates and methods for producing them 2
|
|
WO2011083140A1
(en)
|
2010-01-08 |
2011-07-14 |
Ablynx Nv |
Immunoglobulin single variable domain directed against human cxcr4
|
|
TWI513466B
(zh)
|
2010-01-20 |
2015-12-21 |
Boehringer Ingelheim Int |
抗凝血劑解毒劑
|
|
WO2011095545A1
(en)
|
2010-02-05 |
2011-08-11 |
Ablynx Nv |
Peptides capable of binding to serum albumin and compounds, constructs and polypeptides comprising the same
|
|
US9120855B2
(en)
|
2010-02-10 |
2015-09-01 |
Novartis Ag |
Biologic compounds directed against death receptor 5
|
|
JP2013519869A
(ja)
|
2010-02-10 |
2013-05-30 |
ノバルティス アーゲー |
筋肉成長のための方法および化合物
|
|
EP2533814A2
(en)
|
2010-02-11 |
2012-12-19 |
Ablynx N.V. |
Delivery of immunoglobulin variable domains and constructs thereof
|
|
HRP20191071T1
(hr)
|
2010-02-11 |
2019-09-20 |
Ablynx N.V. |
Postupci i pripravci za pripremu aerosola
|
|
WO2011106583A1
(en)
|
2010-02-26 |
2011-09-01 |
Ventana Medical Systems, Inc. |
Polytag probes
|
|
WO2011107507A1
(en)
|
2010-03-03 |
2011-09-09 |
Boehringer Ingelheim International Gmbh |
Biparatopic abeta binding polypeptides
|
|
WO2011117423A1
(en)
|
2010-03-26 |
2011-09-29 |
Ablynx N.V. |
Immunoglobulin single variable domains directed against cxcr7
|
|
US20130041349A1
(en)
|
2010-03-26 |
2013-02-14 |
Westfaelische Wilhelms-Universitaet Muenster |
Substitute therapy for glucocorticoids
|
|
US9101674B2
(en)
|
2010-03-29 |
2015-08-11 |
Vib Vzw |
Targeting and in vivo imaging of tumor-associated macrophages
|
|
US9556273B2
(en)
|
2010-03-29 |
2017-01-31 |
Vib Vzw |
Anti-macrophage mannose receptor single variable domains for targeting and in vivo imaging of tumor-associated macrophages
|
|
WO2011124612A1
(en)
|
2010-04-06 |
2011-10-13 |
Vib Vzw |
Specific delivery of agrochemicals
|
|
GB201105584D0
(en)
|
2011-04-01 |
2011-05-18 |
Imp Innovations Ltd |
Cancer methods
|
|
CA2796087A1
(en)
|
2010-04-20 |
2011-10-27 |
Ventana Medical Systems, Inc. |
Two-color chromogenic in situ hybridization
|
|
JP6066900B2
(ja)
|
2010-04-26 |
2017-01-25 |
エータイアー ファーマ, インコーポレイテッド |
システイニルtRNA合成酵素のタンパク質フラグメントに関連した治療用、診断用および抗体組成物の革新的発見
|
|
US8961960B2
(en)
|
2010-04-27 |
2015-02-24 |
Atyr Pharma, Inc. |
Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of isoleucyl tRNA synthetases
|
|
JP6008837B2
(ja)
|
2010-04-28 |
2016-10-19 |
エータイアー ファーマ, インコーポレイテッド |
アラニルtRNA合成酵素のタンパク質フラグメントに関連した治療用、診断用および抗体組成物の革新的発見
|
|
WO2011139907A2
(en)
|
2010-04-29 |
2011-11-10 |
Atyr Pharma, Inc. |
Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of valyl trna synthetases
|
|
US8986680B2
(en)
|
2010-04-29 |
2015-03-24 |
Atyr Pharma, Inc. |
Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of Asparaginyl tRNA synthetases
|
|
KR101800913B1
(ko)
|
2010-04-30 |
2017-12-20 |
알렉시온 파마슈티칼스, 인코포레이티드 |
항-c5a 항체들과 이 항체들을 이용하는 방법
|
|
JP6008841B2
(ja)
|
2010-05-03 |
2016-10-19 |
エータイアー ファーマ, インコーポレイテッド |
メチオニルtRNA合成酵素のタンパク質フラグメントに関連した治療用、診断用および抗体組成物の革新的発見
|
|
AU2011248227B2
(en)
|
2010-05-03 |
2016-12-01 |
Pangu Biopharma Limited |
Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of phenylalanyl-alpha-tRNA synthetases
|
|
US8961961B2
(en)
|
2010-05-03 |
2015-02-24 |
a Tyr Pharma, Inc. |
Innovative discovery of therapeutic, diagnostic, and antibody compositions related protein fragments of arginyl-tRNA synthetases
|
|
EP2566499B1
(en)
|
2010-05-04 |
2017-01-25 |
aTyr Pharma, Inc. |
Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of p38 multi-trna synthetase complex
|
|
EP2566967B1
(en)
|
2010-05-04 |
2016-07-06 |
The Brigham and Women's Hospital, Inc. |
Cadherin-11 antagonist for the treatment of fibrosis
|
|
US8877188B2
(en)
|
2010-05-04 |
2014-11-04 |
The Brigham And Women's Hospital, Inc. |
Detection and treatment of non-dermal fibrosis
|
|
US9290573B2
(en)
|
2010-05-06 |
2016-03-22 |
Novartis Ag |
Therapeutic low density lipoprotein-related protein 6 (LRP6) multivalent antibodies
|
|
ES2659406T3
(es)
|
2010-05-06 |
2018-03-15 |
Novartis Ag |
Composiciones y procedimientos de uso para anticuerpos terapéuticos contra la proteína 6 relacionada con las lipoproteínas de baja densidad (LRP6)
|
|
EP2567234B1
(en)
|
2010-05-07 |
2018-09-19 |
F.Hoffmann-La Roche Ag |
Diagnostic method for the detection of cells ex vivo
|
|
EP2568996B1
(en)
|
2010-05-14 |
2017-10-04 |
aTyr Pharma, Inc. |
Therapeutic, diagnostic, and antibody compositions related to protein fragments of phenylalanyl-beta-trna synthetases
|
|
SG185354A1
(en)
|
2010-05-20 |
2012-12-28 |
Ablynx Nv |
Biological materials related to her3
|
|
CN103096913B
(zh)
|
2010-05-27 |
2017-07-18 |
Atyr 医药公司 |
与谷氨酰胺酰‑tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的创新发现
|
|
EP2585110A4
(en)
|
2010-06-22 |
2014-01-22 |
Univ Colorado Regents |
ANTIBODIES AGAINST THE C3D FRAGMENT OF THE COMPLEMENT COMPONENT 3
|
|
WO2011161263A1
(en)
|
2010-06-25 |
2011-12-29 |
Ablynx Nv |
Pharmaceutical compositions for cutaneous administration
|
|
AU2011274369A1
(en)
|
2010-07-02 |
2012-12-06 |
Ventana Medical Systems, Inc. |
Hapten conjugates for target detection
|
|
US20130149297A1
(en)
|
2010-07-02 |
2013-06-13 |
Vib Vzw |
Role of fragile x mental retardation gene and protein in cancer metastasis
|
|
CA2804416C
(en)
|
2010-07-12 |
2020-04-28 |
Atyr Pharma, Inc. |
Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of glycyl-trna synthetases
|
|
AU2011277983C1
(en)
|
2010-07-16 |
2016-09-29 |
Ablynx Nv |
Modified single domain antigen binding molecules and uses thereof
|
|
GB201014715D0
(en)
|
2010-09-06 |
2010-10-20 |
Vib Vzw |
Nanobodies stabilizing functional conformational states of GPCRS
|
|
GB201012845D0
(en)
|
2010-07-30 |
2010-09-15 |
Vib Vzw |
Inhibition of dicer function for treatment of cancer
|
|
RU2612903C2
(ru)
|
2010-08-02 |
2017-03-13 |
Ридженерон Фармасьютикалз, Инк. |
Мыши, у которых вырабатываются связывающие белки, содержащие vl-домены
|
|
EP2606055B1
(en)
|
2010-08-16 |
2015-06-03 |
Ventana Medical Systems, Inc. |
Substrates for chromogenic detection and methods of use in detection assays and kits
|
|
JP2013535981A
(ja)
|
2010-08-20 |
2013-09-19 |
ワイス・エルエルシー |
成長因子不含適合細胞の細胞培養
|
|
PL2606070T3
(pl)
|
2010-08-20 |
2017-06-30 |
Novartis Ag |
Przeciwciała dla receptora epidermalnego czynnika wzrostu 3 (her3)
|
|
JP5964304B2
(ja)
|
2010-08-25 |
2016-08-03 |
エータイアー ファーマ, インコーポレイテッド |
チロシルtRNA合成酵素のタンパク質フラグメントに関連した治療用、診断用および抗体組成物の革新的発見
|
|
HUE036251T2
(hu)
|
2010-08-26 |
2018-06-28 |
Agrosavfe N V |
Kitinféle poliszacharid antigént kötõ fehérjék
|
|
US20130224226A1
(en)
|
2010-08-26 |
2013-08-29 |
Agrosavfe N.V. |
Insect binding antibodies
|
|
US20120225081A1
(en)
|
2010-09-03 |
2012-09-06 |
Boehringer Ingelheim International Gmbh |
Vegf-binding molecules
|
|
US20120244141A1
(en)
|
2010-09-28 |
2012-09-27 |
Boehringer Ingelheim International Gmbh |
Stratification of cancer patients for susceptibility to therapy with PTK2 inhibitors
|
|
WO2012042026A1
(en)
|
2010-09-30 |
2012-04-05 |
Ablynx Nv |
Biological materials related to c-met
|
|
JP2013543384A
(ja)
|
2010-10-05 |
2013-12-05 |
ノバルティス アーゲー |
抗−il12rベータ1抗体ならびに自己免疫性および炎症性疾患の処置おけるその使用
|
|
EP3279214B1
(en)
|
2010-10-29 |
2024-10-09 |
Ablynx NV |
Method for the production of immunoglobulin single variable domains
|
|
GB201018602D0
(en)
|
2010-11-04 |
2010-12-22 |
Vib Vzw |
MMP8 inactivating antigen binding proteins
|
|
SG189957A1
(en)
|
2010-11-05 |
2013-06-28 |
Morphotek Inc |
Folate receptor alpha as a diagnostic and prognostic marker for folate receptor alpha-expressing cancers
|
|
KR101650995B1
(ko)
|
2010-11-08 |
2016-08-25 |
노파르티스 아게 |
Cxcr2 결합 폴리펩티드
|
|
WO2012084895A2
(en)
|
2010-12-20 |
2012-06-28 |
Universiteit Gent |
Crystal structure of flt3 ligand-receptor complex
|
|
WO2012089814A1
(en)
|
2010-12-30 |
2012-07-05 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Antigen binding formats for use in therapeutic treatments or diagnostic assays
|
|
ES2593464T3
(es)
|
2010-12-30 |
2016-12-09 |
Ventana Medical Systems, Inc. |
Deposición potenciada de cromógenos utilizando análogos de pirimidina
|
|
AR085091A1
(es)
|
2011-01-26 |
2013-09-11 |
Kolltan Pharmaceuticals Inc |
Anticuerpos anti-kit y sus usos
|
|
CN103459427B
(zh)
|
2011-02-01 |
2018-03-30 |
Bac Ip私人有限公司 |
针对人IgG抗体的CH1结构域中表位的抗原结合蛋白
|
|
JP6150734B2
(ja)
|
2011-02-03 |
2017-06-21 |
アレクシオン ファーマシューティカルズ, インコーポレイテッド |
同種移植片の生存を長期化するための抗cd200抗体の使用
|
|
JP6385060B2
(ja)
|
2011-03-07 |
2018-09-05 |
エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト |
治療的に活性な抗体のインビボにおける選択
|
|
US20140099264A1
(en)
|
2011-03-07 |
2014-04-10 |
F. Hoffman-La Roche Ag |
Means and methods for in vivo testing of therapeutic antibodies
|
|
US9562259B2
(en)
|
2011-03-14 |
2017-02-07 |
Ventana Medical Systems, Inc. |
Method of analyzing chromosomal inversions
|
|
US9624294B2
(en)
|
2011-03-14 |
2017-04-18 |
Cellmid Limited |
Antibody recognizing N-domain of midkine
|
|
US20150158948A9
(en)
|
2011-03-28 |
2015-06-11 |
Francis Descamps |
Bispecific anti-cxcr7 immunoglobulin single variable domains
|
|
EP2691415B1
(en)
|
2011-03-28 |
2018-07-11 |
Ablynx N.V. |
Method for producing solid formulations comprising immunoglobulin single variable domains
|
|
WO2012131053A1
(en)
|
2011-03-30 |
2012-10-04 |
Ablynx Nv |
Methods of treating immune disorders with single domain antibodies against tnf-alpha
|
|
PH12013501924A1
(en)
|
2011-03-30 |
2017-10-25 |
Boehringer Ingelheim Int |
Anticoagulant antidotes
|
|
US9220776B2
(en)
|
2011-03-31 |
2015-12-29 |
Merck Sharp & Dohme Corp. |
Stable formulations of antibodies to human programmed death receptor PD-1 and related treatments
|
|
US9527925B2
(en)
|
2011-04-01 |
2016-12-27 |
Boehringer Ingelheim International Gmbh |
Bispecific binding molecules binding to VEGF and ANG2
|
|
US20130078247A1
(en)
|
2011-04-01 |
2013-03-28 |
Boehringer Ingelheim International Gmbh |
Bispecific binding molecules binding to dii4 and ang2
|
|
PL2699264T3
(pl)
|
2011-04-20 |
2018-08-31 |
Medimmune, Llc |
Przeciwciała i inne cząsteczki wiążące B7-H1 i PD-1
|
|
UA117218C2
(uk)
|
2011-05-05 |
2018-07-10 |
Мерк Патент Гмбх |
Поліпептид, спрямований проти il-17a, il-17f та/або il17-a/f
|
|
EP3590950A1
(en)
|
2011-05-09 |
2020-01-08 |
Ablynx NV |
Method for the production of immunoglobulin single varible domains
|
|
EP2710042A2
(en)
|
2011-05-16 |
2014-03-26 |
Fabion Pharmaceuticals, Inc. |
Multi-specific fab fusion proteins and methods of use
|
|
RU2661677C2
(ru)
|
2011-05-27 |
2018-07-18 |
Аблинкс Нв |
Ингибирование резорбции кости с помощью связывающих rank-l пептидов
|
|
US9580480B2
(en)
|
2011-05-31 |
2017-02-28 |
Massachusetts Institute Of Technology |
Cell-directed synthesis of multifunctional nanopatterns and nanomaterials
|
|
CA2838246C
(en)
|
2011-06-13 |
2018-07-10 |
Csl Limited |
Antibodies against g-csfr and uses thereof
|
|
WO2012172495A1
(en)
|
2011-06-14 |
2012-12-20 |
Novartis Ag |
Compositions and methods for antibodies targeting tem8
|
|
ES2662372T3
(es)
|
2011-06-21 |
2018-04-06 |
Vib Vzw |
Dominios de unión dirigidos contra complejos GPCR:proteína G y usos derivados de los mismos
|
|
EP2723771B1
(en)
|
2011-06-23 |
2019-09-11 |
Ablynx NV |
Serum albumin binding proteins
|
|
JP2014525736A
(ja)
|
2011-06-23 |
2014-10-02 |
アブリンクス エン.ヴェー. |
IgEに対する免疫グロブリン単一可変ドメイン
|
|
PL2726099T3
(pl)
|
2011-07-01 |
2018-12-31 |
Novartis Ag |
Sposób leczenia zaburzeń metabolicznych
|
|
GB201112056D0
(en)
|
2011-07-14 |
2011-08-31 |
Univ Leuven Kath |
Antibodies
|
|
WO2013010955A1
(en)
|
2011-07-15 |
2013-01-24 |
Morphosys Ag |
Antibodies that are cross-reactive for macrophage migration inhibitory factor (mif) and d-dopachrome tautomerase (d-dt)
|
|
PE20141522A1
(es)
|
2011-08-17 |
2014-11-17 |
Glaxo Group Ltd |
Proteinas y peptidos modificados
|
|
WO2013033073A1
(en)
|
2011-08-31 |
2013-03-07 |
Ventana Medical Systems, Inc. |
Expression of ets related gene (erg) and phosphatase and tensin homolog (pten) correlates with prostate cancer capsular penetration
|
|
GB201115529D0
(en)
|
2011-09-08 |
2011-10-26 |
Imp Innovations Ltd |
Antibodies, uses and methods
|
|
EP2753644A1
(en)
|
2011-09-09 |
2014-07-16 |
Universiteit Utrecht Holding B.V. |
Broadly neutralizing vhh against hiv-1
|
|
EP2757875B2
(en)
|
2011-09-19 |
2023-03-22 |
Kymab Limited |
Manipulation of immunoglobulin gene diversity and multi-antibody therapeutics
|
|
US20140235492A1
(en)
|
2011-09-20 |
2014-08-21 |
Institut National De La Sante Et De La Recherche Medicate (Inserm) |
Methods for preparing single domain antibody microarrays
|
|
WO2013041722A1
(en)
|
2011-09-23 |
2013-03-28 |
Ablynx Nv |
Prolonged inhibition of interleukin-6 mediated signaling
|
|
WO2013045916A1
(en)
|
2011-09-26 |
2013-04-04 |
Kymab Limited |
Chimaeric surrogate light chains (slc) comprising human vpreb
|
|
EP2747783B1
(en)
|
2011-09-30 |
2017-06-14 |
Ablynx N.V. |
Biological materials related to c-met
|
|
US20130085139A1
(en)
|
2011-10-04 |
2013-04-04 |
Royal Holloway And Bedford New College |
Oligomers
|
|
JP2014530816A
(ja)
|
2011-10-14 |
2014-11-20 |
ノバルティスアーゲー |
Wnt経路関連疾患のための抗体および方法
|
|
US9127056B2
(en)
|
2011-10-17 |
2015-09-08 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Monospecific and bispecific human monoclonal antibodies targeting insulin-like growth factor II (IGF-II)
|
|
AU2012327878A1
(en)
|
2011-10-28 |
2014-05-29 |
Patrys Limited |
PAT-LM1 epitopes and methods for using same
|
|
GB2496375A
(en)
|
2011-10-28 |
2013-05-15 |
Kymab Ltd |
A non-human assay vertebrate comprising human antibody loci and human epitope knock-in, and uses thereof
|
|
SG11201401649VA
(en)
|
2011-11-11 |
2014-07-30 |
Ucb Pharma Sa |
Albumin binding antibodies and binding fragments thereof
|
|
WO2013079606A1
(en)
|
2011-12-01 |
2013-06-06 |
Ventana Medical Systems, Inc. |
Automated dual stain of mirna and protein targets
|
|
GB201122047D0
(en)
|
2011-12-21 |
2012-02-01 |
Kymab Ltd |
Transgenic animals
|
|
EP2785741A1
(en)
|
2011-12-02 |
2014-10-08 |
Cancer Research Technology Limited |
Antibodies against hgf - receptor and uses
|
|
EP2788382A2
(en)
|
2011-12-05 |
2014-10-15 |
Novartis AG |
Antibodies for epidermal growth factor receptor 3 (her3) directed to domain ii of her3
|
|
AU2012349735B2
(en)
|
2011-12-05 |
2016-05-19 |
Novartis Ag |
Antibodies for epidermal growth factor receptor 3 (HER3)
|
|
CA2859493A1
(en)
|
2011-12-21 |
2013-06-27 |
Novartis Ag |
Compositions and methods for antibodies targeting factor p
|
|
US10112988B2
(en)
|
2012-01-09 |
2018-10-30 |
Icb International, Inc. |
Methods of assessing amyloid-beta peptides in the central nervous system by blood-brain barrier permeable peptide compositions comprising a vab domain of a camelid single domain heavy chain antibody against an anti-amyloid-beta peptide
|
|
US10112987B2
(en)
|
2012-01-09 |
2018-10-30 |
Icb International, Inc. |
Blood-brain barrier permeable peptide compositions comprising a vab domain of a camelid single domain heavy chain antibody against an amyloid-beta peptide
|
|
WO2013108126A2
(en)
|
2012-01-16 |
2013-07-25 |
University Of Oslo |
Methyltransferases and uses thereof
|
|
CA2862222A1
(en)
|
2012-01-20 |
2013-07-25 |
Genzyme Corporation |
Anti-cxcr3 antibodies
|
|
US20150301068A1
(en)
|
2012-01-30 |
2015-10-22 |
Vib Vzw |
Means and method for diagnosis and treatment of alzheimer's disease
|
|
WO2013121042A1
(en)
|
2012-02-16 |
2013-08-22 |
Vib Vzw |
PP2A SUBUNITS IN DNA REPAIR, THE PP2A B55α SUBUNIT AS NOVEL PHD2 INTERACTING PROTEIN, AND IMPLICATIONS FOR CANCER
|
|
UA115781C2
(uk)
|
2012-02-27 |
2017-12-26 |
Бьорінгер Інгельхайм Інтернаціональ Гмбх |
Cx3cr1-зв'язуючий поліпептид
|
|
US9592289B2
(en)
|
2012-03-26 |
2017-03-14 |
Sanofi |
Stable IgG4 based binding agent formulations
|
|
WO2013148498A1
(en)
|
2012-03-27 |
2013-10-03 |
Ventana Medical Systems, Inc. |
Signaling conjugates and methods of use
|
|
CA2865464C
(en)
|
2012-03-30 |
2022-07-12 |
Boehringer Ingelheim International Gmbh |
Ang2-binding molecules
|
|
US9156915B2
(en)
|
2012-04-26 |
2015-10-13 |
Thomas Jefferson University |
Anti-GCC antibody molecules
|
|
US9328174B2
(en)
|
2012-05-09 |
2016-05-03 |
Novartis Ag |
Chemokine receptor binding polypeptides
|
|
CA2874309C
(en)
|
2012-05-24 |
2021-06-15 |
Vib Vzw |
Anti-macrophage mannose receptor single variable domains for targeting and in vivo imaging of tumor-associated macrophages
|
|
EP2687595B1
(en)
|
2012-07-19 |
2018-05-30 |
Laboratoire Français du Fractionnement et des Biotechnologies |
Method for purifying transgenic factor VII
|
|
SG11201500489YA
(en)
|
2012-07-25 |
2015-02-27 |
Kolltan Pharmaceuticals Inc |
Anti-kit antibodies and uses thereof
|
|
WO2014018535A1
(en)
|
2012-07-25 |
2014-01-30 |
Salk Institute For Biological Studies |
Regulating the interaction between tam ligands and lipid membranes with exposed phosphatidylserine
|
|
EP2890720B1
(en)
|
2012-08-30 |
2019-07-17 |
The General Hospital Corporation |
Compositions and methods for treating cancer
|
|
UA118441C2
(uk)
|
2012-10-08 |
2019-01-25 |
Протена Біосаєнсиз Лімітед |
Антитіло, що розпізнає альфа-синуклеїн
|
|
HK1213794A1
(zh)
|
2012-10-09 |
2016-07-15 |
Biogen Ma Inc. |
联合治疗及用於治疗脱髓鞘病症的用途
|
|
BR112015011061B1
(pt)
|
2012-11-20 |
2022-09-27 |
Novartis Ag |
Cassete de expressão adequado para expressão de um polipeptídeo de interesse, vetor de expressão, métodos para produzir uma célula hospedeira eucariótica e um polipeptídeo de interesse, e uso de uma sequência 5'utr em combinação com uma sequência líder de secreção de hcd33 em um cassete de expressão
|
|
WO2014084859A1
(en)
|
2012-11-30 |
2014-06-05 |
Novartis Ag |
Molecules and methods for modulating tmem16a activities
|
|
HRP20210517T1
(hr)
|
2012-12-05 |
2021-05-14 |
Novartis Ag |
Pripravci i postupci za protutijela usmjerena na epo
|
|
WO2014087010A1
(en)
|
2012-12-07 |
2014-06-12 |
Ablynx N.V. |
IMPROVED POLYPEPTIDES DIRECTED AGAINST IgE
|
|
PT2931030T
(pt)
|
2012-12-14 |
2020-08-03 |
Open Monoclonal Tech Inc |
Polinucleótidos que codificam anticorpos de roedores com idiótipos humanos e animais que os compreendem
|
|
KR20150095684A
(ko)
|
2012-12-18 |
2015-08-21 |
노파르티스 아게 |
히알루로난에 결합하는 펩티드 태그를 이용하는 조성물 및 방법
|
|
EP2934575A2
(en)
|
2012-12-19 |
2015-10-28 |
Amplimmune, Inc. |
B7-h4 specific antibodies, and compositions and methods of use thereof
|
|
AU2013204922B2
(en)
|
2012-12-20 |
2015-05-14 |
Celgene Corporation |
Chimeric antigen receptors
|
|
AR093984A1
(es)
|
2012-12-21 |
2015-07-01 |
Merck Sharp & Dohme |
Anticuerpos que se unen a ligando 1 de muerte programada (pd-l1) humano
|
|
MX2015008117A
(es)
|
2012-12-21 |
2016-03-31 |
Amplimmune Inc |
Anticuerpos anti-h7cr.
