DK1341928T3 - Fremgangsmåder og kit til påvisning af proteinkinaser - Google Patents
Fremgangsmåder og kit til påvisning af proteinkinaserInfo
- Publication number
- DK1341928T3 DK1341928T3 DK01270619T DK01270619T DK1341928T3 DK 1341928 T3 DK1341928 T3 DK 1341928T3 DK 01270619 T DK01270619 T DK 01270619T DK 01270619 T DK01270619 T DK 01270619T DK 1341928 T3 DK1341928 T3 DK 1341928T3
- Authority
- DK
- Denmark
- Prior art keywords
- atp
- tested
- kits
- methods
- protein kinase
- Prior art date
Links
- 102000001253 Protein Kinase Human genes 0.000 title abstract 5
- 108060006633 protein kinase Proteins 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 2
- 108091000080 Phosphotransferase Proteins 0.000 abstract 1
- 230000029918 bioluminescence Effects 0.000 abstract 1
- 238000005415 bioluminescence Methods 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 102000020233 phosphotransferase Human genes 0.000 abstract 1
- 239000011541 reaction mixture Substances 0.000 abstract 1
- 239000000758 substrate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
- C12Q1/485—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase involving kinase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0030727.2A GB0030727D0 (en) | 2000-12-15 | 2000-12-15 | Methods and kits for detecting kinase activity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1341928T3 true DK1341928T3 (da) | 2006-03-27 |
Family
ID=9905234
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK01270619T DK1341928T3 (da) | 2000-12-15 | 2001-12-13 | Fremgangsmåder og kit til påvisning af proteinkinaser |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US6599711B2 (fr) |
| EP (1) | EP1341928B1 (fr) |
| JP (1) | JP3854927B2 (fr) |
| AT (1) | ATE310101T1 (fr) |
| AU (1) | AU2002222193A1 (fr) |
| CA (1) | CA2431274C (fr) |
| CH (1) | CH694096A5 (fr) |
| DE (2) | DE60115090T2 (fr) |
| DK (1) | DK1341928T3 (fr) |
| ES (1) | ES2256165T3 (fr) |
| GB (2) | GB0030727D0 (fr) |
| WO (1) | WO2002048390A2 (fr) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0030727D0 (en) * | 2000-12-15 | 2001-01-31 | Lumitech Uk Ltd | Methods and kits for detecting kinase activity |
| JP5155515B2 (ja) * | 2002-09-06 | 2013-03-06 | プロメガ コーポレイション | トランスフェラーゼ酵素活性を検出する方法 |
| US7799526B2 (en) | 2002-11-21 | 2010-09-21 | The University Of North Carolina At Chapel Hill | Phosphoprotein detection reagent and methods of making and using the same |
| WO2004059294A2 (fr) | 2002-12-23 | 2004-07-15 | Promega Corporation | Amelioration portant sur des analyses a base de luciferase |
| EP1592813B1 (fr) * | 2003-01-30 | 2012-12-26 | BellBrook Labs, LLC | Procede relatif a des essais de reactions a transfert de groupe |
| US8088897B2 (en) * | 2003-01-30 | 2012-01-03 | BellBrook Labs, Inc. | Assay method for group transfer reactions |
| US7378505B2 (en) * | 2003-01-30 | 2008-05-27 | Bellbrook Labs Llc | Assay method for group transfer reactions |
| US7355010B2 (en) * | 2003-01-30 | 2008-04-08 | Bellbrook Labs, Llc | Assay method for group transfer reactions |
| US7619059B2 (en) | 2003-07-29 | 2009-11-17 | Life Technologies Corporation | Bimolecular optical probes |
| CA2445420A1 (fr) | 2003-07-29 | 2005-01-29 | Invitrogen Corporation | Tests de kinase et de phosphatase |
