DK1370552T3 - Rho-kinase-inhibitorer - Google Patents
Rho-kinase-inhibitorerInfo
- Publication number
- DK1370552T3 DK1370552T3 DK02713884T DK02713884T DK1370552T3 DK 1370552 T3 DK1370552 T3 DK 1370552T3 DK 02713884 T DK02713884 T DK 02713884T DK 02713884 T DK02713884 T DK 02713884T DK 1370552 T3 DK1370552 T3 DK 1370552T3
- Authority
- DK
- Denmark
- Prior art keywords
- kinase inhibitors
- rho kinase
- rho
- inhibitors
- kinase
- Prior art date
Links
- 239000003590 rho kinase inhibitor Substances 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pulmonology (AREA)
- Biomedical Technology (AREA)
- Physical Education & Sports Medicine (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Ophthalmology & Optometry (AREA)
- Hematology (AREA)
- Rheumatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Vascular Medicine (AREA)
- Gynecology & Obstetrics (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US27797401P | 2001-03-23 | 2001-03-23 | |
| US31533801P | 2001-08-29 | 2001-08-29 | |
| PCT/US2002/008660 WO2002076977A2 (fr) | 2001-03-23 | 2002-03-22 | Inhibiteurs de rho-kinase |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1370552T3 true DK1370552T3 (da) | 2007-05-07 |
Family
ID=26958818
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK02713884T DK1370552T3 (da) | 2001-03-23 | 2002-03-22 | Rho-kinase-inhibitorer |
Country Status (18)
| Country | Link |
|---|---|
| US (3) | US20030087919A1 (fr) |
| EP (1) | EP1370552B1 (fr) |
| JP (1) | JP4320705B2 (fr) |
| AR (1) | AR035792A1 (fr) |
| AT (1) | ATE353889T1 (fr) |
| AU (1) | AU2002245709A1 (fr) |
| CA (1) | CA2441501C (fr) |
| CY (1) | CY1108041T1 (fr) |
| DE (1) | DE60218138T2 (fr) |
| DK (1) | DK1370552T3 (fr) |
| ES (1) | ES2280517T3 (fr) |
| MX (1) | MXPA03008659A (fr) |
| MY (1) | MY142915A (fr) |
| PE (1) | PE20020958A1 (fr) |
| PT (1) | PT1370552E (fr) |
| TW (1) | TWI336328B (fr) |
| UY (1) | UY27225A1 (fr) |
| WO (1) | WO2002076977A2 (fr) |
Families Citing this family (86)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8124630B2 (en) | 1999-01-13 | 2012-02-28 | Bayer Healthcare Llc | ω-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors |
| ATE538794T1 (de) | 1999-01-13 | 2012-01-15 | Bayer Healthcare Llc | Gamma carboxyarylsubstituierte diphenylharnstoffverbindungen als p38 kinasehemmer |
| MXPA04007832A (es) | 2002-02-11 | 2005-09-08 | Bayer Pharmaceuticals Corp | Aril-ureas con actividad inhibitoria de angiogenesis. |
| US7645878B2 (en) | 2002-03-22 | 2010-01-12 | Bayer Healthcare Llc | Process for preparing quinazoline Rho-kinase inhibitors and intermediates thereof |
| ES2382733T3 (es) | 2002-08-29 | 2012-06-13 | Santen Pharmaceutical Co., Ltd. | Remedio para el glaucoma que comprende un inhibidor de la Rho quinasa y prostaglandinas |
| GB0307333D0 (en) * | 2003-03-29 | 2003-05-07 | Astrazeneca Ab | Therapeutic agent |
| ES2370245T3 (es) * | 2003-04-18 | 2011-12-13 | Senju Pharmaceutical Co., Ltd. | 2-cloro-6,7-dimetoxi-n-[5-(1)h-indazolil]quinazolina-4-amina, dihidrocloruro de n-(1-bencil-4-piperidinil)-1h-indazol-5-amina, ácido 4-[2-(2,3,4,5,6-pentafluorofenil)acriloil]cinámico e hidrocloruro de fasudilo para uso en la recuperación de la percepción corneal. |
