DK1451143T3 - Fremgangsmåder til fremstilling af O-desmethylvenlafaxin - Google Patents

Fremgangsmåder til fremstilling af O-desmethylvenlafaxin

Info

Publication number: DK1451143T3
Authority: DK; Denmark
Prior art keywords: desmethylvenlafaxine; preparation; methods
Prior art date: 2001-12-04

Application number

DK02804479T

Other languages

Danish (da)

English (en)

Inventor

Beat Theodor Weber

Original Assignee

Wyeth Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-12-04

Filing date

2002-12-03

Publication date

2008-11-10

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23309595&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1451143(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2002-12-03 Application filed by Wyeth Corp filed Critical Wyeth Corp

2008-11-10 Application granted granted Critical

2008-11-10 Publication of DK1451143T3 publication Critical patent/DK1451143T3/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/08—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/10—Separation; Purification; Stabilisation; Use of additives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pain & Pain Management (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

DK02804479T 2001-12-04 2002-12-03 Fremgangsmåder til fremstilling af O-desmethylvenlafaxin DK1451143T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US33495301P	2001-12-04	2001-12-04
PCT/US2002/038403 WO2003048104A1 (en)	2001-12-04	2002-12-03	Methods for preparing o-desmethylvenlafaxine

Publications (1)

Publication Number	Publication Date
DK1451143T3 true DK1451143T3 (da)	2008-11-10

Family

ID=23309595

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK02804479T DK1451143T3 (da)	2001-12-04	2002-12-03	Fremgangsmåder til fremstilling af O-desmethylvenlafaxin

Country Status (28)

