DK1448198T3 - Nicotin- eller isonicotin-benzothiazolderivater - Google Patents

Nicotin- eller isonicotin-benzothiazolderivater

Info

Publication number: DK1448198T3
Authority: DK; Denmark
Prior art keywords: isonicotine; nicotine; benzothiazole derivatives; benzothiazole; derivatives
Prior art date: 2001-11-19

Application number

DK02787632T

Other languages

Danish (da)

English (en)

Inventor

Alexander Flohr

Roland Jakob-Roetne

Roger David Norcross

Claus Riemer

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-11-19

Filing date

2002-11-11

Publication date

2008-01-07

2002-11-11 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

2008-01-07 Application granted granted Critical

2008-01-07 Publication of DK1448198T3 publication Critical patent/DK1448198T3/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Addiction (AREA)
Psychiatry (AREA)
Cardiology (AREA)
Pulmonology (AREA)
Heart & Thoracic Surgery (AREA)
Pain & Pain Management (AREA)
Hospice & Palliative Care (AREA)
Psychology (AREA)
Immunology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Rheumatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

DK02787632T 2001-11-19 2002-11-11 Nicotin- eller isonicotin-benzothiazolderivater DK1448198T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP01127312		2001-11-19
PCT/EP2002/012562 WO2003043636A1 (en)	2001-11-19	2002-11-11	Nicotin-or isonicotin benzothiazole derivatives

Publications (1)

Publication Number	Publication Date
DK1448198T3 true DK1448198T3 (da)	2008-01-07

Family

ID=8179263

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK02787632T DK1448198T3 (da)	2001-11-19	2002-11-11	Nicotin- eller isonicotin-benzothiazolderivater

Country Status (38)

Country	Link
US (1)	US6620811B2 (es)
EP (1)	EP1448198B1 (es)
JP (1)	JP4226474B2 (es)
KR (1)	KR100577110B1 (es)
CN (1)	CN100546580C (es)
AR (1)	AR039367A1 (es)
AT (1)	ATE376831T1 (es)
AU (1)	AU2002351955B2 (es)
BR (1)	BR0214245A (es)
CA (1)	CA2467552C (es)
DE (1)	DE60223278T2 (es)
DK (1)	DK1448198T3 (es)
EA (1)	EA007502B1 (es)
EC (1)	ECSP045109A (es)
ES (1)	ES2294187T3 (es)
GT (1)	GT200200232A (es)
HR (1)	HRP20040396A2 (es)
HU (1)	HUP0402161A3 (es)
IL (2)	IL161623A0 (es)
JO (1)	JO2290B1 (es)
MA (1)	MA27083A1 (es)
MX (1)	MXPA04004684A (es)
MY (1)	MY126176A (es)
NO (1)	NO20042576L (es)
NZ (1)	NZ532802A (es)
PA (1)	PA8558001A1 (es)
PE (1)	PE20030713A1 (es)
PL (1)	PL369517A1 (es)
PT (1)	PT1448198E (es)
RS (1)	RS39904A (es)
RU (1)	RU2294933C2 (es)
SI (1)	SI1448198T1 (es)
TN (1)	TNSN04087A1 (es)
TW (1)	TW200407134A (es)
UA (1)	UA77462C2 (es)
UY (1)	UY27542A1 (es)
WO (1)	WO2003043636A1 (es)
ZA (1)	ZA200403817B (es)

Families Citing this family (38)

