DK1368021T3 - Carbamatforbindelser til anvendelse ved forebyggelse eller behandling af bipolær sygdom - Google Patents
Carbamatforbindelser til anvendelse ved forebyggelse eller behandling af bipolær sygdomInfo
- Publication number
- DK1368021T3 DK1368021T3 DK02707850T DK02707850T DK1368021T3 DK 1368021 T3 DK1368021 T3 DK 1368021T3 DK 02707850 T DK02707850 T DK 02707850T DK 02707850 T DK02707850 T DK 02707850T DK 1368021 T3 DK1368021 T3 DK 1368021T3
- Authority
- DK
- Denmark
- Prior art keywords
- sub
- bipolar disorder
- phenyl
- alkyl
- group
- Prior art date
Links
- 208000020925 Bipolar disease Diseases 0.000 title abstract 2
- 150000004657 carbamic acid derivatives Chemical class 0.000 title 1
- 230000002265 prevention Effects 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 3
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 abstract 1
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 229910052731 fluorine Inorganic materials 0.000 abstract 1
- 239000011737 fluorine Substances 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 150000002367 halogens Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910052740 iodine Inorganic materials 0.000 abstract 1
- 239000011630 iodine Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/325—Carbamic acids; Thiocarbamic acids; Anhydrides or salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Psychiatry (AREA)
- Emergency Medicine (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US27168001P | 2001-02-27 | 2001-02-27 | |
| PCT/US2002/005425 WO2002067924A1 (fr) | 2001-02-27 | 2002-02-21 | Composes de carbamate utiles pour prevenir ou traiter un trouble bipolaire |
| US10/081,606 US7122576B2 (en) | 2001-02-27 | 2002-02-21 | Carbamate compounds for use in preventing or treating bipolar disorder |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1368021T3 true DK1368021T3 (da) | 2008-02-11 |
Family
ID=26765743
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK02707850T DK1368021T3 (da) | 2001-02-27 | 2002-02-21 | Carbamatforbindelser til anvendelse ved forebyggelse eller behandling af bipolær sygdom |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US7122576B2 (fr) |
| EP (1) | EP1368021B1 (fr) |
| JP (1) | JP4276839B2 (fr) |
| KR (1) | KR20030074849A (fr) |
| CN (1) | CN1250214C (fr) |
| AT (1) | ATE378046T1 (fr) |
| AU (1) | AU2002242226B2 (fr) |
| BR (1) | BR0207832A (fr) |
| CA (1) | CA2439292A1 (fr) |
| CY (1) | CY1107199T1 (fr) |
| CZ (1) | CZ296641B6 (fr) |
| DE (1) | DE60223506T2 (fr) |
| DK (1) | DK1368021T3 (fr) |
| ES (1) | ES2295320T3 (fr) |
| HU (1) | HUP0303261A3 (fr) |
| IL (2) | IL157589A0 (fr) |
| MX (1) | MXPA03007716A (fr) |
| MY (1) | MY133370A (fr) |
| NO (1) | NO20033799L (fr) |
| NZ (1) | NZ527989A (fr) |
| PL (1) | PL364640A1 (fr) |
| PT (1) | PT1368021E (fr) |
| RS (1) | RS50680B (fr) |
| RU (1) | RU2286147C2 (fr) |
| WO (1) | WO2002067924A1 (fr) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006033947A2 (fr) * | 2004-09-16 | 2006-03-30 | Janssen Pharmaceutica, N.V. | Techniques de traitement de l'epileptogenese et de l'epilepsie |
| FR2884714B1 (fr) * | 2005-04-20 | 2011-05-06 | Servier Lab | Utilisation de l'agomelatine pour l'obtention de medicaments destines au traitement des troubles bipolaires |
| US20070021501A1 (en) * | 2005-07-12 | 2007-01-25 | Twyman Roy E | Methods of treating epileptogenesis |
| BRPI0520451A2 (pt) * | 2005-07-26 | 2009-05-12 | Janssen Pharmaceutica Nv | métodos para tratamento de distúrbios associados a substáncias quìmicas |
| CN101568362A (zh) * | 2006-10-30 | 2009-10-28 | 詹森药业有限公司 | 治疗抑郁症的方法 |
| HUP0700353A2 (en) * | 2007-05-18 | 2008-12-29 | Richter Gedeon Nyrt | Metabolites of (thio)carbamoyl-cyclohexane derivatives |
| HUP0700370A2 (en) * | 2007-05-24 | 2009-04-28 | Richter Gedeon Nyrt | Use of (thio)-carbamoyl-cyclohexane derivatives in the manufacture of a medicament for the treatment of acute mania |
