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NO20084852L - MGLUR5 modulatorer V - Google Patents

MGLUR5 modulatorer V

Info

Publication number
NO20084852L
NO20084852L NO20084852A NO20084852A NO20084852L NO 20084852 L NO20084852 L NO 20084852L NO 20084852 A NO20084852 A NO 20084852A NO 20084852 A NO20084852 A NO 20084852A NO 20084852 L NO20084852 L NO 20084852L
Authority
NO
Norway
Prior art keywords
mglur5 modulators
mglur5
modulators
novel compounds
therapy
Prior art date
Application number
NO20084852A
Other languages
English (en)
Inventor
Abdelmalik Slassi
Tao Xin
Tomislav Stefanac
Louise Edwards
Karolina Nilsson
Methvin Isaac
Peter Dove
Andreas Wallberg
Kenneth Granberg
Saswati Ghosal
Original Assignee
Nps Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nps Pharma Inc filed Critical Nps Pharma Inc
Publication of NO20084852L publication Critical patent/NO20084852L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4196—1,2,4-Triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Den foreliggende oppfinnelse er rettet til nye forbindelser, til en fremgangsmåte for deres fremstilling, deres anvendelse i terapi og farmasøytiske sammensetninger omfattende de nye forbindelsene.
NO20084852A 2006-05-05 2008-11-18 MGLUR5 modulatorer V NO20084852L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US79766306P 2006-05-05 2006-05-05
PCT/US2007/067371 WO2007130824A2 (en) 2006-05-05 2007-04-25 Fused heterocylic compounds and their use as mglur5 modulators

Publications (1)

Publication Number Publication Date
NO20084852L true NO20084852L (no) 2009-01-14

Family

ID=38668441

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20084852A NO20084852L (no) 2006-05-05 2008-11-18 MGLUR5 modulatorer V

Country Status (19)

Country Link
US (1) US20070259860A1 (no)
EP (1) EP2027129A2 (no)
JP (1) JP2009536213A (no)
KR (1) KR20090018935A (no)
CN (1) CN101484455A (no)
AR (1) AR060811A1 (no)
AU (1) AU2007248292A1 (no)
BR (1) BRPI0710980A2 (no)
CA (1) CA2650255A1 (no)
CL (1) CL2007001178A1 (no)
EC (1) ECSP088884A (no)
IL (1) IL194815A0 (no)
MX (1) MX2008013834A (no)
NO (1) NO20084852L (no)
RU (1) RU2008141511A (no)
TW (1) TW200808800A (no)
UY (1) UY30308A1 (no)
WO (1) WO2007130824A2 (no)
ZA (1) ZA200809019B (no)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200821305A (en) 2006-10-05 2008-05-16 Astrazeneca Ab MGluR5 modulators
JP2011500798A (ja) * 2007-10-26 2011-01-06 アストラゼネカ・アクチエボラーグ ｍＧｌｕＲ５のモジュレーターとしてのアミノ１，２，４−トリアゾール誘導体
WO2009054791A1 (en) * 2007-10-26 2009-04-30 Astrazeneca Ab Fused pyrrolidine 1,2,4-triazole derivatives as modulators of mglur5
WO2009054787A1 (en) * 2007-10-26 2009-04-30 Astrazeneca Ab 1,2,4-triazole carboxylic acid derivatives as modulators of mglur5
WO2009054786A1 (en) * 2007-10-26 2009-04-30 Astrazeneca Ab 1,2,4-triazole aryl n-oxides derivatives as modulators of mglur5
TW200922586A (en) * 2007-10-26 2009-06-01 Astrazeneca Ab Thiophene 1,2,4-triazole derivatives as modulators of mGluR5
WO2009054785A1 (en) * 2007-10-26 2009-04-30 Astrazeneca Ab 1,2,4-triazole ether derivatives as modulators of mglur5
WO2009054790A1 (en) * 2007-10-26 2009-04-30 Astrazeneca Ab Amide linked heteroaromatic derivatives as modulators of mglur5
CN102256950A (zh) * 2008-12-18 2011-11-23 阿斯利康(瑞典)有限公司 制备1-[5-(3-氯-苯基)-异噁唑-3-基]-乙酮和(r)-1-[5-(3-氯-苯基)-异噁唑-3-基]-乙醇的新方法
JP5620129B2 (ja) * 2009-03-19 2014-11-05 富士フイルム株式会社 光学フィルム、位相差板、楕円偏光板、液晶表示装置、及び化合物
CA2767764A1 (en) 2009-07-13 2011-01-20 Takeda Pharmaceutical Company Limited Heterocyclic compound and use thereof
ES2443578T3 (es) 2009-12-29 2014-02-19 Eli Lilly And Company Compuestos de tetrahidrotriazolopiridina como potenciadores de receptores selectivos de mGlu5 útiles para el tratamiento de la esquizofrenia
MX2013002511A (es) 2010-09-02 2013-07-29 Takeda Pharmaceutical Triazoles fusionados para el tratamiento o profilaxis de daño cognitivo moderado.
ES2608395T3 (es) 2013-01-23 2017-04-10 Astrazeneca Ab Compuestos químicos
EP2857387A1 (en) 2013-10-07 2015-04-08 Boehringer Ingelheim International Gmbh Process for manufacturing 1,6-dihydro-6-oxo-4-pyridazine carboxylic acid
TWI891782B (zh) 2020-05-06 2025-08-01 德商拜耳廠股份有限公司 作為殺蟲劑之新穎雜芳基三唑化合物

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3896900A (en) * 1999-03-19 2000-10-09 Knoll Pharmaceutical Company Treatment of pain
US20040132726A1 (en) * 2002-08-09 2004-07-08 Astrazeneca Ab And Nps Pharmaceuticals, Inc. New compounds
MXPA05001590A (es) * 2002-08-09 2005-05-23 Astrazeneca Ab Compuestos que tienen actividad en los receptores metabotropicos de glutamato.
BRPI0507498A (pt) * 2004-02-18 2007-07-10 Astrazeneca Ab composto, composição farmacêutica, uso do composto, e, métodos para tratar distúrbios mediados por mglur 5 e para inibir ativação de receptores de mglur 5
KR20070026380A (ko) * 2004-02-18 2007-03-08 아스트라제네카 아베 융합된 헤테로시클릭 화합물 및 대사성 글루타메이트수용체 길항제로서 이들의 용도
US7585881B2 (en) * 2004-02-18 2009-09-08 Astrazeneca Ab Additional heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists

Also Published As

Publication number Publication date
US20070259860A1 (en) 2007-11-08
WO2007130824A3 (en) 2008-05-22
WO2007130824A2 (en) 2007-11-15
AU2007248292A8 (en) 2008-12-04
ZA200809019B (en) 2009-08-26
IL194815A0 (en) 2009-08-03
CL2007001178A1 (es) 2008-01-18
MX2008013834A (es) 2008-11-10
CA2650255A1 (en) 2007-11-15
AU2007248292A1 (en) 2007-11-15
BRPI0710980A2 (pt) 2011-05-31
TW200808800A (en) 2008-02-16
KR20090018935A (ko) 2009-02-24
AR060811A1 (es) 2008-07-16
JP2009536213A (ja) 2009-10-08
UY30308A1 (es) 2007-11-30
EP2027129A2 (en) 2009-02-25
CN101484455A (zh) 2009-07-15
RU2008141511A (ru) 2010-06-20
ECSP088884A (es) 2008-12-30

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