DK1292607T3 - Nye faststofformer af mesoprogestiner 11beta-[4E-(hydroxyiminomethyl) phenyl]-17alfa-methoxymethyl-17beta-methoxy-östra-4,9-dien-3-on - Google Patents

Nye faststofformer af mesoprogestiner 11beta-[4E-(hydroxyiminomethyl) phenyl]-17alfa-methoxymethyl-17beta-methoxy-östra-4,9-dien-3-on

Info

Publication number: DK1292607T3
Authority: DK; Denmark
Prior art keywords: 11beta; 17alpha; hydroxyiminomethyl; 17beta; methoxymethyl
Prior art date: 2000-05-23

Application number

DK01929632T

Other languages

Danish (da)

English (en)

Inventor

Detlef Grawe

Peter Hoesel

Uwe Mueller

Gabriele Winter

Original Assignee

Bayer Schering Pharma Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-05-23

Filing date

2001-05-09

Publication date

2008-10-13

2001-05-09 Application filed by Bayer Schering Pharma Ag filed Critical Bayer Schering Pharma Ag

2008-10-13 Application granted granted Critical

2008-10-13 Publication of DK1292607T3 publication Critical patent/DK1292607T3/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/36—Antigestagens
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0077—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom
- C07J41/0083—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom substituted in position 11-beta by an optionally substituted phenyl group not further condensed with other rings

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Gynecology & Obstetrics (AREA)
Pregnancy & Childbirth (AREA)
Diabetes (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

DK01929632T 2000-05-23 2001-05-09 Nye faststofformer af mesoprogestiner 11beta-[4E-(hydroxyiminomethyl) phenyl]-17alfa-methoxymethyl-17beta-methoxy-östra-4,9-dien-3-on DK1292607T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP00110887A EP1157996A1 (fr)	2000-05-23	2000-05-23	Nouveaux formes solides du mesoprogestin 11beta-(4E-(hxdroxyiminomethyl)-phenyl)-17alpha-methoxymethyl-17beta-methoxy-estra-4,9-dien-3-on
PCT/EP2001/005237 WO2001090137A2 (fr)	2000-05-23	2001-05-09	Nouvelles formes solides de mesoprogestine 11beta-[4e-(hydroxyiminomethyl)-phenyle]-17alpha-methoxymethyle-17beta-methoxy-estra-4,9-diene-3-one

Publications (1)

Publication Number	Publication Date
DK1292607T3 true DK1292607T3 (da)	2008-10-13

Family

ID=8168805

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK01929632T DK1292607T3 (da)	2000-05-23	2001-05-09	Nye faststofformer af mesoprogestiner 11beta-[4E-(hydroxyiminomethyl) phenyl]-17alfa-methoxymethyl-17beta-methoxy-östra-4,9-dien-3-on

Country Status (30)

