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DK1411118T3 - Celleproliferationsinhibitorer indeholdende anti-glypican-3-antistof - Google Patents

Celleproliferationsinhibitorer indeholdende anti-glypican-3-antistof

Info

Publication number
DK1411118T3
DK1411118T3 DK02741243T DK02741243T DK1411118T3 DK 1411118 T3 DK1411118 T3 DK 1411118T3 DK 02741243 T DK02741243 T DK 02741243T DK 02741243 T DK02741243 T DK 02741243T DK 1411118 T3 DK1411118 T3 DK 1411118T3
Authority
DK
Denmark
Prior art keywords
antibody
glypican
cell proliferation
proliferation inhibitors
containing anti
Prior art date
Application number
DK02741243T
Other languages
English (en)
Inventor
Hiroyuki Aburatani
Tetsuo Nakamura
Masayuki Tsuchiya
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Application granted granted Critical
Publication of DK1411118T3 publication Critical patent/DK1411118T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3076Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells against structure-related tumour-associated moieties
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/732Antibody-dependent cellular cytotoxicity [ADCC]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/734Complement-dependent cytotoxicity [CDC]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Mycology (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
DK02741243T 2001-06-22 2002-06-21 Celleproliferationsinhibitorer indeholdende anti-glypican-3-antistof DK1411118T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2001189443 2001-06-22
PCT/JP2002/006237 WO2003000883A1 (fr) 2001-06-22 2002-06-21 Inhibiteurs de proliferation cellulaire renfermant un anticorps anti-glypicane 3

Publications (1)

Publication Number Publication Date
DK1411118T3 true DK1411118T3 (da) 2008-11-17

Family

ID=19028362

Family Applications (2)

Application Number Title Priority Date Filing Date
DK10003378.6T DK2208784T3 (da) 2001-06-22 2002-06-21 Celleproliferationsinhibitorer indeholdende anti-glypican-3-antistof
DK02741243T DK1411118T3 (da) 2001-06-22 2002-06-21 Celleproliferationsinhibitorer indeholdende anti-glypican-3-antistof

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK10003378.6T DK2208784T3 (da) 2001-06-22 2002-06-21 Celleproliferationsinhibitorer indeholdende anti-glypican-3-antistof

Country Status (14)

Country Link
US (3) US20040236080A1 (da)
EP (3) EP2208784B1 (da)
JP (7) JP4281869B2 (da)
KR (3) KR100953520B1 (da)
CN (2) CN1314803C (da)
AT (2) ATE407204T1 (da)
AU (2) AU2002315857B2 (da)
CA (1) CA2451493C (da)
CY (1) CY1113854T1 (da)
DE (2) DE60228721D1 (da)
DK (2) DK2208784T3 (da)
ES (3) ES2399028T3 (da)
PT (2) PT1411118E (da)
WO (1) WO2003000883A1 (da)

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EP1411118A1 (en) 2004-04-21
ES2353335T3 (es) 2011-03-01
EP2208784B1 (en) 2013-01-02
CN101240022B (zh) 2012-07-18
JP2007051159A (ja) 2007-03-01
KR100877176B1 (ko) 2009-01-07
WO2003000883A1 (fr) 2003-01-03
JP2009161565A (ja) 2009-07-23
DE60228721D1 (en) 2008-10-16
JP2008120828A (ja) 2008-05-29
ES2399028T3 (es) 2013-03-25
CN1314803C (zh) 2007-05-09
US20070172488A1 (en) 2007-07-26
CN1688692A (zh) 2005-10-26
EP1780273A1 (en) 2007-05-02
KR20090107091A (ko) 2009-10-12
US8263077B2 (en) 2012-09-11
JPWO2003000883A1 (ja) 2004-10-07
CA2451493C (en) 2016-08-23
DE60237929D1 (de) 2010-11-18
CY1113854T1 (el) 2016-07-27
HK1079547A1 (en) 2006-04-07
JP2009024020A (ja) 2009-02-05
JP5596935B2 (ja) 2014-09-24
EP1411118A4 (en) 2005-01-26
JP4281869B2 (ja) 2009-06-17
EP1411118B1 (en) 2008-09-03
ATE407204T1 (de) 2008-09-15
AU2007201255A1 (en) 2007-04-19
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JP2007238632A (ja) 2007-09-20
US7744880B2 (en) 2010-06-29
EP1780273B1 (en) 2010-10-06
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DK2208784T3 (da) 2013-03-18
EP2208784A1 (en) 2010-07-21
HK1120522A1 (en) 2009-04-03
PT1411118E (pt) 2008-12-09
CA2451493A1 (en) 2003-01-03
AU2002315857B2 (en) 2007-07-26
ES2312586T3 (es) 2009-03-01
PT2208784E (pt) 2013-04-03
ATE483801T1 (de) 2010-10-15
JP4347402B2 (ja) 2009-10-21
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