| US7727752B2 (en) | 2003-07-29 | 2010-06-01 | Life Technologies Corporation | Kinase and phosphatase assays |
| SI1803468T1 (sl) * | 2003-12-22 | 2011-12-30 | Novartis Ag | Sredstva za zdravljenje glavkomatozne retinopatije in optične nevropatije |
| TW200526224A (en) * | 2003-12-22 | 2005-08-16 | Alcon Inc | Short form c-Maf transcription factor antagonists for treatment of glaucoma |
| WO2005063249A1 (fr) * | 2003-12-22 | 2005-07-14 | Alcon, Inc. | Agents pour le traitement de la retinopathie diabetique et la formation de corps colloides dans la degeneration maculaire |
| JP2007518094A (ja) | 2004-01-16 | 2007-07-05 | エムディエス・ファーマ・サーヴィシーズ | 蛍光に基づくadpの検出システム |
| JP4974528B2 (ja) * | 2004-02-09 | 2012-07-11 | 扶桑薬品工業株式会社 | 核酸検出方法およびその利用 |
| US20050222127A1 (en) * | 2004-03-30 | 2005-10-06 | Alcon, Inc. | Use of Rho kinase inhibitors in the treatment of hearing loss, tinnitus and improving body balance |
| US20080096238A1 (en) * | 2004-03-30 | 2008-04-24 | Alcon, Inc. | High throughput assay for human rho kinase activity with enhanced signal-to-noise ratio |
| US20060115870A1 (en) * | 2004-03-30 | 2006-06-01 | Alcon, Inc. | High throughput assay for human Rho kinase activity |
| WO2006085972A2 (fr) * | 2004-07-02 | 2006-08-17 | Promega Corporation | Systeme de detection et d'extraction d'atp microbienne |
| JP4664375B2 (ja) * | 2004-11-18 | 2011-04-06 | サラダックス バイオメディカル インコーポレイテッド | メシル酸イマチニブの酵素測定 |
| US7338775B1 (en) | 2005-02-09 | 2008-03-04 | Myriad Genetics, Inc. | Enzyme assay and use thereof |
| US20060234323A1 (en) * | 2005-04-18 | 2006-10-19 | Cali James J | Luminescent ATP detection with extended linearity |
| US7348159B2 (en) * | 2005-04-20 | 2008-03-25 | Boehringer Ingelheim International Gmbh | Methods for determining phosphoryltransferase activity using adenosine 5'-triphosphate (ATP)-gamma-S |
| DE112006003044T5 (de) * | 2005-10-21 | 2008-10-23 | Deere & Company, Moline | Vielseitiges Robotersteuermodul |
| US8093014B2 (en) | 2006-02-13 | 2012-01-10 | Dvs Sciences Inc. | Kit for detecting and measuring element tagged kinases and phosphatases by inductively coupled plasma mass spectrometry |
| EP2021793B1 (fr) | 2006-05-27 | 2017-04-26 | Fluidigm Canada Inc. | Elements de marquage a squelette polymerique |
| KR100746961B1 (ko) | 2006-07-31 | 2007-08-07 | 한국과학기술연구원 | 단백질 키나아제 a 검출용 바이오 센서, 및 이를 포함하는키트 |
| US20080057531A1 (en) * | 2006-08-07 | 2008-03-06 | Oregon Health And Science University | Systems, kits, and methods for detecting cariogenic bacteria and assessing risk of dental caries |
| US7977043B2 (en) * | 2006-11-10 | 2011-07-12 | Boehringer Ingelheim International Gmbh | Assays useful in determining CD38 inhibition |
| DE102006059881A1 (de) * | 2006-12-19 | 2008-07-03 | Sanofi-Aventis | Ein Hochdurchsatzassay zur Identifizierung von Kinaseinhibitoren und Kinaseaktivatoren basierend auf der Messung der ATP-Hydrolyse |
| US8183007B2 (en) * | 2008-07-22 | 2012-05-22 | Promega Corporation | ADP detection based methods using adenylate cyclase and bioluminescence |
| US20140080161A1 (en) * | 2010-09-14 | 2014-03-20 | Research And Diagnostic Systems, Inc. | Phosphatase coupled kinase assay |
| GB201017721D0 (en) * | 2010-10-20 | 2010-12-01 | Queen Mary & Westfield College | Method |
