DK1581251T3 - Krystaller af humant væksthormon og fremgangsmåder til fremstilling deraf - Google Patents
Krystaller af humant væksthormon og fremgangsmåder til fremstilling derafInfo
- Publication number
- DK1581251T3 DK1581251T3 DK03808602.1T DK03808602T DK1581251T3 DK 1581251 T3 DK1581251 T3 DK 1581251T3 DK 03808602 T DK03808602 T DK 03808602T DK 1581251 T3 DK1581251 T3 DK 1581251T3
- Authority
- DK
- Denmark
- Prior art keywords
- crystals
- producing
- methods
- human growth
- growth hormon
- Prior art date
Links
- 239000013078 crystal Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/27—Growth hormone [GH], i.e. somatotropin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/61—Growth hormone [GH], i.e. somatotropin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2299/00—Coordinates from 3D structures of peptides, e.g. proteins or enzymes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Endocrinology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Toxicology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Virology (AREA)
- Reproductive Health (AREA)
- Physical Education & Sports Medicine (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pregnancy & Childbirth (AREA)
- Diabetes (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Oncology (AREA)
- Gynecology & Obstetrics (AREA)
- Communicable Diseases (AREA)
- AIDS & HIV (AREA)
- Urology & Nephrology (AREA)
- Dermatology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US43751902P | 2002-12-31 | 2002-12-31 | |
| US51704203P | 2003-11-03 | 2003-11-03 | |
| PCT/US2003/041545 WO2004060310A2 (en) | 2002-12-31 | 2003-12-31 | Human growth hormone crystals and methods for preparing them |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1581251T3 true DK1581251T3 (da) | 2016-06-27 |
Family
ID=32717908
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK03808602.1T DK1581251T3 (da) | 2002-12-31 | 2003-12-31 | Krystaller af humant væksthormon og fremgangsmåder til fremstilling deraf |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US9376479B2 (da) |
| EP (2) | EP1581251B1 (da) |
| JP (2) | JP4686361B2 (da) |
| KR (1) | KR20050090430A (da) |
| AU (2) | AU2003303646B2 (da) |
| BR (1) | BR0317888A (da) |
| CA (1) | CA2512052C (da) |
| DK (1) | DK1581251T3 (da) |
| MX (1) | MXPA05007181A (da) |
| RU (1) | RU2357750C2 (da) |
| SG (1) | SG176314A1 (da) |
| WO (1) | WO2004060310A2 (da) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1581251T3 (da) | 2002-12-31 | 2016-06-27 | Althea Tech Inc | Krystaller af humant væksthormon og fremgangsmåder til fremstilling deraf |
| WO2004060920A1 (en) * | 2002-12-31 | 2004-07-22 | Altus Pharmaceuticals Inc. | Complexes of protein crystals and ionic polymers |
| US20090029911A1 (en) * | 2003-09-25 | 2009-01-29 | Ashley Martin Williams | Liquid Human Growth Hormone Formulation Containing Polyethylene Glycol |
| US8728525B2 (en) | 2004-05-12 | 2014-05-20 | Baxter International Inc. | Protein microspheres retaining pharmacokinetic and pharmacodynamic properties |
| EP1888117A1 (en) * | 2005-05-25 | 2008-02-20 | Novo Nordisk A/S | Stabilized polypeptide formulations |
| WO2006125763A1 (en) | 2005-05-25 | 2006-11-30 | Novo Nordisk A/S | Stabilized polypeptide formulations |
| CA2634053A1 (en) * | 2005-12-23 | 2007-07-05 | Altus Pharmaceuticals Inc. | Compositions comprising polycation-complexed protein crystals and methods of treatment using them |
| US10351615B2 (en) | 2006-02-03 | 2019-07-16 | Opko Biologics Ltd. | Methods of treatment with long-acting growth hormone |
| US9249407B2 (en) | 2006-02-03 | 2016-02-02 | Opko Biologics Ltd. | Long-acting coagulation factors and methods of producing same |
| EP2647712A3 (en) | 2006-08-04 | 2013-11-20 | Baxter International Inc | Microsphere-based composition for preventing and/or reversing new-onset autoimmune diabetes |
| MX2009002314A (es) * | 2006-08-31 | 2009-03-20 | Novartis Ag | Composiciones farmaceuticas que comprenden hgh para suministro oral. |
| EP2486916B1 (en) | 2006-12-18 | 2015-04-01 | Ajinomoto Althea, Inc. | Human growth hormone formulations |
| US8367412B2 (en) | 2007-02-23 | 2013-02-05 | Kwansei Gakuin Educational Foundation | Protein crystallizing agent and method of crystallizing protein therewith |
| US20110091992A1 (en) * | 2007-07-10 | 2011-04-21 | Medimmune, Llc | CRYSTALS AND STRUCTURE OF HUMAN IgG Fc VARIANT |
| EP2111871A1 (de) * | 2008-04-26 | 2009-10-28 | Sandoz AG | Stabilisierte Flüssigformulierung |
| US8367427B2 (en) | 2008-08-20 | 2013-02-05 | Baxter International Inc. | Methods of processing compositions containing microparticles |
| US8323615B2 (en) | 2008-08-20 | 2012-12-04 | Baxter International Inc. | Methods of processing multi-phasic dispersions |
| US8323685B2 (en) * | 2008-08-20 | 2012-12-04 | Baxter International Inc. | Methods of processing compositions containing microparticles |