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JP3886897B2 (ja) *	2000-06-21	2007-02-28	エフ．ホフマン−ラロシュアーゲー	ベンゾチアゾール誘導体
ATE491474T1 (de) *	2001-06-07	2011-01-15	Sang Christine Dr	Behandlung von neuropathischen schmerzen mittels eines n-methyl-d-aspartate (nmda)-rezeptor- antagonists
US6734179B2 (en) *	2001-12-12	2004-05-11	Hoffmann-La Roche Inc.	Benzothiazoles
US7390813B1 (en)	2001-12-21	2008-06-24	Xenon Pharmaceuticals Inc.	Pyridylpiperazines and aminonicotinamides and their use as therapeutic agents
US20050119251A1 (en) *	2001-12-21	2005-06-02	Jian-Min Fu	Nicotinamide derivatives and their use as therapeutic agents
US6872833B2 (en) *	2003-04-14	2005-03-29	Hoffmann-La Roche Inc.	Adenosine receptor ligands
BRPI0412805A (pt) *	2003-07-23	2006-09-26	Synta Pharmaceuticals Corp	método para modular canais de ìon de cálcio ativado por liberação de ìon de cálcio
TWI345974B (en)	2003-07-30	2011-08-01	Xenon Pharmaceuticals Inc	Pyridazine derivatives and their use in the inhibition of stearoyl-coa desaturase
BRPI0414266A (pt) *	2003-09-19	2006-11-07	Hoffmann La Roche	derivados de tiazolopiridina como ligandos receptores da adenosina
JP4842829B2 (ja) *	2003-10-31	2011-12-21	武田薬品工業株式会社	含窒素縮合複素環化合物
JP4638355B2 (ja)	2003-12-26	2011-02-23	協和発酵キリン株式会社	チアゾール誘導体
AU2004321997A1 (en) *	2004-07-06	2006-02-09	Xenon Pharmaceuticals Inc.	Nicotinamide derivatives and their use as therapeutic agents
JP2008506735A (ja) *	2004-07-22	2008-03-06	エフ．ホフマン−ラ　ロシュ　アーゲー	置換されているベンゾチアゾール類
KR100823799B1 (ko) *	2004-07-22	2008-04-21	에프. 호프만-라 로슈 아게	벤조티아졸 유도체
JP5202946B2 (ja) *	2004-07-22	2013-06-05	エフ．ホフマン−ラロシュアーゲー	ベンゾチアゾール誘導体
AU2005286790A1 (en) *	2004-09-20	2006-03-30	Xenon Pharmaceuticals Inc.	Bicyclic heterocyclic derivatives and their use as inhibitors of stearoyl-CoA-desaturase (SCD)
TW200626155A (en) *	2004-09-20	2006-08-01	Xenon Pharmaceuticals Inc	Heterocyclic derivatives and their use as therapeutic agents
AU2005286728A1 (en) *	2004-09-20	2006-03-30	Xenon Pharmaceuticals Inc.	Heterocyclic derivatives and their use as mediators of stearoyl-CoA desaturase
JP4958785B2 (ja)	2004-09-20	2012-06-20	ゼノン・ファーマシューティカルズ・インコーポレイテッド	複素環誘導体およびステアロイル−ＣｏＡデサチュラーゼインヒビターとしてのそれらの使用
WO2006034441A1 (en) *	2004-09-20	2006-03-30	Xenon Pharmaceuticals Inc.	Heterocyclic derivatives and their use as stearoyl-coa desaturase inhibitors
CA2580855A1 (en) *	2004-09-20	2006-03-30	Xenon Pharmaceuticals Inc.	Heterocyclic derivatives and their use as stearoyl-coa desaturase inhibitors
ES2359840T5 (es) †	2004-09-20	2015-03-25	Xenon Pharmaceuticals Inc.	Derivados de piridina para inhibición de estearoil-CoA-desaturasa humana
BRPI0515483A (pt)	2004-09-20	2008-07-22	Xenon Pharmaceuticals Inc	derivados heterocìclicos para o tratamento de doenças mediadas por enzimas estearoil-coa desaturase
CN101084211A (zh) *	2004-09-20	2007-12-05	泽农医药公司	杂环衍生物及其作为治疗剂的用途
US7459563B2 (en) *	2004-11-05	2008-12-02	Hoffmann-La Roche Inc.	Process for the preparation of isonicotinic acid derivatives
US7893267B2 (en) *	2005-03-14	2011-02-22	High Point Pharmaceuticals, Llc	Benzazole derivatives, compositions, and methods of use as β-secretase inhibitors
WO2007130075A1 (en) *	2005-06-03	2007-11-15	Xenon Pharmaceuticals Inc.	Aminothiazole derivatives as human stearoyl-coa desaturase inhibitors
MX2009004314A (es) *	2006-11-13	2009-05-05	Pfizer Prod Inc	Diaril, dipiridinil y arilpiridinilderivados y usos de los mismos.
JP2012525389A (ja)	2009-04-27	2012-10-22	ハイポイントファーマシューティカルズ，リミティドライアビリティカンパニー	置換イソキノリン誘導体、医薬組成物、及びβ−セクレターゼ阻害剤としての使用方法
TWI548411B (zh)	2009-04-28	2016-09-11	Kyowa Hakko Kirin Co Ltd	Exercise disorder treatment
UA110097C2 (uk)	2009-09-02	2015-11-25		Терапевтичний агент для лікування розладів настрою
UA113383C2 (xx)	2009-09-02	2017-01-25		Терапевтичний агент для лікування тривожних розладів
US8450354B2 (en) *	2010-03-23	2013-05-28	High Point Pharmaceuticals, Llc	Substituted imidazo[1,2-b]pyridazine derivatives, pharmaceutical compositions, and methods of use as β-secretase inhibitors
JP5248585B2 (ja) *	2010-12-15	2013-07-31	ゼノン・ファーマシューティカルズ・インコーポレイテッド	治療薬としてのニコチンアミド誘導体およびそれらの使用
DE102011005232A1 (de)	2011-03-08	2012-09-13	AristoCon GmbH & Co. KG	Adenosin und seine Derivate zur Verwendung in der Schmerztherapie
PE20150998A1 (es)	2012-10-02	2015-06-29	Epitherapeutics Aps	Inhibidores de histona demetilasas
WO2020103930A1 (zh) *	2018-11-22	2020-05-28	上海科技大学	噻唑并环类化合物、其制备方法、中间体和应用
DE102019110904B4 (de) *	2019-04-26	2022-01-20	Helmholtz-Zentrum Dresden - Rossendorf E. V.	N-(4-methoxy-7-morpholinobenzo[d]thiazol-2-yl)-acetamid-Derivate und deren Verwendung