Country	Link
US (1)	US7799770B2 (fr)
EP (3)	EP1157996A1 (fr)
JP (1)	JP2003534350A (fr)
KR (1)	KR100553292B1 (fr)
CN (1)	CN100384867C (fr)
AT (1)	ATE397617T1 (fr)
AU (2)	AU2001256344B2 (fr)
BG (1)	BG65968B1 (fr)
BR (1)	BR0111058A (fr)
CA (1)	CA2409869C (fr)
CZ (1)	CZ2003620A3 (fr)
DE (1)	DE50114012D1 (fr)
DK (1)	DK1292607T3 (fr)
EA (1)	EA005623B1 (fr)
EC (2)	ECSP024358A (fr)
ES (1)	ES2307613T3 (fr)
HR (2)	HRP20080423A2 (fr)
HU (1)	HUP0301956A3 (fr)
IL (2)	IL152868A0 (fr)
ME (1)	MEP15608A (fr)
MX (1)	MXPA02011524A (fr)
NO (1)	NO327004B1 (fr)
NZ (1)	NZ522768A (fr)
PL (1)	PL358789A1 (fr)
PT (1)	PT1292607E (fr)
RS (1)	RS50493B (fr)
SK (1)	SK2922003A3 (fr)
UA (1)	UA73988C2 (fr)
WO (1)	WO2001090137A2 (fr)
ZA (1)	ZA200209322B (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE10218107A1 (de) *	2002-04-23	2003-11-20	Jenapharm Gmbh	Verfahren zum Herstellen von Kristallen von Steroiden, danach erhältliche Kristalle und deren Verwendung in pharmazeutischen Formulierungen
DE10218109A1 (de) *	2002-04-23	2003-11-20	Jenapharm Gmbh	Verfahren zum Herstellen von Kristallen, danach erhältliche Kristalle und deren Verwendung in pharmazeutischen Formulierungen
EP1838717A2 (fr) *	2005-01-18	2007-10-03	Teva Gyógyszergyár Zártköruen Muködo Részvenytarsaság	Formes amorphes et cristallines de d'hydrochlorure de dorzolamide et leurs procedes de fabrication
DE102006018888A1 (de) *	2006-04-18	2007-10-25	Bayer Schering Pharma Ag	Verfahren zur Herstellung von 4-[17beta-Methoxy-17alpha-methoxymethyl-3-oxoestra-4,9-dien-11beta-yl]benzaldehyd-(E)-oxims (Asoprisnil)
US20090054387A1 (en) *	2006-04-18	2009-02-26	Detlef Grawe	Method for preparing 4-[17beta-methoxy-17alpha-methoxymethyl-3-oxestra-4,9-dien-11beta-yl]benzaldehyde (E)-oxime (asoprisnil)
EP1862468A1 (fr) *	2006-06-02	2007-12-05	Bayer Schering Pharma Aktiengesellschaft	11beta-(4-Acetylphenyle)-20,20,21,21,21-pentafluor-17-hydroxy-19-nor-17alpha-pregna-4,9-dien-3-one crystalline
DE102009034366A1 (de)	2009-07-20	2011-01-27	Bayer Schering Pharma Aktiengesellschaft	17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-methylenoxyalkylenaryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
DE102009034368A1 (de)	2009-07-20	2011-01-27	Bayer Schering Pharma Aktiengesellschaft	17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-acyloxyalkylenphenyl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
DE102009034367A1 (de)	2009-07-20	2011-01-27	Bayer Schering Pharma Aktiengesellschaft	17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-benzyliden-Derivate, Verfahren zu deren Herstellung und deren Verwendung zur Behandlung von Krankheiten
DE102009034362A1 (de)	2009-07-20	2011-01-27	Bayer Schering Pharma Aktiengesellschaft	17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-aryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
DE102009034525A1 (de)	2009-07-21	2011-01-27	Bayer Schering Pharma Aktiengesellschaft	17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-aryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
DE102009034526A1 (de)	2009-07-21	2011-02-10	Bayer Schering Pharma Aktiengesellschaft	17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-ethinylphenyl-Derivate, Verfahren zu deren Herstellung und deren Verwendung zur Behandlung von Krankheiten
DE102010007722A1 (de)	2010-02-10	2011-08-11	Bayer Schering Pharma Aktiengesellschaft, 13353	Progesteronrezeptorantagonisten
DE102010007719A1 (de)	2010-02-10	2011-08-11	Bayer Schering Pharma Aktiengesellschaft, 13353	Progesteronrezeptorantagonisten

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE4332283A1 (de) *	1993-09-20	1995-04-13	Jenapharm Gmbh	Neue 11-Benzaldoximestradien-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE19610667C2 (de) *	1996-03-08	1998-04-09	Schering Ag	(Z)-11ß-[4-(Dimethylamino)phenyl]17ß-hydroxy-17alpha-(3-hydroxy-1-propenyl)estr-4-en-3-on als kristallines Ansolvat
WO2001009116A2 (fr) *	1999-07-29	2001-02-08	Eli Lilly And Company	NOUVELLE FORME CRISTALLINE DE CHLORHYDRATE DE 6-HYDROXY-3-(4-[2-(PIPERIDIN-1-YL)ETHOXY]PHENOXY)-2-(4-METHOXYPHENYL)BENZO[b]THIOPHENE