| EP1636585B2 (fr) | 2003-05-20 | 2012-06-13 | Bayer HealthCare LLC | Diaryl-urees presentant une activite d'inhibition des kinases |
| HRP20060073B1 (hr) | 2003-07-23 | 2014-03-14 | Bayer Healthcare Llc | Fluoro supstituirana omega-karboksiaril difenil urea za lijeäśenje i prevenciju bolesti i stanja |
| WO2005035506A1 (fr) | 2003-10-15 | 2005-04-21 | Ube Industries, Ltd. | Nouveau derive d'indazole |
| CN104688697A (zh) | 2005-03-07 | 2015-06-10 | 拜尔健康护理有限责任公司 | 用于治疗癌症的包含ω-羧芳基取代的二苯基脲的药物组合物 |
| CR9465A (es) * | 2005-03-25 | 2008-06-19 | Surface Logix Inc | Compuestos mejorados farmacocineticamente |
| EP1932841B1 (fr) | 2005-08-30 | 2014-01-01 | Asahi Kasei Pharma Corporation | Composé sulfonamide |
| CA2653424A1 (fr) | 2006-06-08 | 2007-12-13 | Ube Industries, Ltd. | Nouveau derive d'indazole ayant une structure cyclique spiro dans une chaine laterale |
| CA2700988A1 (fr) * | 2006-09-27 | 2008-05-08 | Surface Logix, Inc. | Inhibiteurs de la rho kinase |
| RS53588B1 (sr) | 2006-12-08 | 2015-02-27 | Irm Llc | Jedinjenja i kompozicije kao inhibitori protein kinaza |
| BRPI0720264B1 (pt) * | 2006-12-08 | 2022-03-03 | Novartis Ag | Compostos e composições como inibidores de proteína cinase |
| US8415372B2 (en) | 2007-02-27 | 2013-04-09 | Asahi Kasei Pharma Corporation | Sulfonamide compound |
| CN101622243B (zh) | 2007-02-28 | 2013-12-04 | 旭化成制药株式会社 | 磺酰胺衍生物 |
| AU2008272396B2 (en) | 2007-07-02 | 2011-09-08 | Asahi Kasei Pharma Corporation | Sulfonamide Compound and Crystal Thereof |
| KR20100080514A (ko) | 2007-08-29 | 2010-07-08 | 센주 세이야꾸 가부시키가이샤 | 각막 내피 세포 접착 촉진제 |
| US9109245B2 (en) | 2009-04-22 | 2015-08-18 | Viacyte, Inc. | Cell compositions derived from dedifferentiated reprogrammed cells |
| WO2010124142A2 (fr) | 2009-04-22 | 2010-10-28 | Cythera, Inc. | Compositions cellulaires issues de cellules reprogrammées dédifférenciées |
| ES2638464T3 (es) | 2009-10-16 | 2017-10-20 | The Scripps Research Institute | Inducción de células pluripotentes |
| CA2777552C (fr) | 2009-10-19 | 2019-05-21 | Cellular Dynamics International, Inc. | Production de cardiomyocytes |
| US8691574B2 (en) | 2010-06-15 | 2014-04-08 | Cellular Dynamics International, Inc. | Generation of induced pluripotent stem cells from small volumes of peripheral blood |
| CN106893692B (zh) | 2010-12-22 | 2021-11-26 | 菲特治疗公司 | 用于单细胞分选与增强ipsc重新编程的细胞培养平台 |
| CN103857288B (zh) | 2011-03-04 | 2016-09-21 | 葛兰素史密斯克莱知识产权发展有限公司 | 作为激酶抑制剂的氨基-喹啉 |
| US9487752B2 (en) | 2011-03-30 | 2016-11-08 | Cellular Dynamics International, Inc. | Priming of pluripotent stem cells for neural differentiation |
| JP2014520551A (ja) | 2011-07-11 | 2014-08-25 | セルラー ダイナミクス インターナショナル， インコーポレイテッド | 細胞のリプログラミング方法およびゲノムの改変方法 |
| TWI547494B (zh) | 2011-08-18 | 2016-09-01 | 葛蘭素史克智慧財產發展有限公司 | 作為激酶抑制劑之胺基喹唑啉類 |
| CA2858173C (fr) | 2011-12-06 | 2023-09-26 | Advanced Cell Technology, Inc. | Procede de differenciation dirigee produisant des cellules endotheliales corneennes, leurs compositions et leurs utilisations |
| WO2013100208A1 (fr) | 2011-12-28 | 2013-07-04 | 京都府公立大学法人 | Normalisation d'une culture de cellules endothéliales de la cornée |
| EP2628482A1 (fr) | 2012-02-17 | 2013-08-21 | Academisch Medisch Centrum | Inhibiteurs du rho kinase pour l'utilisation dans le traitement du neuroblastome |