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EP0113219B1 (en)	1982-12-21	1987-11-19	Johnsen & Jorgensen (Plastics) Limited	Dispensing container
FI91859C (fi)	1987-06-17	1994-08-25	Eisai Co Ltd	Analogiamenetelmä antiallergisena aineena aktiivisen bentsotiatsolijohdannaisen valmistamiseksi
IL90337A0 (en) *	1988-05-24	1989-12-15	Pfizer	Aromatic and heterocyclic carboxamide derivatives as antineoplastic agents
JP3886897B2 (ja) *	2000-06-21	2007-02-28	エフ．ホフマン−ラロシュアーゲー	ベンゾチアゾール誘導体

2002
- 2002-11-05 US US10/288,100 patent/US6620811B2/en not_active Expired - Lifetime
- 2002-11-11 DK DK02787632T patent/DK1448198T3/da active
- 2002-11-11 KR KR1020047007638A patent/KR100577110B1/ko not_active Expired - Fee Related
- 2002-11-11 UA UA20040604552A patent/UA77462C2/uk unknown
- 2002-11-11 HR HR20040396A patent/HRP20040396A2/hr not_active Application Discontinuation
- 2002-11-11 BR BR0214245-7A patent/BR0214245A/pt not_active IP Right Cessation
- 2002-11-11 CA CA2467552A patent/CA2467552C/en not_active Expired - Fee Related
- 2002-11-11 CN CNB028228391A patent/CN100546580C/zh not_active Expired - Fee Related
- 2002-11-11 ES ES02787632T patent/ES2294187T3/es not_active Expired - Lifetime
- 2002-11-11 RU RU2004118425/04A patent/RU2294933C2/ru not_active IP Right Cessation
- 2002-11-11 MX MXPA04004684A patent/MXPA04004684A/es active IP Right Grant
- 2002-11-11 EP EP02787632A patent/EP1448198B1/en not_active Expired - Lifetime
- 2002-11-11 AU AU2002351955A patent/AU2002351955B2/en not_active Ceased
- 2002-11-11 DE DE60223278T patent/DE60223278T2/de not_active Expired - Lifetime
- 2002-11-11 NZ NZ532802A patent/NZ532802A/en unknown
- 2002-11-11 PL PL02369517A patent/PL369517A1/xx not_active Application Discontinuation
- 2002-11-11 PT PT02787632T patent/PT1448198E/pt unknown
- 2002-11-11 WO PCT/EP2002/012562 patent/WO2003043636A1/en not_active Ceased
- 2002-11-11 IL IL16162302A patent/IL161623A0/xx unknown
- 2002-11-11 SI SI200230637T patent/SI1448198T1/sl unknown
- 2002-11-11 EA EA200400598A patent/EA007502B1/ru not_active IP Right Cessation
- 2002-11-11 HU HU0402161A patent/HUP0402161A3/hu not_active Application Discontinuation
- 2002-11-11 JP JP2003545317A patent/JP4226474B2/ja not_active Expired - Fee Related
- 2002-11-11 RS YU39904A patent/RS39904A/sr unknown
- 2002-11-11 AT AT02787632T patent/ATE376831T1/de active
- 2002-11-14 PA PA20028558001A patent/PA8558001A1/es unknown
- 2002-11-14 TW TW091133371A patent/TW200407134A/zh unknown
- 2002-11-15 PE PE2002001104A patent/PE20030713A1/es not_active Application Discontinuation
