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DK1383489T3 - Carbamatforbindelser til anvendelse ved forebyggelse eller behandling af neurodegeneative sygdomme - Google Patents

Carbamatforbindelser til anvendelse ved forebyggelse eller behandling af neurodegeneative sygdomme

Info

Publication number
DK1383489T3
DK1383489T3 DK02714977T DK02714977T DK1383489T3 DK 1383489 T3 DK1383489 T3 DK 1383489T3 DK 02714977 T DK02714977 T DK 02714977T DK 02714977 T DK02714977 T DK 02714977T DK 1383489 T3 DK1383489 T3 DK 1383489T3
Authority
DK
Denmark
Prior art keywords
prevention
treatment
neurodegenerative diseases
carbamate compounds
carbamate
Prior art date
Application number
DK02714977T
Other languages
Danish (da)
English (en)
Inventor
Boyu Zhao
Carlos R Plata-Salaman
Roy E Twyman
Original Assignee
Ortho Mcneil Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Mcneil Pharm Inc filed Critical Ortho Mcneil Pharm Inc
Application granted granted Critical
Publication of DK1383489T3 publication Critical patent/DK1383489T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/325Carbamic acids; Thiocarbamic acids; Anhydrides or salts thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Psychology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Vascular Medicine (AREA)
  • Pulmonology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK02714977T 2001-02-27 2002-02-21 Carbamatforbindelser til anvendelse ved forebyggelse eller behandling af neurodegeneative sygdomme DK1383489T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US27168201P 2001-02-27 2001-02-27
PCT/US2002/005541 WO2002067925A1 (fr) 2001-02-27 2002-02-21 Composes a base de carbamate destines a etre utilises dans la prevention ou le traitement de troubles neurodegeneratifs
US10/081,764 US20020165273A1 (en) 2001-02-27 2002-02-21 Carbamate compounds for use in preventing or treating neurodegenerative disorders

Publications (1)

Publication Number Publication Date
DK1383489T3 true DK1383489T3 (da) 2007-08-06

Family

ID=26765943

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02714977T DK1383489T3 (da) 2001-02-27 2002-02-21 Carbamatforbindelser til anvendelse ved forebyggelse eller behandling af neurodegeneative sygdomme

Country Status (26)

Country Link
US (3) US20020165273A1 (fr)
EP (1) EP1383489B1 (fr)
JP (1) JP4276840B2 (fr)
KR (1) KR100910928B1 (fr)
CN (1) CN1235579C (fr)
AR (1) AR035756A1 (fr)
AT (1) ATE361745T1 (fr)
BR (1) BR0207645A (fr)
CA (1) CA2439295C (fr)
CY (1) CY1106753T1 (fr)
CZ (1) CZ301203B6 (fr)
DE (1) DE60220043T2 (fr)
DK (1) DK1383489T3 (fr)
ES (1) ES2284845T3 (fr)
HU (1) HUP0303264A3 (fr)
IL (2) IL157591A0 (fr)
MX (1) MXPA03007718A (fr)
MY (1) MY138156A (fr)
NO (1) NO20033798L (fr)
NZ (1) NZ527990A (fr)
PL (1) PL364680A1 (fr)
PT (1) PT1383489E (fr)
RS (1) RS51055B (fr)
RU (1) RU2300373C2 (fr)
TW (1) TWI312679B (fr)
WO (1) WO2002067925A1 (fr)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7470798B2 (en) * 2003-09-19 2008-12-30 Edison Pharmaceuticals, Inc. 7,8-bicycloalkyl-chroman derivatives
CN101056629B (zh) * 2004-09-16 2012-01-11 詹森药业有限公司 2-苯基-1,2-乙二醇-(二)氨基甲酸酯在制备治疗癫痫发生的药物中的用途
JP2008516961A (ja) * 2004-10-15 2008-05-22 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ 神経変性障害を処置することにおける使用のためのカルバメート化合物
US20070021500A1 (en) * 2005-07-12 2007-01-25 Twyman Roy E Methods for neuroprotection
CN101272776B (zh) * 2005-07-26 2012-10-03 詹森药业有限公司 氨基甲酸酯在制备治疗物质滥用相关疾病药物中的用途
KR20090076958A (ko) * 2006-10-06 2009-07-13 얀센 파마슈티카 엔.브이. 신규 (s)-(+)-2-(2-클로로페닐)-2-하이드록시-에틸 카바메이트 결정
US20080317883A1 (en) * 2006-10-30 2008-12-25 Yong Moon Choi Methods for treating depression
MX2009004798A (es) * 2006-10-31 2009-08-12 Janssen Pharmaceutica Nv Tratamiento de los trastornos generalizados del desarrollo.
US9018253B2 (en) 2010-07-02 2015-04-28 Bio-Pharm Solutions Co., Ltd. Phenylcarbamate compound and muscle relaxant containing the same
JP5774694B2 (ja) * 2010-07-02 2015-09-09 バイオ−ファーム ソリューションズ カンパニー リミテッド フェニルカルバメート化合物およびこれを含む筋肉弛緩剤
US8609849B1 (en) 2010-11-30 2013-12-17 Fox Chase Chemical Diversity Center, Inc. Hydroxylated sulfamides exhibiting neuroprotective action and their method of use
WO2013036678A1 (fr) * 2011-09-07 2013-03-14 Satori Pharmaceuticals, Inc. Composés utiles pour le traitement de maladies neurodégénératives
EP2797881B1 (fr) 2011-12-27 2018-11-14 Bio-Pharm Solutions Co., Ltd. Composé de dérivés de carbamate d'alkyle phényle et composition pharmaceutique le contenant
JP6062077B2 (ja) 2013-03-12 2017-01-18 バイオ−ファーム ソリューションズ カンパニー リミテッド 小児てんかん及びてんかん関連症侯群の予防又は治療用フェニルカルバメート化合物{phenylcarbamatecompoundsforuseinpreventingortreatingpediatricepilesyandepilesy−relatedsyndromes}
CN105164103B (zh) * 2013-03-12 2019-12-06 比皮艾思药物研发有限公司 苯基氨基甲酸酯化合物和含有其的预防或治疗记忆缺失相关疾病的组合物
KR102121680B1 (ko) * 2016-02-29 2020-06-10 (주)바이오팜솔루션즈 설파메이트 유도체 화합물, 이의 제조 방법 및 용도
US11147798B2 (en) 2016-12-14 2021-10-19 Sk Biopharmaceuticals Co., Ltd. Use of carbamate compound for prevention, alleviation, or treatment of demyelinating disease
US20220117941A1 (en) * 2018-09-21 2022-04-21 Sk Biopharmaceuticals Co., Ltd. Carbamate compound and use of formulation comprising same in preventing, alleviating, or treating acute stress disorder or post-traumatic stress disorder
BR112023003473A2 (pt) * 2020-08-31 2023-04-11 Bio Pharm Solutions Co Ltd Compostos de carbamato de alquil fenila para o uso na prevenção ou no tratamento de doença neurodegenerativa
BR112023004354A2 (pt) 2020-09-10 2023-04-04 Bio Pharm Solutions Co Ltd Compostos derivados de sulfamato para uso no tratamento ou alívio de um transtorno psiquiátrico