| CA2753641C (en) * | 2009-02-25 | 2014-09-16 | Supratek Pharma, Inc. | Bendamustine cyclopolysaccharide compositions |
| US9663778B2 (en) | 2009-07-09 | 2017-05-30 | OPKO Biologies Ltd. | Long-acting coagulation factors and methods of producing same |
| US12203113B2 (en) | 2009-07-09 | 2025-01-21 | Opko Biologics Ltd. | Long-acting coagulation factors and methods of producing same |
| MX362286B (es) | 2011-11-18 | 2019-01-10 | Regeneron Pharma | Microparticulas de polimero y proteina. |
| US20150158926A1 (en) | 2013-10-21 | 2015-06-11 | Opko Biologics, Ltd. | Long-acting polypeptides and methods of producing and administering same |
| EP3064213A4 (en) * | 2013-10-28 | 2017-04-26 | Terumo Kabushiki Kaisha | Protein aqueous suspension |
| SI3230309T1 (sl) | 2014-12-10 | 2023-08-31 | Opko Biologics Ltd. | Postopki za proizvodnjo dolgo delujočih, s CTP-spremenjenih polipeptidov rastnega hormona |
| US10960058B2 (en) | 2015-06-19 | 2021-03-30 | Opko Biologics Ltd. | Long-acting coagulation factors and methods of producing same |
| EA036623B1 (ru) * | 2015-10-16 | 2020-12-01 | Ридженерон Фармасьютикалз, Инк. | Стабильные белковые композиции |
| IL264208B2 (en) | 2016-07-11 | 2025-02-01 | Opko Biologics Ltd | Long-acting clotting factors and methods for their preparation |
| JP7104929B2 (ja) * | 2017-07-24 | 2022-07-22 | テルモ株式会社 | 医療用タンパク質とポリアミノ酸とを含む複合体の製造方法および医療用タンパク質とポリアミノ酸とを含む複合体 |
| US11541105B2 (en) | 2018-06-01 | 2023-01-03 | The Research Foundation For The State University Of New York | Compositions and methods for disrupting biofilm formation and maintenance |
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| GB643268A (en) | 1944-04-04 | 1950-09-15 | Nordisk Insulinlab | Improved process for the preparation of prolonged effect insulin products |
| US2538018A (en) * | 1944-04-04 | 1951-01-16 | Nordisk Insulinlab | Crystalline product of insulin and alkaline protein and process of making it |
| US4342832A (en) * | 1979-07-05 | 1982-08-03 | Genentech, Inc. | Method of constructing a replicable cloning vehicle having quasi-synthetic genes |
| US5618697A (en) | 1982-12-10 | 1997-04-08 | Novo Nordisk A/S | Process for preparing a desired protein |
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| US4816568A (en) * | 1986-05-16 | 1989-03-28 | International Minerals & Chemical Corp. | Stabilization of growth hormones |
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| WO2004060920A1 (en) * | 2002-12-31 | 2004-07-22 | Altus Pharmaceuticals Inc. | Complexes of protein crystals and ionic polymers |
| DK1581251T3 (da) | 2002-12-31 | 2016-06-27 | Althea Tech Inc | Krystaller af humant væksthormon og fremgangsmåder til fremstilling deraf |
-
2003
- 2003-12-31 DK DK03808602.1T patent/DK1581251T3/da active
- 2003-12-31 WO PCT/US2003/041545 patent/WO2004060310A2/en not_active Ceased
- 2003-12-31 CA CA2512052A patent/CA2512052C/en not_active Expired - Fee Related
- 2003-12-31 KR KR1020057012348A patent/KR20050090430A/ko not_active Ceased
- 2003-12-31 BR BR0317888-9A patent/BR0317888A/pt not_active IP Right Cessation
- 2003-12-31 EP EP03808602.1A patent/EP1581251B1/en not_active Expired - Lifetime
- 2003-12-31 RU RU2005124280/15A patent/RU2357750C2/ru not_active IP Right Cessation
- 2003-12-31 JP JP2005508635A patent/JP4686361B2/ja not_active Expired - Fee Related
- 2003-12-31 EP EP11168985A patent/EP2460530A3/en not_active Withdrawn
- 2003-12-31 AU AU2003303646A patent/AU2003303646B2/en not_active Ceased
- 2003-12-31 US US10/749,962 patent/US9376479B2/en not_active Expired - Lifetime
- 2003-12-31 MX MXPA05007181A patent/MXPA05007181A/es unknown
- 2003-12-31 SG SG2007165756A patent/SG176314A1/en unknown
-
2010
- 2010-04-05 JP JP2010087407A patent/JP2010209079A/ja active Pending
- 2010-05-17 AU AU2010201961A patent/AU2010201961A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CA2512052C (en) | 2016-06-21 |
| MXPA05007181A (es) | 2006-04-07 |
| US20040209804A1 (en) | 2004-10-21 |
| CA2512052A1 (en) | 2004-07-22 |
| KR20050090430A (ko) | 2005-09-13 |
| RU2357750C2 (ru) | 2009-06-10 |
| WO2004060310A8 (en) | 2005-06-02 |
| JP2006512416A (ja) | 2006-04-13 |
| JP2010209079A (ja) | 2010-09-24 |
| EP1581251A2 (en) | 2005-10-05 |
| US9376479B2 (en) | 2016-06-28 |
| WO2004060310A3 (en) | 2004-12-09 |
| JP4686361B2 (ja) | 2011-05-25 |
| AU2003303646B2 (en) | 2010-03-04 |
| WO2004060310A2 (en) | 2004-07-22 |
| EP1581251B1 (en) | 2016-03-16 |
| EP1581251A4 (en) | 2009-03-04 |
| RU2005124280A (ru) | 2006-01-20 |
| AU2003303646A1 (en) | 2004-07-29 |
| AU2010201961A1 (en) | 2010-06-03 |
| SG176314A1 (en) | 2011-12-29 |
| EP2460530A3 (en) | 2012-08-29 |
| EP2460530A2 (en) | 2012-06-06 |
| BR0317888A (pt) | 2005-12-06 |
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