|
|
CN105102478A
(zh)
|
2013-01-30 |
2015-11-25 |
弗拉芒区生物技术研究所 |
用于筛选和药物发现目的的新型嵌合多肽
|
|
WO2014120916A1
(en)
|
2013-02-01 |
2014-08-07 |
Bristol-Myers Squibb Company |
Pegylated domain antibodies monovalent for cd28 binding and methods of use
|
|
EP3590578A1
(en)
|
2013-02-05 |
2020-01-08 |
VIB vzw |
Muscarinic acetylcholine receptor binding agents and uses thereof
|
|
EP2953971B1
(en)
|
2013-02-07 |
2023-03-01 |
CSL Limited |
Il-11r binding proteins and uses thereof
|
|
AP2015008584A0
(en)
|
2013-02-08 |
2015-07-31 |
Novartis Ag |
Anti-il-17a antibodies and their use in treating autoimmune and inflammatory disorders
|
|
RU2015140915A
(ru)
|
2013-02-26 |
2017-04-03 |
Роше Гликарт Аг |
Биспецифические антигенсвязывающие молекулы, активирующие т-клетки
|
|
EP2962100B1
(en)
|
2013-02-28 |
2021-07-28 |
Caprion Proteomics Inc. |
Tuberculosis biomarkers and uses thereof
|
|
EP3764084A1
(en)
|
2013-03-12 |
2021-01-13 |
Ventana Medical Systems, Inc. |
Digitally enhanced microscopy for multiplexed histology
|
|
JP6674888B2
(ja)
|
2013-03-13 |
2020-04-01 |
プロセナ バイオサイエンシーズ リミテッド |
タウ免疫療法
|
|
WO2014159239A2
(en)
|
2013-03-14 |
2014-10-02 |
Novartis Ag |
Antibodies against notch 3
|
|
CA2906259C
(en)
|
2013-03-15 |
2022-12-06 |
Vib Vzw |
Anti-mmr single variable domains for prognosis and monitoring of cardiovascular diseases
|
|
EP4079760A3
(en)
|
2013-03-15 |
2023-01-25 |
Sanofi Pasteur Inc. |
Antibodies against clostridium difficile toxins and methods of using the same
|
|
CN105518018B
(zh)
|
2013-03-15 |
2020-04-03 |
细胞基因公司 |
修饰的t淋巴细胞
|
|
EP2970426B1
(en)
|
2013-03-15 |
2019-08-28 |
Michael C. Milone |
Targeting cytotoxic cells with chimeric receptors for adoptive immunotherapy
|
|
WO2014141192A1
(en)
|
2013-03-15 |
2014-09-18 |
Erasmus University Medical Center |
Generation of heavy chain-only antibodies
|
|
JP6574754B2
(ja)
|
2013-03-19 |
2019-09-11 |
ベイジン シェノゲン ファーマ グループ リミテッド |
エストロゲン受容体関連疾患を処置するための抗体及び方法
|
|
PL2992101T3
(pl)
|
2013-04-29 |
2019-05-31 |
Agrosavfe Nv |
Kompozycje agrochemiczne zawierające przeciwciała wiążące się ze sfingolipidami
|
|
AR096236A1
(es)
|
2013-05-09 |
2015-12-16 |
The Us Secretary Dept Of Health And Human Services Nat Inst Of Health Office Of Tech Transfer |
Anticuerpos de dominio simple vhh dirigidos a norovirus gi.1 y gii.4 y sus usos
|
|
NL1040254C2
(en)
|
2013-05-17 |
2014-11-24 |
Ablynx Nv |
Stable formulations of immunoglobulin single variable domains and uses thereof.
|
|
JP6682426B2
(ja)
|
2013-05-24 |
2020-04-15 |
メディミューン,エルエルシー |
抗b7−h5抗体およびその使用
|
|
WO2014194293A1
(en)
|
2013-05-30 |
2014-12-04 |
Amplimmune, Inc. |
Improved methods for the selection of patients for pd-1 or b7-h4 targeted therapies, and combination therapies thereof
|
|
SG11201509982UA
(da)
|
2013-06-06 |
2016-04-28 |
Igenica Biotherapeutics Inc |
|
|
AR096601A1
(es)
|
2013-06-21 |
2016-01-20 |
Novartis Ag |
Anticuerpos del receptor 1 de ldl oxidado similar a lectina y métodos de uso
|
|
US9562101B2
(en)
|
2013-06-21 |
2017-02-07 |
Novartis Ag |
Lectin-like oxidized LDL receptor 1 antibodies and methods of use
|
|
EP3013356B1
(en)
|
2013-06-27 |
2018-10-17 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Interleukin 15 (il-15) antagonists and uses thereof for the treatment of autoimmune diseases and inflammatory diseases
|
|
EP3016973A1
(en)
|
2013-07-05 |
2016-05-11 |
INSERM - Institut National de la Santé et de la Recherche Médicale |
Novel alternative splice transcripts for mhc class i related chain alpha (mica) and uses thereof
|
|
US9951131B2
(en)
|
2013-07-12 |
2018-04-24 |
Prothena Biosciences Limited |
Antibodies that recognize IAPP
|
|
US9850302B2
(en)
|
2013-07-12 |
2017-12-26 |
Prothena Biosciences Limited |
Antibodies that recognize IAPP
|
|
AU2014306002B2
(en)
|
2013-08-07 |
2017-05-25 |
Alexion Pharmaceuticals, Inc. |
Atypical hemolytic uremic syndrome (aHUS) biomarker proteins
|
|
TW201536318A
(zh)
|
2013-08-14 |
2015-10-01 |
Novartis Ag |
治療偶發性包涵體肌炎之方法
|
|
AR097306A1
(es)
|
2013-08-20 |
2016-03-02 |
Merck Sharp & Dohme |
Modulación de la inmunidad tumoral
|
|
DK3074038T3
(da)
|
2013-11-28 |
2019-03-11 |
Csl Ltd |
Fremgangsmåde til behandling af diabetisk nephropati
|
|
EP2883883A1
(en)
|
2013-12-16 |
2015-06-17 |
Cardio3 Biosciences S.A. |
Therapeutic targets and agents useful in treating ischemia reperfusion injury
|
|
JP6553618B2
(ja)
|
2013-12-18 |
2019-07-31 |
シーエスエル リミティド |
創傷を治療する方法
|
|
CA3225453A1
(en)
|
2013-12-19 |
2015-06-25 |
Novartis Ag |
Human mesothelin chimeric antigen receptors and uses thereof
|
|
EP3087101B1
(en)
|
2013-12-20 |
2024-06-05 |
Novartis AG |
Regulatable chimeric antigen receptor
|
|
CA2932515C
(en)
|
2013-12-20 |
2023-08-01 |
Intervet International B.V. |
Caninized antibodies
|
|
WO2015100409A2
(en)
|
2013-12-26 |
2015-07-02 |
Tufts University |
Methods, compositions and kits for treating a subject using a recombinant neutralizing binding protein
|
|
JOP20200094A1
(ar)
|
2014-01-24 |
2017-06-16 |
Dana Farber Cancer Inst Inc |
جزيئات جسم مضاد لـ pd-1 واستخداماتها
|
|
WO2015121092A1
(en)
|
2014-01-30 |
2015-08-20 |
Vib Vzw |
Opioid receptor binding agents and uses thereof
|
|
JOP20200096A1
(ar)
|
2014-01-31 |
2017-06-16 |
Children’S Medical Center Corp |
جزيئات جسم مضاد لـ tim-3 واستخداماتها
|
|
CN106211773B
(zh)
|
2014-02-11 |
2021-09-03 |
威特拉公司 |
用于登革病毒的抗体分子及其应用
|
|
JP2017506640A
(ja)
|
2014-02-14 |
2017-03-09 |
セントローズ, エルエルシー |
細胞外標的化薬物共役体
|
|
GB201403775D0
(en)
|
2014-03-04 |
2014-04-16 |
Kymab Ltd |
Antibodies, uses & methods
|
|
NZ631007A
(en)
|
2014-03-07 |
2015-10-30 |
Alexion Pharma Inc |
Anti-c5 antibodies having improved pharmacokinetics
|
|
ME03558B
(me)
|
2014-03-14 |
2020-07-20 |
Novartis Ag |
Molekuli anti-lag-3 antiтela i njihove upotrebe
|
|
WO2015142675A2
(en)
|
2014-03-15 |
2015-09-24 |
Novartis Ag |
Treatment of cancer using chimeric antigen receptor
|
|
ES2857226T3
(es)
|
2014-03-15 |
2021-09-28 |
Novartis Ag |
Receptor de antígeno quimérico regulable
|
|
WO2015143406A2
(en)
|
2014-03-21 |
2015-09-24 |
Regeneron Pharmaceuticals, Inc. |
Vl antigen binding proteins exhibiting distinct binding characteristics
|
|
RU2016141307A
(ru)
|
2014-03-21 |
2018-04-24 |
Регенерон Фармасьютикалз, Инк. |
Отличные от человека животные, которые вырабатывают однодоменные связывающие белки
|
|
WO2015155694A1
(en)
|
2014-04-08 |
2015-10-15 |
Prothena Biosciences Limited |
Blood-brain barrier shuttles containing antibodies recognizing alpha-synuclein
|
|
TW201622746A
(zh)
|
2014-04-24 |
2016-07-01 |
諾華公司 |
改善或加速髖部骨折術後身體復原之方法
|
|
SI3689899T1
(sl)
|
2014-04-25 |
2022-01-31 |
2Seventy Bio, Inc. |
MND promotor kimeričnih antigenskih receptorjev
|
|
EP3738597A1
(en)
|
2014-04-25 |
2020-11-18 |
Bluebird Bio, Inc. |
Improved methods for manufacturing adoptive cell therapies
|
|
US9388239B2
(en)
|
2014-05-01 |
2016-07-12 |
Consejo Nacional De Investigation Cientifica |
Anti-human VEGF antibodies with unusually strong binding affinity to human VEGF-A and cross reactivity to human VEGF-B
|
|
KR20250099289A
(ko)
|
2014-05-16 |
2025-07-01 |
아블린쓰 엔.브이. |
개선된 면역글로불린 가변 도메인
|
|
PT3248986T
(pt)
|
2014-05-16 |
2022-04-05 |
Ablynx Nv |
Domínios variáveis de imunoglobulina
|
|
SMT202100116T1
(it)
|
2014-05-28 |
2021-05-07 |
Agenus Inc |
Anticorpi anti-gitr e metodi di utilizzo degli stessi
|
|
NZ726989A
(en)
|
2014-06-06 |
2020-08-28 |
Bluebird Bio Inc |
Improved t cell compositions
|
|
NL2013007B1
(en)
|
2014-06-16 |
2016-07-05 |
Ablynx Nv |
Methods of treating TTP with immunoglobulin single variable domains and uses thereof.
|
|
NL2013661B1
(en)
|
2014-10-21 |
2016-10-05 |
Ablynx Nv |
KV1.3 Binding immunoglobulins.
|
|
WO2015198240A2
(en)
|
2014-06-25 |
2015-12-30 |
Novartis Ag |
Compositions and methods for long acting proteins
|
|
US20170290876A1
(en)
|
2014-06-25 |
2017-10-12 |
Novartis Ag |
Compositions and methods for long acting proteins
|
|
US20170291939A1
(en)
|
2014-06-25 |
2017-10-12 |
Novartis Ag |
Antibodies specific for il-17a fused to hyaluronan binding peptide tags
|
|
JP2017528433A
(ja)
|
2014-07-21 |
2017-09-28 |
ノバルティス アーゲー |
低い免疫増強用量のmTOR阻害剤とCARの組み合わせ
|
|
WO2016014565A2
(en)
|
2014-07-21 |
2016-01-28 |
Novartis Ag |
Treatment of cancer using humanized anti-bcma chimeric antigen receptor
|
|
WO2016014553A1
(en)
|
2014-07-21 |
2016-01-28 |
Novartis Ag |
Sortase synthesized chimeric antigen receptors
|
|
BR112017001242A2
(pt)
|
2014-07-21 |
2017-12-05 |
Novartis Ag |
tratamento de câncer usando um receptor antigênico quimérico a cd33
|
|
CA2955554C
(en)
|
2014-07-22 |
2022-07-05 |
Vib Vzw |
Methods to select for agents that stabilize protein complexes
|
|
SG10201900455YA
(en)
|
2014-07-24 |
2019-02-27 |
Bluebird Bio Inc |
Bcma chimeric antigen receptors
|
|
WO2016016329A1
(en)
|
2014-07-29 |
2016-02-04 |
Vrije Universiteit Brussel |
Radio-labelled antibody fragments for use in the prognosis, diagnosis of cancer as well as for the prediction of cancer therapy response
|
|
CN106573983B
(zh)
|
2014-07-29 |
2018-05-25 |
布鲁塞尔自由大学 |
用于在癌症的预防和/或治疗中使用的放射性标记的抗体片段
|
|
US20170209492A1
(en)
|
2014-07-31 |
2017-07-27 |
Novartis Ag |
Subset-optimized chimeric antigen receptor-containing t-cells
|
|
WO2016020882A2
(en)
|
2014-08-07 |
2016-02-11 |
Novartis Ag |
Angiopoetin-like 4 (angptl4) antibodies and methods of use
|
|
SG10201805646WA
(en)
|
2014-08-07 |
2018-08-30 |
Novartis Ag |
Angiopoietin-like 4 antibodies and methods of use
|
|
JP6919118B2
(ja)
|
2014-08-14 |
2021-08-18 |
ノバルティス アーゲー |
GFRα−4キメラ抗原受容体を用いる癌の治療
|
|
KR102050082B1
(ko)
|
2014-08-19 |
2019-11-29 |
머크 샤프 앤드 돔 코포레이션 |
항-tigit 항체
|
|
JO3663B1
(ar)
|
2014-08-19 |
2020-08-27 |
Merck Sharp & Dohme |
الأجسام المضادة لمضاد lag3 وأجزاء ربط الأنتيجين
|
|
MY189028A
(en)
|
2014-08-19 |
2022-01-20 |
Novartis Ag |
Anti-cd123 chimeric antigen receptor (car) for use in cancer treatment
|
|
KR20170060042A
(ko)
|
2014-09-13 |
2017-05-31 |
노파르티스 아게 |
Alk 억제제의 조합 요법
|
|
CA2961636A1
(en)
|
2014-09-17 |
2016-03-24 |
Boris ENGELS |
Targeting cytotoxic cells with chimeric receptors for adoptive immunotherapy
|
|
EA201790737A1
(ru)
|
2014-10-03 |
2017-08-31 |
Новартис Аг |
Комбинированная терапия
|
|
KR20230042391A
(ko)
|
2014-10-03 |
2023-03-28 |
나노틱스 엘엘씨 |
가용성 생물분자의 생물학적 활성을 억제하기 위한 조성물 및 방법
|
|
MA41044A
(fr)
|
2014-10-08 |
2017-08-15 |
Novartis Ag |
Compositions et procédés d'utilisation pour une réponse immunitaire accrue et traitement contre le cancer
|
|
RU2017115670A
(ru)
|
2014-10-10 |
2018-11-15 |
Аблинкс Н.В. |
Лечение инфекции рсв
|
|
SI3204095T1
(sl)
|
2014-10-10 |
2019-08-30 |
Ablynx N.V. |
Inhalacijska naprava za uporabo pri zdravljenju bolezni dihal z aerosolom
|
|
MX389663B
(es)
|
2014-10-14 |
2025-03-20 |
Novartis Ag |
Moleculas de anticuerpo que se unen a pd-l1 y usos de las mismas.
|
|
WO2016061632A1
(en)
|
2014-10-23 |
2016-04-28 |
La Trobe University |
Fn14-binding proteins and uses thereof
|
|
BR112017009330A2
(pt)
|
2014-11-05 |
2017-12-19 |
Agrosavfe N V |
planta transgênica que compreende um polinucleotídeo que codifica um domínio variável de anticorpo de cadeia pesada
|
|
US20180334490A1
(en)
|
2014-12-03 |
2018-11-22 |
Qilong H. Wu |
Methods for b cell preconditioning in car therapy
|
|
US11001625B2
(en)
|
2014-12-10 |
2021-05-11 |
Tufts University |
VHH based binding antibodies for anthrax and botulinum toxins and methods of making and using therefor
|
|
EP3333191B1
(en)
|
2014-12-11 |
2020-09-09 |
Pierre Fabre Médicament |
Anti-c10orf54 antibodies and uses thereof
|
|
NZ733025A
(en)
|
2014-12-12 |
2022-01-28 |
2Seventy Bio Inc |
Bcma chimeric antigen receptors
|
|
WO2016094834A2
(en)
|
2014-12-12 |
2016-06-16 |
Alexion Pharmaceuticals, Inc. |
A method for treating a complement mediated disorder caused by an infectious agent in a patient
|
|
JP6862343B2
(ja)
|
2014-12-19 |
2021-04-21 |
アブリンクス エン.ヴェー. |
システイン結合ナノボディダイマー
|
|
WO2016100882A1
(en)
|
2014-12-19 |
2016-06-23 |
Novartis Ag |
Combination therapies
|
|
UY36449A
(es)
|
2014-12-19 |
2016-07-29 |
Novartis Ag |
Composiciones y métodos para anticuerpos dirigidos a bmp6
|
|
AU2015367224B2
(en)
|
2014-12-19 |
2020-12-10 |
Monash University |
IL-21 antibodies
|
|
WO2016106221A1
(en)
|
2014-12-22 |
2016-06-30 |
The Rockefeller University |
Anti-mertk agonistic antibodies and uses thereof
|
|
IL303247A
(en)
|
2014-12-29 |
2023-07-01 |
Novartis Ag |
Methods for preparing cells expressing a chimeric receptor antigen
|
|
EP3240569A4
(en)
|
2014-12-30 |
2018-05-30 |
Celgene Corporation |
Anti-cd47 antibodies and uses thereof
|
|
CA2972757A1
(en)
|
2014-12-31 |
2016-07-07 |
Arthur M. Krieg |
Combination tumor immunotherapy
|
|
AU2016205197B2
(en)
|
2015-01-08 |
2021-10-21 |
Biogen Ma Inc. |
LINGO-1 antagonists and uses for treatment of demyelinating disorders
|
|
GB201501004D0
(en)
|
2015-01-21 |
2015-03-04 |
Cancer Rec Tech Ltd |
Inhibitors
|
|
WO2016126608A1
(en)
|
2015-02-02 |
2016-08-11 |
Novartis Ag |
Car-expressing cells against multiple tumor antigens and uses thereof
|
|
ES2791950T3
(es)
|
2015-02-03 |
2020-11-06 |
Ventana Med Syst Inc |
Ensayo histoquímico para evaluar la expresión del ligando de muerte programada 1 (PD-L1)
|
|
WO2016124568A1
(en)
|
2015-02-03 |
2016-08-11 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Anti-rho gtpase conformational single domain antibodies and uses thereof
|
|
WO2016128549A1
(en)
|
2015-02-13 |
2016-08-18 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Polypeptides for engineering integrase chimeric proteins and their use in gene therapy
|
|
WO2016138160A1
(en)
|
2015-02-24 |
2016-09-01 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Middle east respiratory syndrome coronavirus immunogens, antibodies, and their use
|
|
WO2016135041A1
(en)
|
2015-02-26 |
2016-09-01 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Fusion proteins and antibodies comprising thereof for promoting apoptosis
|
|
EP3061826A1
(en)
|
2015-02-27 |
2016-08-31 |
Novartis AG |
Flavivirus replicons
|
|
ES2937020T3
(es)
|
2015-03-03 |
2023-03-23 |
Kymab Ltd |
Anticuerpos, usos y métodos
|
|
MX391249B
(es)
|
2015-03-17 |
2025-03-21 |
Memorial Sloan Kettering Cancer Center |
Anticuerpos anti-muc16 y sus usos.
|
|
MA41795A
(fr)
|
2015-03-18 |
2018-01-23 |
Sarepta Therapeutics Inc |
Exclusion d'un exon induite par des composés antisens dans la myostatine
|
|
US11111314B2
(en)
|
2015-03-19 |
2021-09-07 |
Regeneron Pharmaceuticals, Inc. |
Non-human animals that select for light chain variable regions that bind antigen
|
|
ES2721781T3
(es)
|
2015-03-25 |
2019-08-05 |
Alexion Pharma Inc |
Un método para medir la actividad proteasa de C3 y C5 convertasa de la vía de complemento alternativa
|
|
WO2016151558A1
(en)
|
2015-03-25 |
2016-09-29 |
Alexion Pharmaceuticals, Inc. |
A method for measuring the protease activity of factor d of the alternative complement pathway
|
|
HK1250040A1
(zh)
|
2015-03-31 |
2018-11-23 |
Sorriso Pharmaceuticals, Inc. |
多肽
|
|
CA2981098A1
(en)
|
2015-03-31 |
2016-10-06 |
Vhsquared Limited |
Peptide construct having a protease-cleavable linker
|
|
JP6895421B2
(ja)
|
2015-03-31 |
2021-06-30 |
ブイエイチスクエアード リミテッド |
ポリペプチド
|
|
WO2016156588A1
(en)
|
2015-04-02 |
2016-10-06 |
Intervet International B.V. |
Antibodies to canine interleukin-4 receptor alpha
|
|
ES3029413T3
(en)
|
2015-04-02 |
2025-06-24 |
Ablynx Nv |
Bispecific cxcr4-cd-4 polypeptides with potent anti-hiv activity
|
|
ES2876974T3
(es)
|
2015-04-07 |
2021-11-15 |
Novartis Ag |
Combinación de terapia con receptor de antígeno quimérico y derivados de amino pirimidina
|
|
EP3283108B1
(en)
|
2015-04-13 |
2020-10-14 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical compositions for treatment of haemorrhagic diseases
|
|
US9778265B2
(en)
|
2015-04-16 |
2017-10-03 |
The United States Of America, As Represented By The Secretary Of The Navy |
Charged peptide appendage to facilitate oriented protein covalent immobilization
|
|
US20180112006A1
(en)
|
2015-04-17 |
2018-04-26 |
The General Hospital Corporation |
Agents, systems and methods for treating cancer
|
|
CN108473957B
(zh)
|
2015-04-17 |
2024-07-16 |
诺华股份有限公司 |
改善嵌合抗原受体表达细胞的功效和扩增的方法
|
|
WO2016172583A1
(en)
|
2015-04-23 |
2016-10-27 |
Novartis Ag |
Treatment of cancer using chimeric antigen receptor and protein kinase a blocker
|
|
TWI716405B
(zh)
|
2015-05-07 |
2021-01-21 |
美商艾吉納斯公司 |
抗ox40抗體及其使用方法
|
|
EP3294334B1
(en)
|
2015-05-11 |
2020-07-08 |
The Johns Hopkins University |
Autoimmune antibodies for use in inhibiting cancer cell growth
|
|
SI3294319T1
(sl)
|
2015-05-13 |
2024-09-30 |
Ablynx Nv |
Polipeptidi, ki rekrutirajo celice T na osnovi reaktivnosti CD3
|
|
EP3611192B1
(en)
|
2015-05-13 |
2025-03-05 |
Ablynx N.V. |
T cell recruiting polypeptides based on tcr alpha/beta reactivity
|
|
CN111234027A
(zh)
|
2015-05-21 |
2020-06-05 |
哈普恩治疗公司 |
三特异性结合蛋白质及使用方法
|
|
WO2016191659A1
(en)
|
2015-05-28 |
2016-12-01 |
Bio-Rad Laboratories, Inc. |
Affinity ligands and methods relating thereto
|
|
CN107849144B
(zh)
|
2015-05-29 |
2021-09-17 |
艾吉纳斯公司 |
抗-ctla-4抗体及其使用方法
|
|
CA2982237A1
(en)
|
2015-06-05 |
2016-12-08 |
Novartis Ag |
Antibodies targeting bone morphogenetic protein 9 (bmp9) and methods therefor
|
|
EP3307777A4
(en)
|
2015-06-11 |
2019-02-13 |
Wuxi Biologics (Shanghai) Co. Ltd. |
NOVEL ANTI-PD-L1 ANTIBODIES
|
|
WO2016207313A1
(en)
|
2015-06-24 |
2016-12-29 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and kits for detecting protein-protein interactions
|
|
JOP20200312A1
(ar)
|
2015-06-26 |
2017-06-16 |
Novartis Ag |
الأجسام المضادة للعامل xi وطرق الاستخدام
|
|
MX390949B
(es)
|
2015-07-17 |
2025-03-21 |
Univ Brussel Vrije |
Fragmentos de anticuerpos radiomarcados para uso en tratamiento de cancer.