2000
- 2000-05-23 EP EP00110887A patent/EP1157996A1/fr not_active Withdrawn
2001
- 2001-05-09 AT AT01929632T patent/ATE397617T1/de not_active IP Right Cessation
- 2001-05-09 KR KR1020027015762A patent/KR100553292B1/ko not_active Expired - Fee Related
- 2001-05-09 HU HU0301956A patent/HUP0301956A3/hu unknown
- 2001-05-09 CA CA002409869A patent/CA2409869C/fr not_active Expired - Lifetime
- 2001-05-09 RS YUP-887/02A patent/RS50493B/sr unknown
- 2001-05-09 ME MEP-156/08A patent/MEP15608A/xx unknown
- 2001-05-09 HR HR20080423A patent/HRP20080423A2/xx not_active Application Discontinuation
- 2001-05-09 HR HR20021032A patent/HRP20021032B1/xx not_active IP Right Cessation
- 2001-05-09 US US10/296,463 patent/US7799770B2/en active Active
- 2001-05-09 ES ES01929632T patent/ES2307613T3/es not_active Expired - Lifetime
- 2001-05-09 SK SK292-2003A patent/SK2922003A3/sk not_active Application Discontinuation
- 2001-05-09 PL PL01358789A patent/PL358789A1/xx not_active IP Right Cessation
- 2001-05-09 MX MXPA02011524A patent/MXPA02011524A/es active IP Right Grant
- 2001-05-09 BR BR0111058-6A patent/BR0111058A/pt not_active IP Right Cessation
- 2001-05-09 AU AU2001256344A patent/AU2001256344B2/en not_active Ceased
- 2001-05-09 DE DE50114012T patent/DE50114012D1/de not_active Expired - Lifetime
- 2001-05-09 WO PCT/EP2001/005237 patent/WO2001090137A2/fr not_active Ceased
- 2001-05-09 NZ NZ522768A patent/NZ522768A/en unknown
- 2001-05-09 AU AU5634401A patent/AU5634401A/xx active Pending
- 2001-05-09 EP EP07115136A patent/EP1862469A2/fr not_active Withdrawn
- 2001-05-09 IL IL15286801A patent/IL152868A0/xx unknown
- 2001-05-09 DK DK01929632T patent/DK1292607T3/da active
- 2001-05-09 CN CNB018099394A patent/CN100384867C/zh not_active Expired - Fee Related
- 2001-05-09 JP JP2001586324A patent/JP2003534350A/ja active Pending
- 2001-05-09 EP EP01929632A patent/EP1292607B1/fr not_active Expired - Lifetime
- 2001-05-09 CZ CZ2003620A patent/CZ2003620A3/cs unknown
- 2001-05-09 EA EA200201192A patent/EA005623B1/ru not_active IP Right Cessation
- 2001-05-09 PT PT01929632T patent/PT1292607E/pt unknown
- 2001-09-05 UA UA20021210147A patent/UA73988C2/uk unknown
2002
- 2002-11-14 IL IL152868A patent/IL152868A/en not_active IP Right Cessation
- 2002-11-15 ZA ZA200209322A patent/ZA200209322B/en unknown
- 2002-11-22 EC EC2002004358A patent/ECSP024358A/es unknown
- 2002-11-22 NO NO20025613A patent/NO327004B1/no not_active IP Right Cessation
2003
- 2003-02-14 BG BG107557A patent/BG65968B1/bg unknown
2008
- 2008-10-22 EC EC2008004358A patent/ECSP084358A/es unknown