- 2002-11-18 AR ARP020104416A patent/AR039367A1/es unknown
- 2002-11-18 MY MYPI20024303A patent/MY126176A/en unknown
- 2002-11-18 GT GT200200232A patent/GT200200232A/es unknown
- 2002-11-18 UY UY27542A patent/UY27542A1/es not_active Application Discontinuation
- 2002-11-18 JO JO2002114A patent/JO2290B1/en active
2004
- 2004-04-26 IL IL161623A patent/IL161623A/en not_active IP Right Cessation
- 2004-05-17 EC EC2004005109A patent/ECSP045109A/es unknown
- 2004-05-18 TN TNP2004000087A patent/TNSN04087A1/en unknown
- 2004-05-18 ZA ZA200403817A patent/ZA200403817B/en unknown
- 2004-05-18 MA MA27681A patent/MA27083A1/fr unknown
- 2004-06-18 NO NO20042576A patent/NO20042576L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
EP1448198A1 (en)	2004-08-25
PA8558001A1 (es)	2003-07-28
JP2005522413A (ja)	2005-07-28
NO20042576L (no)	2004-06-18
HUP0402161A3 (en)	2010-06-28
MA27083A1 (fr)	2004-12-20
ECSP045109A (es)	2004-06-28
GT200200232A (es)	2003-06-17
WO2003043636A1 (en)	2003-05-30
US6620811B2 (en)	2003-09-16
RS39904A (sr)	2006-10-27
DE60223278T2 (de)	2008-08-14
ATE376831T1 (de)	2007-11-15
IL161623A0 (en)	2004-09-27
EA200400598A1 (ru)	2005-02-24
PT1448198E (pt)	2007-12-11
ZA200403817B (en)	2005-05-23
EP1448198B1 (en)	2007-10-31
ES2294187T3 (es)	2008-04-01
CA2467552C (en)	2011-05-24
KR100577110B1 (ko)	2006-05-10
AU2002351955B2 (en)	2007-03-15
PL369517A1 (en)	2005-04-18
HRP20040396A2 (en)	2005-04-30
DE60223278D1 (de)	2007-12-13
UA77462C2 (en)	2006-12-15
RU2004118425A (ru)	2006-01-10
TNSN04087A1 (en)	2006-06-01
EA007502B1 (ru)	2006-10-27
JP4226474B2 (ja)	2009-02-18
UY27542A1 (es)	2003-05-30
TW200407134A (en)	2004-05-16
CN1617722A (zh)	2005-05-18
JO2290B1 (en)	2005-09-12
SI1448198T1 (sl)	2008-02-29
CA2467552A1 (en)	2003-05-30
IL161623A (en)	2010-11-30
KR20050044535A (ko)	2005-05-12
CN100546580C (zh)	2009-10-07
BR0214245A (pt)	2004-12-14
PE20030713A1 (es)	2003-08-23
MXPA04004684A (es)	2004-08-12
US20030134854A1 (en)	2003-07-17
NZ532802A (en)	2005-07-29
HUP0402161A2 (hu)	2005-02-28
AU2002351955A1 (en)	2003-06-10
MY126176A (en)	2006-09-29
RU2294933C2 (ru)	2007-03-10
AR039367A1 (es)	2005-02-16

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ATE382601T1 (de)	2008-01-15	Substituierte 4-aminocyclohexanolderivate
DK1392670T3 (da)	2005-08-08	Substituerede C-furan-2-yl-methylamin- og C-thiophen-2-yl-methylamin-derivater
DE60202381D1 (de)	2005-01-27	Paroxetin-n-formyl-derivate
ATE374776T1 (de)	2007-10-15	Pyrrolotriazolopyrimidinonderivate
NO20024393D0 (no)	2002-09-13	2-fenylpyran-4-on-derivater
DE60219659D1 (de)	2007-05-31	Heterocyclische retioidverbindungen