|
|
JP7146632B2
(ja)
|
2015-07-21 |
2022-10-04 |
ノバルティス アーゲー |
免疫細胞の有効性および増大を改善する方法
|
|
EP3878465A1
(en)
|
2015-07-29 |
2021-09-15 |
Novartis AG |
Combination therapies comprising antibody molecules to tim-3
|
|
DK3317301T3
(da)
|
2015-07-29 |
2021-06-28 |
Immutep Sas |
Kombinationsterapier omfattende antistofmolekyler mod lag-3
|
|
US20180222982A1
(en)
|
2015-07-29 |
2018-08-09 |
Novartis Ag |
Combination therapies comprising antibody molecules to pd-1
|
|
EP3328393B1
(en)
|
2015-07-31 |
2023-12-20 |
Centrose, Llc |
Extracellular drug conjugates targeting cd20
|
|
GB2557123B
(en)
|
2015-07-31 |
2021-11-03 |
Univ Minnesota |
Modified cells and methods of therapy
|
|
KR102728071B1
(ko)
|
2015-08-03 |
2024-11-11 |
노파르티스 아게 |
Fgf21-연관 장애를 치료하는 방법
|
|
WO2017020291A1
(en)
|
2015-08-06 |
2017-02-09 |
Wuxi Biologics (Shanghai) Co. Ltd. |
Novel anti-pd-l1 antibodies
|
|
ES2855998T3
(es)
|
2015-08-07 |
2021-09-27 |
Merck Patent Gmbh |
Etiqueta transglutamina para bioconjugación específica de sitio eficiente
|
|
CN105384825B
(zh)
|
2015-08-11 |
2018-06-01 |
南京传奇生物科技有限公司 |
一种基于单域抗体的双特异性嵌合抗原受体及其应用
|
|
FI3334763T3
(fi)
|
2015-08-11 |
2024-10-30 |
Wuxi Biologics Ireland Ltd |
Uusia pd-l1-vasta-aineita
|
|
ES2911015T3
(es)
|
2015-08-31 |
2022-05-17 |
Helixmith Co Ltd |
Receptores quiméricos de antígeno anti-sialil Tn
|
|
HK1257840A1
(zh)
|
2015-09-01 |
2019-11-01 |
Agenus Inc. |
抗-pd-1抗体及其使用方法
|
|
US11747346B2
(en)
|
2015-09-03 |
2023-09-05 |
Novartis Ag |
Biomarkers predictive of cytokine release syndrome
|
|
MY186352A
(en)
|
2015-09-09 |
2021-07-15 |
Novartis Ag |
Thymic stromal lymphopoietin (tslp)-binding antibodies and methods of using the antibodies
|
|
RS61763B1
(sr)
|
2015-09-09 |
2021-05-31 |
Novartis Ag |
Antitela koja vezuju timusni stromalni limfopoetin (tslp) i metode za korišćenje antitela
|
|
WO2017053469A2
(en)
|
2015-09-21 |
2017-03-30 |
Aptevo Research And Development Llc |
Cd3 binding polypeptides
|
|
JP2018530574A
(ja)
|
2015-10-07 |
2018-10-18 |
アレクシオン ファーマシューティカルズ, インコーポレイテッド |
患者の加齢黄斑変性を治療する方法
|
|
MA45819A
(fr)
|
2015-10-09 |
2018-08-15 |
Sarepta Therapeutics Inc |
Compositions et méthodes pour traiter la dystrophie musculaire de duchenne et troubles associés
|
|
CN105238759B
(zh)
*
|
2015-10-14 |
2019-05-24 |
吉日木图 |
抗驼乳重链IgG3单克隆抗体、含有所述单克隆抗体的试纸及其应用
|
|
WO2017083515A2
(en)
|
2015-11-10 |
2017-05-18 |
Visterra, Inc. |
Antibody molecule-drug conjugates and uses thereof
|
|
NO2768984T3
(da)
|
2015-11-12 |
2018-06-09 |
|
|
|
US20180327499A1
(en)
|
2015-11-13 |
2018-11-15 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Anti- nkg2d single domain antibodies and uses thereof
|
|
SG10201911035QA
(en)
|
2015-11-18 |
2020-01-30 |
Merck Sharp & Dohme |
Pd1 and/or lag3 binders
|
|
HK1254952A1
(zh)
|
2015-11-18 |
2019-08-02 |
Merck Sharp & Dohme Llc |
Ctla4结合剂
|
|
HRP20231578T1
(hr)
|
2015-11-25 |
2024-03-15 |
Visterra, Inc. |
Molekule protutijela na april i njihove uporabe
|
|
CA3006398A1
(en)
|
2015-11-27 |
2017-06-01 |
Ablynx Nv |
Polypeptides inhibiting cd40l
|
|
SG10201912051TA
(en)
|
2015-11-27 |
2020-02-27 |
Csl Ltd |
Cd131 binding proteins and uses thereof
|
|
MA54648A
(fr)
|
2015-12-04 |
2021-11-10 |
Boehringer Ingelheim Int |
Polypeptides biparatopiques antagonistes de la signalisation wnt dans des cellules tumorales
|
|
US11479755B2
(en)
|
2015-12-07 |
2022-10-25 |
2Seventy Bio, Inc. |
T cell compositions
|
|
WO2017097889A1
(en)
|
2015-12-10 |
2017-06-15 |
Katholieke Universiteit Leuven |
Anti adamts13 antibodies and their use for treatment or prevention of haemorrhagic disorders due to ventricular assist device
|
|
MX2018007406A
(es)
|
2015-12-16 |
2018-08-15 |
Merck Sharp & Dohme |
Anticuerpos anti-lag3 y fragmentos de enlace al antigeno.
|
|
JP2019502695A
(ja)
|
2015-12-17 |
2019-01-31 |
ノバルティス アーゲー |
PD−1に対する抗体分子とC−Met阻害剤との組合せおよびその使用
|
|
EP3389712B1
(en)
|
2015-12-17 |
2024-04-10 |
Novartis AG |
Antibody molecules to pd-1 and uses thereof
|
|
JP7008020B2
(ja)
|
2015-12-18 |
2022-01-25 |
インターベット インターナショナル ベー. フェー. |
ヒトおよびイヌil-4rアルファに対するイヌ化ヒト抗体
|
|
US11091556B2
(en)
|
2015-12-18 |
2021-08-17 |
Intervet Inc. |
Caninized human antibodies to human IL-4R alpha
|
|
UY37030A
(es)
|
2015-12-18 |
2017-07-31 |
Novartis Ag |
Anticuerpos dirigidos a cd32b y métodos de uso de los mismos
|
|
MA44140A
(fr)
|
2015-12-22 |
2021-05-19 |
Dana Farber Cancer Inst Inc |
Récepteur d'antigène chimérique (car) contre la mésothéline et anticorps contre l'inhibiteur de pd-l1 pour une utilisation combinée dans une thérapie anticancéreuse
|
|
CN109153975A
(zh)
|
2015-12-28 |
2019-01-04 |
诺华股份有限公司 |
制备嵌合抗原受体表达细胞的方法
|
|
CN116769054A
(zh)
|
2016-02-05 |
2023-09-19 |
奥里尼斯生物科学私人有限公司 |
双特异性信号传导剂及其用途
|
|
SG11201805941WA
(en)
|
2016-02-17 |
2018-09-27 |
Novartis Ag |
Tgfbeta 2 antibodies
|
|
CA3016287A1
(en)
|
2016-03-04 |
2017-09-08 |
Novartis Ag |
Cells expressing multiple chimeric antigen receptor (car) molecules and uses therefore
|
|
US11248057B2
(en)
|
2016-03-07 |
2022-02-15 |
Vib Vzw |
CD20 binding single domain antibodies
|
|
JP7034489B2
(ja)
|
2016-03-15 |
2022-03-14 |
アイタブメッド (エイチケイ) リミテッド |
多重特異性Fab融合タンパクおよびその使用
|
|
WO2017158396A1
(en)
|
2016-03-16 |
2017-09-21 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Cytidine deaminase inhibitors for the treatment of pancreatic cancer
|
|
EP3433615A1
(en)
|
2016-03-21 |
2019-01-30 |
Institut National de la Sante et de la Recherche Medicale (INSERM) |
Methods for diagnosis and treatment of solar lentigo
|
|
US11291721B2
(en)
|
2016-03-21 |
2022-04-05 |
Marengo Therapeutics, Inc. |
Multispecific and multifunctional molecules and uses thereof
|
|
RU2744959C2
(ru)
|
2016-03-23 |
2021-03-17 |
Мэбспейс Байосайнсиз (Сучжоу) Ко., Лтд |
Новые анти-pd-l1 антитела
|
|
JP7069032B2
(ja)
|
2016-03-24 |
2022-05-17 |
ミレニアム ファーマシューティカルズ, インコーポレイテッド |
がん免疫治療における胃腸の免疫関連有害事象の治療方法
|
|
TW201735949A
(zh)
|
2016-03-24 |
2017-10-16 |
千禧製藥公司 |
治療抗ctla4及抗pd-1組合治療中的胃腸道免疫相關不良事件之方法
|
|
EP3433274A1
(en)
|
2016-03-25 |
2019-01-30 |
Visterra, Inc. |
Formulation of antibody molecules to dengue virus
|
|
WO2017176762A1
(en)
|
2016-04-06 |
2017-10-12 |
Nanotics, Llc |
Particles comprising subparticles or nucleic acid scaffolds
|
|
US20190120838A1
(en)
|
2016-04-13 |
2019-04-25 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
Methods and kits for the rapid detection of the escherichia coli o25b-st131 clone
|
|
JP7125351B2
(ja)
|
2016-04-14 |
2022-08-24 |
2セブンティ バイオ インコーポレイテッド |
サルベージキメラ抗原受容体システム
|
|
SI3443096T1
(sl)
|
2016-04-15 |
2023-07-31 |
Novartis Ag |
Sestavki in postopki za selektivno izražanje himerni antigenskih receptorjev
|
|
WO2017181098A2
(en)
|
2016-04-15 |
2017-10-19 |
Visterra, Inc. |
Antibody molecules to zika virus and uses thereof
|
|
CA3019588A1
(en)
|
2016-04-20 |
2017-10-26 |
Merck Sharp & Dohme Corp. |
Cmv neutralizing antigen binding proteins
|
|
WO2017182605A1
(en)
|
2016-04-22 |
2017-10-26 |
Université Libre de Bruxelles |
A new biomarker expressed in pancreatic beta cells useful in imaging or targeting beta cells
|
|
US11243214B2
(en)
|
2016-04-22 |
2022-02-08 |
Université Libre de Bruxelles |
Biomarker expressed in pancreatic beta cells useful in imaging or targeting beta cells
|
|
JP7138567B2
(ja)
|
2016-04-27 |
2022-09-16 |
ノバルティス アーゲー |
成長分化因子15に対する抗体およびそれらの使用
|
|
PL3452507T3
(pl)
|
2016-05-02 |
2023-01-09 |
Prothena Biosciences Limited |
Immunoterapia tau
|
|
WO2017191108A1
(en)
|
2016-05-02 |
2017-11-09 |
Ablynx Nv |
Treatment of rsv infection
|
|
CN109563141A
(zh)
|
2016-05-13 |
2019-04-02 |
奥里尼斯生物科学公司 |
对非细胞结构的治疗性靶向
|
|
MA55697A
(fr)
|
2016-05-18 |
2022-02-23 |
Boehringer Ingelheim Int |
Molécules d'anticorps pour le traitement du cancer
|
|
CN109641046B
(zh)
|
2016-05-20 |
2023-11-07 |
哈普恩治疗公司 |
单链可变片段cd3结合蛋白质
|
|
US11623958B2
(en)
|
2016-05-20 |
2023-04-11 |
Harpoon Therapeutics, Inc. |
Single chain variable fragment CD3 binding proteins
|
|
BR112018073739A2
(pt)
|
2016-05-20 |
2019-02-26 |
Harpoon Therapeutics, Inc. |
proteína de ligação de albumina sérica de domínio único
|
|
WO2017202962A1
(en)
|
2016-05-24 |
2017-11-30 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical compositions for the treatment of non small cell lung cancer (nsclc) that coexists with chronic obstructive pulmonary disease (copd)
|
|
MA45123A
(fr)
|
2016-05-27 |
2019-04-10 |
Agenus Inc |
Anticorps anti-tim-3 et leurs méthodes d'utilisation
|
|
JP2019517473A
(ja)
|
2016-05-27 |
2019-06-24 |
アレクシオン ファーマシューティカルズ インコーポレイテッドAlexion Pharmaceuticals, Inc. |
難治性全身型重症筋無力症の処置のための方法
|
|
EP3463482B1
(en)
|
2016-06-07 |
2021-10-06 |
The Brigham and Women's Hospital, Inc. |
Methods relating to t peripheral helper cells in autoantibody-associated conditions
|
|
CN110381988A
(zh)
|
2016-06-15 |
2019-10-25 |
诺华股份有限公司 |
使用骨形态发生蛋白6(bmp6)的抑制剂治疗疾病的方法
|
|
US11197902B2
(en)
|
2016-06-24 |
2021-12-14 |
Ig Biosciences Corporation |
Prebiotic neutraceutical compositions and methods of treatment using the same
|
|
WO2018007442A1
(en)
|
2016-07-06 |
2018-01-11 |
Ablynx N.V. |
Treatment of il-6r related diseases
|
|
CA3030099A1
(en)
|
2016-07-08 |
2018-01-11 |
Staten Biotechnology B.V. |
Anti-apoc3 antibodies and methods of use thereof
|
|
BR112019000630A2
(pt)
|
2016-07-13 |
2019-07-09 |
Biogen Ma Inc |
regimes de dosagem dos antagonistas de lingo-1 e usos para tratamento de distúrbios desmielinizante
|
|
CN120285179A
(zh)
|
2016-07-15 |
2025-07-11 |
诺华股份有限公司 |
使用与激酶抑制剂组合的嵌合抗原受体治疗和预防细胞因子释放综合征
|
|
WO2018014260A1
(en)
|
2016-07-20 |
2018-01-25 |
Nanjing Legend Biotech Co., Ltd. |
Multispecific antigen binding proteins and methods of use thereof
|
|
WO2018017964A2
(en)
|
2016-07-21 |
2018-01-25 |
Emory University |
Ebola virus antibodies and binding agents derived therefrom
|
|
IL264486B2
(en)
|
2016-07-28 |
2025-04-01 |
Novartis Ag |
Combination therapies of chimeric antigen receptors and PD-1 inhibitors
|
|
NL2017267B1
(en)
|
2016-07-29 |
2018-02-01 |
Aduro Biotech Holdings Europe B V |
Anti-pd-1 antibodies
|
|
SG11201900885VA
(en)
|
2016-08-01 |
2019-02-27 |
Novartis Ag |
Treatment of cancer using a chimeric antigen receptor in combination with an inhibitor of a pro-m2 macrophage molecule
|
|
NL2017270B1
(en)
|
2016-08-02 |
2018-02-09 |
Aduro Biotech Holdings Europe B V |
New anti-hCTLA-4 antibodies
|
|
KR102777127B1
(ko)
|
2016-08-02 |
2025-03-07 |
비스테라, 인크. |
조작된 폴리펩티드 및 그의 용도
|
|
CA3032826A1
(en)
|
2016-08-03 |
2018-02-08 |
Nextcure, Inc. |
Compositions and methods for modulating lair signal transduction
|
|
WO2018029182A1
(en)
|
2016-08-08 |
2018-02-15 |
Ablynx N.V. |
Il-6r single variable domain antibodies for treatment of il-6r related diseases
|
|
EP3512880A1
(en)
|
2016-09-15 |
2019-07-24 |
Ablynx NV |
Immunoglobulin single variable domains directed against macrophage migration inhibitory factor
|
|
US11111313B2
(en)
|
2016-09-20 |
2021-09-07 |
WuXi Biologics Ireland Limited |
Anti-PCSK9 antibodies
|
|
RU2759334C2
(ru)
|
2016-09-21 |
2021-11-12 |
Нексткьюр, Инк. |
Антитела против siglec-15 и способы их применения
|
|
EP4360714A3
(en)
|
2016-09-21 |
2024-07-24 |
Nextcure, Inc. |
Antibodies for siglec-15 and methods of use thereof
|
|
US11673971B2
(en)
|
2016-09-23 |
2023-06-13 |
Marengo Therapeutics, Inc. |
Multispecific antibody molecules comprising lambda and kappa light chains
|
|
US20190248920A1
(en)
|
2016-09-23 |
2019-08-15 |
Csl Limited |
Coagulation factor binding proteins and uses thereof
|
|
EP3519438A1
(en)
|
2016-09-30 |
2019-08-07 |
VHsquared Limited |
Compositions
|
|
EP3523331A1
(en)
|
2016-10-07 |
2019-08-14 |
Novartis AG |
Chimeric antigen receptors for the treatment of cancer
|
|
WO2018068201A1
(en)
|
2016-10-11 |
2018-04-19 |
Nanjing Legend Biotech Co., Ltd. |
Single-domain antibodies and variants thereof against ctla-4
|
|
CA3037380A1
(en)
|
2016-10-11 |
2018-04-19 |
Agenus Inc. |
Anti-lag-3 antibodies and methods of use thereof
|
|
US20190276524A1
(en)
|
2016-10-12 |
2019-09-12 |
Alexion Pharmaceuticals, Inc. |
Efficacy of an anti-c5 antibody in the prevention of antibody mediated rejection in sensitized recipients of a kidney transplant
|
|
CN110520530A
(zh)
|
2016-10-18 |
2019-11-29 |
明尼苏达大学董事会 |
肿瘤浸润性淋巴细胞和治疗方法
|
|
ES2888904T3
(es)
|
2016-10-19 |
2022-01-10 |
Alexion Pharma Inc |
Un método de cuantificación de C5a sin unir en una muestra
|
|
US11965884B2
(en)
|
2016-10-19 |
2024-04-23 |
Alexion Pharmaceuticals, Inc. |
Method of quantitating unbound C5 in a sample
|
|
ES2978486T3
(es)
|
2016-10-21 |
2024-09-13 |
Ose Immunotherapeutics |
Métodos para promover la respuesta de linfocitos T
|
|
US20200057046A1
(en)
|
2016-10-27 |
2020-02-20 |
Alexion Pharmaceuticals, Inc. |
Assay for c5b-9 deposition in complement-associated disorders
|
|
US20190263926A1
(en)
|
2016-10-28 |
2019-08-29 |
Astute Medical, Inc. |
Use of Antibodies to TIMP-2 for the Improvement of Renal Function
|
|
WO2018078083A1
(en)
|
2016-10-28 |
2018-05-03 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
New method for treating multiple myeloma
|
|
US11779604B2
(en)
|
2016-11-03 |
2023-10-10 |
Kymab Limited |
Antibodies, combinations comprising antibodies, biomarkers, uses and methods
|
|
KR20240005168A
(ko)
|
2016-11-04 |
2024-01-11 |
2세븐티 바이오, 인코포레이티드 |
항-bcma car t 세포 조성물
|
|
KR102539159B1
(ko)
|
2016-11-07 |
2023-06-02 |
주식회사 뉴라클사이언스 |
서열 유사성을 가진 항-패밀리 19, 멤버 a5 항체 및 그것의 사용 방법
|
|
AU2017361846B2
(en)
|
2016-11-16 |
2024-08-22 |
Ablynx Nv |
T cell recruiting polypeptides capable of binding CD123 and TCR alpha/beta
|
|
EP3541833B1
(en)
|
2016-11-17 |
2024-01-24 |
2seventy bio, Inc. |
Tgf beta signal convertor
|
|
US11773163B2
(en)
|
2016-11-21 |
2023-10-03 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical compositions for the prophylactic treatment of metastases
|
|
JP6812551B2
(ja)
|
2016-11-23 |
2021-01-13 |
ハープーン セラピューティクス,インク. |
前立腺特異的膜抗原結合タンパク質
|
|
JP7215997B2
(ja)
|
2016-11-23 |
2023-01-31 |
ハープーン セラピューティクス,インク. |
前立腺特異的膜抗原(psma)を標的とする三重特異性タンパク質と使用方法
|
|
WO2018099968A1
(en)
|
2016-11-29 |
2018-06-07 |
Ablynx N.V. |
Treatment of infection by respiratory syncytial virus (rsv)
|
|
US10759855B2
(en)
|
2016-12-02 |
2020-09-01 |
Rigel Pharmaceuticals, Inc. |
Antigen binding molecules to TIGIT
|
|
EP3551047A1
(en)
|
2016-12-07 |
2019-10-16 |
Progenity, Inc. |
Gastrointestinal tract detection methods, devices and systems
|
|
FI3551660T3
(fi)
|
2016-12-07 |
2023-12-11 |
Agenus Inc |
Anti-ctla-4-vasta-aineita ja niiden käyttömenetelmiä
|
|
EP3551225A1
(en)
|
2016-12-07 |
2019-10-16 |
Agenus Inc. |
Antibodies and methods of use thereof
|
|
WO2018112237A1
(en)
|
2016-12-14 |
2018-06-21 |
Progenity Inc. |
Treatment of a disease of the gastrointestinal tract with an il-6r inhibitor
|
|
JP7150723B2
(ja)
|
2016-12-14 |
2022-10-11 |
ビオラ・セラピューティクス・インコーポレイテッド |
消化管疾病のインテグリン阻害薬による治療
|
|
EP4190318A1
(en)
|
2016-12-14 |
2023-06-07 |
Biora Therapeutics, Inc. |
Treatment of a disease of the gastrointestinal tract with a jak inhibitor and devices
|
|
WO2018112232A1
(en)
|
2016-12-14 |
2018-06-21 |
Progenity Inc. |
Treatment of a disease of the gastrointestinal tract with an il-12/il-23 inhibitor released using an ingestible device
|
|
TW201834711A
(zh)
|
2016-12-14 |
2018-10-01 |
美商寶珍那提公司 |
以tnf抑制劑治療胃腸道疾病
|
|
CA3045310A1
(en)
|
2016-12-14 |
2018-06-21 |
Progenity, Inc. |
Treatment of a disease of the gastrointestinal tract with a chemokine/chemokine receptor inhibitor
|
|
CA3046023A1
(en)
|
2016-12-14 |
2018-06-21 |
Progenity, Inc. |
Treatment of a disease of the gastrointestinal tract with an immunosuppressant
|
|
CA3046019A1
(en)
|
2016-12-14 |
2018-06-21 |
Progenity Inc. |
Treatment of a disease of the gastrointestinal tract with a tlr modulator
|
|
WO2018112235A1
(en)
|
2016-12-14 |
2018-06-21 |
Progenity Inc. |
Treatment of a disease of the gastrointestinal tract with a smad7 inhibitor
|
|
WO2018112256A1
