DK1436381T3 - Dedifferentierede, programmerbare stamceller af monocytisk oprindelse og deres fremstilling og anvendelse - Google Patents
Dedifferentierede, programmerbare stamceller af monocytisk oprindelse og deres fremstilling og anvendelseInfo
- Publication number
- DK1436381T3 DK1436381T3 DK03727271T DK03727271T DK1436381T3 DK 1436381 T3 DK1436381 T3 DK 1436381T3 DK 03727271 T DK03727271 T DK 03727271T DK 03727271 T DK03727271 T DK 03727271T DK 1436381 T3 DK1436381 T3 DK 1436381T3
- Authority
- DK
- Denmark
- Prior art keywords
- stem cells
- production
- dedifferentiated
- programmable
- monocytic stem
- Prior art date
Links
- 210000000130 stem cell Anatomy 0.000 title abstract 4
- 238000004519 manufacturing process Methods 0.000 title abstract 3
- 210000001616 monocyte Anatomy 0.000 abstract 2
- 108010002386 Interleukin-3 Proteins 0.000 abstract 1
- 108010046938 Macrophage Colony-Stimulating Factor Proteins 0.000 abstract 1
- 102000007651 Macrophage Colony-Stimulating Factor Human genes 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 239000001963 growth medium Substances 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10214095A DE10214095C1 (de) | 2002-03-28 | 2002-03-28 | Dedifferenzierte, programmierbare Stammzellen monozytären Ursprungs, sowie deren Herstellung und Verwendung |
| US10/372,657 US20040101962A1 (en) | 2002-03-28 | 2003-02-25 | Dedifferentiated, programmable stem cells of monocytic origin, and their production and use |
| PCT/EP2003/003279 WO2003083092A1 (en) | 2002-03-28 | 2003-03-28 | Dedifferentiated, programmable stem cells of monocytic origin, and their production and use |
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| DK1436381T3 true DK1436381T3 (da) | 2005-09-19 |
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| EP (2) | EP1436381B1 (da) |
| JP (2) | JP4146802B2 (da) |
| CN (1) | CN100347293C (da) |
| AT (1) | ATE295876T1 (da) |
| AU (1) | AU2003233950B2 (da) |
| BR (1) | BR0308919A (da) |
| CA (1) | CA2479110C (da) |
| DK (1) | DK1436381T3 (da) |
| ES (1) | ES2242941T3 (da) |
| IL (1) | IL163970A0 (da) |
| NO (1) | NO337668B1 (da) |
| PT (1) | PT1436381E (da) |
| TW (1) | TWI288779B (da) |
| WO (1) | WO2003083092A1 (da) |
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| GB9502022D0 (en) * | 1995-02-02 | 1995-03-22 | Abuljadayel Ilham M S | A method for preparing lymphohaematopoietic progenitor cells |
| TWI288779B (en) * | 2002-03-28 | 2007-10-21 | Blasticon Biotech Forschung | Dedifferentiated, programmable stem cells of monocytic origin, and their production and use |
| DE10231655A1 (de) * | 2002-07-12 | 2004-02-26 | Blasticon Biotechnologische Forschung Gmbh | Transplantat-Akzeptanz induzierende Zellen monozytären Ursprungs, sowie deren Herstellung und Verwendung |
| EP1644484B1 (en) * | 2003-07-11 | 2008-09-17 | Blasticon Biotechnologische Forschung GmbH | Autologous self-tolerance inducing cells of monocytic origin and their use in pharmaceutical proparations |
| EP1581637A4 (en) * | 2002-11-07 | 2007-04-25 | Univ Chicago | MATERIALS AND METHODS WITH HUMAN STEM CELLS |
| US20040136973A1 (en) * | 2002-11-07 | 2004-07-15 | Eliezer Huberman | Human stem cell materials and methods |
| ITRM20030376A1 (it) | 2003-07-31 | 2005-02-01 | Univ Roma | Procedimento per l'isolamento e l'espansione di cellule staminali cardiache da biopsia. |
| WO2005071065A1 (en) * | 2004-01-26 | 2005-08-04 | Cognis France S.A.S | Method for studying functional interactions between sensory neurons and keratinocytes or melanocytes |