| NL2013366B1 (en) | 2014-08-26 | 2016-09-23 | Stichting Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis | Adenylation enzyme inhibitors. |
| WO2016057084A1 (fr) | 2014-10-08 | 2016-04-14 | Promega Corporation | Dosage de détection de succinate bioluminescente |
| EP3321677B1 (fr) * | 2015-07-06 | 2021-03-24 | FUJIFILM Corporation | Kit de test sanguin et procédé d'analyse l'utilisant |
| KR101788096B1 (ko) * | 2016-04-12 | 2017-10-19 | 재단법인 한국파스퇴르연구소 | 티아민 모노포스페이트 키나아제를 이용한 항균물질의 스크리닝 키트 및 스크리닝 방법 |
| JP7414029B2 (ja) * | 2021-02-26 | 2024-01-16 | 横河電機株式会社 | 測定方法及び測定システム |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE428379B (sv) * | 1978-05-31 | 1983-06-27 | Lkb Produkter Ab | Bioluminiscens bestemning av atp och reagens herfor |
| DE2828658C3 (de) | 1978-06-29 | 1981-10-22 | Lkb-Produkter Ab, Stockholm | Verfahren zur photometrischen Bestimmung der Untereinheit B der Creatinkinase und Reagens hierfür |
| DE2908054A1 (de) | 1979-03-02 | 1980-09-11 | Boehringer Mannheim Gmbh | Verfahren und reagenz zur bestimmung der creatinkinase |
| SE7905852L (sv) * | 1979-07-04 | 1981-01-05 | Lkb Produkter Ab | Forfarande for bestemning av kreatinkinas |
| GB2055200B (en) * | 1979-07-24 | 1984-05-02 | Kolehmainen S | Luminescent assays with enzymatic cycling enhancement of the sensitivity of bioluminescent and chemi |
| DE8533854U1 (de) * | 1985-12-02 | 1986-02-27 | Lewandoske, Herbert, 8620 Lichtenfels | Sitzmöbel, insbesondere Sofa (und Sessel) mit abklappbaren Armlehnen |
| US5583024A (en) | 1985-12-02 | 1996-12-10 | The Regents Of The University Of California | Recombinant expression of Coleoptera luciferase |
| US4968613A (en) | 1987-07-29 | 1990-11-06 | Kikkoman Corporation | Luciferase gene and novel recombinant DNA as well as a method of producing luciferase |
| US5219737A (en) | 1990-03-27 | 1993-06-15 | Kikkoman Corporation | Mutant luciferase of a firefly, mutant luciferase genes, recombinant dnas containing the genes and a method of producing mutant luciferase |
| US5374534A (en) | 1990-07-19 | 1994-12-20 | Charm Sciences, Inc. | Method of preparing D-luciferin derivatives |
| US5648232A (en) | 1993-01-21 | 1997-07-15 | The Secretary Of State For Defence In Her Britannic Majesty's Government Of The United Kingdom Of Great Britain And Northern Ireland | Microbiological best method and reagents |
| GB9301118D0 (en) | 1993-01-21 | 1993-03-10 | Secr Defence | Enzyme linked assays |
| EP1978092A1 (fr) | 1994-01-03 | 2008-10-08 | Promega Corporation | Luciférases mutantes |
| DK0804587T3 (da) | 1995-01-20 | 2004-10-11 | Secr Defence | Mutantluciferaser |
| JP3409962B2 (ja) * | 1996-03-04 | 2003-05-26 | キッコーマン株式会社 | 生物発光試薬及びその試薬を用いたアデノシンリン酸エステルの定量法並びにその試薬を用いたatp変換反応系に関与する物質の定量法 |
| US5759795A (en) * | 1996-03-08 | 1998-06-02 | Schering Corporation | Assay for determining inhibitors of ATPase |
| US5925558A (en) * | 1996-07-16 | 1999-07-20 | The Regents Of The University Of California | Assays for protein kinases using fluorescent protein substrates |
| US5759787A (en) * | 1996-08-26 | 1998-06-02 | Tularik Inc. | Kinase assay |
| GB9626932D0 (en) | 1996-12-24 | 1997-02-12 | Lumitech Limited | Assay methods and kits therefor |
| GB9707486D0 (en) | 1997-04-11 | 1997-05-28 | Secr Defence | Enzyme assays |