(en)
|
2016-12-14 |
2018-06-21 |
Progenity Inc. |
Treatment of a disease of the gastrointestinal tract with an il-1 inhibitor
|
|
EP3360898A1
(en)
|
2017-02-14 |
2018-08-15 |
Boehringer Ingelheim International GmbH |
Bispecific anti-tnf-related apoptosis-inducing ligand receptor 2 and anti-cadherin 17 binding molecules for the treatment of cancer
|
|
MY201744A
(en)
|
2016-12-23 |
2024-03-15 |
Visterra Inc |
Binding polypeptides and methods of making the same
|
|
AU2017383232B2
(en)
|
2016-12-23 |
2024-09-12 |
Novartis Ag |
Factor XI antibodies and methods of use
|
|
ES2988845T3
(es)
|
2017-01-09 |
2024-11-21 |
Onkosxcel Therapeutics Llc |
Procedimientos predictivos y diagnósticos para cáncer de próstata
|
|
EP3571223B1
(en)
|
2017-01-18 |
2024-09-18 |
Visterra, Inc. |
Antibody molecule-drug conjugates and uses thereof
|
|
SG10202109874VA
(en)
|
2017-01-19 |
2021-10-28 |
Open Monoclonal Tech Inc |
Human antibodies from transgenic rodents with multiple heavy chain immunoglobulin loci
|
|
EP4043485A1
(en)
|
2017-01-26 |
2022-08-17 |
Novartis AG |
Cd28 compositions and methods for chimeric antigen receptor therapy
|
|
WO2018141753A1
(en)
|
2017-01-31 |
2018-08-09 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Method for treating squamous cell carcinomas
|
|
EP3577133A1
(en)
|
2017-02-06 |
2019-12-11 |
Orionis Biosciences NV |
Targeted chimeric proteins and uses thereof
|
|
JP6991246B2
(ja)
|
2017-02-08 |
2022-02-03 |
ノバルティス アーゲー |
Fgf21模倣抗体及びその使用
|
|
US20200291089A1
(en)
|
2017-02-16 |
2020-09-17 |
Elstar Therapeutics, Inc. |
Multifunctional molecules comprising a trimeric ligand and uses thereof
|
|
US11964002B2
(en)
|
2017-02-28 |
2024-04-23 |
Vib Vzw |
Means and methods for oral protein delivery
|
|
US11535668B2
(en)
|
2017-02-28 |
2022-12-27 |
Harpoon Therapeutics, Inc. |
Inducible monovalent antigen binding protein
|
|
US20200048359A1
(en)
|
2017-02-28 |
2020-02-13 |
Novartis Ag |
Shp inhibitor compositions and uses for chimeric antigen receptor therapy
|
|
DE202018006693U1
(de)
|
2017-03-14 |
2022-03-08 |
Nanotag Biotechnologies Gmbh |
Target-Detektion mit einem monovalenten Antikörper
|
|
CN110753702B
(zh)
|
2017-03-15 |
2022-09-20 |
清华大学 |
抗trkb抗体
|
|
WO2018167283A1
(en)
|
2017-03-17 |
2018-09-20 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for the diagnosis and treatment of pancreatic ductal adenocarcinoma associated neural remodeling
|
|
CA3054837A1
(en)
|
2017-03-24 |
2018-09-27 |
Novartis Ag |
Methods for preventing and treating heart disease
|
|
KR20190133198A
(ko)
|
2017-03-27 |
2019-12-02 |
셀진 코포레이션 |
면역원성의 감소를 위한 방법 및 조성물
|
|
AU2018244922A1
(en)
|
2017-03-30 |
2019-09-12 |
Biora Therapeutics, Inc. |
Treatment of a disease of the gastrointestinal tract with live biotherapeutics
|
|
WO2018183934A1
(en)
|
2017-03-30 |
2018-10-04 |
Progenity Inc. |
Treatment of a disease of the gastrointestinal tract with a chst15 inhibitor
|
|
WO2018183932A1
(en)
|
2017-03-30 |
2018-10-04 |
Progenity Inc. |
Treatment of a disease of the gastrointestinal tract with a il-13 inhibitor
|
|
US11596670B2
(en)
|
2017-03-30 |
2023-03-07 |
Biora Therapeutics, Inc. |
Treatment of a disease of the gastrointestinal tract with IL-10 or an IL-10 agonist
|
|
US20210138213A1
(en)
|
2017-03-30 |
2021-05-13 |
Progenity, Inc. |
Treatment of a disease of the gastrointestinal tract with an immune modulatory agent released using an ingestible device
|
|
WO2018187227A1
(en)
|
2017-04-03 |
2018-10-11 |
Concologie, Inc. |
Methods for treating cancer using ps-targeting antibodies with immuno-oncology agents
|
|
WO2018185516A1
(en)
|
2017-04-05 |
2018-10-11 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical compositions for treating cardiovascular toxicity induced by anti-cancer therapy
|
|
EP3610264A1
(en)
|
2017-04-13 |
2020-02-19 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for the diagnosis and treatment of pancreatic ductal adenocarcinoma
|
|
BR112019017241A2
(pt)
|
2017-04-13 |
2020-04-14 |
Agenus Inc |
anticorpos anti-cd137 e métodos de uso dos mesmos
|
|
WO2018189403A1
(en)
|
2017-04-14 |
2018-10-18 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical compositions for the treatment of cancer
|
|
US20200033347A1
(en)
|
2017-04-18 |
2020-01-30 |
Universite Libre De Bruxelles |
Biomarkers And Targets For Proliferative Diseases
|
|
WO2018195034A1
(en)
|
2017-04-19 |
2018-10-25 |
Alexion Pharmaceuticals, Inc. |
Efficacy of an anti-c5 antibody in the prevention of antibody mediated rejection in sensitized recipients of a kidney transplant
|
|
AU2018256406A1
(en)
|
2017-04-19 |
2019-10-17 |
Marengo Therapeutics, Inc. |
Multispecific molecules and uses thereof
|
|
JP2020517242A
(ja)
|
2017-04-21 |
2020-06-18 |
スターテン・バイオテクノロジー・ベー・フェー |
抗ApoC3抗体およびその使用方法
|
|
EP3615055A1
(en)
|
2017-04-28 |
2020-03-04 |
Novartis AG |
Cells expressing a bcma-targeting chimeric antigen receptor, and combination therapy with a gamma secretase inhibitor
|
|
EP3615566B1
(en)
|
2017-04-28 |
2023-12-20 |
Marengo Therapeutics, Inc. |
Multispecific molecules comprising a non-immunoglobulin heterodimerization domain and uses thereof
|
|
WO2018201051A1
(en)
|
2017-04-28 |
2018-11-01 |
Novartis Ag |
Bcma-targeting agent, and combination therapy with a gamma secretase inhibitor
|
|
TW202402800A
(zh)
|
2017-05-01 |
2024-01-16 |
美商艾吉納斯公司 |
抗tigit抗體類和使用彼等之方法
|
|
WO2018206734A1
(en)
|
2017-05-11 |
2018-11-15 |
Vib Vzw |
Glycosylation of variable immunoglobulin domains
|
|
CA3063362A1
(en)
|
2017-05-12 |
2018-11-15 |
Harpoon Therapeutics, Inc. |
Msln targeting trispecific proteins and methods of use
|
|
CA3063359A1
(en)
|
2017-05-12 |
2018-11-15 |
Harpoon Therapeutics, Inc. |
Mesothelin binding proteins
|
|
KR20200006985A
(ko)
|
2017-05-12 |
2020-01-21 |
오거스타 유니버시티 리서치 인스티튜트, 인크. |
인간 알파 태아단백-특이적 t 세포 수용체 및 이의 용도
|
|
JOP20190256A1
(ar)
|
2017-05-12 |
2019-10-28 |
Icahn School Med Mount Sinai |
فيروسات داء نيوكاسل واستخداماتها
|
|
US11225514B2
(en)
|
2017-05-30 |
2022-01-18 |
The Regents Of The University Of California |
Nanobodies against cystic fibrosis transmembrane conductance regulator (CFTR) inhibitory factor (Cif)
|
|
US11033636B2
(en)
|
2017-05-31 |
2021-06-15 |
Boehringer Ingelheim International Gmbh |
Polypeptides antagonizing Wnt signaling in tumor cells
|
|
EP3630836A1
(en)
|
2017-05-31 |
2020-04-08 |
Elstar Therapeutics, Inc. |
Multispecific molecules that bind to myeloproliferative leukemia (mpl) protein and uses thereof
|
|
IL270951B2
(en)
|
2017-06-02 |
2025-05-01 |
Merck Patent Gmbh |
ADAMTS5, MMP13 and aggrecan-binding polypeptides
|
|
LT3630847T
(lt)
|
2017-06-02 |
2024-12-10 |
Merck Patent Gmbh |
Adamts surišantys imunoglobulinai
|
|
CN110997716B
(zh)
|
2017-06-02 |
2024-03-15 |
埃博灵克斯股份有限公司 |
结合聚集蛋白聚糖的免疫球蛋白
|
|
EP3630822A1
(en)
|
2017-06-02 |
2020-04-08 |
Boehringer Ingelheim International GmbH |
Anti-cancer combination therapy
|
|
KR102778120B1
(ko)
|
2017-06-02 |
2025-03-06 |
메르크 파텐트 게엠베하 |
Mmp13 결합성 면역글로불린
|
|
EP3415010A1
(en)
|
2017-06-13 |
2018-12-19 |
Agrosavfe Nv |
Insect-controlling polypeptides and methods
|
|
GB201709379D0
(en)
|
2017-06-13 |
2017-07-26 |
Univ Leuven Kath |
Humanised ADAMTS13 binding antibodies
|
|
WO2018229715A1
(en)
|
2017-06-16 |
2018-12-20 |
Novartis Ag |
Compositions comprising anti-cd32b antibodies and methods of use thereof
|
|
WO2018236904A1
(en)
|
2017-06-19 |
2018-12-27 |
Surface Oncology, Inc. |
Combination of anti-cd47 antibodies and cell death-inducing agents, and uses thereof
|
|
WO2018237173A1
(en)
|
2017-06-22 |
2018-12-27 |
Novartis Ag |
Antibody molecules to cd73 and uses thereof
|
|
EP3641812A1
(en)
|
2017-06-22 |
2020-04-29 |
Novartis AG |
Antibody molecules to cd73 and uses thereof
|
|
EP3645563A4
(en)
|
2017-06-27 |
2021-03-17 |
Neuracle Science Co., Ltd |
ANTI-FAM19A5 ANTIBODIES AND USES THEREOF
|
|
AU2018292618A1
(en)
|
2017-06-27 |
2019-12-19 |
Novartis Ag |
Dosage regimens for anti-TIM-3 antibodies and uses thereof
|
|
WO2019000223A1
(en)
|
2017-06-27 |
2019-01-03 |
Nanjing Legend Biotech Co., Ltd. |
ENABLERS OF IMMUNE EFFECTOR CELLS OF CHIMERIC ANTIBODIES AND METHODS OF USE THEREOF
|
|
JP2020525421A
(ja)
|
2017-06-28 |
2020-08-27 |
ノバルティス アーゲー |
尿失禁を予防及び治療するための方法
|
|
EP3645041A4
(en)
|
2017-06-28 |
2021-03-17 |
The Rockefeller University |
AGONISTIC ANTIBODY-ANTIBODY-ACTIVE INGREDIENT CONJUGATES AGAINST MERTK AND THEIR USES
|
|
WO2019006418A2
(en)
|
2017-06-30 |
2019-01-03 |
Intima Bioscience, Inc. |
ADENO-ASSOCIATED VIRAL VECTORS FOR GENE THERAPY
|
|
BR112019028269A2
(pt)
|
2017-07-11 |
2020-07-14 |
Alexion Pharmaceuticals, Inc. |
polipeptídeos que se ligam ao componente c5 do complemento ou à albumina sérica e suas proteínas de fusão
|
|
EP3652209A2
(en)
|
2017-07-11 |
2020-05-20 |
Compass Therapeutics LLC |
Agonist antibodies that bind human cd137 and uses thereof
|
|
WO2019012030A1
(en)
|
2017-07-13 |
2019-01-17 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
DHODH INHIBITOR AND CHK1 INHIBITOR FOR THE TREATMENT OF CANCER
|
|
CA3070253A1
(en)
|
2017-07-19 |
2019-01-24 |
Vib Vzw |
Serum albumin binding agents
|
|
EP3431496A1
(en)
|
2017-07-19 |
2019-01-23 |
Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. |
Anti- isoasp7 amyloid beta antibodies and uses thereof
|
|
KR20250025039A
(ko)
|
2017-07-20 |
2025-02-20 |
노파르티스 아게 |
항-lag-3 항체의 투여 요법 및 그의 용도
|
|
WO2019016784A1
(en)
|
2017-07-21 |
2019-01-24 |
Universidade De Coimbra |
ANTI-NUCLEOLIN ANTIBODIES
|
|
WO2019020480A1
(en)
|
2017-07-24 |
2019-01-31 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
ANTIBODIES AND PEPTIDES FOR TREATING HCMV RELATED DISEASES
|
|
ES2965486T3
(es)
|
2017-07-27 |
2024-04-15 |
Alexion Pharma Inc |
Formulaciones de anticuerpos anti-C5 de alta concentración
|
|
JP2020529605A
(ja)
|
2017-08-01 |
2020-10-08 |
コンパス セラピューティクス リミテッド ライアビリティ カンパニー |
濾過およびクロマトグラフィ用ポッドならびにその使用方法
|
|
US20200306516A1
(en)
|
2017-08-14 |
2020-10-01 |
Progenity, Inc. |
Treatment of a disease of the gastrointestinal tract with glatiramer or a pharmaceutically acceptable salt thereof
|
|
WO2019035938A1
(en)
|
2017-08-16 |
2019-02-21 |
Elstar Therapeutics, Inc. |
MULTISPECIFIC MOLECULES BINDING TO BCMA AND USES THEREOF
|
|
EP3684811A2
(en)
|
2017-08-17 |
2020-07-29 |
Massachusetts Institute of Technology |
Multiple specificity binders of cxc chemokines and uses thereof
|
|
JP2020532991A
(ja)
|
2017-09-07 |
2020-11-19 |
オーガスタ ユニバーシティ リサーチ インスティテュート,インコーポレーテッド |
プログラム細胞死タンパク質1に対する抗体
|
|
JP7733443B2
(ja)
|
2017-09-11 |
2025-09-03 |
モナシュ ユニバーシティー |
ヒトトロンビン受容体par4に対する結合タンパク質
|
|
JP7330174B2
(ja)
|
2017-09-20 |
2023-08-21 |
アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル |
オートファジーをモジュレーションするための方法及び医薬組成物
|
|
MY205689A
(en)
|
2017-10-02 |
2024-11-06 |
Visterra Inc |
Antibody molecules to cd138 and uses thereof
|
|
ES2759622T3
(es)
|
2017-10-02 |
2020-05-11 |
Certest Biotec S L |
Anticuerpos anti-Dps y dispositivos de prueba para la detección de bacterias del género Campylobacter
|
|
EP3694552A1
(en)
|
2017-10-10 |
2020-08-19 |
Tilos Therapeutics, Inc. |
Anti-lap antibodies and uses thereof
|
|
IL315737A
(en)
|
2017-10-13 |
2024-11-01 |
Harpoon Therapeutics Inc |
B-cell maturation antigen-binding proteins
|
|
UA129446C2
(uk)
|
2017-10-13 |
2025-04-30 |
Гарпун Терап'Ютікс, Інк. |
Триспецифічні білки і способи їх застосування
|
|
WO2019073080A1
(en)
|
2017-10-13 |
2019-04-18 |
Ose Immunotherapeutics |
ANTI-SIRPA MODIFIED ANTIBODIES AND USES THEREOF
|
|
CN111247165B
(zh)
|
2017-10-18 |
2023-11-10 |
Csl有限公司 |
人血清白蛋白变体及其应用
|
|
WO2019077132A1
(en)
|
2017-10-19 |
2019-04-25 |
Debiopharm International S.A. |
COMBINATION PRODUCT FOR THE TREATMENT OF CANCER
|
|
US20210040205A1
(en)
|
2017-10-25 |
2021-02-11 |
Novartis Ag |
Antibodies targeting cd32b and methods of use thereof
|
|
MX2020004229A
(es)
|
2017-10-25 |
2020-07-22 |
Novartis Ag |
Metodos de produccion de celulas que expresan receptores antigenicos quimericos.
|
|
KR20200070355A
(ko)
|
2017-10-26 |
2020-06-17 |
알렉시온 파마슈티칼스, 인코포레이티드 |
발작성 야간 혈색소뇨 (pnh) 및 비정형 용혈성 요독 증후군 (ahus)의 치료를 위한 항-c5 항체의 투여량 및 투여
|
|
WO2019089753A2
(en)
|
2017-10-31 |
2019-05-09 |
Compass Therapeutics Llc |
Cd137 antibodies and pd-1 antagonists and uses thereof
|
|
WO2019086548A1
(en)
|
2017-10-31 |
2019-05-09 |
Vib Vzw |
Novel antigen-binding chimeric proteins and methods and uses thereof
|
|
BR112020008514A2
(pt)
|
2017-10-31 |
2020-10-20 |
Staten Biotechnology B.V. |
anticorpos anti-apoc3 e métodos de uso dos mesmos
|
|
US20210179709A1
(en)
|
2017-10-31 |
2021-06-17 |
Novartis Ag |
Anti-car compositions and methods
|
|
US20190160102A1
(en)
|
2017-11-03 |
2019-05-30 |
Rubius Therapeutics, Inc. |
Compositions and methods related to therapeutic cell systems for tumor growth inhibition
|
|
AU2018368731A1
(en)
|
2017-11-16 |
2020-05-14 |
Novartis Ag |
Combination therapies
|
|
US11851497B2
(en)
|
2017-11-20 |
2023-12-26 |
Compass Therapeutics Llc |
CD137 antibodies and tumor antigen-targeting antibodies and uses thereof
|
|
PL3717011T3
(pl)
|
2017-11-29 |
2023-03-27 |
Csl Limited |
Sposób leczenia lub zapobiegania uszkodzeniu niedokrwienno- reperfuzyjnemu
|
|
WO2019106126A1
(en)
|
2017-12-01 |
2019-06-06 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Mdm2 modulators for the diagnosis and treatment of liposarcoma
|
|
CN112218943B
(zh)
|
2017-12-05 |
2025-10-21 |
塞利亚德股份公司 |
减少表达基于nkg2d的受体的免疫细胞的杀伤剂
|
|
CN112236514A
(zh)
|
2017-12-05 |
2021-01-15 |
塞利亚德股份公司 |
改善细胞过继转移的持久性的组合物和方法
|
|
JP7348899B2
(ja)
|
2017-12-08 |
2023-09-21 |
マレンゴ・セラピューティクス,インコーポレーテッド |
多重特異性分子及びその使用
|
|
WO2019121872A1
(en)
|
2017-12-20 |
2019-06-27 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for the diagnosis and treatment of liver cancer
|
|
WO2019129054A1
(zh)
|
2017-12-27 |
2019-07-04 |
信达生物制药(苏州)有限公司 |
三链抗体、其制备方法及其用途
|
|
CN109970857B
(zh)
|
2017-12-27 |
2022-09-30 |
信达生物制药(苏州)有限公司 |
抗pd-l1抗体及其用途
|
|
WO2019129136A1
(zh)
|
2017-12-27 |
2019-07-04 |
信达生物制药(苏州)有限公司 |
抗pd-l1抗体及其用途
|
|
CN109970856B
(zh)
|
2017-12-27 |
2022-08-23 |
信达生物制药(苏州)有限公司 |
抗lag-3抗体及其用途
|
|
WO2019129137A1
(zh)
|
2017-12-27 |
2019-07-04 |
信达生物制药(苏州)有限公司 |
抗lag-3抗体及其用途
|
|
CN117050184A
(zh)
|
2017-12-28 |
2023-11-14 |
南京传奇生物科技有限公司 |
针对tigit的单域抗体和其变体
|
|
CN108218990B
(zh)
|
2017-12-29 |
2021-03-02 |
南京优迈生物科技有限公司 |
分离的抗体或其抗原结合片段及其在肿瘤治疗中的应用
|
|
EP3737692A4
(en)
|
2018-01-09 |
2021-09-29 |
Elstar Therapeutics, Inc. |
CALRETICULIN AND MODIFIED T-LYMPHOCYTES BINDING CONSTRUCTIONS FOR THE TREATMENT OF DISEASES
|
|
US20190330591A1
(en)
|
2018-01-10 |
2019-10-31 |
Rubius Therapeutics, Inc. |
Amplifiable rnas for therapeutic cell systems
|
|
JP7366908B2
(ja)
|
2018-01-15 |
2023-10-23 |
ナンジン レジェンド バイオテック カンパニー,リミテッド |
Pd-1に対する単一ドメイン抗体及びその変異体
|
|
EP3740231A4
(en)
|
2018-01-18 |
2022-03-23 |
California Institute of Technology |
PROGRAMMABLE PROTEIN CIRCUITS IN LIVING CELLS
|
|
US11965191B2
(en)
|
2018-01-18 |
2024-04-23 |
California Institute Of Technology |
Programmable protein circuits in living cells
|
|
KR20200112913A
(ko)
|
2018-01-23 |
2020-10-05 |
넥스트큐어 인코포레이티드 |
B7-h4 항체 및 그 사용 방법
|
|
JP2021510594A
(ja)
|
2018-01-25 |
2021-04-30 |
アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル |
臓器の虚血再灌流傷害を予防する方法における使用のためのil−33のアンタゴニスト
|
|
WO2019148089A1
(en)
|
2018-01-26 |
2019-08-01 |
Orionis Biosciences Inc. |
Xcr1 binding agents and uses thereof
|
|
CA3090249A1
(en)
|
2018-01-31 |
2019-08-08 |
Novartis Ag |
Combination therapy using a chimeric antigen receptor
|
|
US12180285B2
(en)
|
2018-02-01 |
2024-12-31 |
Memorial Sloan Kettering Cancer Center |
Antibodies to galectin-3 and methods of use thereof
|
|
WO2019151865A1
(en)
|
2018-02-05 |
2019-08-08 |
Stichting Vu |
Inverse agonistic anti-us28 antibodies
|
|
MX2020008208A
(es)
|
2018-02-05 |
2020-11-09 |
Orionis Biosciences Inc |
Agentes de unión a fibroblastos y uso de estos.