| US7875610B2 (en) * | 2007-12-03 | 2011-01-25 | Richter Gedeon Nyrt. | Pyrimidinyl-piperazines useful as D3/D2 receptor ligands |
| CN102014909B (zh) * | 2008-02-21 | 2013-03-13 | 田边三菱制药株式会社 | 口服用固体制剂 |
| NZ590852A (en) | 2008-07-16 | 2013-03-28 | Richter Gedeon Nyrt | Pharmaceutical formulations containing dopamine receptor ligands trans-1{ 4-[2-[4-(2,3-dichlorophenyl)-piperizin-1-yl]-ethyl]-cyclohexyl} -3,3-dimethyl-urea also known as cariprazine |
| HU230067B1 (hu) | 2008-12-17 | 2015-06-29 | Richter Gedeon Nyrt | Új piperazin só és eljárás előállítására |
| HUP0800765A2 (en) | 2008-12-18 | 2010-11-29 | Richter Gedeon Nyrt | A new process for the preparation of piperazine derivatives and their hydrochloric salts |
| HUP0800766A2 (en) | 2008-12-18 | 2010-11-29 | Richter Gedeon Vegyeszet | Process for the preparation of piperazine derivatives |
| US11274087B2 (en) | 2016-07-08 | 2022-03-15 | Richter Gedeon Nyrt. | Industrial process for the preparation of cariprazine |
| CN110290788A (zh) * | 2016-12-14 | 2019-09-27 | 爱思开生物制药株式会社 | 氨基甲酸酯化合物用于预防、缓解或治疗双相障碍的用途 |
| US11547707B2 (en) | 2019-04-10 | 2023-01-10 | Richter Gedeon Nyrt. | Carbamoyl cyclohexane derivatives for treating autism spectrum disorder |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3313692A (en) | 1958-04-21 | 1967-04-11 | Armour Pharma | Method of inducing calming and muscle relaxation with carbamates |
| US3278380A (en) | 1962-02-06 | 1966-10-11 | Armour Pharma | Methods of calming employing diphenyl hydroxy carbamate compounds |
| US3265728A (en) | 1962-07-18 | 1966-08-09 | Armour Pharma | Substituted phenethyl carbamates |
| US5698588A (en) * | 1996-01-16 | 1997-12-16 | Yukong Limited | Halogen substituted carbamate compounds from 2-phenyl-1,2-ethanediol |
-
2002
- 2002-02-21 EP EP02707850A patent/EP1368021B1/fr not_active Expired - Lifetime
- 2002-02-21 IL IL15758902A patent/IL157589A0/xx unknown
- 2002-02-21 HU HU0303261A patent/HUP0303261A3/hu unknown
- 2002-02-21 BR BR0207832-5A patent/BR0207832A/pt not_active Application Discontinuation
- 2002-02-21 JP JP2002567291A patent/JP4276839B2/ja not_active Expired - Fee Related
- 2002-02-21 ES ES02707850T patent/ES2295320T3/es not_active Expired - Lifetime
- 2002-02-21 DE DE60223506T patent/DE60223506T2/de not_active Expired - Lifetime
- 2002-02-21 CN CNB02808716XA patent/CN1250214C/zh not_active Expired - Fee Related
- 2002-02-21 MX MXPA03007716A patent/MXPA03007716A/es active IP Right Grant
- 2002-02-21 DK DK02707850T patent/DK1368021T3/da active
- 2002-02-21 PT PT02707850T patent/PT1368021E/pt unknown
- 2002-02-21 US US10/081,606 patent/US7122576B2/en not_active Expired - Fee Related
- 2002-02-21 AT AT02707850T patent/ATE378046T1/de active
- 2002-02-21 KR KR10-2003-7011290A patent/KR20030074849A/ko not_active Ceased
- 2002-02-21 PL PL02364640A patent/PL364640A1/xx not_active Application Discontinuation
- 2002-02-21 AU AU2002242226A patent/AU2002242226B2/en not_active Ceased
- 2002-02-21 NZ NZ527989A patent/NZ527989A/en not_active IP Right Cessation
- 2002-02-21 RS YUP-680/03A patent/RS50680B/sr unknown
- 2002-02-21 CZ CZ20032312A patent/CZ296641B6/cs not_active IP Right Cessation
- 2002-02-21 CA CA002439292A patent/CA2439292A1/fr not_active Abandoned
- 2002-02-21 RU RU2003128996/14A patent/RU2286147C2/ru not_active IP Right Cessation
- 2002-02-21 WO PCT/US2002/005425 patent/WO2002067924A1/fr not_active Ceased
- 2002-02-27 MY MYPI20020694A patent/MY133370A/en unknown
-
2003
- 2003-08-26 IL IL157589A patent/IL157589A/en active IP Right Grant
- 2003-08-26 NO NO20033799A patent/NO20033799L/no not_active Application Discontinuation
-
2008
- 2008-02-14 CY CY20081100183T patent/CY1107199T1/el unknown
Also Published As
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