| US6310060B1 (en) * | 1998-06-24 | 2001-10-30 | Warner-Lambert Company | 2-(4-bromo or 4-iodo phenylamino) benzoic acid derivatives and their use as MEK inhibitors |
| US6074859A (en) | 1997-07-08 | 2000-06-13 | Kikkoman Corporation | Mutant-type bioluminescent protein, and process for producing the mutant-type bioluminescent protein |
| DE69841292D1 (de) | 1997-07-08 | 2009-12-31 | Kikkoman Corp | Mutiertes Biolumineszenz-Protein und Verfahren zu dessen Herstellung |
| US6861230B1 (en) | 1998-01-21 | 2005-03-01 | The Secretary Of State For Defence In Her Britannic Majesty's Government Of The United Kingdom Of Great Britain And Northern Ireland | Antibiotic sensitivity testing |
| GB9803156D0 (en) | 1998-02-13 | 1998-04-08 | Celsis Int Plc | Assay |
| NL1010224C2 (nl) | 1998-09-30 | 2000-03-31 | Packard Biosciene B V | Werkwijze voor het detecteren van ATP. |
| DE19901427C1 (de) * | 1999-01-18 | 2000-08-10 | Walter Knoll Gmbh & Co Kg Sitz | Sitzmöbel |
| GB9911095D0 (en) | 1999-05-13 | 1999-07-14 | Secr Defence | Microbiological test method and reagents |
| GB0030727D0 (en) | 2000-12-15 | 2001-01-31 | Lumitech Uk Ltd | Methods and kits for detecting kinase activity |
-
2000
- 2000-12-15 GB GBGB0030727.2A patent/GB0030727D0/en not_active Ceased
-
2001
- 2001-12-13 DE DE60115090T patent/DE60115090T2/de not_active Expired - Lifetime
- 2001-12-13 GB GB0129889A patent/GB2375171B/en not_active Expired - Lifetime
- 2001-12-13 ES ES01270619T patent/ES2256165T3/es not_active Expired - Lifetime
- 2001-12-13 DE DE10196608T patent/DE10196608T1/de not_active Ceased
- 2001-12-13 AT AT01270619T patent/ATE310101T1/de active
- 2001-12-13 WO PCT/GB2001/005506 patent/WO2002048390A2/fr not_active Ceased
- 2001-12-13 AU AU2002222193A patent/AU2002222193A1/en not_active Abandoned
- 2001-12-13 CA CA2431274A patent/CA2431274C/fr not_active Expired - Lifetime
- 2001-12-13 EP EP01270619A patent/EP1341928B1/fr not_active Expired - Lifetime
- 2001-12-13 JP JP2002550104A patent/JP3854927B2/ja not_active Expired - Fee Related
- 2001-12-13 CH CH00834/03A patent/CH694096A5/de not_active IP Right Cessation
- 2001-12-13 DK DK01270619T patent/DK1341928T3/da active
- 2001-12-14 US US10/014,816 patent/US6599711B2/en not_active Expired - Lifetime
-
2003
- 2003-05-01 US US10/426,973 patent/US6911319B2/en not_active Expired - Lifetime
-
2004
- 2004-07-16 US US10/892,285 patent/US20040253658A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| DE60115090T2 (de) | 2006-07-13 |
| WO2002048390A2 (fr) | 2002-06-20 |
| EP1341928A2 (fr) | 2003-09-10 |
| DE60115090D1 (de) | 2005-12-22 |
| JP3854927B2 (ja) | 2006-12-06 |
| ES2256165T3 (es) | 2006-07-16 |
| CA2431274C (fr) | 2011-05-17 |
| US20020172991A1 (en) | 2002-11-21 |
| DE10196608T1 (de) | 2003-07-31 |
| US6599711B2 (en) | 2003-07-29 |
| CH694096A5 (de) | 2004-07-15 |
| US6911319B2 (en) | 2005-06-28 |
| EP1341928B1 (fr) | 2005-11-16 |
| WO2002048390A3 (fr) | 2003-06-26 |
| CA2431274A1 (fr) | 2002-06-20 |
| GB0030727D0 (en) | 2001-01-31 |
| US20040077030A1 (en) | 2004-04-22 |
| JP2004518422A (ja) | 2004-06-24 |
| GB2375171B (en) | 2003-03-12 |
| ATE310101T1 (de) | 2005-12-15 |
| AU2002222193A1 (en) | 2002-06-24 |
| GB2375171A (en) | 2002-11-06 |
| US20040253658A1 (en) | 2004-12-16 |
| GB0129889D0 (en) | 2002-02-06 |
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