Country	Link
US (4)	US6689912B2 (no)
EP (1)	EP1451143B9 (no)
JP (1)	JP4342312B2 (no)
KR (1)	KR100939650B1 (no)
CN (1)	CN1319934C (no)
AR (1)	AR037622A1 (no)
AT (1)	ATE403641T1 (no)
AU (1)	AU2002357049B2 (no)
BR (1)	BR0214701A (no)
CA (1)	CA2466779C (no)
CO (1)	CO5580816A2 (no)
DE (1)	DE60228118D1 (no)
DK (1)	DK1451143T3 (no)
EC (1)	ECSP045135A (no)
ES (1)	ES2311647T4 (no)
HU (1)	HUP0402269A3 (no)
IL (3)	IL162253A0 (no)
MX (1)	MXPA04005309A (no)
NO (1)	NO20042680L (no)
NZ (1)	NZ533316A (no)
PL (1)	PL369299A1 (no)
PT (1)	PT1451143E (no)
RU (1)	RU2317286C2 (no)
SI (1)	SI1451143T1 (no)
TW (1)	TWI260982B (no)
UA (1)	UA80543C2 (no)
WO (1)	WO2003048104A1 (no)
ZA (1)	ZA200405250B (no)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
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US6342533B1 (en)	1998-12-01	2002-01-29	Sepracor, Inc.	Derivatives of (−)-venlafaxine and methods of preparing and using the same
JP2003521470A (ja) *	1999-04-06	2003-07-15	セプラコアインコーポレーテッド	ベンラファキシンの誘導体とその調製および使用方法
DE60221642T3 (de) *	2001-02-12	2017-10-26	Wyeth LLC (n.d.Ges.d. Staates Delaware)	O-desmethyl-venlafaxine succinat salz
UA80543C2 (en) *	2001-12-04	2007-10-10	Wyeth Corp	Method for the preparation of o-desmethylvenlafaxine
AU2006265008A1 (en) *	2005-07-06	2007-01-11	Sepracor Inc.	Combinations of eszopiclone and O-desmethylvenlafaxine, and methods of treatment of menopause and mood, anxiety, and cognitive disorders
AU2006322057A1 (en) *	2005-12-05	2007-06-14	Wyeth	Process for selective synthesis of enantiomers of substituted 1-(2-amino-1-phenyl-ethyl)-cyclohexanols
WO2007071404A1 (en) *	2005-12-20	2007-06-28	Synthon B.V.	Process for making desvenlafaxine
MX2007016179A (es) *	2006-04-17	2008-03-11	Teva Pharma	Formas cristalinas de o-desmetilvenlafaxina.
JP2008546718A (ja) *	2006-04-17	2008-12-25	テバファーマシューティカルインダストリーズリミティド	実質的に純粋なｏ−デスメチルベンラファキシン及びその調製方法。
WO2008035369A2 (en) *	2006-06-30	2008-03-27	Alembic Limited	Novel form of o-desmethyl venlafaxine
US20080221356A1 (en) *	2006-07-26	2008-09-11	Valerie Niddam-Hildesheim	Processes for the synthesis of O-desmethylvenlafaxine
WO2008013994A2 (en)	2006-07-26	2008-01-31	Teva Pharmaceutical Industries Ltd.	Processes for the synthesis of o-desmethylvenlafaxine
US20090137846A1 (en) *	2006-07-26	2009-05-28	Valerie Niddam-Hildesheim	Processes for the synthesis of O-Desmethylvenlafaxine
WO2008013995A2 (en) *	2006-07-26	2008-01-31	Teva Pharmaceutical Industries Ltd.	Tridesmethylvenlafaxine and processes for the synthesis of o-desmethylvenlafaxine
US20090069601A1 (en) *	2006-07-26	2009-03-12	Valerie Niddam-Hildesheim	Processes for the synthesis of O-desmethylvenlafaxine
CA2656166A1 (en) *	2006-07-26	2008-01-31	Teva Pharmaceutical Industries Ltd.	Processes for the synthesis of o-desmethylvenlafaxine
JP2008088159A (ja) *	2006-07-26	2008-04-17	Teva Pharmaceutical Industries Ltd	Ｏ−デスメチルベンラファキシンの合成方法
US20100121108A1 (en) *	2006-08-04	2010-05-13	Medichem, S.A.	Process for synthesizing desvenlafaxine free base and salts or solvates thereof
EP2114862A1 (en) *	2007-01-31	2009-11-11	Merck Generics (UK) Limited	Process for the preparation of o-desmethyl venlafaxine
IN2009DN05509A (no) *	2007-03-14	2010-04-30	Teva Pharma
CA2692738A1 (en) *	2007-07-12	2009-01-15	Dr. Reddy's Laboratories, Ltd.	O-desmethylvenlafaxine
IN2007CH01519A (no) *	2007-07-16	2009-09-11	Matrix Lab Ltd
WO2009034434A2 (en) *	2007-09-10	2009-03-19	Cadila Pharmaceuticals Limited	An improved process for the preparation of o-desmethylvenlafaxine
NZ585368A (en) *	2007-10-26	2012-07-27	Generics Uk Ltd	Process for preparing o-desmethylvenlafaxine
CA2706775A1 (en) *	2007-11-26	2009-06-04	Teva Pharmaceutical Industries Ltd.	Crystal forms of o-desmethylvenlafaxine fumarate
WO2009084038A2 (en) *	2007-12-28	2009-07-09	Ind-Swift Laboratories Limited	Improved process for the preparation of 0-desmethyl-venlafaxine
EP2252574A1 (en) *	2008-03-06	2010-11-24	Teva Pharmaceutical Industries Ltd.	Processes for the preparation of o-desmethylvenlafaxine, free from its dimer impurities
EP2119695A1 (en)	2008-05-16	2009-11-18	Krka	Preparation of O-desmethylvenlafaxine salts
EP2119696A1 (en)	2008-05-16	2009-11-18	Krka	Preparation of O-desmethylvenlafaxine salts
WO2010008735A2 (en) *	2008-06-16	2010-01-21	Teva Pharmaceutical Industries Ltd.	Solid states of o-desmethylvenlaf axine salts
US20100016638A1 (en) *	2008-07-21	2010-01-21	Zdenko Hamersak	Method for preparation of o-desmethylvenlafaxine using polythiolates
US20110263718A1 (en) *	2008-07-30	2011-10-27	Generics [Uk] Limited	Process for the preparation of o-desmethylvenlafaxine
CZ2008756A3 (cs)	2008-11-27	2010-03-24	Zentiva, A. S.	Zpusob prípravy desvenlafaxinu a jeho solí
CZ301820B6 (cs)	2009-02-06	2010-06-30	Zentiva, K.S.	Nové soli desvenlafaxinu a zpusob jejich prípravy
CZ2009454A3 (cs)	2009-07-15	2010-11-10	Zentiva, K. S.	Zpusob prípravy desvenlafaxinu a jeho solí
JP2012532923A (ja)	2009-07-16	2012-12-20	シプラ・リミテッド	Ｏ−デスメチルベンラファキシンの製造方法及びそれに使用される中間体
US20110098506A1 (en) *	2009-10-26	2011-04-28	Intas Pharmaceuticals Limited	Method of preparing o-desmethylvenlafaxine
US20110184067A1 (en) *	2010-01-25	2011-07-28	Intas Pharmaceuticals Ltd.	O-desmethylvenlafaxine succinate polymorph & process for preparing thereof
KR101409554B1 (ko) *	2010-03-29	2014-06-19	플리바 흐르바츠카 디.오.오.	Ｏ-데스메틸벤라팍신 푸마레이트의 결정형
CZ303249B6 (cs)	2010-04-06	2012-06-20	Zentiva, K.S.	Zpusob výroby 4-(2-(substituovaných)-1-(1-hydroxycyklohexyl)ethyl)fenolu O-demethylací jejich methyletheru pomocí nepáchnoucích aromatických thiolu
EP2394976A1 (en)	2010-06-11	2011-12-14	LEK Pharmaceuticals d.d.	Process for demethylating aromatic methyl ethers using 3-mercaptopropionic acid
EP3580198B1 (en)	2017-02-09	2023-08-09	R L Finechem Private Limited	A process for preparation of1-[2-(dimethylamino)-1-(4-hydroxyphenyl) ethyl]-cyclohexanol and salts thereof
CN109232189B (zh) *	2018-09-25	2021-10-08	杭州盛弗泰新材料科技有限公司	一种高纯度1-羟基芘的制备方法
CN109665966A (zh) *	2018-11-01	2019-04-23	山东蒲济医药科技有限公司	一种琥珀酸去甲文拉法辛化合物的制备方法

