NO20025613D0 - Nye faststoff-former av mesoprogestin 11<beta>-[4E- (hydroksyiminometyl)-fenyl]-17<alfa>-metoksymetyl-17<beta>-metoksyöstra-4,9-dien-3-on - Google Patents

Nye faststoff-former av mesoprogestin 11<beta>-[4E- (hydroksyiminometyl)-fenyl]-17<alfa>-metoksymetyl-17<beta>-metoksyöstra-4,9-dien-3-on

Info

Publication number: NO20025613D0
Authority: NO; Norway
Prior art keywords: hydroxyiminomethyl; methoxymethyl; phenyl; mesoprogestin; beta
Prior art date: 2000-05-23

Application number

NO20025613A

Other languages

English (en)

Other versions

NO20025613L (no

NO327004B1 (no

Inventor

Detlef Grawe

Peter Hoesel

Uwe Mueller

Gabriele Winter

Original Assignee

Schering Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-05-23

Filing date

2002-11-22

Publication date

2002-11-22

2002-11-22 Application filed by Schering Ag filed Critical Schering Ag

2002-11-22 Publication of NO20025613D0 publication Critical patent/NO20025613D0/no

2002-11-22 Publication of NO20025613L publication Critical patent/NO20025613L/no

2009-04-06 Publication of NO327004B1 publication Critical patent/NO327004B1/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/36—Antigestagens
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0077—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom
- C07J41/0083—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom substituted in position 11-beta by an optionally substituted phenyl group not further condensed with other rings

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Reproductive Health (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Endocrinology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Gynecology & Obstetrics (AREA)
Pregnancy & Childbirth (AREA)
Diabetes (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

NO20025613A 2000-05-23 2002-11-22 Nye faststoff-former av mesoprogestin 11<beta>-[4E-(hydroksyiminometyl)-fenyl]-17<alfa>-metoksymetyl-17<beta>-metoksyostra-4,9-dien-3-on NO327004B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP00110887A EP1157996A1 (de)	2000-05-23	2000-05-23	Neue Festkörperformen des Mesoprogestins 11Beta-[4E-(Hydroxyiminomethyl)-phenyl]-17Alpha-methoxymethyl-17Beta-methoxy-estra-4,9-dien-3-on
PCT/EP2001/005237 WO2001090137A2 (de)	2000-05-23	2001-05-09	NEUE FESTKÖRPERFORMEN DES MESOPROGESTINS 11β-[4E-(HYDROXYIMINOMETHYL)-PHENYL]-17α-METHOXYMETHYL-17β-METHOXY-ESTRA-4,9-DIEN-3-ON

Publications (3)

Publication Number	Publication Date
NO20025613D0 true NO20025613D0 (no)	2002-11-22
NO20025613L NO20025613L (no)	2002-11-22
NO327004B1 NO327004B1 (no)	2009-04-06

Family

ID=8168805

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20025613A NO327004B1 (no)	2000-05-23	2002-11-22	Nye faststoff-former av mesoprogestin 11<beta>-[4E-(hydroksyiminometyl)-fenyl]-17<alfa>-metoksymetyl-17<beta>-metoksyostra-4,9-dien-3-on

Country Status (30)