|
|
MY204220A
(en)
|
2018-02-06 |
2024-08-16 |
Ablynx Nv |
Methods of treating initial episode of ttp with immunoglobulin single variable domains
|
|
WO2019157191A1
(en)
|
2018-02-07 |
2019-08-15 |
Georgia Tech Research Corporation |
Methods for multiplexed cell isolation using dna gates
|
|
WO2019156566A1
(en)
|
2018-02-12 |
2019-08-15 |
Umc Utrecht Holding B.V. |
Bispecific molecules comprising gamma-delta tcr and t-cell or nk cell binding domain
|
|
WO2019155041A1
(en)
|
2018-02-12 |
2019-08-15 |
Vib Vzw |
Gβγ COMPLEX ANTIBODIES AND USES THEREOF
|
|
EP3752194A4
(en)
|
2018-02-13 |
2022-03-16 |
Checkmate Pharmaceuticals, Inc. |
COMPOSITIONS AND METHODS FOR TUMOR IMMUNOTHERAPY
|
|
WO2019158512A1
(en)
|
2018-02-13 |
2019-08-22 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for the prognosis and the treatment of glioblastoma
|
|
EP3758742A1
(en)
|
2018-03-01 |
2021-01-06 |
Vrije Universiteit Brussel |
Human pd-l1-binding immunoglobulins
|
|
WO2019169229A1
(en)
|
2018-03-01 |
2019-09-06 |
Nextcure, Inc. |
Klrg1 binding compositions and methods of use thereof
|
|
NL2020520B1
(en)
|
2018-03-02 |
2019-09-12 |
Labo Bio Medical Invest B V |
Multispecific binding molecules for the prevention, treatment and diagnosis of neurodegenerative disorders
|
|
AU2019233603B2
(en)
|
2018-03-13 |
2025-06-26 |
Smivet B.V. |
Single domain antibodies binding to tetanus neurotoxin
|
|
US20210009711A1
(en)
|
2018-03-14 |
2021-01-14 |
Elstar Therapeutics, Inc. |
Multifunctional molecules and uses thereof
|
|
MX394121B
(es)
|
2018-03-14 |
2025-03-24 |
Surface Oncology Inc |
Anticuerpos que se unen a cd39 y sus usos
|
|
US12152073B2
(en)
|
2018-03-14 |
2024-11-26 |
Marengo Therapeutics, Inc. |
Multifunctional molecules that bind to calreticulin and uses thereof
|
|
US11661452B2
(en)
|
2018-03-20 |
2023-05-30 |
WuXi Biologics Ireland Limited |
Anti-lag-3 antibody polypeptide
|
|
EP3768725A4
(en)
|
2018-03-20 |
2021-06-02 |
Wuxi Biologics Ireland Limited |
NEW ANTI-TIM-3 ANTIBODIES
|
|
BR112020018918A2
(pt)
|
2018-03-22 |
2021-01-05 |
Surface Oncology, Inc. |
Anticorpos anti-il-27 e usos dos mesmos
|
|
KR102879500B1
(ko)
|
2018-03-23 |
2025-10-31 |
유니베르시테 리브레 드 브룩크젤즈 |
Wnt 시그널링 작용제 분자
|
|
WO2019178645A1
(en)
|
2018-03-23 |
2019-09-26 |
Csl Limited |
Method of treating asthma
|
|
CN112384236A
(zh)
|
2018-03-27 |
2021-02-19 |
Umc乌得勒支控股有限公司 |
用于治疗微血管血栓形成的靶向溶栓
|
|
WO2019184909A1
(zh)
|
2018-03-27 |
2019-10-03 |
信达生物制药(苏州)有限公司 |
新型抗体分子、其制备方法及其用途
|
|
US20210047696A1
(en)
|
2018-03-28 |
2021-02-18 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical compositions for treating cancer
|
|
AU2019241350B2
(en)
|
2018-03-30 |
2025-10-02 |
Nanjing Legend Biotech Co., Ltd. |
Single-domain antibodies against LAG-3 and uses thereof
|
|
WO2019193375A1
(en)
|
2018-04-04 |
2019-10-10 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of fzd7 inhibitors for the treatment of retinal neovascularization
|
|
EP3775218A1
(en)
|
2018-04-09 |
2021-02-17 |
Checkmate Pharmaceuticals |
Packaging oligonucleotides into virus-like particles
|
|
WO2019200357A1
(en)
|
2018-04-12 |
2019-10-17 |
Surface Oncology, Inc. |
Biomarker for cd47 targeting therapeutics and uses therefor
|
|
US20210147547A1
(en)
|
2018-04-13 |
2021-05-20 |
Novartis Ag |
Dosage Regimens For Anti-Pd-L1 Antibodies And Uses Thereof
|
|
WO2019197683A1
(en)
|
2018-04-13 |
2019-10-17 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for predicting outcome and treatment of patients suffering from prostate cancer or breast cancer
|
|
WO2019207030A1
(en)
|
2018-04-26 |
2019-10-31 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for predicting a response with an immune checkpoint inhibitor in a patient suffering from a lung cancer
|
|
US20210047405A1
(en)
|
2018-04-27 |
2021-02-18 |
Novartis Ag |
Car t cell therapies with enhanced efficacy
|
|
US12048745B2
(en)
|
2018-05-01 |
2024-07-30 |
Augusta University Research Institute, Inc. |
Methods for detecting and reversing immune therapy resistance
|
|
WO2019211370A1
(en)
|
2018-05-03 |
2019-11-07 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical compositions for treating cancer
|
|
WO2019211369A1
(en)
|
2018-05-03 |
2019-11-07 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical compositions for treating cancer
|
|
AU2019265888A1
(en)
|
2018-05-10 |
2020-11-26 |
Neuracle Science Co., Ltd. |
Anti-family with sequence similarity 19, member A5 antibodies and method of use thereof
|
|
US20190345261A1
(en)
|
2018-05-10 |
2019-11-14 |
Sensei Biotherapeutics, Inc. |
Aspartate beta-hydroxylase chimeric antigen receptors and uses thereof
|
|
WO2019222283A1
(en)
|
2018-05-14 |
2019-11-21 |
Harpoon Therapeutics, Inc. |
Binding moiety for conditional activation of immunoglobulin molecules
|
|
EP3569618A1
(en)
|
2018-05-19 |
2019-11-20 |
Boehringer Ingelheim International GmbH |
Antagonizing cd73 antibody
|
|
WO2019226658A1
(en)
|
2018-05-21 |
2019-11-28 |
Compass Therapeutics Llc |
Multispecific antigen-binding compositions and methods of use
|
|
AU2019272575A1
(en)
|
2018-05-21 |
2020-12-10 |
Compass Therapeutics Llc |
Compositions and methods for enhancing the killing of target cells by NK cells
|
|
WO2019226050A2
(en)
|
2018-05-24 |
2019-11-28 |
Wageningen Universiteit |
Novel viral anti-infective reagents
|
|
TWI869346B
(zh)
|
2018-05-30 |
2025-01-11 |
瑞士商諾華公司 |
Entpd2抗體、組合療法、及使用該等抗體和組合療法之方法
|
|
US20210214459A1
(en)
|
2018-05-31 |
2021-07-15 |
Novartis Ag |
Antibody molecules to cd73 and uses thereof
|
|
ES2996257T3
(en)
|
2018-05-31 |
2025-02-12 |
Alexion Pharma Inc |
Dosage and administration of anti-c5 antibodies for treatment of paroxysmal nocturnal hemoglobinuria (pnh) in pediatric patients
|
|
TWI848951B
(zh)
|
2018-06-01 |
2024-07-21 |
瑞士商諾華公司 |
針對bcma之結合分子及其用途
|
|
EP3802603A1
(en)
|
2018-06-04 |
2021-04-14 |
Alexion Pharmaceuticals, Inc. |
Dosage and administration of anti-c5 antibodies for treatment of atypical hemolytic uremic syndrome (ahus) in pediatric patients
|
|
WO2019234099A1
(en)
|
2018-06-06 |
2019-12-12 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for diagnosing, predicting the outcome and treating a patient suffering from heart failure with preserved ejection fraction
|
|
WO2019234221A1
(en)
|
2018-06-08 |
2019-12-12 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for stratification and treatment of a patient suffering from chronic lymphocytic leukemia
|
|
TWI848953B
(zh)
|
2018-06-09 |
2024-07-21 |
德商百靈佳殷格翰國際股份有限公司 |
針對癌症治療之多特異性結合蛋白
|
|
WO2019241315A1
(en)
|
2018-06-12 |
2019-12-19 |
Obsidian Therapeutics, Inc. |
Pde5 derived regulatory constructs and methods of use in immunotherapy
|
|
AU2019284911A1
(en)
|
2018-06-13 |
2020-12-17 |
Novartis Ag |
BCMA chimeric antigen receptors and uses thereof
|
|
BR112020025439A2
(pt)
|
2018-06-14 |
2021-03-16 |
Bluebird Bio, Inc. |
Receptores de antígenos quiméricos cd79a
|
|
KR20210022004A
(ko)
|
2018-06-18 |
2021-03-02 |
안위타 바이오사이언시스, 인코포레이티드 |
항-메소텔린 작제물 및 이의 용도
|
|
US20210238268A1
(en)
|
2018-06-19 |
2021-08-05 |
Atarga, Llc |
Antibody molecules to complement component 5 and uses thereof
|
|
US20230041197A1
(en)
|
2018-06-20 |
2023-02-09 |
Progenity, Inc. |
Treatment of a disease of the gastrointestinal tract with an immunomodulator
|
|
WO2019246317A1
(en)
|
2018-06-20 |
2019-12-26 |
Progenity, Inc. |
Treatment of a disease or condition in a tissue originating from the endoderm
|
|
WO2020006266A1
(en)
|
2018-06-28 |
2020-01-02 |
Alexion Pharmaceuticals, Inc. |
Methods of producing anti-c5 antibodies
|
|
MX2020013923A
(es)
|
2018-06-29 |
2021-03-29 |
Apitbio Inc |
Anticuerpos anti molécula de adhesión celular l1 (l1cam) y usos de estos.
|
|
WO2020001526A1
(zh)
|
2018-06-29 |
2020-01-02 |
苏州智核生物医药科技有限公司 |
Pd-l1结合多肽及其用途
|
|
AU2019297451A1
(en)
|
2018-07-03 |
2021-01-28 |
Marengo Therapeutics, Inc. |
Anti-TCR antibody molecules and uses thereof
|
|
CN118147029A
(zh)
|
2018-07-11 |
2024-06-07 |
阿克蒂姆治疗有限公司 |
工程化的免疫刺激性细菌菌株及其用途
|
|
TW202019474A
(zh)
|
2018-07-11 |
2020-06-01 |
美商西建公司 |
抗bcma嵌合抗原受體之用途
|
|
WO2020016160A1
(en)
|
2018-07-16 |
2020-01-23 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Method to treat neurological diseases
|
|
EP3823672A1
(en)
|
2018-07-19 |
2021-05-26 |
Institut National de la Santé et de la Recherche Médicale (INSERM) |
Combination for treating cancer
|
|
CN118994395A
(zh)
|
2018-07-20 |
2024-11-22 |
皮埃尔法布雷医药公司 |
Vista受体
|
|
WO2020021465A1
(en)
|
2018-07-25 |
2020-01-30 |
Advanced Accelerator Applications (Italy) S.R.L. |
Method of treatment of neuroendocrine tumors
|
|
ES2738926A1
(es)
|
2018-07-26 |
2020-01-27 |
Univ Zaragoza |
Granulisina, metodo de obtencion y usos
|
|
US20210186880A1
(en)
|
2018-08-03 |
2021-06-24 |
Brown University |
Oral formulations with increased uptake
|
|
EP3833442A2
(en)
|
2018-08-09 |
2021-06-16 |
Compass Therapeutics LLC |
Antibodies that bind cd277 and uses thereof
|
|
EP3833443A1
(en)
|
2018-08-09 |
2021-06-16 |
Compass Therapeutics LLC |
Antigen binding agents that bind cd277 and uses thereof
|
|
WO2020033925A2
(en)
|
2018-08-09 |
2020-02-13 |
Compass Therapeutics Llc |
Antibodies that bind cd277 and uses thereof
|
|
US12391957B2
(en)
|
2018-08-17 |
2025-08-19 |
Icahn School Of Medicine At Mount Sinai |
Recombinant Newcastle disease viruses and uses thereof for the prevention of RSV disease or human metapneumovirus disease
|
|
US11453893B2
(en)
|
2018-08-30 |
2022-09-27 |
California Institute Of Technology |
RNA-based delivery systems with levels of control
|
|
US11542305B2
(en)
|
2018-08-31 |
2023-01-03 |
California Institute Of Technology |
Synthetic protein circuits detecting signal transducer activity
|
|
ES3042082T3
(en)
|
2018-08-31 |
2025-11-18 |
Novartis Ag |
Methods of making chimeric antigen receptor-expressing cells
|
|
WO2020047449A2
(en)
|
2018-08-31 |
2020-03-05 |
Novartis Ag |
Methods of making chimeric antigen receptor-expressing cells
|
|
EP3848397A4
(en)
|
2018-09-04 |
2022-07-20 |
Nanjing Umab-Biopharma Co., Ltd. |
Fusion protein and its application in preparing medicine for treating tumor and/or viral infection
|
|
GB201814451D0
(en)
|
2018-09-05 |
2018-10-17 |
Valerie Nicholas Carl Kristoffer |
Methods
|
|
GB2576914A
(en)
|
2018-09-06 |
2020-03-11 |
Kymab Ltd |
Antigen-binding molecules comprising unpaired variable domains produced in mammals
|
|
EP3847196A4
(en)
|
2018-09-07 |
2023-01-04 |
ITabMed (HK) Limited |
BISPECIFIC ANTIGEN BINDING PROTEINS AND USES THEREOF
|
|
CN113195516B
(zh)
*
|
2018-09-11 |
2025-07-15 |
纳诺泰克生物技术公司 |
由特异性结合物识别的表位标签
|
|
US12195544B2
(en)
|
2018-09-21 |
2025-01-14 |
Harpoon Therapeutics, Inc. |
EGFR binding proteins and methods of use
|
|
US12473357B2
(en)
|
2018-09-25 |
2025-11-18 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of antagonists of Th17 cytokines for the treatment of bronchial remodeling in patients suffering from allergic asthma
|
|
EP3856771A4
(en)
|
2018-09-25 |
2022-06-29 |
Harpoon Therapeutics, Inc. |
Dll3 binding proteins and methods of use
|
|
CN113164777B
(zh)
|
2018-09-27 |
2024-12-13 |
马伦戈治疗公司 |
Csf1r/ccr2多特异性抗体
|
|
AU2019346335B2
(en)
|
2018-09-28 |
2024-07-25 |
Massachusetts Institute Of Technology |
Collagen-localized immunomodulatory molecules and methods thereof
|
|
WO2020070062A1
(en)
|
2018-10-01 |
2020-04-09 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of tim-3 inhibitors for the treatment of exacerbations in patients suffering from severe asthma
|
|
EP3860713A2
(en)
|
2018-10-03 |
2021-08-11 |
Staten Biotechnology B.V. |
Antibodies specific for human and cynomolgus apoc3 and methods of use thereof
|
|
EP3860653A1
(en)
|
2018-10-05 |
2021-08-11 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and systems for controlling the agonistic properties of antibody variable domains by light
|
|
WO2020076969A2
(en)
|
2018-10-10 |
2020-04-16 |
Tilos Therapeutics, Inc. |
Anti-lap antibody variants and uses thereof
|
|
UY38407A
(es)
|
2018-10-15 |
2020-05-29 |
Novartis Ag |
Anticuerpos estabilizadores de trem2
|
|
WO2020080941A1
(en)
|
2018-10-16 |
2020-04-23 |
Umc Utrecht Holding B.V. |
Anti- low-density lipoprotein receptor-related protein 5/6 antibodies
|
|
WO2020086742A1
(en)
|
2018-10-24 |
2020-04-30 |
Obsidian Therapeutics, Inc. |
Er tunable protein regulation
|
|
US12240893B2
(en)
|
2018-10-30 |
2025-03-04 |
Alexion Pharmaceuticals, Inc. |
Subcutaneous dosage and administration of anti-C5 antibodies for treatment of paroxysmal nocturnal hemoglobinuria (PNH)
|
|
US20220000893A1
(en)
|
2018-10-31 |
2022-01-06 |
|Nserm (Institut National De La Santé Et De La Recherche Médicale) |
Method for treating t-helper type 2 mediated disease
|
|
US12410225B2
(en)
|
2018-11-08 |
2025-09-09 |
Orionis Biosciences, Inc |
Modulation of dendritic cell lineages
|
|
MX2021005594A
(es)
|
2018-11-13 |
2021-10-22 |
Compass Therapeutics Llc |
Constructos multiespecificos de union contra moleculas de puntos de control y usos de los mismos.
|
|
GB201818477D0
(en)
|
2018-11-13 |
2018-12-26 |
Emstopa Ltd |
Tissue plasminogen activator antibodies and method of use thereof
|
|
WO2020118293A2
(en)
|
2018-12-07 |
2020-06-11 |
Georgia Tech Research Corporation |
Antibodies that bind to natively folded myocilin
|
|
MA54469A
(fr)
|
2018-12-13 |
2021-10-20 |
Surface Oncology Inc |
Anticorps anti-il-27 et leurs utilisations
|
|
WO2020120644A1
(en)
|
2018-12-13 |
2020-06-18 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
New anti tau svqivykpv epitope single domain antibody
|
|
JP2022513255A
(ja)
|
2018-12-20 |
2022-02-07 |
ノバルティス アーゲー |
HDM2-p53相互作用阻害剤とBCL2阻害剤との組み合わせ及び癌を処置するためのその使用
|
|
KR20210107062A
(ko)
|
2018-12-21 |
2021-08-31 |
오제 이뮈노테라프틱스 |
이작용성 항-PD-1/SIRPα 분자
|
|
CA3123338A1
(en)
|
2018-12-21 |
2020-06-25 |
Ose Immunotherapeutics |
Bifunctional anti-pd-1/il-7 molecule
|
|
WO2020130838A2
(en)
|
2018-12-21 |
2020-06-25 |
Qvq Holding B.V. |
Antibodies for preventing or treating candidiasis
|
|
CA3122899A1
(en)
|
2018-12-21 |
2020-06-25 |
Ose Immunotherapeutics |
Bifunctional molecule directed against human pd-1
|
|
JP2022515960A
(ja)
|
2019-01-02 |
2022-02-24 |
ニューラクル サイエンス カンパニー リミテッド |
抗配列類似性19を持つファミリー、メンバーa5抗体及びその使用方法
|
|
KR20220008253A
(ko)
|
2019-01-03 |
2022-01-20 |
엥스띠뛰 나씨오날 드 라 쌍떼 에 드 라 흐쉐르슈 메디깔 (인쎄름) |
암을 앓는 대상에서 cd8+ t 세포 의존성 면역 반응을 향상시키기 위한 방법 및 약학적 조성물
|
|
EP3908602A1
(en)
|
2019-01-07 |
2021-11-17 |
Bactolife ApS |
Pathogen binding proteins
|
|
EP3908653A4
(en)
|
2019-01-10 |
2022-11-02 |
California Institute of Technology |
A synthetic system for tunable thresholding of protein signals
|
|
JP7645185B2
(ja)
|
2019-01-15 |
2025-03-13 |
アンスティチュート、ナシオナル、ドゥ、ラ、サンテ、エ、ドゥ、ラ、ルシェルシュ、メディカル |
変異したインターロイキン-34(il-34)ポリペプチドおよび治療におけるその使用
|
|
WO2020148349A1
(en)
|
2019-01-16 |
2020-07-23 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Variants of erythroferrone and their use
|
|
US20220111047A1
(en)
|
2019-01-16 |
2022-04-14 |
Compass Therapeutics Llc |
Formulations of antibodies that bind human cd137 and uses thereof
|
|
TWI756621B
(zh)
|
2019-01-25 |
2022-03-01 |
大陸商信達生物製藥(蘇州)有限公司 |
新型雙特異性抗體分子以及同時結合pd-l1和lag-3的雙特異性抗體
|
|
GB201901608D0
(en)
|
2019-02-06 |
2019-03-27 |
Vib Vzw |
Vaccine adjuvant conjugates
|
|
WO2020165374A1
(en)
|
2019-02-14 |
2020-08-20 |
Ose Immunotherapeutics |
Bifunctional molecule comprising il-15ra
|
|
US10871640B2
(en)
|
2019-02-15 |
2020-12-22 |
Perkinelmer Cellular Technologies Germany Gmbh |
Methods and systems for automated imaging of three-dimensional objects
|
|
CA3129317A1
(en)
|
2019-02-15 |
2020-08-20 |
Integral Molecular, Inc. |
Antibodies comprising a common light chain and uses thereof
|
|
KR20210128443A
(ko)
|
2019-02-15 |
2021-10-26 |
인테그럴 몰큘러 인코포레이티드 |
클라우딘 6 항체 및 이의 용도
|
|
CA3131016A1
(en)
|
2019-02-21 |
2020-08-27 |
Andreas Loew |
Multifunctional molecules that bind to calreticulin and uses thereof
|
|
CN119661722A
(zh)
|
2019-02-21 |
2025-03-21 |
马伦戈治疗公司 |
结合t细胞相关癌细胞的多功能分子及其用途
|
|
WO2020169707A1
(en)
|
2019-02-21 |
2020-08-27 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Foxo1 inhibitor for use in the treatment of latent virus infection
|
|
GB2598218B
(en)
|
2019-02-21 |
2024-05-08 |
Marengo Therapeutics Inc |
Anti-TCR antibody molecules and uses thereof
|
|
WO2020172598A1
(en)
|
2019-02-21 |
2020-08-27 |
Elstar Therapeutics, Inc. |
Multifunctional molecules that bind to t cells and uses thereof to treat autoimmune disorders
|
|
EP3927747A1
(en)
|
2019-02-21 |
2021-12-29 |
Marengo Therapeutics, Inc. |
Antibody molecules that bind to nkp30 and uses thereof
|
|
US20220088075A1
(en)
|
2019-02-22 |
2022-03-24 |
The Trustees Of The University Of Pennsylvania |
Combination therapies of egfrviii chimeric antigen receptors and pd-1 inhibitors
|
|
ES2978570T3
(es)
|
2019-02-26 |
2024-09-16 |
Inspirna Inc |
Anticuerpos anti-MERTK de alta afinidad y sus usos
|
|
EP3930757A1
(en)
|
2019-03-01 |
2022-01-05 |
President And Fellows Of Harvard College |
Methods and compositions for protein delivery
|
|
EP3935084B1
(en)
|
2019-03-08 |
2024-06-12 |
LinXis B.V. |
Internalizing binding molecules targeting receptors involved in cell proliferation or cell differentiation
|
|
KR20210149251A
(ko)
|
2019-03-08 |
2021-12-08 |
옵시디안 테라퓨틱스, 인크. |
조율가능한 조절을 위한 인간 탄산 무수화효소 2 조성물 및 방법
|
|
WO2020193740A1
(en)
|
2019-03-28 |
2020-10-01 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
New strategy for treating pancreatic cancer
|
|
WO2020198731A2
(en)
|
2019-03-28 |
2020-10-01 |
Danisco Us Inc |
Engineered antibodies
|
|
PH12021552414A1
(en)
|
2019-03-29 |
2022-07-25 |
Atarga Llc |
Anti fgf23 antibody
|
|
US12291562B2
(en)
|
2019-04-01 |
2025-05-06 |
Rush University Medical Center |
Reagents and assays using modified integrin domains
|
|
WO2020205409A1
(en)
|
2019-04-03 |
2020-10-08 |
President And Fellows Of Harvard College |
Ionic liquids for drug delivery
|
|
EP3947472A4
(en)
|
2019-04-04 |
2023-02-22 |
Vanderbilt University |
THERAPEUTIC ANTIBODIES FOR THE TREATMENT OF LUNG CANCER
|
|
WO2020208082A1
(en)
|
2019-04-09 |
2020-10-15 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Method for treating cmv related diseases
|
|
WO2020210678A1
(en)
|
2019-04-12 |
2020-10-15 |
Novartis Ag |
Methods of making chimeric antigen receptor-expressing cells
|
|
SG11202111980QA
(en)
|
2019-04-29 |
2021-11-29 |
Confo Therapeutics N V |
Screening methods and assays for use with transmembrane proteins, in particular with gpcrs
|
|
EP3962599A1
(en)
|
2019-04-30 |
2022-03-09 |
Vib Vzw |
Cystic fibrosis transmembrane conductance regulator stabilizing agents
|
|
US20200363400A1
(en)
|
2019-05-13 |
2020-11-19 |
Regeneron Pharmaceuticals, Inc. |
Competitive Ligand Binding Assays
|
|
US12146160B2
(en)
|
2019-05-14 |
2024-11-19 |
Institut National De La Sante Et De La Recherche Medicale (Inserm) |
Regulatory T cells targeted by lymphotoxin alpha blocking agent and uses thereof
|
|
KR20220008866A
(ko)
|
2019-05-14 |
2022-01-21 |
하푼 테라퓨틱스, 인크. |
EpCAM 결합 단백질 및 사용 방법
|
|
US20220227859A1
(en)
|
2019-05-16 |
2022-07-21 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Method to treat type 2 inflammation or mast-cell dependent disease
|
|
CA3140142A1
(en)
|
2019-05-21 |
2020-11-26 |
Novartis Ag |
Trispecific binding molecules against bcma and uses thereof
|
|
US12037378B2
(en)
|
2019-05-21 |
2024-07-16 |
Novartis Ag |
Variant CD58 domains and uses thereof
|
|
BR112021023048A2
(pt)
|
2019-05-21 |
2022-04-19 |
Novartis Ag |
Moléculas de ligação a cd19 e usos das mesmas
|
|
CN114206935B
(zh)
|
2019-05-24 |
2024-01-12 |
三优生物医药(上海)有限公司 |
新型cldn18.2结合分子
|
|
US20220220197A1
(en)
|
2019-05-28 |
2022-07-14 |
Vib Vzw |
Cancer Treatment by Targeting Plexins in the Immune Compartment
|
|
WO2020239934A1
(en)
|
2019-05-28 |
2020-12-03 |
Vib Vzw |
Cd8+ t-cells lacking plexins and their application in cancer treatment
|
|
GB2584441A
(en)
|
2019-06-03 |
2020-12-09 |
Fenomark Diagnostics Ab |
Medical uses, methods and uses
|
|
JP2022535553A
(ja)
|
2019-06-04 |
2022-08-09 |
シャンハイ、ケンパーソー、バイオテクノロジー、カンパニー、リミテッド |
抗ceacam5モノクローナル抗体、その作製方法およびその使用
|
|
EP3983437A1
(en)
|
2019-06-12 |
2022-04-20 |
Novartis AG |
Natriuretic peptide receptor 1 antibodies and methods of use
|
|
US12338291B2
(en)
|
2019-06-17 |
2025-06-24 |
Visterra, Inc. |
Humanized antibody molecules to CD138 and uses thereof
|
|
JP7685957B2
(ja)
|
2019-06-20 |
2025-05-30 |
アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル |
プロテアーゼネキシン-1に対する立体構造的な単一ドメイン抗体及びその使用
|
|
MX2021015762A
(es)
|
2019-06-21 |
2022-04-18 |
Sorriso Pharmaceuticals Inc |
Composiciones.