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DE2741009A1 (de) *	1976-09-22	1978-03-23	Sandoz Ag	4-styryl-4-indolinol-derivate, ihre verwendung und herstellung
US4535186A (en)	1983-04-19	1985-08-13	American Home Products Corporation	2-Phenyl-2-(1-hydroxycycloalkyl or 1-hydroxycycloalk-2-enyl)ethylamine derivatives
CA1227304A (en)	1984-08-01	1987-09-29	Raymond C. Francis	Delignification of pulp
GB8902209D0 (en)	1989-02-01	1989-03-22	Wyeth John And Brother Limited	Preparation of cyclohexanol derivatives and novel thioamide intermediates
US6197828B1 (en) *	1998-12-01	2001-03-06	Sepracor, Inc.	Derivatives of (+)-venlafaxine and methods of preparing and using the same
US6342533B1 (en) *	1998-12-01	2002-01-29	Sepracor, Inc.	Derivatives of (−)-venlafaxine and methods of preparing and using the same
JP2003521470A (ja)	1999-04-06	2003-07-15	セプラコアインコーポレーテッド	ベンラファキシンの誘導体とその調製および使用方法
AU5738700A (en)	1999-06-15	2001-01-02	American Home Products Corporation	Enantiomers of o-desmethyl venlafaxine
AU2001281967A1 (en)	2000-07-18	2002-01-30	Bayer Aktiengesellschaft	Regulation of human desc1-like serine protease
DE60221642T3 (de) *	2001-02-12	2017-10-26	Wyeth LLC (n.d.Ges.d. Staates Delaware)	O-desmethyl-venlafaxine succinat salz
UA80543C2 (en)	2001-12-04	2007-10-10	Wyeth Corp	Method for the preparation of o-desmethylvenlafaxine