Country	Link
US (1)	US7799770B2 (no)
EP (3)	EP1157996A1 (no)
JP (1)	JP2003534350A (no)
KR (1)	KR100553292B1 (no)
CN (1)	CN100384867C (no)
AT (1)	ATE397617T1 (no)
AU (2)	AU2001256344B2 (no)
BG (1)	BG65968B1 (no)
BR (1)	BR0111058A (no)
CA (1)	CA2409869C (no)
CZ (1)	CZ2003620A3 (no)
DE (1)	DE50114012D1 (no)
DK (1)	DK1292607T3 (no)
EA (1)	EA005623B1 (no)
EC (2)	ECSP024358A (no)
ES (1)	ES2307613T3 (no)
HR (2)	HRP20021032B1 (no)
HU (1)	HUP0301956A3 (no)
IL (2)	IL152868A0 (no)
ME (1)	MEP15608A (no)
MX (1)	MXPA02011524A (no)
NO (1)	NO327004B1 (no)
NZ (1)	NZ522768A (no)
PL (1)	PL358789A1 (no)
PT (1)	PT1292607E (no)
RS (1)	RS50493B (no)
SK (1)	SK2922003A3 (no)
UA (1)	UA73988C2 (no)
WO (1)	WO2001090137A2 (no)
ZA (1)	ZA200209322B (no)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE10218109A1 (de) *	2002-04-23	2003-11-20	Jenapharm Gmbh	Verfahren zum Herstellen von Kristallen, danach erhältliche Kristalle und deren Verwendung in pharmazeutischen Formulierungen
DE10218107A1 (de) *	2002-04-23	2003-11-20	Jenapharm Gmbh	Verfahren zum Herstellen von Kristallen von Steroiden, danach erhältliche Kristalle und deren Verwendung in pharmazeutischen Formulierungen
EP1838717A2 (en) *	2005-01-18	2007-10-03	Teva Gyógyszergyár Zártköruen Muködo Részvenytarsaság	Amorphous and crystalline forms of dorzolamide hydrochloride and processes of making same
DE102006018888A1 (de) *	2006-04-18	2007-10-25	Bayer Schering Pharma Ag	Verfahren zur Herstellung von 4-[17beta-Methoxy-17alpha-methoxymethyl-3-oxoestra-4,9-dien-11beta-yl]benzaldehyd-(E)-oxims (Asoprisnil)
US20090054387A1 (en)	2006-04-18	2009-02-26	Detlef Grawe	Method for preparing 4-[17beta-methoxy-17alpha-methoxymethyl-3-oxestra-4,9-dien-11beta-yl]benzaldehyde (E)-oxime (asoprisnil)
EP1862468A1 (de) *	2006-06-02	2007-12-05	Bayer Schering Pharma Aktiengesellschaft	Kristallines 11beta-(4-Acetylphenyl)-20,20,21,21,21-pentafluor-17-hydroxy-19-nor-17alpha-pregna-4,9-dien-3-on
DE102009034368A1 (de)	2009-07-20	2011-01-27	Bayer Schering Pharma Aktiengesellschaft	17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-acyloxyalkylenphenyl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
DE102009034362A1 (de)	2009-07-20	2011-01-27	Bayer Schering Pharma Aktiengesellschaft	17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-aryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
DE102009034367A1 (de)	2009-07-20	2011-01-27	Bayer Schering Pharma Aktiengesellschaft	17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-benzyliden-Derivate, Verfahren zu deren Herstellung und deren Verwendung zur Behandlung von Krankheiten
DE102009034366A1 (de)	2009-07-20	2011-01-27	Bayer Schering Pharma Aktiengesellschaft	17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-methylenoxyalkylenaryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
DE102009034525A1 (de)	2009-07-21	2011-01-27	Bayer Schering Pharma Aktiengesellschaft	17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-aryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
DE102009034526A1 (de)	2009-07-21	2011-02-10	Bayer Schering Pharma Aktiengesellschaft	17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-ethinylphenyl-Derivate, Verfahren zu deren Herstellung und deren Verwendung zur Behandlung von Krankheiten
DE102010007719A1 (de)	2010-02-10	2011-08-11	Bayer Schering Pharma Aktiengesellschaft, 13353	Progesteronrezeptorantagonisten
DE102010007722A1 (de)	2010-02-10	2011-08-11	Bayer Schering Pharma Aktiengesellschaft, 13353	Progesteronrezeptorantagonisten

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE4332283A1 (de) *	1993-09-20	1995-04-13	Jenapharm Gmbh	Neue 11-Benzaldoximestradien-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE19610667C2 (de) *	1996-03-08	1998-04-09	Schering Ag	(Z)-11ß-[4-(Dimethylamino)phenyl]17ß-hydroxy-17alpha-(3-hydroxy-1-propenyl)estr-4-en-3-on als kristallines Ansolvat
WO2001009116A2 (en) *	1999-07-29	2001-02-08	Eli Lilly And Company	A NOVEL CRYSTALLINE FORM OF 6-HYDROXY-3- (4-[2-(PIPERIDIN-1-YL) ETHOXY]PHENOXY)- 2-(4-METHOXYPHENYL)BENZO[b]THIOPHENE HYDROCHLORIDE

