DK1114821T3 - Benzopyraner og disses anvendelse som terapeutiske midler - Google Patents

Benzopyraner og disses anvendelse som terapeutiske midler

Info

Publication number: DK1114821T3
Authority: DK; Denmark
Prior art keywords: benzopyrans; therapeutic agents; therapeutic; agents
Prior art date: 1994-06-10

Application number

DK01200801T

Other languages

Danish (da)

English (en)

Inventor

Wai Ngor Chan

Helen Kate Ann Morgan

Mervyn Thompson

John Morris Evans

Original Assignee

Smithkline Beecham Plc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-06-10

Filing date

1995-05-31

Publication date

2004-02-02

1994-06-10 Priority claimed from GB9411632A external-priority patent/GB9411632D0/en

1994-06-13 Priority claimed from GB9411798A external-priority patent/GB9411798D0/en

1995-05-31 Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc

2004-02-02 Application granted granted Critical

2004-02-02 Publication of DK1114821T3 publication Critical patent/DK1114821T3/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C07D311/68—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with nitrogen atoms directly attached in position 4
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Psychiatry (AREA)
Addiction (AREA)
Pain & Pain Management (AREA)
Vascular Medicine (AREA)
Cardiology (AREA)
Urology & Nephrology (AREA)
Psychology (AREA)
Heart & Thoracic Surgery (AREA)
Hospice & Palliative Care (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Pyrane Compounds (AREA)

DK01200801T 1994-06-10 1995-05-31 Benzopyraner og disses anvendelse som terapeutiske midler DK1114821T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB9411632A GB9411632D0 (en)	1994-06-10	1994-06-10	Novel treatment
GB9411798A GB9411798D0 (en)	1994-06-13	1994-06-13	Novel treatment

Publications (1)

Publication Number	Publication Date
DK1114821T3 true DK1114821T3 (da)	2004-02-02

Family

ID=26305044

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
DK95921798T DK0764157T3 (da)	1994-06-10	1995-05-31	Benzopyraner og deres anvendelse som terapeutiske midler
DK01200801T DK1114821T3 (da)	1994-06-10	1995-05-31	Benzopyraner og disses anvendelse som terapeutiske midler

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
DK95921798T DK0764157T3 (da)	1994-06-10	1995-05-31	Benzopyraner og deres anvendelse som terapeutiske midler

Country Status (29)