| EP1600500A1 (en) * | 2004-05-27 | 2005-11-30 | Georg-August-Universität Göttingen | Method for producing pluripotent cells from monocytes |
| US11660317B2 (en) | 2004-11-08 | 2023-05-30 | The Johns Hopkins University | Compositions comprising cardiosphere-derived cells for use in cell therapy |
| AU2005304708B2 (en) * | 2004-11-08 | 2012-01-19 | The Johns Hopkins University | Cardiac stem cells |
| WO2006096931A1 (en) * | 2005-03-18 | 2006-09-21 | The University Of Queensland | Renal repair and regeneration |
| US9388382B2 (en) | 2005-10-05 | 2016-07-12 | The Board Of Trustees Of The University Of Illinois | Isolation of CD14 negative, CD45 positive and CD117 positive embryonic-like stem cells free of monocytes from human umbilical cord blood mononuclear cells |
| ITTO20050819A1 (it) | 2005-11-18 | 2007-05-19 | Univ Degli Studi Torino | Linea cellulare staminale pluripotente, linee cellulari derivate, procedimenti per la loro produzione e relativi usi |
| CA2651326A1 (en) * | 2006-05-05 | 2007-11-15 | Opexa Therapeutics | Pancreatic islet-like cells |
| CA2651331A1 (en) * | 2006-05-05 | 2007-11-15 | Opexa Therapeutics | Monocyte-derived stem cells |
| WO2007146106A2 (en) * | 2006-06-05 | 2007-12-21 | Cryo- Cell International, Inc. | Procurement, isolation and cryopreservation of maternal placental cells |
| US20080050814A1 (en) * | 2006-06-05 | 2008-02-28 | Cryo-Cell International, Inc. | Procurement, isolation and cryopreservation of fetal placental cells |
| ITRM20060498A1 (it) * | 2006-09-20 | 2008-03-21 | Alessandra Gambacurta | Metodo di espansione di cellule staminali adulte da sangue periferico e relativi usi in campo medico |
| CA2666789C (en) | 2006-10-18 | 2016-11-22 | Yong Zhao | Embryonic-like stem cells derived from adult human peripheral blood and methods of use |
| WO2008058273A2 (en) * | 2006-11-09 | 2008-05-15 | The Johns Hopkins University | Dedifferentiation of adult mammalian cardiomyocytes into cardiac stem cells |
| ITTO20060937A1 (it) * | 2006-12-29 | 2008-06-30 | Medestea Biotech S R L | Linee cellulari immortali differenziate atte a produrre albumina e fattori di crescita, procedimenti per la loro preparazione da una linea cellulare leucemica e loro usi. |
| ES2352046T3 (es) * | 2007-09-21 | 2011-02-15 | Universität Leipzig | Medio de cultivo celular y procedimiento de cultivo de células madre y células progenitor. |
| ITUD20080058A1 (it) | 2008-03-18 | 2009-09-19 | Thankstem S R L | Kit per la raccolta di sangue, preferibilmente periferico, per la produzione di cellule staminali |
| WO2009157610A1 (en) * | 2008-06-26 | 2009-12-30 | Pusan National University Industry-University Cooperation Foundation | Selenium dedifferentiated cell, preparation method and usage thereof |
| US9169463B2 (en) | 2008-11-25 | 2015-10-27 | Otsuka Pharmaceutical Co., Ltd. | Stem cell for therapeutic use which is derived from human monocyte, and method for inducing same |
| KR100950195B1 (ko) * | 2009-03-20 | 2010-03-29 | 서울대학교산학협력단 | Znf281을 발현하는 제대혈 유래 만능 줄기세포의 분리방법 |
| PH12012500714A1 (en) * | 2009-10-19 | 2012-10-29 | Tristem Trading Cyprus Ltd | Treatment using reprogrammed mature adult cells |
| US20110091433A1 (en) * | 2009-10-19 | 2011-04-21 | Ilham Mohamed Saleh Saeed Abuljadayel | Treatment using reprogrammed mature adult cells |
| CN101760446B (zh) * | 2009-12-31 | 2012-09-12 | 浙江中赢控股集团有限公司 | 制备单核细胞型干细胞的方法及应用 |