|
|
EP3986931A1
(en)
|
2019-06-21 |
2022-04-27 |
Sorriso Pharmaceuticals, Inc. |
Polypeptides
|
|
AU2020294980A1
(en)
|
2019-06-21 |
2022-02-17 |
Sorriso Pharmaceuticals, Inc. |
Polypeptides
|
|
EP3990491A1
(en)
|
2019-06-26 |
2022-05-04 |
Massachusetts Institute of Technology |
Immunomodulatory fusion protein-metal hydroxide complexes and methods thereof
|
|
CN114466863A
(zh)
|
2019-07-01 |
2022-05-10 |
苏州康宁杰瑞生物科技有限公司 |
百日咳毒素结合蛋白
|
|
WO2021001539A1
(en)
|
2019-07-04 |
2021-01-07 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
New strategy to detect and treat eosinophilic fasciitis
|
|
CA3145345A1
(en)
|
2019-07-15 |
2021-01-21 |
Intervet International B.V. |
Caninized antibodies against canine ctla-4
|
|
PH12022550165A1
(en)
|
2019-07-26 |
2023-05-08 |
Visterra Inc |
Interleukin-2 agents and uses thereof
|
|
WO2021025556A1
(en)
|
2019-08-05 |
2021-02-11 |
Stichting Vu |
Identification and elimination of hcmv-infected cells
|
|
PH12022550460A1
(en)
|
2019-08-30 |
2023-02-27 |
Agenus Inc |
Anti-cd96 antibodies and methods of use thereof
|
|
CN114616250B
(zh)
|
2019-09-04 |
2024-11-08 |
豪夫迈·罗氏有限公司 |
Cd8结合剂及其用途
|
|
WO2021044012A1
(en)
|
2019-09-05 |
2021-03-11 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Method of treatment and pronostic of acute myeloid leukemia
|
|
US20220348937A1
(en)
|
2019-09-06 |
2022-11-03 |
Obsidian Therapeutics, Inc. |
Compositions and methods for dhfr tunable protein regulation
|
|
JP2022548484A
(ja)
|
2019-09-16 |
2022-11-21 |
サーフィス オンコロジー インコーポレイテッド |
抗cd39抗体の組成物及び方法
|
|
US20220348651A1
(en)
|
2019-09-18 |
2022-11-03 |
Novartis Ag |
Entpd2 antibodies, combination therapies, and methods of using the antibodies and combination therapies
|
|
TW202124446A
(zh)
|
2019-09-18 |
2021-07-01 |
瑞士商諾華公司 |
與entpd2抗體之組合療法
|
|
TW202521984A
(zh)
|
2019-09-25 |
2025-06-01 |
美商表面腫瘤學有限責任公司 |
抗il-27抗體及其用途
|
|
TW202126295A
(zh)
|
2019-09-27 |
2021-07-16 |
大陸商江蘇挪貝肽醫藥科技有限公司 |
一種治療心境障礙的方法
|
|
US20220290151A1
(en)
|
2019-09-27 |
2022-09-15 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of müllerian inhibiting substance inhibitors for treating cancer
|
|
TWI878355B
(zh)
|
2019-10-02 |
2025-04-01 |
德商百靈佳殷格翰國際股份有限公司 |
用於癌症治療之多重專一性結合蛋白
|
|
EP3799881A1
(en)
|
2019-10-04 |
2021-04-07 |
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. |
Single domain antibodies specifically binding globo - series glycans
|
|
CN114786679A
(zh)
|
2019-10-21 |
2022-07-22 |
诺华股份有限公司 |
具有维奈托克和tim-3抑制剂的组合疗法
|
|
WO2021078786A1
(en)
|
2019-10-21 |
2021-04-29 |
Vib Vzw |
Nanodisc-specific antigen-binding chimeric proteins
|
|
CN114786680A
(zh)
|
2019-10-21 |
2022-07-22 |
诺华股份有限公司 |
Tim-3抑制剂及其用途
|
|
US11459389B2
(en)
|
2019-10-24 |
2022-10-04 |
Massachusetts Institute Of Technology |
Monoclonal antibodies that bind human CD161
|
|
WO2021086948A1
(en)
|
2019-10-28 |
2021-05-06 |
Georgia Tech Research Corporation |
Mrna-encoded antibodies for contraception
|
|
US20240148901A1
(en)
|
2019-10-28 |
2024-05-09 |
Georgia Tech Research Corporation |
Compositions and methods for prophylaxis of hiv
|
|
US20210128619A1
(en)
|
2019-11-05 |
2021-05-06 |
Celgene Corporation |
Uses of anti-bcma chimeric antigen receptors
|
|
BR112022009087A2
(pt)
|
2019-11-11 |
2022-07-26 |
Ibi Ag Innovative Bio Insecticides Ltd |
Nanocorpos para controle de insetos e usos dos mesmos
|
|
EP4058578A2
(en)
|
2019-11-12 |
2022-09-21 |
Actym Therapeutics, Inc. |
Immunostimulatory bacteria delivery platforms and their use for delivery of therapeutic products
|
|
JP2023503899A
(ja)
|
2019-11-22 |
2023-02-01 |
プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ |
薬物送達のためのイオン液体
|
|
CA3163104A1
(en)
|
2019-11-26 |
2021-06-03 |
Novartis Ag |
Chimeric antigen receptors and uses thereof
|
|
WO2021105391A1
(en)
|
2019-11-27 |
2021-06-03 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Combination comprising nupr1 inhibitors to treat cancer
|
|
WO2021105438A1
(en)
|
2019-11-27 |
2021-06-03 |
Vib Vzw |
Positive allosteric modulators of the calcium-sensing receptor
|
|
WO2021105384A1
(en)
|
2019-11-27 |
2021-06-03 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Targeting the nls region of nupr1 protein to treat cancer
|
|
EP4069372A1
(en)
|
2019-12-05 |
2022-10-12 |
Ose Immunotherapeutics |
Anti-clec-1a antibodies and antigen-binding fragment thereof
|
|
US11897950B2
(en)
|
2019-12-06 |
2024-02-13 |
Augusta University Research Institute, Inc. |
Osteopontin monoclonal antibodies
|
|
CN114981300B
(zh)
|
2019-12-06 |
2025-10-31 |
艾伯霖克斯公司 |
包含靶向TNFα和IL-23的免疫球蛋白单个可变结构域的多肽
|
|
CA3163764A1
(en)
|
2019-12-06 |
2021-06-10 |
Ablynx Nv |
Polypeptides comprising immunoglobulin single variable domains targeting tnfa and ox40l
|
|
AU2020400938A1
(en)
|
2019-12-09 |
2022-07-28 |
Ablynx Nv |
Polypeptides comprising immunoglobulin single variable domains targeting IL-13 and TSLP
|
|
US20230040928A1
(en)
|
2019-12-09 |
2023-02-09 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Antibodies having specificity to her4 and uses thereof
|
|
GB201918279D0
(en)
|
2019-12-12 |
2020-01-29 |
Vib Vzw |
Glycosylated single chain immunoglobulin domains
|
|
TW202136287A
(zh)
|
2019-12-17 |
2021-10-01 |
法商Ose免疫治療公司 |
包含il-7變體之雙官能分子
|
|
JP2023508023A
(ja)
|
2019-12-20 |
2023-02-28 |
ハドソン インスティチュート オブ メディカル リサーチ |
Cxcl10結合タンパク質及びその使用
|
|
AU2020407124A1
(en)
|
2019-12-20 |
2022-07-21 |
Momenta Pharmaceuticals, Inc. |
Antibodies against integrin alpha 11 beta 1
|
|
EP4077372A1
(en)
|
2019-12-20 |
2022-10-26 |
Vib Vzw |
Nanobody exchange chromatography
|
|
MX2022007759A
(es)
|
2019-12-20 |
2022-07-19 |
Novartis Ag |
Combinacion del anticuerpo anti tim-3 mbg453 y anticuerpo anti tgf-beta nis793, con o sin decitabina o el anticuerpo anti pd-1 spartalizumab, para el tratamiento de mielofibrosis y sindrome mielodisplasico.
|
|
WO2021138407A2
(en)
|
2020-01-03 |
2021-07-08 |
Marengo Therapeutics, Inc. |
Multifunctional molecules that bind to cd33 and uses thereof
|
|
GB2609554B
(en)
|
2020-01-03 |
2025-08-20 |
Marengo Therapeutics Inc |
Anti-TCR antibody molecules and uses thereof
|
|
TWI845803B
(zh)
|
2020-01-06 |
2024-06-21 |
美商法西尼克斯股份有限公司 |
抗ccr8抗體及其用途
|
|
WO2021140205A1
(en)
|
2020-01-10 |
2021-07-15 |
Confo Therapeutics N.V. |
Methods for generating antibodies and antibody fragments and libraries comprising same
|
|
TWI869528B
(zh)
|
2020-01-13 |
2025-01-11 |
美商威特拉公司 |
C5ar1抗體分子及其用途
|
|
EP4090335A1
(en)
|
2020-01-17 |
2022-11-23 |
Novartis AG |
Combination comprising a tim-3 inhibitor and a hypomethylating agent for use in treating myelodysplastic syndrome or chronic myelomonocytic leukemia
|
|
MX2022008845A
(es)
|
2020-01-17 |
2022-08-10 |
Univ Gent |
Anticuerpos de dominio unico de inmunoglobulina para la entrega de vacunas a traves de la mucosa.
|
|
WO2021156490A2
(en)
|
2020-02-06 |
2021-08-12 |
Vib Vzw |
Corona virus binders
|
|
EP4104187A1
(en)
|
2020-02-14 |
2022-12-21 |
Novartis AG |
Method of predicting response to chimeric antigen receptor therapy
|
|
IL295448A
(en)
|
2020-02-21 |
2022-10-01 |
Harpoon Therapeutics Inc |
flt3 binding proteins and methods of use
|
|
MX2022010461A
(es)
|
2020-02-24 |
2022-12-13 |
Immatics Us Inc |
Metodos para expandir linfocitos t para el tratamiento de cancer y neoplasias malignas asociadas.
|
|
JP2023514654A
(ja)
|
2020-02-25 |
2023-04-06 |
ブイアイビー ブイゼットダブリュ |
ロイシンリッチリピートキナーゼ2のアロステリック調節因子
|
|
WO2021173674A1
(en)
|
2020-02-26 |
2021-09-02 |
A2 Biotherapeutics, Inc. |
Polypeptides targeting mage-a3 peptide-mhc complexes and methods of use thereof
|
|
BR112022016633A2
(pt)
|
2020-02-27 |
2022-12-13 |
Novartis Ag |
Métodos para produzir células que expressam receptor de antígeno quimérico
|
|
US20230256017A1
(en)
|
2020-02-27 |
2023-08-17 |
Jennifer Brogdon |
Methods of making chimeric antigen receptor-expressing cells
|
|
CA3173527A1
(en)
|
2020-03-10 |
2021-09-16 |
Massachusetts Institute Of Technology |
Methods for generating engineered memory-like nk cells and compositions thereof
|
|
JP2023517889A
(ja)
|
2020-03-10 |
2023-04-27 |
マサチューセッツ インスティテュート オブ テクノロジー |
NPM1c陽性がんの免疫療法のための組成物および方法
|
|
DE102020111571A1
(de)
|
2020-03-11 |
2021-09-16 |
Immatics US, Inc. |
Wpre-mutantenkonstrukte, zusammensetzungen und zugehörige verfahren
|
|
CA3175140A1
(en)
|
2020-03-12 |
2021-09-16 |
Immune-Onc Therapeutics, Inc. |
Novel anti-lilrb4 antibodies and derivative products
|
|
CN115003333A
(zh)
|
2020-03-13 |
2022-09-02 |
江苏恒瑞医药股份有限公司 |
Pvrig结合蛋白及其医药用途
|
|
US11365239B2
(en)
|
2020-03-20 |
2022-06-21 |
Tsb Therapeutics (Beijing) Co., Ltd. |
Anti-SARS-COV-2 antibodies and uses thereof
|
|
IL296330A
(en)
|
2020-03-20 |
2022-11-01 |
Glaxosmithkline Ip Dev Ltd |
Method for detecting polysorbates
|
|
CN116249549A
(zh)
|
2020-03-27 |
2023-06-09 |
诺华股份有限公司 |
用于治疗增殖性疾病和自身免疫病症的双特异性组合疗法
|
|
EP4126971A1
(en)
|
2020-03-30 |
2023-02-08 |
Ablynx N.V. |
Method for the production and purification of multivalent immunoglobulin single variable domains
|
|
CN113461817B
(zh)
|
2020-03-31 |
2025-04-18 |
苏州泽璟生物制药股份有限公司 |
一种抗人cd47抗体及其抗原结合片段、制备方法和应用
|
|
AU2021250446A1
(en)
|
2020-03-31 |
2022-11-17 |
Biotalys NV |
Anti-fungal polypeptides
|
|
CN116710146A
(zh)
|
2020-04-03 |
2023-09-05 |
威特拉公司 |
抗体分子-药物偶联物及其用途
|
|
EP4132971A1
(en)
|
2020-04-09 |
2023-02-15 |
Merck Sharp & Dohme LLC |
Affinity matured anti-lap antibodies and uses thereof
|
|
MX2022012752A
(es)
|
2020-04-15 |
2023-01-16 |
Voyager Therapeutics Inc |
Compuestos de union a tau.
|
|
US20230416344A1
(en)
|
2020-04-16 |
2023-12-28 |
Alexion Pharmaceuticals, Inc. |
Methods for treating a complement mediated disorder caused by viruses
|
|
US20230279115A1
(en)
|
2020-04-22 |
2023-09-07 |
Mabwell (shanghai) Bioscience Co., Ltd. |
Single variable domain antibody targeting human programmed death ligand 1 (pd-l1) and derivative thereof
|
|
KR20230028242A
(ko)
|
2020-04-24 |
2023-02-28 |
마렝고 테라퓨틱스, 인크. |
T 세포 관련 암 세포에 결합하는 다중기능성 분자 및 그것의 용도
|
|
CN116457368A
(zh)
|
2020-05-01 |
2023-07-18 |
匹兹堡大学联邦高等教育系统 |
用于鉴定纳米抗体和纳米抗体亲和力的组合物和方法
|
|
CA3181963A1
(en)
|
2020-05-04 |
2021-11-11 |
Immunorizon Ltd. |
Precursor tri-specific antibody constructs and methods of use thereof
|
|
CA3180683A1
(en)
|
2020-05-12 |
2021-11-18 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
New method to treat cutaneous t-cell lymphomas and tfh derived lymphomas
|
|
WO2021229104A1
(en)
|
2020-05-15 |
2021-11-18 |
Université de Liège |
Anti-cd38 single-domain antibodies in disease monitoring and treatment
|
|
WO2021236658A1
(en)
|
2020-05-19 |
2021-11-25 |
Boehringer Ingelheim International Gmbh |
Binding molecules for the treatment of cancer
|
|
EP4153192B8
(en)
|
2020-05-19 |
2024-09-04 |
Institut Curie |
Antagonist of cd44/hyaluronic acid pathway for use in a method for the treatment of cytokine release syndrome
|
|
EP3916088A1
(en)
|
2020-05-28 |
2021-12-01 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Fusion proteins comprising the sars-cov-2 3clpro catalytic domain and their uses for screening anti-sars-cov-2 agents
|
|
CA3180060A1
(en)
|
2020-05-29 |
2021-12-02 |
Zongmin ZHAO |
Living cells engineered with polyphenol-functionalized biologically active nanocomplexes
|
|
CN111647077B
(zh)
|
2020-06-02 |
2021-02-09 |
深圳市因诺赛生物科技有限公司 |
新型冠状病毒(sars-cov-2)刺突蛋白结合分子及其应用
|
|
CR20220611A
(es)
|
2020-06-02 |
2023-06-07 |
Arcus Biosciences Inc |
Anticuerpos anti-tigit
|
|
US20230332104A1
(en)
|
2020-06-11 |
2023-10-19 |
Novartis Ag |
Zbtb32 inhibitors and uses thereof
|
|
CN116157510A
(zh)
|
2020-06-17 |
2023-05-23 |
詹森生物科技公司 |
用于制造多能干细胞的材料和方法
|
|
WO2021255204A1
(en)
|
2020-06-18 |
2021-12-23 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
New strategy for treating pancreatic cancer
|
|
JP2023531722A
(ja)
|
2020-06-24 |
2023-07-25 |
ビステラ, インコーポレイテッド |
Aprilに対する抗体分子およびその使用
|
|
US20230265211A1
(en)
|
2020-06-29 |
2023-08-24 |
Inserm (Institut National De La Santé Et De Ls Recherche Médicale) |
Anti-protein s single-domain antibodies and polypeptides comprising thereof
|
|
WO2022003156A1
(en)
|
2020-07-02 |
2022-01-06 |
Oncurious Nv |
Ccr8 non-blocking binders
|
|
WO2022006219A2
(en)
|
2020-07-02 |
2022-01-06 |
Trustees Of Tufts College |
Vhh polypeptides that bind to clostridium difficile toxin b and methods of use thereof
|
|
AU2021302199A1
(en)
|
2020-07-03 |
2023-02-23 |
Suzhou Alphamab Co., Ltd. |
Coagulation factor XI (FXI) binding protein
|
|
PH12023550015A1
(en)
|
2020-07-16 |
2024-03-11 |
Novartis Ag |
Anti-betacellulin antibodies, fragments thereof, and multi-specific binding molecules
|
|
US20240209089A1
(en)
|
2020-07-21 |
2024-06-27 |
Suzhou Smartnuclide Biopharmaceutical Co., Ltd. |
Cd8 binding polypeptide and use thereof
|
|
JP2023535024A
(ja)
|
2020-07-23 |
2023-08-15 |
オター プロシーナ リミテッド |
抗aベータ抗体
|
|
WO2022026592A2
(en)
|
2020-07-28 |
2022-02-03 |
Celltas Bio, Inc. |
Antibody molecules to coronavirus and uses thereof
|
|
EP4189061A1
(en)
|
2020-07-31 |
2023-06-07 |
Biotalys NV |
Methods of increasing recombinant protein yields
|
|
WO2022035722A1
(en)
|
2020-08-10 |
2022-02-17 |
Janssen Biotech, Inc. |
Materials and methods for producing bioengineered virus specific lymphocytes
|
|
EP4196139A2
(en)
|
2020-08-12 |
2023-06-21 |
Actym Therapeutics, Inc. |
Immunostimulatory bacteria-based vaccines, therapeutics, and rna delivery platforms
|
|
US20220056411A1
(en)
|
2020-08-21 |
2022-02-24 |
Immatics US, Inc. |
Methods for isolating cd8+ selected t cells
|
|
AU2021331075A1
(en)
|
2020-08-26 |
2023-04-06 |
Marengo Therapeutics, Inc. |
Multifunctional molecules that bind to calreticulin and uses thereof
|
|
CA3190766A1
(en)
|
2020-08-26 |
2022-03-03 |
Marengo Therapeutics, Inc. |
Antibody molecules that bind to nkp30 and uses thereof
|
|
GB2616354A
(en)
|
2020-08-26 |
2023-09-06 |
Marengo Therapeutics Inc |
Methods of detecting TRBC1 or TRBC2
|
|
EP4204020A1
(en)
|
2020-08-31 |
2023-07-05 |
Advanced Accelerator Applications International S.A. |
Method of treating psma-expressing cancers
|
|
US20230321285A1
(en)
|
2020-08-31 |
2023-10-12 |
Advanced Accelerator Applications International Sa |
Method of treating psma-expressing cancers
|
|
CA3195367A1
(en)
|
2020-09-14 |
2022-03-17 |
Vor Biopharma Inc. |
Single domain antibodies against cd33
|
|
WO2022060806A1
(en)
|
2020-09-16 |
2022-03-24 |
Obsidian Therapeutics, Inc. |
Compositions and methods for expression of anti-bcma chimeric antigen receptors with small molecule-regulated il15 in t cells
|
|
US20240325562A1
(en)
|
2020-09-16 |
2024-10-03 |
Linxis B.V. |
Internalizing binding molecules
|
|
WO2022063947A1
(en)
|
2020-09-24 |
2022-03-31 |
Vib Vzw |
Combination of p2y6 inhibitors and immune checkpoint inhibitors
|
|
WO2022063957A1
(en)
|
2020-09-24 |
2022-03-31 |
Vib Vzw |
Biomarker for anti-tumor therapy
|
|
CA3195687A1
(en)
|
2020-09-25 |
2022-03-31 |
Ablynx Nv |
Polypeptides comprising immunoglobulin single variable domains targeting il-13 and ox40l
|
|
JP2023545520A
(ja)
|
2020-10-14 |
2023-10-30 |
ビリジアン セラピューティクス, インコーポレイテッド |
甲状腺眼疾患を治療するための組成物及び方法
|
|
WO2022084399A1
(en)
|
2020-10-21 |
2022-04-28 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
C-terminal sparc fragments for treating cancer
|
|
AR123862A1
(es)
|
2020-10-21 |
2023-01-18 |
Boehringer Ingelheim Int |
Moléculas de unión biespecíficas anti-vegf y anti-trkb para el tratamiento de enfermedades oculares
|
|
US20230398149A1
(en)
|
2020-11-04 |
2023-12-14 |
Celgene Corporation |
Car t cell therapy in patients who have had prior anti-cancer alkylator therapy
|
|
AU2021373366A1
(en)
|
2020-11-06 |
2023-06-01 |
Novartis Ag |
Cd19 binding molecules and uses thereof
|
|
CN116390933A
(zh)
|
2020-11-06 |
2023-07-04 |
诺华股份有限公司 |
治疗b细胞恶性肿瘤的抗cd19剂和b细胞靶向剂组合疗法
|
|
CN112480248B
(zh)
|
2020-11-24 |
2023-05-05 |
三优生物医药(上海)有限公司 |
与cld18a2特异性结合的分子
|
|
WO2022117569A1
(en)
|
2020-12-02 |
2022-06-09 |
Oncurious Nv |
A ccr8 antagonist antibody in combination with a lymphotoxin beta receptor agonist antibody in therapy against cancer
|
|
JP2024508207A
(ja)
|
2020-12-02 |
2024-02-26 |
ブイアイビー ブイゼットダブリュ |
がんに対する組み合わせ治療におけるltbrアゴニスト
|
|
WO2022120160A1
(en)
|
2020-12-04 |
2022-06-09 |
Celgene Corporation |
Uses of chimeric antigen receptor (car) t-cell therapies in combination with inhibitors of inflammation-related soluble factors
|
|
PH12023500013A1
(en)
|
2020-12-04 |
2024-03-11 |
Tidal Therapeutics Inc |
Ionizable cationic lipids and lipi nanoparticles, and methods of synthesis and use thereof
|
|
EP4255466A1
(en)
|
2020-12-04 |
2023-10-11 |
Visterra, Inc. |
Methods of using interleukin-2 agents
|
|
WO2022130182A1
(en)
|
2020-12-14 |
2022-06-23 |
Novartis Ag |
Reversal binding agents for anti-natriuretic peptide receptor 1 (npr1) antibodies and uses thereof
|
|
IL303745A
(en)
|
2020-12-17 |
2023-08-01 |
Ose Immunotherapeutics |
Bifunctional anti-pd1/il-7 molecules
|
|
WO2022129637A1
(en)
|
2020-12-18 |
2022-06-23 |
Ablynx Nv |
T cell recruiting polypeptides based on tcr alpha/beta reactivity
|
|
IL303783A
(en)
|
2020-12-18 |
2023-08-01 |
Sanofi Sa |
Polypeptides comprising immunoglobulin single variable domains targeting glypican-3 and t cell receptor
|
|
KR20230123497A
(ko)
|
2020-12-18 |
2023-08-23 |
아블린쓰 엔.브이. |
IL-6 및 TNF-α를 표적화하는 면역글로불린 단일 가변도메인을 포함하는 폴리펩티드
|
|
GB202020502D0
(en)
|
2020-12-23 |
2021-02-03 |
Vib Vzw |
Antibody composistion for treatment of corona virus infection
|
|
WO2022136650A1
(en)
|
2020-12-24 |
2022-06-30 |
Oncurious Nv |
Murine cross-reactive human ccr8 binders
|
|
EP4267618A1
(en)
|
2020-12-24 |
2023-11-01 |
Vib Vzw |
Non-blocking human ccr8 binders
|
|
EP4267617A1
(en)
|
2020-12-24 |
2023-11-01 |
Vib Vzw |
Human ccr8 binders
|
|
AU2022211021A1
(en)
|
2021-01-20 |
2023-08-03 |
Visterra, Inc. |
Interleukin-2 mutants and uses thereof
|
|
GB2603166A
(en)
|
2021-01-29 |
2022-08-03 |
Thelper As |
Therapeutic and Diagnostic Agents and Uses Thereof
|
|
JP2024505049A
(ja)
|
2021-01-29 |
2024-02-02 |
ノバルティス アーゲー |
抗cd73及び抗entpd2抗体のための投与方式並びにその使用
|
|
IL304904A
(en)
|
2021-02-01 |
2023-10-01 |
St Phi Therapeutics Co Ltd |
Target protein degradation system and its use
|
|
CN117794566A
(zh)
|
2021-02-05 |
2024-03-29 |
Vib研究所 |
沙贝病毒结合剂
|
|
WO2022170063A1
(en)
|
2021-02-05 |
2022-08-11 |
Salubris Biotherapeutics, Inc. |
Il-15 fusion proteins and methods of making and using same
|
|
KR20230141853A
(ko)
|
2021-02-05 |
2023-10-10 |
브이아이비 브이지더블유 |
사베코바이러스 결합제
|
|
WO2022171777A1
(en)
|
2021-02-12 |