| EP2826855B1 (fr) | 2012-03-15 | 2018-08-29 | iHeart Japan Corporation | Feuillet de cellules myocardiques |
| US9334475B2 (en) | 2012-04-06 | 2016-05-10 | Kyoto University | Method for inducing erythropoietin-producing cell |
| AR092529A1 (es) | 2012-09-13 | 2015-04-22 | Glaxosmithkline Llc | Compuesto de aminoquinazolina, composicion farmaceutica que lo comprende y uso de dicho compuesto para la preparacion de un medicamento |
| EP2958911B1 (fr) | 2013-02-21 | 2017-10-18 | GlaxoSmithKline Intellectual Property Development Limited | Quinazolines en tant qu'inhibiteurs de kinase |
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| EP3020803B1 (fr) | 2013-06-11 | 2020-03-11 | Kyoto University | Procédé de production de cellules précurseurs rénales |
| EP3029140A4 (fr) | 2013-07-30 | 2017-06-28 | Kyoto Prefectural Public University Corporation | Marqueur de cellules endothéliales cornéennes |
| US9796962B2 (en) | 2013-08-07 | 2017-10-24 | Kyoto University | Method for generating pancreatic hormone-producing cells |
| SG11201601720RA (en) | 2013-09-05 | 2016-04-28 | Univ Kyoto | New method for inducing dopamine-producing neural precursor cells |
| JPWO2015064768A1 (ja) | 2013-10-31 | 2017-03-09 | 京都府公立大学法人 | 角膜内皮の小胞体細胞死関連疾患治療薬 |
| RU2704984C1 (ru) | 2013-11-27 | 2019-11-01 | Киото Прифекчурал Паблик Юниверсити Корпорэйшн | Применение ламинина в культуре клеток эндотелия роговицы |
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| WO2015178431A1 (fr) | 2014-05-21 | 2015-11-26 | 国立大学法人京都大学 | Procédé de production de cellules blastiques pancréatiques et agent de traitement d'une maladie du pancréas les contenant |
| WO2016104717A1 (fr) | 2014-12-26 | 2016-06-30 | 国立大学法人京都大学 | Procédé d'induction d'hépatocytes |
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| TWI812584B (zh) | 2015-10-30 | 2023-08-21 | 美國加利福尼亞大學董事會 | 從幹細胞產生t細胞之方法及使用該t細胞之免疫療法 |
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| RU2730864C1 (ru) | 2017-11-10 | 2020-08-26 | Редженесис Сайенс Ко., Лтд. | Способ производства культивируемых клеток и лекарственного препарата для лечения спинномозговых травм |
| JP7416700B2 (ja) | 2017-11-14 | 2024-01-17 | ザ スキーペンズ アイ リサーチ インスティチュート インコーポレイテッド | 増殖性硝子体網膜症および上皮間葉転換と関連付けられる状態の治療のためのｒｕｎｘ１阻害の方法 |
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| JP7336386B2 (ja) | 2017-12-28 | 2023-08-31 | 株式会社カネカ | 多能性幹細胞凝集抑制剤 |
| CN111527197A (zh) | 2017-12-28 | 2020-08-11 | 株式会社钟化 | 细胞聚集促进剂 |
| EP3757208A4 (fr) | 2018-02-19 | 2021-12-01 | Sumitomo Dainippon Pharma Co., Ltd. | Agrégat cellulaire, mélange d'agrégats cellulaires et sa méthode de préparation |
| US20210332329A1 (en) | 2018-07-23 | 2021-10-28 | Kyoto University | Novel renal progenitor cell marker and method for concentrating renal progenitor cells using same |
| WO2020047229A1 (fr) | 2018-08-29 | 2020-03-05 | University Of Massachusetts | Inhibition de protéines kinases pour traiter la maladie de friedreich |
| CN113056556A (zh) | 2018-08-31 | 2021-06-29 | 学校法人同志社 | 用于对眼细胞进行保存或培养的组合物以及方法 |
| CA3109705A1 (fr) | 2018-10-02 | 2020-04-09 | The Doshisha | Procede et recipient pour la conservation de cellules endotheliales corneennes |