2000
- 2000-05-23 EP EP00110887A patent/EP1157996A1/de not_active Withdrawn
2001
- 2001-05-09 CA CA002409869A patent/CA2409869C/en not_active Expired - Lifetime
- 2001-05-09 DK DK01929632T patent/DK1292607T3/da active
- 2001-05-09 HU HU0301956A patent/HUP0301956A3/hu unknown
- 2001-05-09 KR KR1020027015762A patent/KR100553292B1/ko not_active Expired - Fee Related
- 2001-05-09 EP EP07115136A patent/EP1862469A2/de not_active Withdrawn
- 2001-05-09 EA EA200201192A patent/EA005623B1/ru not_active IP Right Cessation
- 2001-05-09 CZ CZ2003620A patent/CZ2003620A3/cs unknown
- 2001-05-09 RS YUP-887/02A patent/RS50493B/sr unknown
- 2001-05-09 PL PL01358789A patent/PL358789A1/xx not_active IP Right Cessation
- 2001-05-09 HR HR20021032A patent/HRP20021032B1/xx not_active IP Right Cessation
- 2001-05-09 NZ NZ522768A patent/NZ522768A/en unknown
- 2001-05-09 US US10/296,463 patent/US7799770B2/en active Active
- 2001-05-09 BR BR0111058-6A patent/BR0111058A/pt not_active IP Right Cessation
- 2001-05-09 CN CNB018099394A patent/CN100384867C/zh not_active Expired - Fee Related
- 2001-05-09 ME MEP-156/08A patent/MEP15608A/xx unknown
- 2001-05-09 IL IL15286801A patent/IL152868A0/xx unknown
- 2001-05-09 ES ES01929632T patent/ES2307613T3/es not_active Expired - Lifetime
- 2001-05-09 WO PCT/EP2001/005237 patent/WO2001090137A2/de not_active Ceased
- 2001-05-09 JP JP2001586324A patent/JP2003534350A/ja active Pending
- 2001-05-09 HR HR20080423A patent/HRP20080423A2/xx not_active Application Discontinuation
- 2001-05-09 DE DE50114012T patent/DE50114012D1/de not_active Expired - Lifetime
- 2001-05-09 PT PT01929632T patent/PT1292607E/pt unknown
- 2001-05-09 SK SK292-2003A patent/SK2922003A3/sk not_active Application Discontinuation
- 2001-05-09 AU AU2001256344A patent/AU2001256344B2/en not_active Ceased
- 2001-05-09 EP EP01929632A patent/EP1292607B1/de not_active Expired - Lifetime
- 2001-05-09 MX MXPA02011524A patent/MXPA02011524A/es active IP Right Grant
- 2001-05-09 AU AU5634401A patent/AU5634401A/xx active Pending
- 2001-05-09 AT AT01929632T patent/ATE397617T1/de not_active IP Right Cessation
- 2001-09-05 UA UA20021210147A patent/UA73988C2/uk unknown
2002
- 2002-11-14 IL IL152868A patent/IL152868A/en not_active IP Right Cessation
- 2002-11-15 ZA ZA200209322A patent/ZA200209322B/en unknown
- 2002-11-22 NO NO20025613A patent/NO327004B1/no not_active IP Right Cessation
- 2002-11-22 EC EC2002004358A patent/ECSP024358A/es unknown
2003
- 2003-02-14 BG BG107557A patent/BG65968B1/bg unknown
2008
- 2008-10-22 EC EC2008004358A patent/ECSP084358A/es unknown

Also Published As

Publication number	Publication date
PL358789A1 (en)	2004-08-23
EP1157996A1 (de)	2001-11-28
DE50114012D1 (en)	2008-07-17
AU2001256344B8 (en)	2001-12-03
MEP15608A (en)	2010-06-10
CN1430624A (zh)	2003-07-16
CZ2003620A3 (cs)	2003-08-13
EP1292607B1 (de)	2008-06-04
KR20030028742A (ko)	2003-04-10
HUP0301956A3 (en)	2010-03-29
DK1292607T3 (da)	2008-10-13
EP1292607A2 (de)	2003-03-19
BR0111058A (pt)	2003-04-15
HRP20021032B1 (hr)	2008-09-30
CA2409869A1 (en)	2002-11-20
WO2001090137A2 (de)	2001-11-29
WO2001090137A3 (de)	2002-04-04
SK2922003A3 (en)	2003-08-05
MXPA02011524A (es)	2004-09-10
ZA200209322B (en)	2005-03-10
BG65968B1 (bg)	2010-07-30
HUP0301956A2 (hu)	2003-09-29
EA200201192A1 (ru)	2003-06-26
PT1292607E (pt)	2008-09-15
RS50493B (sr)	2010-03-02
NO20025613L (no)	2002-11-22
NO327004B1 (no)	2009-04-06
UA73988C2 (en)	2005-10-17
EA005623B1 (ru)	2005-04-28
IL152868A0 (en)	2003-06-24
IL152868A (en)	2009-08-03
ES2307613T3 (es)	2008-12-01
ECSP084358A (es)	2008-11-27
AU2001256344B2 (en)	2007-01-25
BG107557A (bg)	2004-01-30
ATE397617T1 (de)	2008-06-15
KR100553292B1 (ko)	2006-02-22
HRP20080423A2 (en)	2008-10-31
CN100384867C (zh)	2008-04-30
JP2003534350A (ja)	2003-11-18
HRP20021032A2 (en)	2005-02-28
CA2409869C (en)	2009-02-03
US20040006241A1 (en)	2004-01-08
EP1862469A2 (de)	2007-12-05
US7799770B2 (en)	2010-09-21
ECSP024358A (es)	2003-03-31
YU88702A (sh)	2006-01-16
NZ522768A (en)	2005-03-24
AU5634401A (en)	2001-12-03