2022-08-18 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Method for prognosis and treating a patient suffering from cancer
|
|
CA3211257A1
(en)
|
2021-02-17 |
2022-08-25 |
Vib Vzw |
Inhibition of slc4a4 in the treatment of cancer
|
|
BR112023016706A2
(pt)
|
2021-02-19 |
2023-10-31 |
Seoul Nat Univ R&Db Foundation |
Anticorpo ou um fragmento de ligação ao antígeno do mesmo, molécula de ácido nucleico, métodos para produzir um anticorpo ou um fragmento de ligação ao antígeno do mesmo e para detectar agrupamento de diferenciação 47 ou determinar uma quantidade de agrupamento de diferenciação 47 em uma amostra, e, uso do anticorpo ou de um fragmento de ligação ao antígeno do mesmo
|
|
JP7773239B2
(ja)
|
2021-02-19 |
2025-11-19 |
シャペロン インク. |
Pd-l1及びcd47に対する二重特異性単一ドメイン抗体及びその用途
|
|
CA3209052A1
(en)
|
2021-02-19 |
2022-08-25 |
Rafael Cristian CASELLAS |
Single domain antibodies that neutralize sars-cov-2
|
|
AU2022222994B2
(en)
|
2021-02-19 |
2025-11-27 |
Shaperon Inc. |
Single domain antibody against cd47 and use thereof
|
|
EP4294516A1
(en)
|
2021-02-19 |
2023-12-27 |
Vib Vzw |
Cation-independent mannose-6-phosphate receptor binders
|
|
WO2022195551A1
(en)
|
2021-03-18 |
2022-09-22 |
Novartis Ag |
Biomarkers for cancer and methods of use thereof
|
|
WO2022199804A1
(en)
|
2021-03-24 |
2022-09-29 |
Vib Vzw |
Nek6 inhibition to treat als and ftd
|
|
GB202104104D0
(en)
|
2021-03-24 |
2021-05-05 |
Liliumx Ltd |
Platform and method
|
|
US20240376224A1
(en)
|
2021-04-02 |
2024-11-14 |
The Regents Of The University Of California |
Antibodies against cleaved cdcp1 and uses thereof
|
|
WO2022216524A1
(en)
|
2021-04-07 |
2022-10-13 |
Century Therapeutics, Inc. |
Combined artificial cell death/reporter system polypeptide for chimeric antigen receptor cell and uses thereof
|
|
CN117441010A
(zh)
|
2021-04-07 |
2024-01-23 |
世纪治疗股份有限公司 |
从诱导多能干细胞产生α-βT细胞的组合物和方法
|
|
TW202304979A
(zh)
|
2021-04-07 |
2023-02-01 |
瑞士商諾華公司 |
抗TGFβ抗體及其他治療劑用於治療增殖性疾病之用途
|
|
JP2024519515A
(ja)
|
2021-04-07 |
2024-05-15 |
センチュリー セラピューティクス,インコーポレイテッド |
人工多能性幹細胞からガンマ-デルタt細胞を生成するための組成物および方法
|
|
KR20240004462A
(ko)
|
2021-04-08 |
2024-01-11 |
마렝고 테라퓨틱스, 인크. |
Tcr에 결합하는 다기능성 분자 및 이의 용도
|
|
US20240182571A1
(en)
|
2021-04-09 |
2024-06-06 |
Ose Immunotherapeutics |
New scaffold for bifunctional molecules with improved properties
|
|
EP4320229A1
(en)
|
2021-04-09 |
2024-02-14 |
Stichting Radboud Universiteit |
Off the shelf proximity biotinylation enzyme
|
|
WO2022214652A1
(en)
|
2021-04-09 |
2022-10-13 |
Ose Immunotherapeutics |
Scaffold for bifunctioanl molecules comprising pd-1 or cd28 and sirp binding domains
|
|
US20240190993A1
(en)
|
2021-04-14 |
2024-06-13 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
New method to improve the anti-tumoral activity of macrophages
|
|
EP4322938A1
(en)
|
2021-04-14 |
2024-02-21 |
Institut National de la Santé et de la Recherche Médicale (INSERM) |
New method to improve nk cells cytotoxicity
|
|
AU2022257093A1
(en)
|
2021-04-16 |
2023-11-02 |
Celgene Corporation |
T cell therapy in patients who have had prior stem cell transplant
|
|
TW202307007A
(zh)
|
2021-05-04 |
2023-02-16 |
美商再生元醫藥公司 |
多特異性fgf21受體促效劑及其等用途
|
|
WO2022236134A1
(en)
|
2021-05-07 |
2022-11-10 |
Surface Oncology, Inc. |
Anti-il-27 antibodies and uses thereof
|
|
WO2022242892A1
(en)
|
2021-05-17 |
2022-11-24 |
Université de Liège |
Anti-cd38 single-domain antibodies in disease monitoring and treatment
|
|
EP4340879A4
(en)
|
2021-05-20 |
2025-03-26 |
Dianthus Therapeutics OpCo, Inc. |
Antibodies that bind to c1s and uses thereof
|
|
WO2022253910A1
(en)
|
2021-06-02 |
2022-12-08 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
A new method to treat an inflammatory skin disease
|
|
JP2024523436A
(ja)
|
2021-06-16 |
2024-06-28 |
上海▲シン▼湾生物科技有限公司 |
Axlタンパク質を標的とする抗体及びその抗原結合断片、その調製方法と使用
|
|
US12275798B2
(en)
|
2021-06-17 |
2025-04-15 |
Boehringer Ingelheim International Gmbh |
Tri-specific binding molecules
|
|
CA3224912A1
(en)
|
2021-06-22 |
2022-12-29 |
Merck Patent Gmbh |
Vhh-based nkp30 binders
|
|
WO2022269473A1
(en)
|
2021-06-23 |
2022-12-29 |
Janssen Biotech, Inc. |
Materials and methods for hinge regions in functional exogenous receptors
|
|
CN114230665B
(zh)
|
2021-06-23 |
2024-03-22 |
苏州智核生物医药科技有限公司 |
CD8α结合多肽及其用途
|
|
WO2022268993A1
(en)
|
2021-06-23 |
2022-12-29 |
Vib Vzw |
Means and methods for selection of specific binders
|
|
US20240343811A1
(en)
|
2021-06-29 |
2024-10-17 |
Shandong Simcere Biopharmacutical Co., Ltd. |
Cd16 antibody and use thereof
|
|
WO2023288046A1
(en)
|
2021-07-15 |
2023-01-19 |
President And Fellows Of Harvard College |
Compositions and methods relating to cells with adhered particles
|
|
CA3227972A1
(en)
|
2021-07-30 |
2023-02-02 |
Shandong Simcere Biopharmaceutical Co., Ltd. |
Anti-pvrig/anti-tigit bispecific antibodies and applications thereof
|
|
EP4377352A2
(en)
|
2021-07-30 |
2024-06-05 |
Vib Vzw |
Cation-independent mannose-6-phosphate receptor binders for targeted protein degradation
|
|
CN118019548A
(zh)
|
2021-08-06 |
2024-05-10 |
蒙彼利埃癌症研究所 |
用于治疗癌症的方法
|
|
WO2023019171A1
(en)
|
2021-08-10 |
2023-02-16 |
Viridian Therapeutics, Inc. |
Compositions, doses, and methods for treatment of thyroid eye disease
|
|
WO2023023220A1
(en)
|
2021-08-20 |
2023-02-23 |
Alexion Pharmaceuticals, Inc. |
Methods for treating sickle cell disease or beta thalassemia using a complement alternative pathway inhibitor
|
|
WO2023023227A1
(en)
|
2021-08-20 |
2023-02-23 |
Alexion Pharmaceuticals, Inc. |
Methods for treating sickle cell disease or beta thalassemia using complement alternative pathway inhibitors
|
|
JP2024531462A
(ja)
|
2021-08-24 |
2024-08-29 |
江▲蘇▼恒瑞医▲薬▼股▲フン▼有限公司 |
Fap/cd40結合分子及びその医薬的使用
|
|
WO2023041985A2
(en)
|
2021-09-15 |
2023-03-23 |
New York University In Abu Dhabicorporation |
Compositions that block activation of the sars-cov-2 replication and transcription complex (rtc) and methods of use thereof
|
|
TW202328195A
(zh)
|
2021-09-15 |
2023-07-16 |
大陸商江蘇恆瑞醫藥股份有限公司 |
特異性結合pd-1的蛋白及其醫藥用途
|
|
US20240376207A1
(en)
|
2021-09-15 |
2024-11-14 |
Jiangsu Hengrui Pharmaceuticals Co., Ltd. |
Pharmaceutical composition comprising anti-pvrig/tigit bispecific antibody
|
|
US20240316061A1
(en)
|
2021-09-17 |
2024-09-26 |
Institut Curie |
Bet inhibitors for treating pab1 deficient cancer
|
|
EP4405396A2
(en)
|
2021-09-20 |
2024-07-31 |
Voyager Therapeutics, Inc. |
Compositions and methods for the treatment of her2 positive cancer
|
|
US20250134952A1
(en)
|
2021-09-20 |
2025-05-01 |
Institut National de la Santé et de la Recherche Médicale |
Methods for improving the efficacy of hdac inhibitor therapy and predicting the response to treatment with hdac inhibitor
|
|
WO2023057484A1
(en)
|
2021-10-06 |
2023-04-13 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for predicting and improving the efficacy of mcl-1 inhibitor therapy
|
|
WO2023057601A1
(en)
|
2021-10-06 |
2023-04-13 |
Biotalys NV |
Anti-fungal polypeptides
|
|
CA3233824A1
(en)
|
2021-10-08 |
2023-04-13 |
Samir Mitragotri |
Ionic liquids for drug delivery
|
|
CA3234995A1
(en)
|
2021-10-14 |
2023-04-20 |
Latticon (Suzhou) Biopharmaceuticals Co., Ltd. |
Novel antibody-cytokine fusion protein, preparation method therefor and use thereof
|
|
WO2023073099A1
(en)
|
2021-10-28 |
2023-05-04 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Method to improve phagocytosis
|
|
WO2023078906A1
(en)
|
2021-11-03 |
2023-05-11 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Method for treating acute myeloid leukemia
|
|
EP4177266A1
(en)
|
2021-11-05 |
2023-05-10 |
Katholieke Universiteit Leuven |
Neutralizing anti-sars-cov-2 human antibodies
|
|
WO2023079137A1
(en)
|
2021-11-05 |
2023-05-11 |
Katholieke Universiteit Leuven |
Neutralizing anti-sars-cov-2 human antibodies
|
|
JP2024542409A
(ja)
|
2021-11-09 |
2024-11-15 |
オーエスイー・イミュノセラピューティクス |
Clec-1リガンドの同定及びその使用
|
|
JP2024542173A
(ja)
|
2021-11-09 |
2024-11-13 |
アクティム・セラピューティクス・インコーポレイテッド |
マクロファージを処置に適している表現型に変換するための免疫刺激細菌および処置のための対象の同定のためのコンパニオン診断法
|
|
EP4180518A1
(en)
|
2021-11-12 |
2023-05-17 |
Istituto Europeo di Oncologia S.r.l. |
T cells and uses thereof
|
|
US20250034559A1
(en)
|
2021-11-17 |
2025-01-30 |
Voyager Therapeutics, Inc. |
Compositions and methods for the treatment of tau-related disorders
|
|
EP4433089A1
(en)
|
2021-11-19 |
2024-09-25 |
Institut Curie |
Methods for the treatment of hrd cancer and brca-associated cancer
|
|
EP4437547A1
(en)
|
2021-11-22 |
2024-10-02 |
Ablynx N.V. |
Obtaining sequence information for target multivalent immunoglobulin single variable domains
|
|
WO2023089159A1
(en)
|
2021-11-22 |
2023-05-25 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
New strategy targeting stroma/tumor cell crosstalk to treat a cancer
|
|
WO2023097254A1
(en)
|
2021-11-24 |
2023-06-01 |
Visterra, Inc. |
Engineered antibody molecules to cd138 and uses thereof
|
|
JP2024544598A
(ja)
|
2021-11-24 |
2024-12-03 |
ノバルティス アーゲー |
アデノ随伴ウイルス形質導入の調節因子及びその使用
|
|
US20250026842A1
(en)
|
2021-11-29 |
2025-01-23 |
Jiangsu Hengrui Pharmaceuticals Co., Ltd. |
Modified protein or polypeptide
|
|
EP4442273A1
(en)
|
2021-11-30 |
2024-10-09 |
Suzhou Alphamab Co., Ltd. |
Method for preventing and/or treating thromboembolic diseases
|
|
CA3238574A1
(en)
|
2021-12-01 |
2023-06-08 |
Gregory Babcock |
Methods of using interleukin-2 agents
|
|
WO2023099763A1
(en)
|
2021-12-03 |
2023-06-08 |
Institut Curie |
Sirt6 inhibitors for use in treating resistant hrd cancer
|
|
CN118696058A
(zh)
|
2021-12-03 |
2024-09-24 |
山东先声生物制药有限公司 |
抗bcma纳米抗体及其应用
|
|
IL313473A
(en)
|
2021-12-15 |
2024-08-01 |
Interius Biotherapeutics Inc |
Pseudotyped viral particles, compositions comprising the same, and uses thereof
|
|
EP4448574A1
(en)
|
2021-12-17 |
2024-10-23 |
Ablynx N.V. |
Polypeptides comprising immunoglobulin single variable domains targeting tcralphabeta, cd33 and cd123
|
|
JP2025501206A
(ja)
|
2021-12-31 |
2025-01-17 |
山▲東▼先声生物制▲薬▼有限公司 |
Gprc5d抗体及びその応用
|
|
EP4209508A1
(en)
|
2022-01-11 |
2023-07-12 |
Centre national de la recherche scientifique |
Nanobodies for the deneddylating enzyme nedp1
|
|
EP4463479A1
(en)
|
2022-01-12 |
2024-11-20 |
Vib Vzw |
Human ntcp binders for therapeutic use and liver-specific targeted delivery
|
|
WO2023147470A2
(en)
|
2022-01-28 |
2023-08-03 |
Georgiamune Inc. |
Antibodies to programmed cell death protein 1 that are pd-1 agonists
|
|
GB202201137D0
(en)
|
2022-01-28 |
2022-03-16 |
Thelper As |
Therapeutic and diagnostic agents and uses thereof
|
|
WO2023148291A1
(en)
|
2022-02-02 |
2023-08-10 |
Biotalys NV |
Methods for genome editing
|
|
TW202342548A
(zh)
|
2022-02-07 |
2023-11-01 |
美商威特拉公司 |
抗獨特型(anti-idiotype)抗體分子及其用途
|
|
WO2023148397A1
(en)
|
2022-02-07 |
2023-08-10 |
Vib Vzw |
Engineered stabilizing aglycosylated fc-regions
|
|
WO2023151894A1
(en)
|
2022-02-11 |
2023-08-17 |
Henkel Ag & Co. Kgaa |
Process for the synthesis of alpha-methylene-gamma-butyrolactone
|
|
WO2023164487A1
(en)
|
2022-02-22 |
2023-08-31 |
Brown University |
Compositions and methods to achieve systemic uptake of particles following oral or mucosal administration
|
|
EP4496815A1
(en)
|
2022-03-23 |
2025-01-29 |
Bodhi Bio LLC |
Compositions and methods for antigen-specific therapy
|
|
JP2025510997A
(ja)
|
2022-03-30 |
2025-04-15 |
ノバルティス アーゲー |
抗ナトリウム利尿ペプチド受容体1(npr1)抗体を使用して障害を治療する方法
|
|
WO2023201238A1
(en)
|
2022-04-11 |
2023-10-19 |
Vor Biopharma Inc. |
Binding agents and methods of use thereof
|
|
WO2023198806A1
(en)
|
2022-04-13 |
2023-10-19 |
Ose Immunotherapeutics |
New class of molecules for selective clearance of antibody
|
|
EP4508082A1
(en)
|
2022-04-13 |
2025-02-19 |
Vib Vzw |
An ltbr agonist in combination therapy against cancer
|
|
EP4507779A1
(en)
|
2022-04-14 |
2025-02-19 |
Institut National de la Santé et de la Recherche Médicale |
Methods for controlling the tumor cell killing by light
|
|
AU2023262513A1
(en)
|
2022-04-25 |
2024-12-05 |
Visterra, Inc. |
Antibody molecules to april and uses thereof
|
|
EP4514390A1
(en)
|
2022-04-28 |
2025-03-05 |
The United States of America, as represented by the Secretary, Department of Health and Human Services |
Recombinant polypeptides comprising single-domain antibodies targeting herv-k subtype hml-2
|
|
JP2025516262A
(ja)
|
2022-05-02 |
2025-05-27 |
アーカス バイオサイエンシズ インコーポレイティド |
抗tigit抗体及びその使用
|
|
WO2023213751A1
(en)
|
2022-05-02 |
2023-11-09 |
Umc Utrecht Holding B.V |
Single domain antibodies for the detection of plasmin-cleaved vwf
|
|
WO2023216981A1
(zh)
|
2022-05-07 |
2023-11-16 |
北京拓界生物医药科技有限公司 |
松弛素或类似物的融合蛋白及其医药用途
|
|
US20250223326A1
(en)
|
2022-05-10 |
2025-07-10 |
Institut National de la Santé et de la Recherche Médicale |
Syncitin-1 fusion proteins and uses thereof for cargo delivery into target cells
|
|
WO2023220641A2
(en)
|
2022-05-11 |
2023-11-16 |
Juno Therapeutics, Inc. |
Methods and uses related to t cell therapy and production of same
|
|
CN119546628A
(zh)
|
2022-05-11 |
2025-02-28 |
再生元制药公司 |
多特异性结合分子前蛋白及其用途
|
|
EP4522757A2
(en)
|
2022-05-13 |
2025-03-19 |
Voyager Therapeutics, Inc. |
Compositions and methods for the treatment of her2 positive cancer
|
|
CN119213034A
(zh)
|
2022-05-17 |
2024-12-27 |
苏州创胜医药集团有限公司 |
双功能蛋白质及其制剂和用途
|
|
US20250313611A1
(en)
|
2022-05-18 |
2025-10-09 |
Vib Vzw |
Sarbecovirus spike s2 subunit binders
|
|
EP4527853A1
(en)
|
2022-05-19 |
2025-03-26 |
Shaperon Inc. |
Bispecific humanized single domain antibody to pd-l1 and cd47, and use thereof
|
|
WO2023224715A1
(en)
|
2022-05-19 |
2023-11-23 |
Massachusetts Institute Of Technology |
Car cells targeting an inserted ligand
|
|
WO2023230128A1
(en)
|
2022-05-25 |
2023-11-30 |
Surface Oncology, Inc. |
Use of anti-il-27 antibodies
|
|
US20240025987A1
(en)
|
2022-05-25 |
2024-01-25 |
Surface Oncology, Inc. |
Use of anti-il-27 antibodies
|
|
US20250345432A1
(en)
|
2022-05-25 |
2025-11-13 |
Celgene Corporation |
Method for predicting response to a t cell therapy
|
|
CA3250546A1
(en)
|
2022-05-30 |
2023-12-07 |
Ose Immunotherapeutics |
IL7R MODULATOR ACTIVITY BIOMARKERS
|
|
KR20250019077A
(ko)
|
2022-05-31 |
2025-02-07 |
퓨쳐진 바이오파머쓰티컬 (베이징) 코., 엘티디. |
항-cd40 항체 및 항-pd-l1×cd40 이중특이성 항체 및 이의 용도
|
|
JP2025522351A
(ja)
|
2022-06-06 |
2025-07-15 |
山▲東▼先声生物制▲薬▼有限公司 |
Bcma、gprc5d及びt細胞を標的とする多重特異性抗体並びにその応用
|
|
CA3258639A1
(en)
|
2022-06-07 |
2023-12-14 |
Regeneron Pharma |
Multispecific molecules to modulate T lymphocyte activity, and their uses
|
|
WO2023240124A1
(en)
|
2022-06-07 |
2023-12-14 |
Regeneron Pharmaceuticals, Inc. |
Pseudotyped viral particles for targeting tcr-expressing cells
|
|
WO2023240156A1
(en)
|
2022-06-08 |
2023-12-14 |
Tidal Therapeutics, Inc. |
Ionizable cationic lipids and lipid nanoparticles, and methods of synthesis and use thereof
|
|
US20240109965A1
(en)
|
2022-06-14 |
2024-04-04 |
Ablynx N.V. |
Immunoglobulin single variable domains targeting t cell receptor
|
|
WO2024003873A1
(en)
|
2022-06-30 |
2024-01-04 |
Intrexon Actobiotics Nv D/B/A Precigen Actobio |
Single variable domain antibodies against tumor necrosis factor-alpha
|
|
EP4299124A1
(en)
|
2022-06-30 |
2024-01-03 |
Universite De Montpellier |
Anti-mglur2 nanobodies for use as biomolecule transporter
|
|
EP4299125A1
(en)
|
2022-06-30 |
2024-01-03 |
Universite De Montpellier |
Anti-mglur2 biparatopic nanobodies and uses thereof
|
|
JP2025523630A
(ja)
|
2022-07-04 |
2025-07-23 |
ブイアイビー ブイゼットダブリュ |
血液-脳脊髄液関門通過抗体
|
|
PE20251082A1
(es)
|
2022-07-08 |
2025-04-10 |
Novo Nordisk As |
Compuestos de isvd altamente potentes capaces de sustituir al fviii(a)
|
|
AR129879A1
(es)
|
2022-07-08 |
2024-10-09 |
Novo Nordisk As |
Compuestos de isvd altamente potentes capaces de sustituir al fviii(a)
|
|
PE20250669A1
(es)
|
2022-07-15 |
2025-03-04 |
Boehringer Ingelheim Int |
Moleculas de union para el tratamiento del cancer
|
|
KR20250040019A
(ko)
|
2022-07-18 |
2025-03-21 |
아블린쓰 |
Cx3cr1 결합 화합물, 이의 용도, 및 관련 방법
|
|
CA3262611A1
(en)
|
2022-07-22 |
2024-01-25 |
Janssen Biotech Inc |
IMPROVED TRANSFER OF GENETIC INSTRUCTIONS TO EFFECTOR IMMUNE CELLS
|
|
WO2024026284A2
(en)
|
2022-07-25 |
2024-02-01 |
Interius Biotherapeutics, Inc. |
Mutated polypeptides, compositions comprising the same, and uses thereof
|
|
JP2025526384A
(ja)
|
2022-07-27 |
2025-08-13 |
アブリンクス エン.ヴェー. |
新生児型Fc受容体の特異的エピトープに結合するポリペプチド
|
|
CN119855827A
(zh)
|
2022-08-01 |
2025-04-18 |
Ose免疫疗法公司 |
异源二聚Fc-CLEC-1融合分子及其用途
|
|
JP2025525886A
(ja)
|
2022-08-02 |
2025-08-07 |
オーエスイー・イミュノセラピューティクス |
Cd28に対する多機能性分子
|
|
TW202435912A
(zh)
|
2022-08-03 |
2024-09-16 |
美商航海家醫療公司 |
用於穿過血腦屏障之組合物及方法
|
|
WO2024028476A1
(en)
|
2022-08-05 |
2024-02-08 |
Institut National de la Santé et de la Recherche Médicale |
Methods for the treatment of th2-mediated diseases
|
|
WO2024037910A1
(en)
|
2022-08-17 |
2024-02-22 |
Institut National de la Santé et de la Recherche Médicale |
Syk inhibitors for use in the treatment of cancer
|
|
EP4577578A1
(en)
|
2022-08-22 |
2025-07-02 |
Abdera Therapeutics Inc. |
Dll3 binding molecules and uses thereof
|
|
EP4580658A1
(en)
|
2022-08-31 |
2025-07-09 |
Institut National de la Santé et de la Recherche Médicale |
Method to generate more efficient car-t cells
|
|
WO2024049951A1
(en)
|
2022-08-31 |
2024-03-07 |
Alexion Pharmaceuticals, Inc. |
Dosage and administration of fusion polypeptides for treatment of sickle cell disease
|
|
JP2025529210A
(ja)
|
2022-09-01 |
2025-09-04 |
ユニバーシティ・オブ・ジョージア・リサーチ・ファウンデイション・インコーポレイテッド |
アポリポタンパク質l1を導いて哺乳動物の細胞死を誘導するための組成物及び方法
|
|
CA3266977A1
(en)
|
2022-09-06 |
2024-03-14 |
Alexion Pharma Inc |
DIAGNOSTIC AND PROGNOSIS BIOMARKER PROFILES IN PATIENTS WITH HEMATOPOIETIC STEM CELL TRANSPLANT-ASSOCIATED THROMBOTIC MICROANGIOPATHY (HSCT-TMA)
|
|
CA3266599A1
(en)
|
2022-09-07 |
2024-11-07 |
Quantitative Biosciences Inc |
UNIQUE VARIABLE DOMAIN ANTIBODIES SPECIFIC TO FENTANYL AND USE IN A CONTINUOUS AGGLUTINATION TEST
|
|
WO2024055034A1
(en)
|
2022-09-09 |
2024-03-14 |
Yale University |
Proteolysis targeting antibodies and methods of use thereof
|
|
KR20250069606A
(ko)
|
2022-09-15 |
2025-05-19 |
보이저 테라퓨틱스, 인크. |
타우 결합 화합물
|
|
CA3266372A1
(en)
|
2022-09-15 |
2024-03-21 |
Novartis Ag |
TREATMENT OF AUTOIMMUNE DISORDERS USING CHIMERIC ANTIGEN RECEPTOR THERAPY
|
|
WO2024068744A1
(en)
|
2022-09-27 |
2024-04-04 |
Vib Vzw |
Antivirals against human parainfluenza virus
|
|
EP4594344A2
(en)
|
2022-09-28 |
2025-08-06 |
Valink Therapeutics Ltd |
Multivalent proteins and screening methods
|
|
TW202430561A
(zh)
|
2022-09-30 |
2024-08-01 |