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3313692A (en) * 1958-04-21 1967-04-11 Armour Pharma Method of inducing calming and muscle relaxation with carbamates
US3278380A (en) * 1962-02-06 1966-10-11 Armour Pharma Methods of calming employing diphenyl hydroxy carbamate compounds
US3265728A (en) * 1962-07-18 1966-08-09 Armour Pharma Substituted phenethyl carbamates
US5474990A (en) * 1989-10-20 1995-12-12 Olney; John W. Barbiturates as safening agents in conjunction with NMDA antagonists
CN1109880A (zh) * 1994-02-03 1995-10-11 合成实验室公司 3-(2-氨基乙基)-4-[3-(三氟甲基)苯甲酰基]-3,4-二氢-2h-1,4-苯并噁嗪衍生物、制备及其应用
US5492930A (en) * 1994-04-25 1996-02-20 Schering Corporation Method and formulation for treating CNS disorders
US5698588A (en) * 1996-01-16 1997-12-16 Yukong Limited Halogen substituted carbamate compounds from 2-phenyl-1,2-ethanediol
US5728728A (en) * 1996-04-10 1998-03-17 Kozachuk; Walter E. Methods of providing neuroprotection
US6232434B1 (en) * 1996-08-02 2001-05-15 Duke University Medical Center Polymers for delivering nitric oxide in vivo
KR100886578B1 (ko) * 2001-02-27 2009-03-05 오르토-맥네일 파마슈티칼, 인코퍼레이티드 카바메이트 화합물을 포함하는 정신증 장애 예방용 또는 치료용 약제학적 조성물
ATE369130T1 (de) * 2001-02-27 2007-08-15 Ortho Mcneil Pharm Inc Carbamatverbindungen zur vorbeugung und behandlung von bewegungsstörungen
CN1250215C (zh) * 2001-02-27 2006-04-12 奥索-麦克尼尔药品公司 用于预防或治疗双相性精神障碍的氨基甲酸酯化合物

Also Published As

Publication number Publication date
HK1065486A1 (en) 2005-02-25
NO20033798D0 (no) 2003-08-26
RS51055B (sr) 2010-10-31
AR035756A1 (es) 2004-07-07
JP4276840B2 (ja) 2009-06-10
IL157591A (en) 2009-12-24
NZ527990A (en) 2006-01-27
CZ20032313A3 (cs) 2004-08-18
HK1060516A1 (en) 2004-08-13
NO20033798L (no) 2003-09-26
TWI312679B (en) 2009-08-01
MY138156A (en) 2009-04-30
US20020165273A1 (en) 2002-11-07
IL157591A0 (en) 2004-03-28
CA2439295A1 (fr) 2002-09-06
BR0207645A (pt) 2004-12-28
RS67403A (sr) 2006-12-15
RU2300373C2 (ru) 2007-06-10
PL364680A1 (en) 2004-12-13
ATE361745T1 (de) 2007-06-15
CY1106753T1 (el) 2012-05-23
ES2284845T3 (es) 2007-11-16
KR100910928B1 (ko) 2009-08-06
RU2003128982A (ru) 2005-03-10
HUP0303264A2 (hu) 2004-01-28
KR20030076714A (ko) 2003-09-26
CN1235579C (zh) 2006-01-11
WO2002067925A1 (fr) 2002-09-06
PT1383489E (pt) 2007-06-21
US20040171679A1 (en) 2004-09-02
EP1383489A1 (fr) 2004-01-28
EP1383489B1 (fr) 2007-05-09
DE60220043D1 (de) 2007-06-21
CZ301203B6 (cs) 2009-12-09
JP2004523555A (ja) 2004-08-05
US20090005442A1 (en) 2009-01-01
CN1503667A (zh) 2004-06-09
CA2439295C (fr) 2010-05-25
MXPA03007718A (es) 2004-11-12
DE60220043T2 (de) 2008-01-10
HUP0303264A3 (en) 2012-07-30

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