Also Published As

Publication number	Publication date
NO327004B1 (no)	2009-04-06
ECSP084358A (es)	2008-11-27
CA2409869A1 (fr)	2002-11-20
EP1292607A2 (fr)	2003-03-19
HUP0301956A3 (en)	2010-03-29
BR0111058A (pt)	2003-04-15
YU88702A (sh)	2006-01-16
CA2409869C (fr)	2009-02-03
KR100553292B1 (ko)	2006-02-22
AU2001256344B2 (en)	2007-01-25
BG107557A (bg)	2004-01-30
NO20025613D0 (no)	2002-11-22
CN1430624A (zh)	2003-07-16
CZ2003620A3 (cs)	2003-08-13
HUP0301956A2 (hu)	2003-09-29
RS50493B (sr)	2010-03-02
ES2307613T3 (es)	2008-12-01
MEP15608A (en)	2010-06-10
US7799770B2 (en)	2010-09-21
AU5634401A (en)	2001-12-03
SK2922003A3 (en)	2003-08-05
MXPA02011524A (es)	2004-09-10
NO20025613L (no)	2002-11-22
NZ522768A (en)	2005-03-24
DE50114012D1 (en)	2008-07-17
EP1157996A1 (fr)	2001-11-28
ECSP024358A (es)	2003-03-31
BG65968B1 (bg)	2010-07-30
IL152868A (en)	2009-08-03
WO2001090137A3 (fr)	2002-04-04
EP1862469A2 (fr)	2007-12-05
EP1292607B1 (fr)	2008-06-04
HRP20021032B1 (hr)	2008-09-30
HRP20080423A2 (en)	2008-10-31
IL152868A0 (en)	2003-06-24
CN100384867C (zh)	2008-04-30
JP2003534350A (ja)	2003-11-18
PT1292607E (pt)	2008-09-15
KR20030028742A (ko)	2003-04-10
US20040006241A1 (en)	2004-01-08
EA200201192A1 (ru)	2003-06-26
AU2001256344B8 (en)	2001-12-03
UA73988C2 (en)	2005-10-17
WO2001090137A2 (fr)	2001-11-29
PL358789A1 (en)	2004-08-23
ZA200209322B (en)	2005-03-10
HRP20021032A2 (en)	2005-02-28
ATE397617T1 (de)	2008-06-15
EA005623B1 (ru)	2005-04-28

Publication	Publication Date	Title
DK1292607T3 (da)	2008-10-13	Nye faststofformer af mesoprogestiner 11beta-[4E-(hydroxyiminomethyl) phenyl]-17alfa-methoxymethyl-17beta-methoxy-östra-4,9-dien-3-on
BR0315372A (pt)	2005-08-23	Repetidor de translação de frequência, e, método para translação de frequência
RU2009127723A (ru)	2011-01-27	Способ и система сброса устройства беспроводной сети и беспроводное сетевое устройство
RU2002119587A (ru)	2004-02-27	Устройство для доставки лекарственных средств, обладающих антипрогестиновыми свойствами
AR039329A1 (es)	2005-02-16	Derivados de triazol, antagonistas de receptor de taquicinina
DK1562976T3 (da)	2010-08-16	Syntese af estetrol via estron-afledte steroider
RU2007115076A (ru)	2008-10-27	Устройство и способ связи
EP2016690A4 (fr)	2010-01-06	Procédé et dispositif de demande de permission d'envoyer des données multimédia et procédé et dispositif de commande de service en temps réel par activation d'un bouton
TW201204094A (en)	2012-01-16	Method and system for determining a location of an access point based on association of the access point with a communication device having a known location
DE69902687D1 (de)	2002-10-02	Hörhilfegerätsystem und hörhilfegerät zur in situ-anpassung
BRPI0700669A (pt)	2007-11-27	método para ajuste de tempo preciso de um dispositivo de comunicação pelo ar e um dispositivo de comunicação correspondente
RU2009109148A (ru)	2010-09-27	Способ поддержки согласованных услуг связи
AU2001256344A1 (en)	2002-02-21	Novel solid body forms of mesoprogestin 11beta-[4e-(hydroxyiminomethyl)-phenyl]-17alpha-methoxymethy -17beta-methoxy-estra-4,9-dien-3-one
JP2009224905A5 (fr)	2011-04-28
IS7513A (is)	2004-10-20	Indól afleiður og notkun þeirra sem CB2 viðtaka bindlar
TR199902929T2 (xx)	2000-06-21	Yeni proses.
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ATE420661T1 (de)	2009-01-15	Zellproliferation-inhibitoren
ATE317700T1 (de)	2006-03-15	Verwendung von (11beta, 17beta)-11-(1,3- benzodioxol-5-yl)-17-hydroxy-17-(1-propinyl)- estra-4,9-dien-3-on zur behandlung von schweren depressionen
PE20070182A1 (es)	2007-03-06	Derivados cianopirrol-fenil amida como moduladores del receptor de progesterona
MXPA03000845A (es)	2004-04-05	Estrogenos substituidos por 16alfa-metilo o etilo.
ATE277071T1 (de)	2004-10-15	Durch 11-beta-aryl-17,17-spirothiolan substituierte steroide
JP5312422B2 (ja)	2013-10-09	移動通信方法及びシステム
TWI307060B (fr)	2009-03-01