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DK1370554T3 - 3-(4-Amidopyrrol-2-ylmethyliden)-2-indolinon-derivater som proteinkinaseinhibitorer - Google Patents

3-(4-Amidopyrrol-2-ylmethyliden)-2-indolinon-derivater som proteinkinaseinhibitorer

Info

Publication number
DK1370554T3
DK1370554T3 DK02714897T DK02714897T DK1370554T3 DK 1370554 T3 DK1370554 T3 DK 1370554T3 DK 02714897 T DK02714897 T DK 02714897T DK 02714897 T DK02714897 T DK 02714897T DK 1370554 T3 DK1370554 T3 DK 1370554T3
Authority
DK
Denmark
Prior art keywords
amidopyrrol
ylmethylidene
protein kinase
kinase inhibitors
indolinone derivatives
Prior art date
Application number
DK02714897T
Other languages
English (en)
Inventor
Congxin Liang
Li Sun
Peng Cho Tang
Chung Chen Wei
Tomas Vojkovsky
Huiping Guan
Michael A Mauragis
Qingwu Jin
Paul Matthew Herrinton
Original Assignee
Pharmacia & Upjohn Co Llc
Sugen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia & Upjohn Co Llc, Sugen Inc filed Critical Pharmacia & Upjohn Co Llc
Application granted granted Critical
Publication of DK1370554T3 publication Critical patent/DK1370554T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Obesity (AREA)
  • Dermatology (AREA)
  • Endocrinology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK02714897T 2001-02-15 2002-02-15 3-(4-Amidopyrrol-2-ylmethyliden)-2-indolinon-derivater som proteinkinaseinhibitorer DK1370554T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26868301P 2001-02-15 2001-02-15
US31236101P 2001-08-15 2001-08-15

Publications (1)

Publication Number Publication Date
DK1370554T3 true DK1370554T3 (da) 2006-02-06

Family

ID=26953263

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02714897T DK1370554T3 (da) 2001-02-15 2002-02-15 3-(4-Amidopyrrol-2-ylmethyliden)-2-indolinon-derivater som proteinkinaseinhibitorer

Country Status (40)

Country Link
US (4) US6653308B2 (da)
EP (1) EP1370554B1 (da)
JP (1) JP3677501B2 (da)
KR (1) KR100884858B1 (da)
CN (1) CN100338059C (da)
AP (1) AP1718A (da)
AR (1) AR042586A1 (da)
AT (1) ATE307128T1 (da)
AU (1) AU2002247133B2 (da)
BG (1) BG108098A (da)
BR (1) BR0207494A (da)
CA (1) CA2438314C (da)
CR (1) CR7056A (da)
CZ (1) CZ20032414A3 (da)
DE (1) DE60206736T2 (da)
DK (1) DK1370554T3 (da)
EA (1) EA007186B1 (da)
EE (1) EE200300385A (da)
ES (1) ES2251580T3 (da)
GE (1) GEP20053600B (da)
HR (1) HRP20030657B1 (da)
HU (1) HUP0303146A3 (da)
IL (2) IL157418A0 (da)
IS (1) IS2411B (da)
MA (1) MA26997A1 (da)
MX (1) MXPA03007367A (da)
MY (1) MY126235A (da)
NO (1) NO326604B1 (da)
NZ (1) NZ527572A (da)
OA (1) OA12834A (da)
PE (1) PE20021006A1 (da)
PL (1) PL364176A1 (da)
RS (1) RS51026B (da)
SI (1) SI1370554T1 (da)
SK (1) SK11332003A3 (da)
TN (1) TNSN03055A1 (da)
TW (1) TWI324155B (da)
UA (1) UA75635C2 (da)
WO (1) WO2002066463A1 (da)
ZA (2) ZA200306335B (da)

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