| US9249392B2 (en) | 2010-04-30 | 2016-02-02 | Cedars-Sinai Medical Center | Methods and compositions for maintaining genomic stability in cultured stem cells |
| US9845457B2 (en) | 2010-04-30 | 2017-12-19 | Cedars-Sinai Medical Center | Maintenance of genomic stability in cultured stem cells |
| JP6000950B2 (ja) * | 2010-08-12 | 2016-10-05 | アーベーアーゲー フェアヴァルトゥングス ゲーエムベーハーAbag Verwaltungs Gmbh | 肝細胞の特徴を有する細胞を産生するための方法並びに同方法により産生された細胞及びその使用 |
| US9809798B2 (en) | 2011-03-11 | 2017-11-07 | National University Of Singapore | Pericyte progenitors from peripheral blood |
| CN109536446B (zh) * | 2012-02-10 | 2022-08-02 | 医疗法人社团博心厚生会 | 单核细胞增殖剂、单核细胞增殖用培养基、及单核细胞的制造方法 |
| US20150072416A1 (en) * | 2012-05-29 | 2015-03-12 | Korea Research Institute Of Bioscience And Biotech | Metabolite for improving production, maintenance and proliferation of pluripotent stem cells, composition comprising the same, and method of culturing pluripotent stem cell using the same |
| EP2861238A4 (en) | 2012-06-05 | 2016-03-16 | Capricor Inc | OPTIMIZED METHODS FOR GENERATING CARDIAC STEM CELLS FROM CARDIAC TISSUE AND THEIR USE IN CARDIAC THERAPY |
| US9828603B2 (en) | 2012-08-13 | 2017-11-28 | Cedars Sinai Medical Center | Exosomes and micro-ribonucleic acids for tissue regeneration |
| JP2016505249A (ja) * | 2012-12-06 | 2016-02-25 | フワン・ピーティーワイ・リミテッド | 多分化能細胞を作製する方法 |
| EP2862926B1 (en) | 2013-10-17 | 2018-12-05 | Centre National de la Recherche Scientifique (CNRS) | Method for in vitro differentiation of blood circulating cells into neuronal-like cells and applications thereof |
| AU2014360678A1 (en) * | 2013-12-06 | 2016-06-23 | Fuwan Pty Ltd | A method of treating neoplasia |
| EA035104B1 (ru) | 2014-05-09 | 2020-04-28 | Танкстем С.Р.Л. | Способ размножения взрослых стволовых клеток из цельной крови |
| US11357799B2 (en) | 2014-10-03 | 2022-06-14 | Cedars-Sinai Medical Center | Cardiosphere-derived cells and exosomes secreted by such cells in the treatment of muscular dystrophy |
| MX2017008738A (es) | 2014-12-31 | 2017-11-17 | Poet Res Inc | Uso de flujo de azucar en fermentacion de etanol para producir otros productos. |
| CA2996582A1 (en) * | 2015-08-31 | 2017-03-09 | I Peace, Inc. | Pluripotent stem cell manufacturing system and method for producing induced pluripotent stem cells |
| EP3402543B1 (en) | 2016-01-11 | 2021-09-08 | Cedars-Sinai Medical Center | Cardiosphere-derived cells and exosomes secreted by such cells in the treatment of heart failure with preserved ejection fraction |
| US11351200B2 (en) | 2016-06-03 | 2022-06-07 | Cedars-Sinai Medical Center | CDC-derived exosomes for treatment of ventricular tachyarrythmias |
| EP3515459A4 (en) | 2016-09-20 | 2020-08-05 | Cedars-Sinai Medical Center | CELLS DERIVED FROM CARDIOSPHERES AND THEIR EXTRACELLULAR VESICLES TO DELAY OR REVERSE AGING AND AGE-RELATED DISORDERS |
| US11759482B2 (en) | 2017-04-19 | 2023-09-19 | Cedars-Sinai Medical Center | Methods and compositions for treating skeletal muscular dystrophy |
| CN107904202B (zh) * | 2017-11-22 | 2018-11-20 | 北京恩诺生物科技有限公司 | 一种制备多能干细胞样细胞的方法、组合物和应用 |
| CN111601606A (zh) | 2017-11-29 | 2020-08-28 | 菲格内有限责任公司 | 用于活化的成纤维细胞与免疫细胞的相互作用及其用途 |
| US11660355B2 (en) | 2017-12-20 | 2023-05-30 | Cedars-Sinai Medical Center | Engineered extracellular vesicles for enhanced tissue delivery |
| EP3749344A4 (en) | 2018-02-05 | 2022-01-26 | Cedars-Sinai Medical Center | METHODS OF THERAPEUTIC USE OF EXOSOMES AND Y-RNAS |