| EP3900787A4 (fr) | 2018-12-21 | 2022-02-23 | Kyoto University | Tissu de type cartilage à lubricine localisée, procédé pour sa production et composition le comprenant pour le traitement de lésions du cartilage articulaire |
| WO2020193802A1 (fr) | 2019-03-28 | 2020-10-01 | Fundación De La Comunidad Valenciana Centro De Investigación Príncipe Felipe | Conjugués polymères et leurs utilisations |
| US20220169977A1 (en) | 2019-03-29 | 2022-06-02 | Kaneka Corporation | Cell population including pluripotent stem cells and production method thereof |
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| JP2024519218A (ja) | 2021-05-03 | 2024-05-09 | アステラス インスティテュート フォー リジェネレイティブ メディシン | 成熟角膜内皮細胞を作製する方法 |
| WO2022259721A1 (fr) | 2021-06-10 | 2022-12-15 | 味の素株式会社 | Procédé de production de cellules souches mésenchymateuses |
| JPWO2023017848A1 (fr) | 2021-08-11 | 2023-02-16 | ||
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-
2002
- 2002-03-22 UY UY27225A patent/UY27225A1/es unknown
- 2002-03-22 MY MYPI20021019A patent/MY142915A/en unknown
- 2002-03-22 WO PCT/US2002/008660 patent/WO2002076977A2/fr not_active Ceased
- 2002-03-22 DK DK02713884T patent/DK1370552T3/da active
- 2002-03-22 ES ES02713884T patent/ES2280517T3/es not_active Expired - Lifetime
- 2002-03-22 TW TW091105577A patent/TWI336328B/zh not_active IP Right Cessation
- 2002-03-22 EP EP02713884A patent/EP1370552B1/fr not_active Expired - Lifetime
- 2002-03-22 PT PT02713884T patent/PT1370552E/pt unknown
- 2002-03-22 AT AT02713884T patent/ATE353889T1/de active
- 2002-03-22 AR ARP020101070A patent/AR035792A1/es active IP Right Grant
- 2002-03-22 MX MXPA03008659A patent/MXPA03008659A/es active IP Right Grant
- 2002-03-22 PE PE2002000225A patent/PE20020958A1/es not_active Application Discontinuation
- 2002-03-22 JP JP2002576235A patent/JP4320705B2/ja not_active Expired - Fee Related
- 2002-03-22 US US10/103,565 patent/US20030087919A1/en not_active Abandoned
- 2002-03-22 DE DE60218138T patent/DE60218138T2/de not_active Expired - Lifetime
- 2002-03-22 AU AU2002245709A patent/AU2002245709A1/en not_active Abandoned
- 2002-03-22 CA CA2441501A patent/CA2441501C/fr not_active Expired - Fee Related
-
2006
- 2006-02-16 US US11/354,978 patent/US20060142314A1/en not_active Abandoned
-
2007
- 2007-04-19 CY CY20071100536T patent/CY1108041T1/el unknown
-
2010
- 2010-03-18 US US12/726,660 patent/US20100249159A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20100249159A1 (en) | 2010-09-30 |
| CA2441501C (fr) | 2010-09-14 |
| JP4320705B2 (ja) | 2009-08-26 |
| HK1061029A1 (en) | 2004-09-03 |
| WO2002076977A2 (fr) | 2002-10-03 |
| CA2441501A1 (fr) | 2002-10-03 |
| WO2002076977A3 (fr) | 2002-12-12 |
| ATE353889T1 (de) | 2007-03-15 |
| UY27225A1 (es) | 2002-10-31 |
| TWI336328B (en) | 2011-01-21 |
| PT1370552E (pt) | 2007-04-30 |
| US20030087919A1 (en) | 2003-05-08 |
| ES2280517T3 (es) | 2007-09-16 |
| AR035792A1 (es) | 2004-07-14 |
| US20060142314A1 (en) | 2006-06-29 |
| CY1108041T1 (el) | 2013-09-04 |
| EP1370552B1 (fr) | 2007-02-14 |
| EP1370552A2 (fr) | 2003-12-17 |
| DE60218138D1 (de) | 2007-03-29 |
| MY142915A (en) | 2011-01-31 |
| PE20020958A1 (es) | 2002-11-14 |
| DE60218138T2 (de) | 2007-09-20 |
| JP2004528314A (ja) | 2004-09-16 |
| AU2002245709A1 (en) | 2002-10-08 |
| MXPA03008659A (es) | 2005-04-08 |
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