Publication	Publication Date	Title
NO20025613L (no)	2002-11-22	Nye faststoff-former av mesoprogestin 11<beta>-[4E- (hydroksyiminometyl)-fenyl]-17<alfa>-metoksymetyl-17<beta>-metoksyöstra-4,9-dien-3-on
CZ296328B6 (cs)	2006-02-15	17alfa-fluoralkylsteroidy, farmaceutické prostredky tyto látky obsahující a jejich pouzití
HU208021B (en)	1993-07-28	Process for producing 13-alyl-11-beta-phenyl-gonane derivatives and pharmaceutical compositions containing them
NO178264B (no)	1995-11-13	11-beta-substituerte progesteronanaloger
FR2618783A1 (fr)	1989-02-03	Nouveaux 17-aryle steroides, leurs procedes et des intermediaires de preparation comme medicaments et les compositions pharmaceutiques les renfermant
Padwa et al.	1993	Bimolecular cycloaddition reactions of isomünchnones derived from the rhodium (II) catalyzed cyclization of diazo pyrrolidinones
IL94819A (en)	1995-03-30	History of B11-Aryl-4-Asterin, processes for their preparation and pharmaceutical preparations containing them
JP6556125B2 (ja)	2019-08-07	１７β−ヒドロキシステロイドデヒドロゲナーゼの阻害剤としての治療的に活性な１７−窒素置換エストラトリエンチアゾール誘導体
Jin et al.	2007	Copper-Catalyzed Cyclization of Steroidal Acylaminoacetylenes: Syntheses of Novel 11β-Aryl-17, 17-spiro [(4 ‘H, 5 ‘-methylene) oxazol]-Substituted Steroids
HUT67308A (en)	1995-03-28	19-nor steroids,pharmaceutical compositions containing them and process for producing them and intermediates
NZ515353A (en)	2004-03-26	Cyclothiocarbamate derivatives as progesterone receptor modulators
CA1321578C (en)	1993-08-24	19-substituted progesterone derivatives useful as 19-hydroxylase inhibitors
US3202686A (en)	1965-08-24	Preparation of 13-alkylgona-1, 3, 5 (10), 8, 14-pentaenes
AU7511700A (en)	2001-04-10	Non-aromatic estrogenic steroids with a hydrocarbon substituent in position 11
EP1773862A1 (en)	2007-04-18	Estrogen receptor modulators
SE8602449D0 (sv)	1986-05-29	11-beta substituted steroids and process for their preparation
CA2297112A1 (en)	1999-03-04	Dicyclanil polymorphs and hydrates and their preparation
US4496555A (en)	1985-01-29	Compounds and compositions for inhibiting estrogen sulfotransferase transferase activity, process and novel intermediates therein
Klimstra et al.	1965	Anabolic Agents. A-Ring Conjugated Enone Androstane Derivatives1a
Ikegawa et al.	1982	Synthesis of 3, 6α, 16α-trihydroxy-1, 3, 5 (10)-estratrien-17-one 6-hemisuccinate and [6, 73H]-3, 16α-dihydroxy-1, 3, 5 (10)-estratrien-17-one
Mattox et al.	1976	Preparation of 3β, 16β-dihydroxyandrost-5-en-17-one: Stabilization of its α-ketolic group toward alkali by formation of a semicarbazone
Rao et al.	1999	Synthesis of N-desmethyl derivatives of 17α-acetoxy-11β-(4-N, N-dimethylaminophenyl)-19-norpregna-4, 9-diene-3, 20-dione and mifepristone1: substrates for the synthesis of radioligands
Zhang et al.	2002	Synthesis and crystal structure of β-lactam derivatives of 1, 5-benzothiazepines under microwave irradition
Quadrelli et al.	0	Stereo-and Regioselectivity in Nitrile Oxide Cycloaddition Reactions to Norethisterone Acetate as Dipolarophile
ES476922A1 (es)	1979-07-16	Un procedimiento para la obtencion de cis-3-(4-hidroximetil-1-metil-2-piperidil)indol.

Legal Events

Date	Code	Title	Description
2011-12-27	MM1K	Lapsed by not paying the annual fees