法商賽諾菲公司 |
抗cd28抗體
|
|
WO2024074713A1
(en)
|
2022-10-07 |
2024-04-11 |
Institut National de la Santé et de la Recherche Médicale |
Method to generate improving car-t cells
|
|
WO2024083843A1
(en)
|
2022-10-18 |
2024-04-25 |
Confo Therapeutics N.V. |
Amino acid sequences directed against the melanocortin 4 receptor and polypeptides comprising the same for the treatment of mc4r-related diseases and disorders
|
|
WO2024088424A1
(zh)
|
2022-10-28 |
2024-05-02 |
嘉和生物药业有限公司 |
新型抗ctla4抗体
|
|
EP4612180A1
(en)
|
2022-10-31 |
2025-09-10 |
Stichting Amsterdam UMC |
Single domain anti-cd169 antibodies
|
|
EP4613768A1
(en)
|
2022-11-02 |
2025-09-10 |
Suzhou Alphamab Co., Ltd |
Gipr binding protein and use thereof
|
|
WO2024101989A1
(en)
|
2022-11-08 |
2024-05-16 |
Stichting Amsterdam UMC |
Activation inducible antigen receptors for adoptive immunotherapy
|
|
WO2024102962A1
(en)
|
2022-11-10 |
2024-05-16 |
Immuvia Inc |
Cytotoxic bispecific antibodies binding to dr5 and muc16 and uses thereof
|
|
JP2025537809A
(ja)
|
2022-11-15 |
2025-11-20 |
アイメック・ヴェーゼットウェー |
液滴操作のための方法およびシステム
|
|
KR20250152696A
(ko)
|
2022-11-21 |
2025-10-23 |
다이안서스 테라퓨틱스 오피씨오, 인코포레이티드. |
C1s에 결합하는 항체 및 이의 용도
|
|
AU2023404602A1
(en)
|
2022-11-29 |
2025-05-29 |
Jiangsu Hengrui Pharmaceuticals Co., Ltd. |
Cldn18.2/4-1bb binding protein and medical use thereof
|
|
IL319951A
(en)
|
2022-11-30 |
2025-05-01 |
Integral Molecular Inc |
Antibodies targeting claudin 6, including its bispecific formats
|
|
EP4626401A1
(en)
|
2022-12-01 |
2025-10-08 |
Generation Bio Co. |
Stealth lipid nanoparticle compositions for cell targeting
|
|
WO2024123963A2
(en)
|
2022-12-07 |
2024-06-13 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Neutralizing monoclonal antibodies against western, eastern, and venezuelan equine encephalitis virus (eev)
|
|
WO2024126363A1
(en)
|
2022-12-12 |
2024-06-20 |
Institut National de la Santé et de la Recherche Médicale |
Image-based high-content screening methods for identifying compounds targeting apicomplexan parasites
|
|
EP4634214A1
(en)
|
2022-12-15 |
2025-10-22 |
Aarhus Universitet |
Synthetic activation of multimeric transmembrane receptors
|
|
US12195546B2
(en)
|
2022-12-19 |
2025-01-14 |
Sanofi |
CD28/OX40 bispecific antibodies
|
|
CN120380012A
(zh)
|
2022-12-19 |
2025-07-25 |
Umc乌德勒支控股有限公司 |
Btn2a1结合肽
|
|
EP4638502A2
(en)
|
2022-12-21 |
2025-10-29 |
Genzyme Corporation |
Anti-pd-1×4-1bb binding proteins
|
|
WO2024133723A1
(en)
|
2022-12-22 |
2024-06-27 |
Institut National de la Santé et de la Recherche Médicale |
Methods for decreasing therapeutic acquired resistance to chemotherapy and/or radiotherapy
|
|
WO2024133937A1
(en)
|
2022-12-22 |
2024-06-27 |
Biotalys NV |
Methods for genome editing
|
|
TW202440614A
(zh)
|
2022-12-23 |
2024-10-16 |
比利時商艾伯霖克斯公司 |
基於蛋白質的接合載體
|
|
EP4640715A1
(en)
|
2022-12-23 |
2025-10-29 |
Chimagen Biosciences, Ltd |
Multi-specific polypeptide complex targeting gprc5d
|
|
TW202440159A
(zh)
|
2022-12-29 |
2024-10-16 |
大陸商蘇州創勝醫藥集團有限公司 |
含有治療性抗體的藥物製劑及其用途
|
|
WO2024145551A1
(en)
|
2022-12-29 |
2024-07-04 |
Biotalys NV |
Agrochemical compositions
|
|
EP4642233A1
(en)
|
2022-12-30 |
2025-11-05 |
Biotalys NV |
Agglomerate
|
|
WO2024143925A1
(ko)
|
2022-12-30 |
2024-07-04 |
연세대학교 산학협력단 |
Rnase a에 특이적으로 결합하는 항체 또는 펩티드, 및 rnase a 검출 면역분석 장치 및 방법 그리고 rnase a 포집 방법
|
|
WO2024141638A1
(en)
|
2022-12-30 |
2024-07-04 |
Biotalys NV |
Self-emulsifiable concentrate
|
|
WO2024141641A2
(en)
|
2022-12-30 |
2024-07-04 |
Biotalys NV |
Secretion signals
|
|
AU2024207151A1
(en)
|
2023-01-09 |
2025-06-19 |
Odyssey Therapeutics, Inc. |
Anti-tnfr2 antigen-binding proteins and uses thereof
|
|
KR20250133913A
(ko)
|
2023-01-09 |
2025-09-09 |
베이징 투오 지에 바이오파마수티컬 컴퍼니 리미티드 |
TGFβ1 결합 분자, GARP-TGFβ1 결합 분자 및 이의 의학적 용도
|
|
EP4649092A1
(en)
|
2023-01-13 |
2025-11-19 |
Regeneron Pharmaceuticals, Inc. |
Fgfr3 binding molecules and methods of use thereof
|
|
TW202434629A
(zh)
|
2023-01-26 |
2024-09-01 |
愛爾蘭商歐薩爾普羅席納有限公司 |
以抗類澱粉β (ABETA)抗體治療神經病症之方法
|
|
WO2024156888A1
(en)
|
2023-01-27 |
2024-08-02 |
Vib Vzw |
Cd163-binding conjugates
|
|
EP4655323A1
(en)
|
2023-01-27 |
2025-12-03 |
Vrije Universiteit Brussel |
Cd8b-binding polypeptides
|
|
KR20250143339A
(ko)
|
2023-02-06 |
2025-10-01 |
메르크 파텐트 게엠베하 |
VHH-기반 NKp46 결합제
|
|
WO2024168061A2
(en)
|
2023-02-07 |
2024-08-15 |
Ayan Therapeutics Inc. |
Antibody molecules binding to sars-cov-2
|
|
EP4662246A1
(en)
|
2023-02-09 |
2025-12-17 |
Seni-Preps B.V. |
Immunoglobulin single variable domains that inhibit urease and use thereof
|
|
CN121013866A
(zh)
|
2023-02-10 |
2025-11-25 |
阿穆尼克斯制药公司 |
靶向前列腺特异性膜抗原(psma)的组合物及其制备和使用方法
|
|
TW202448926A
(zh)
|
2023-02-17 |
2024-12-16 |
比利時商艾伯霖克斯公司 |
結合新生兒fc受體之多肽
|
|
WO2024175787A1
(en)
|
2023-02-24 |
2024-08-29 |
Vrije Universiteit Brussel |
Anti-inflammatory pannexin 1 channel inhibitors
|
|
WO2024184810A1
(en)
|
2023-03-06 |
2024-09-12 |
Beigene Switzerland Gmbh |
Anti-cldn6 and anti-cd3 multispecific antibodies and methods of use
|
|
AR132064A1
(es)
|
2023-03-06 |
2025-05-21 |
Beigene Switzerland Gmbh |
Anticuerpos anti-cldn6 y métodos de uso
|
|
TW202436345A
(zh)
|
2023-03-06 |
2024-09-16 |
瑞士商百濟神州瑞士有限責任公司 |
抗cd3多特異性抗體及使用方法
|
|
CN120858176A
(zh)
|
2023-03-07 |
2025-10-28 |
居里研究所 |
Brca相关癌症中的ung/udg抑制
|
|
WO2024184479A1
(en)
|
2023-03-08 |
2024-09-12 |
Institut National de la Santé et de la Recherche Médicale |
Methods for the treatment of food allergy
|
|
TW202444757A
(zh)
|
2023-03-14 |
2024-11-16 |
美商奧迪希治療公司 |
抗cd25抗原結合蛋白及其用途
|
|
US20240344078A1
(en)
|
2023-03-14 |
2024-10-17 |
Aarhus Universitet |
Genetically altered nfr5 receptor kinases
|
|
WO2024194673A1
(en)
|
2023-03-21 |
2024-09-26 |
Institut Curie |
Methods for the treatment of dedifferentiated liposarcoma
|
|
WO2024194401A1
(en)
|
2023-03-21 |
2024-09-26 |
Institut Curie |
Vps4b inhibitor for use in methods for the treatment of hrd cancer
|
|
WO2024194402A1
(en)
|
2023-03-21 |
2024-09-26 |
Institut Curie |
Farnesyl transferase inhibitor for use in methods for the treatment of hrd cancer
|
|
AU2024240821A1
(en)
|
2023-03-23 |
2025-11-06 |
Bodhi Bio Llc |
Compositions and methods for antigen-specific therapy
|
|
CN120958023A
(zh)
|
2023-03-24 |
2025-11-14 |
赛诺菲 |
通过阻断il-13和tslp治疗哮喘
|
|
EP4435005A1
(en)
|
2023-03-24 |
2024-09-25 |
Sanofi |
Asthma treatment by blocking il-13 and tslp
|
|
AU2024245676A1
(en)
|
2023-03-30 |
2025-10-09 |
272BIO Limited |
Gnrh-binding polypeptides and uses thereof
|
|
AU2024243709A1
(en)
|
2023-04-03 |
2025-11-06 |
Katholieke Universiteit Leuven |
Blood-brain barrier crossing antibodies
|
|
WO2024213782A1
(en)
|
2023-04-13 |
2024-10-17 |
Institut Curie |
Methods for the treatment of t-cell acute lymphoblastic leukemia
|
|
WO2024224323A1
(en)
|
2023-04-24 |
2024-10-31 |
King Abdullah University Of Science Of Technology |
Compositions, systems and methods for multiplex detection of target biomarkers in a sample
|
|
WO2024226829A2
(en)
|
2023-04-26 |
2024-10-31 |
Yale University |
Enpp3-binding molecules, compositions formed therefrom, and methods of use thereof for the treatment of cancer
|
|
CN121079319A
(zh)
|
2023-05-08 |
2025-12-05 |
赛诺菲 |
免疫球蛋白单可变结构域的糖基化
|
|
WO2024231348A1
(en)
|
2023-05-11 |
2024-11-14 |
Vib Vzw |
Slc4a4/nbce1 inhibitors
|
|
WO2024238565A1
(en)
|
2023-05-15 |
2024-11-21 |
Vor Biopharma Inc. |
Egf-like module containing mucin-like hormone-like 2 (erm2) binding agents and methods of use thereof
|
|
TW202448951A
(zh)
|
2023-05-17 |
2024-12-16 |
美商奧迪希治療公司 |
經修飾之單域抗體
|
|
WO2024240162A1
(en)
|
2023-05-23 |
2024-11-28 |
Shanghai Allygen Biologics Co., Ltd. |
Pd-l1 and trop-2 targeting conjugates comprising effector molecules and uses thereof
|
|
AU2024274792A1
(en)
|
2023-05-23 |
2025-10-23 |
Sana Biotechnology, Inc. |
Tandem fusogens and related lipid particles
|
|
WO2024251826A1
(en)
|
2023-06-05 |
2024-12-12 |
Vib Vzw |
Glyco-engineered antibody-drug-conjugates comprising an oxime linker
|
|
WO2024251783A1
(en)
|
2023-06-05 |
2024-12-12 |
Sanofi |
Predicting thermal stabilities of immunoglobulin single variable domains using machine-learning models
|
|
WO2024251981A1
(en)
|
2023-06-09 |
2024-12-12 |
Umc Utrecht Holding B.V. |
Detecting and/or modulating susceptibility to btn2a1 and/or btn3a1 targeting therapeutics
|
|
WO2024251983A1
(en)
|
2023-06-09 |
2024-12-12 |
Merck Patent Gmbh |
Il-18 mimetics
|
|
WO2024256527A1
(en)
|
2023-06-13 |
2024-12-19 |
Institut National de la Santé et de la Recherche Médicale |
Use of a cxcl 10 inhibitor for the treatment of transplant vasculopathy
|
|
WO2024259305A1
(en)
|
2023-06-14 |
2024-12-19 |
The Broad Institute, Inc. |
Vhh polypeptides that bind to mesothelin, compositions and methods of use thereof
|
|
AR133055A1
(es)
|
2023-06-22 |
2025-08-20 |
Ablynx Nv |
Dominios variables únicos de inmunoglobulina dirigidos a pd-l1
|
|
WO2024261235A1
(en)
|
2023-06-22 |
2024-12-26 |
Ablynx Nv |
Chimeric proteins for modulating cytokine receptor activity
|
|
WO2024261344A1
(en)
|
2023-06-23 |
2024-12-26 |
Vib Vzw |
Novel binders targeting the multi-drug resistant pathogen acinetobacter baumannii
|
|
TW202515917A
(zh)
|
2023-06-29 |
2025-04-16 |
美商奧迪希治療公司 |
抗trailr2抗原結合蛋白及其用途
|
|
EP4483951A1
(en)
|
2023-06-30 |
2025-01-01 |
Université de Liège |
Single-domain antibody for inhibition of neutrophil elastase activity
|
|
AR133188A1
(es)
|
2023-07-05 |
2025-09-03 |
Ablynx Nv |
ANTAGONISTAS DE FcRn MEJORADOS PARA EL TRATAMIENTO DE ENFERMEDADES Y TRASTORNOS RELACIONADOS CON IgG
|
|
WO2025007195A1
(en)
|
2023-07-05 |
2025-01-09 |
CSL Innovation Pty Ltd |
Methods of treating or preventing a complication of sickle cell disease
|
|
TW202509078A
(zh)
|
2023-07-07 |
2025-03-01 |
美商維里迪恩醫療股份有限公司 |
治療慢性甲狀腺眼病之方法
|
|
WO2025024645A1
(en)
|
2023-07-25 |
2025-01-30 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Rapid method for producing antibodies
|
|
WO2025034806A1
(en)
|
2023-08-08 |
2025-02-13 |
Wisconsin Alumni Research Foundation |
Single-domain antibodies and variants thereof against fibroblast activation protein
|
|
WO2025032158A1
(en)
|
2023-08-08 |
2025-02-13 |
Institut National de la Santé et de la Recherche Médicale |
Method to treat tauopathies
|
|
WO2025032112A1
(en)
|
2023-08-08 |
2025-02-13 |
Institut National de la Santé et de la Recherche Médicale |
Methods for the treatment of type 2-mediated diseases
|
|
WO2025032213A1
(en)
|
2023-08-10 |
2025-02-13 |
Ose Immunotherapeutics |
Identification of hla-dra as a ligand of clec-1 and uses thereof
|
|
WO2025036848A1
(en)
|
2023-08-11 |
2025-02-20 |
Wuxi Biologics (Shanghai) Co., Ltd. |
Anti-muc16 antibodies and uses thereof
|
|
EP4512243A1
(en)
|
2023-08-21 |
2025-02-26 |
Kymab Limited |
Binding molecules
|
|
WO2025051767A1
(en)
|
2023-09-04 |
2025-03-13 |
Sanofi |
Polypeptides for use in the treatment of glypican-3-expressing tumours
|
|
TW202530246A
(zh)
|
2023-09-15 |
2025-08-01 |
愛爾蘭商歐賽爾普羅希那有限公司 |
細胞穿透劑及其用途
|
|
GB202314424D0
(en)
|
2023-09-20 |
2023-11-01 |
Cambridge Entpr Ltd |
A conjugate
|
|
AR133903A1
(es)
|
2023-09-22 |
2025-11-12 |
Ablynx Nv |
Agentes de unión de albúmina bi- y multivalentes
|
|
WO2025068393A1
(en)
|
2023-09-27 |
2025-04-03 |
Institut Curie |
Methods for the treatment of fibrotic related diseases
|
|
WO2025073765A1
(en)
|
2023-10-03 |
2025-04-10 |
Institut National de la Santé et de la Recherche Médicale |
Methods of prognosis and treatment of patients suffering from melanoma
|
|
WO2025073890A1
(en)
|
2023-10-06 |
2025-04-10 |
Institut National de la Santé et de la Recherche Médicale |
Method to capture circulating tumor extracellular vesicles
|
|
WO2025078418A1
(en)
|
2023-10-10 |
2025-04-17 |
Nano Tag Biotechnologies Gmbh |
Humanized single-domain antibodies binding to epitope tags
|
|
WO2025078851A1
(en)
|
2023-10-11 |
2025-04-17 |
Institut National De La Sante Et De La Recherche Medicale (Inserm) |
Methods of treating cognitive deficit
|
|
TW202535921A
(zh)
|
2023-10-11 |
2025-09-16 |
德商拜恩迪克公司 |
用於靶向遞送免疫效應子細胞之試劑及方法
|
|
TW202515903A
(zh)
|
2023-10-12 |
2025-04-16 |
瑞士商百濟神州瑞士有限責任公司 |
手術前後基於抗pd-1之治療
|
|
NL2036011B1
(en)
|
2023-10-12 |
2025-04-30 |
Synapse Res Institute |
Molecules for reversing anti-coagulant activity of direct oral anticoagulants
|
|
TW202530265A
(zh)
|
2023-10-13 |
2025-08-01 |
美商奧迪希治療公司 |
抗cdh17抗原結合蛋白及其用途
|
|
WO2025093541A1
(en)
|
2023-10-31 |
2025-05-08 |
Ose Immunotherapeutics |
Combination of interleukin 7 and tumour associated antigen vaccine
|
|
WO2025093683A1
(en)
|
2023-11-03 |
2025-05-08 |
Neuvasq Biotechnologies Sa |
Wnt7 signaling agonists
|
|
WO2025099632A1
(en)
|
2023-11-08 |
2025-05-15 |
Sanofi |
Cd25 based lysosomal degrader and uses thereof
|
|
WO2025109176A1
(en)
|
2023-11-22 |
2025-05-30 |
Exevir Bio Bv |
Optimized sarbecovirus spike s2 subunit binders and compositions comprising the same
|
|
WO2025114529A1
(en)
|
2023-12-01 |
2025-06-05 |
Ablynx Nv |
Multispecific antibodies recognising human serum albumin, tcr and a tumor antigen recognising moiety
|
|
WO2025122634A1
(en)
|
2023-12-05 |
2025-06-12 |
Voyager Therapeutics, Inc. |
Compositions and methods for the treatment of tau-related disorders
|
|
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(en)
|
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2025-06-19 |
Vib Vzw |
Antibodies against influenza b virus
|
|
TW202535948A
(zh)
|
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用於治療甲狀腺眼病之組合物、劑量及方法
|
|
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(en)
|
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Anti trypsin-3 single domain antibody
|
|
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(en)
|
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Protein-based carriers for site-specific amine conjugation
|
|
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(en)
|
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Immunoglobulin single variable domains targeting ceacam5
|
|
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(en)
|
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Protein-based conjugation carriers for intranuclear delivery
|
|
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(en)
|
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|
|
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(en)
|
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Compositions and methods for treatment of thyroid eye disease
|
|
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(en)
|
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Compositions and methods for treatment of thyroid eye disease
|
|
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(en)
|
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Modified antibodies
|
|
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(en)
|
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|
|
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(en)
|
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|
|
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(en)
|
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Dendrimer conjugate compositions for intracellular delivery of antibodies and antibody fragments
|
|
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(en)
|
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|
|
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(en)
|
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|
|
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(en)
|
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Delivery compositions
|
|
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(en)
|
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Dut inhibition in homologous recombination deficiency cancer
|
|
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(en)
|
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|
|
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(en)
|
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|
|
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(en)
|
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|
|
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(en)
|
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|
|
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(en)
|
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|
|
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(en)
|
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Means and methods for displaying fc-containing proteins on cells and selection thereof
|
|
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(en)
|
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|
|
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(en)
|
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Compass Therapeutics, Inc. |
Combination of antibodies targeting dll4/vegf and cd137 agonists or anti-pd1/anti-pd-l1 antibodies for the treatment of cancer
|
|
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(en)
|
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Anti-tnfr2 antigen-binding proteins and uses thereof
|
|
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(en)
|
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Computer-implemented means and methods for the de novo design of antibodies targeting a specific epitope
|
|
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(en)
|
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|
|
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(en)
|
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Methods for treating cancer using anti-ccr8 antibodies
|
|
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(en)
|
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|
|
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(en)
|
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|
|
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(en)
|
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|
|
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(en)
|
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|
|
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(en)
|
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|
|
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(en)
|
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|
|
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(en)
|
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|