| BR112022018092A2 (pt) | 2020-03-11 | 2022-11-22 | Bit Bio Ltd | Método de gerar células hepáticas |
| JP6826744B1 (ja) * | 2020-07-17 | 2021-02-10 | 医療法人Yanaga CLinic | 成熟脂肪細胞含有組成物の製造方法 |
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| US4281061A (en) * | 1979-07-27 | 1981-07-28 | Syva Company | Double antibody for enhanced sensitivity in immunoassay |
| US4761421A (en) * | 1985-05-08 | 1988-08-02 | Merck & Co., Inc. | Use of certain compounds in livestock food as growth promotants for better feed utilization and improved carcass composition |
| US4783220A (en) * | 1986-12-18 | 1988-11-08 | Xerox Corporation | Vesicle ink compositions |
| US5605835A (en) * | 1988-05-23 | 1997-02-25 | Regents Of The University Of Minnesota | Bioreactor device with application as a bioartificial liver |
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| US5871986A (en) * | 1994-09-23 | 1999-02-16 | The General Hospital Corporation | Use of a baculovirus to express and exogenous gene in a mammalian cell |
| WO1996009074A1 (en) * | 1994-09-23 | 1996-03-28 | The General Hospital Corporation | Use of a non-mammalian dna virus to express an exogenous gene in a mammalian cell |
| GB9502022D0 (en) | 1995-02-02 | 1995-03-22 | Abuljadayel Ilham M S | A method for preparing lymphohaematopoietic progenitor cells |
| US7410773B2 (en) * | 1995-02-02 | 2008-08-12 | Ghazi Jaswinder Dhoot | Method of preparing an undifferentiated cell |
| US7112440B2 (en) * | 1995-02-02 | 2006-09-26 | Ghazi Jaswinder Dhoot | Method of increasing the relative number of CD45 low cells in a cell population |
| US9068164B1 (en) * | 1995-02-02 | 2015-06-30 | Tristem Trading (Cyprus) Limited | Method of preparing an undifferentiated cell |
| US5650309A (en) * | 1995-05-16 | 1997-07-22 | The Regents Of The University Of California | Viral vectors |
| US6043092A (en) * | 1996-03-18 | 2000-03-28 | University Of Pittsburgh | Cell culture media for mammalian cells |
| US5827740A (en) * | 1996-07-30 | 1998-10-27 | Osiris Therapeutics, Inc. | Adipogenic differentiation of human mesenchymal stem cells |
| US6008004A (en) * | 1996-10-04 | 1999-12-28 | Becton Dickinson & Company | Identification of a CD34+ bone marrow precursor for dendritic cells in blood and lymphoid tissues |
| WO1998053048A1 (en) * | 1997-05-21 | 1998-11-26 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Methods and compositions for making dendritic cells from expanded populations of monocytes and for activating t cells |
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| EP1179049A2 (en) | 1999-05-14 | 2002-02-13 | City of Hope | (ex vivo) expansion of mammalian hematopoietic stem cells |
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| US7617122B2 (en) * | 2002-08-28 | 2009-11-10 | International Business Machines Corporation | Targeted online marketing |
| US20040088218A1 (en) * | 2002-11-04 | 2004-05-06 | Abraham Daniel M. | Coupon discounts redemption/cash back program |
| EP1581637A4 (en) | 2002-11-07 | 2007-04-25 | Univ Chicago | MATERIALS AND METHODS WITH HUMAN STEM CELLS |
| US20050003534A1 (en) * | 2002-11-07 | 2005-01-06 | Eliezer Huberman | Human stem cell materials and methods |
| US20040136973A1 (en) * | 2002-11-07 | 2004-07-15 | Eliezer Huberman | Human stem cell materials and methods |
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| US20050260158A1 (en) * | 2003-11-07 | 2005-11-24 | Eliezer Huberman | Human stem cell materials and methods |
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