2002
- 2002-03-12 UA UA20040705306A patent/UA80543C2/uk unknown
- 2002-11-26 US US10/304,871 patent/US6689912B2/en not_active Expired - Fee Related
- 2002-11-27 TW TW091134427A patent/TWI260982B/zh not_active IP Right Cessation
- 2002-12-03 PL PL02369299A patent/PL369299A1/xx unknown
- 2002-12-03 DE DE60228118T patent/DE60228118D1/de not_active Expired - Lifetime
- 2002-12-03 AU AU2002357049A patent/AU2002357049B2/en not_active Ceased
- 2002-12-03 MX MXPA04005309A patent/MXPA04005309A/es active IP Right Grant
- 2002-12-03 JP JP2003549297A patent/JP4342312B2/ja not_active Expired - Fee Related
- 2002-12-03 IL IL16225302A patent/IL162253A0/xx active IP Right Grant
- 2002-12-03 WO PCT/US2002/038403 patent/WO2003048104A1/en not_active Ceased
- 2002-12-03 AR ARP020104669A patent/AR037622A1/es unknown
- 2002-12-03 SI SI200230743T patent/SI1451143T1/sl unknown
- 2002-12-03 KR KR1020047008512A patent/KR100939650B1/ko not_active Expired - Fee Related
- 2002-12-03 HU HU0402269A patent/HUP0402269A3/hu active IP Right Revival
- 2002-12-03 EP EP02804479A patent/EP1451143B9/en not_active Expired - Lifetime
- 2002-12-03 CA CA2466779A patent/CA2466779C/en not_active Expired - Lifetime
- 2002-12-03 DK DK02804479T patent/DK1451143T3/da active
- 2002-12-03 BR BR0214701-7A patent/BR0214701A/pt not_active Application Discontinuation
- 2002-12-03 PT PT02804479T patent/PT1451143E/pt unknown
- 2002-12-03 RU RU2004120284/04A patent/RU2317286C2/ru not_active IP Right Cessation
- 2002-12-03 ES ES02804479T patent/ES2311647T4/es not_active Expired - Lifetime
- 2002-12-03 AT AT02804479T patent/ATE403641T1/de not_active IP Right Cessation
- 2002-12-03 NZ NZ533316A patent/NZ533316A/en unknown
- 2002-12-03 CN CNB028242386A patent/CN1319934C/zh not_active Expired - Fee Related
2003
- 2003-12-31 US US10/750,196 patent/US20040158101A1/en not_active Abandoned
2004
- 2004-05-31 IL IL162253A patent/IL162253A/en not_active IP Right Cessation
- 2004-06-01 CO CO04050957A patent/CO5580816A2/es active IP Right Grant
- 2004-06-04 EC EC2004005135A patent/ECSP045135A/es unknown
- 2004-06-25 NO NO20042680A patent/NO20042680L/no not_active Application Discontinuation
- 2004-07-01 ZA ZA2004/05250A patent/ZA200405250B/en unknown
2007
- 2007-06-01 US US11/756,772 patent/US7435854B2/en not_active Expired - Fee Related
2008
- 2008-09-11 US US12/208,990 patent/US20090018365A1/en not_active Abandoned
- 2008-09-11 IL IL194034A patent/IL194034A/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
PT1451143E (pt)	2008-10-21
HK1065778A1 (en)	2005-03-04
PL369299A1 (en)	2005-04-18
HUP0402269A3 (en)	2010-06-28
US20070225525A1 (en)	2007-09-27
KR20050044671A (ko)	2005-05-12
NZ533316A (en)	2005-12-23
CA2466779C (en)	2013-11-19
US6689912B2 (en)	2004-02-10
MXPA04005309A (es)	2004-09-13
RU2004120284A (ru)	2005-04-10
TWI260982B (en)	2006-09-01
ES2311647T3 (es)	2009-02-16
AU2002357049B2 (en)	2009-07-16
ECSP045135A (es)	2004-07-23
HUP0402269A2 (hu)	2005-02-28
WO2003048104A1 (en)	2003-06-12
US20040158101A1 (en)	2004-08-12
DE60228118D1 (de)	2008-09-18
NO20042680L (no)	2004-06-25
AR037622A1 (es)	2004-11-17
IL162253A (en)	2009-02-11
JP4342312B2 (ja)	2009-10-14
RU2317286C2 (ru)	2008-02-20
SI1451143T1 (sl)	2008-12-31
EP1451143A1 (en)	2004-09-01
EP1451143B9 (en)	2009-08-12
ATE403641T1 (de)	2008-08-15
AU2002357049A1 (en)	2003-06-17
JP2005511681A (ja)	2005-04-28
US20090018365A1 (en)	2009-01-15
US20030105358A1 (en)	2003-06-05
ES2311647T4 (es)	2009-11-10
TW200301102A (en)	2003-07-01
CA2466779A1 (en)	2003-06-12
KR100939650B1 (ko)	2010-02-05
EP1451143B1 (en)	2008-08-06
CN1319934C (zh)	2007-06-06
CN1625546A (zh)	2005-06-08
CO5580816A2 (es)	2005-11-30
IL194034A (en)	2010-12-30
UA80543C2 (en)	2007-10-10
BR0214701A (pt)	2004-08-31
ZA200405250B (en)	2005-12-28
IL162253A0 (en)	2005-11-20
US7435854B2 (en)	2008-10-14

Publication	Publication Date	Title
DK1451143T3 (da)	2008-11-10	Fremgangsmåder til fremstilling af O-desmethylvenlafaxin
DK1277722T3 (da)	2005-04-25	Fremgangsmåde til fremstilling af methanol
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IS2940B (is)	2016-03-15	Mótefni gegn CD40
CY2007029I1 (el)	2009-11-04	Μεθοδος για την παρασκευη υποκατεστημενων οκτανοϋλ-αμιδιων
DK1309545T3 (da)	2007-10-29	Fremgangsmåde til fremstilling af alkylarylsulfonater
DK1840125T3 (da)	2009-11-09	Mellemprodukter til fremstilling af dioxan-2-alkylcarbamater
DK1380121T3 (da)	2007-12-27	Fremgangsmåde til fremstilling af oxazolidinoner
DK1309581T3 (da)	2005-03-14	Fremgangsmåde til fremstilling af citalopram
DK1448205T3 (da)	2011-12-12	Kombinationer til behandling af immunoinflammatoriske sygdomme
DK1392318T3 (da)	2007-06-25	15-keto-prostaglandiner til behandling af lægemiddelinduceret forstoppelse
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DK1296970T3 (da)	2008-07-14	Fremgangsmåde til fremstilling af citalopram
DK1292586T3 (da)	2004-08-30	Fremgangsmåde til fremstilling af pyrazolopyrimidinoner
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DE60227896D1 (de)	2008-09-11	Verfahen zur Herstellung von Polyalkylphenoxyaminoalkanen
ITMI20031994A1 (it)	2005-04-16	Procedimento per la preparazione di fludarabina fosfato