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DK1485348T3 - Carbonylamino-derivater som nye inhibitorer af histandeacetylase - Google Patents

Carbonylamino-derivater som nye inhibitorer af histandeacetylase

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Publication number
DK1485348T3
DK1485348T3 DK03708215T DK03708215T DK1485348T3 DK 1485348 T3 DK1485348 T3 DK 1485348T3 DK 03708215 T DK03708215 T DK 03708215T DK 03708215 T DK03708215 T DK 03708215T DK 1485348 T3 DK1485348 T3 DK 1485348T3
Authority
DK
Denmark
Prior art keywords
histane
deacetylase
novel inhibitors
carbonylamino derivatives
carbonylamino
Prior art date
Application number
DK03708215T
Other languages
English (en)
Inventor
Emelen Kristof Van
Marc Gustaaf Celine Verdonck
Brandt Sven Franciscus Anna Van
Leo Jacobus Jozef Backx
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Application granted granted Critical
Publication of DK1485348T3 publication Critical patent/DK1485348T3/da

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/402—1-aryl substituted, e.g. piretanide
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
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CN1305850C (zh) 2002-03-13 2007-03-21 詹森药业有限公司 作为组蛋白脱乙酰酶新颖抑制剂的磺酰基氨基衍生物
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EP1485348B1 (en) 2008-06-11
HRP20040805A2 (en) 2005-04-30
DE60321548D1 (de) 2008-07-24
AR039564A1 (es) 2005-02-23
PL205531B1 (pl) 2010-04-30

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