Country	Link
US (1)	US5760074A (fr)
EP (2)	EP1114821B1 (fr)
JP (2)	JP3575767B2 (fr)
KR (1)	KR100397721B1 (fr)
CN (2)	CN1174975C (fr)
AP (1)	AP714A (fr)
AT (2)	ATE211469T1 (fr)
AU (1)	AU701060B2 (fr)
BG (1)	BG63339B1 (fr)
BR (1)	BR9507980A (fr)
CA (1)	CA2192480C (fr)
CY (1)	CY2508B1 (fr)
CZ (1)	CZ286081B6 (fr)
DE (2)	DE69531801T2 (fr)
DK (2)	DK0764157T3 (fr)
ES (2)	ES2207590T3 (fr)
FI (1)	FI120686B (fr)
HK (1)	HK1039115B (fr)
HU (1)	HUT76136A (fr)
NO (1)	NO315651B1 (fr)
NZ (1)	NZ287872A (fr)
OA (1)	OA10593A (fr)
PL (1)	PL188134B1 (fr)
PT (2)	PT764157E (fr)
RO (1)	RO113463B1 (fr)
SG (1)	SG67930A1 (fr)
SI (2)	SI1114821T1 (fr)
SK (1)	SK281456B6 (fr)
WO (1)	WO1995034545A1 (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20010021780A1 (en) *	1992-12-11	2001-09-13	Smithkline Beecham P.L.C.	Pharmaceutical composition containing bicyclic type compounds
GB9411635D0 (en) *	1994-06-10	1994-08-03	Smithkline Beecham Plc	Novel treatment
GB9619492D0 (en) *	1996-09-18	1996-10-30	Smithkline Beecham Plc	Novel treatment
US6492415B2 (en) *	1996-09-18	2002-12-10	Smithkline Beecham P.L.C.	Use of benzopyranols to treat neurological disorders
GB9726543D0 (en) *	1997-12-16	1998-02-11	Smithkline Beecham Plc	Novel compositions
GB9813949D0 (en) *	1998-06-29	1998-08-26	Smithkline Beecham Plc	Novel compounds
GB0028697D0 (en) *	2000-11-23	2001-01-10	S P A	Novel process
CA2602267A1 (fr) *	2005-04-04	2006-10-12	Takeda Pharmaceutical Company Limited	Utilisation du ramelteon pour le traitement ou la prevention de troubles de depression et d'anxiete
US20110319482A1 (en) *	2008-06-05	2011-12-29	Peter Blower	Novel treatments
US20130281524A1 (en) *	2008-06-05	2013-10-24	Peter Blower	Novel treatments
RU2012124837A (ru)	2009-12-03	2014-01-10	Проксимэджен ЛТД	Лечение аллодинии и гипералгезии
RU2012124838A (ru)	2009-12-03	2014-01-10	Проксимэджен ЛТД	Лечение инфекционных заболеваний
AU2013285164A1 (en)	2012-07-03	2015-01-22	Proximagen Limited	Pro-drug compounds
GB201304814D0 (en) *	2013-03-15	2013-05-01	Proximagen Ltd	Pro-drug compounds
GB201322934D0 (en)	2013-12-23	2014-02-12	Proximagen Ltd	Prodrug compounds
GB201322932D0 (en) *	2013-12-23	2014-02-12	Proximagen Ltd	Pro-drug compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0126311B1 (fr) *	1983-05-18	1989-09-13	Beecham Group Plc	Dérivés de benzopyrane.
GB9112721D0 (en) *	1991-06-13	1991-07-31	Smithkline Beecham Plc	Novel treatment
WO1994013657A1 (fr) *	1992-12-11	1994-06-23	Smithkline Beecham Plc	Composition pharmaceutique contenant des composes du type bicyclique
EP0673373A1 (fr) *	1992-12-11	1995-09-27	Smithkline Beecham Plc	Composes bicycliques a activite pharmaceutique
US5536718A (en) *	1995-01-17	1996-07-16	American Cyanamid Company	Tricyclic benzazepine vasopressin antagonists

1995
- 1995-05-31 WO PCT/EP1995/002076 patent/WO1995034545A1/fr not_active Ceased
- 1995-05-31 RO RO96-02326A patent/RO113463B1/ro unknown
- 1995-05-31 SG SG1996008495A patent/SG67930A1/en unknown
- 1995-05-31 PT PT95921798T patent/PT764157E/pt unknown
- 1995-05-31 AT AT95921798T patent/ATE211469T1/de active
- 1995-05-31 BR BR9507980A patent/BR9507980A/pt not_active IP Right Cessation
- 1995-05-31 ES ES01200801T patent/ES2207590T3/es not_active Expired - Lifetime
- 1995-05-31 CZ CZ19963617A patent/CZ286081B6/cs not_active IP Right Cessation
- 1995-05-31 DK DK95921798T patent/DK0764157T3/da active
- 1995-05-31 CN CNB951944134A patent/CN1174975C/zh not_active Expired - Lifetime
- 1995-05-31 JP JP50155696A patent/JP3575767B2/ja not_active Expired - Lifetime
- 1995-05-31 SK SK1587-96A patent/SK281456B6/sk not_active IP Right Cessation
- 1995-05-31 AU AU26727/95A patent/AU701060B2/en not_active Expired
- 1995-05-31 EP EP01200801A patent/EP1114821B1/fr not_active Expired - Lifetime
- 1995-05-31 DK DK01200801T patent/DK1114821T3/da active
- 1995-05-31 AP APAP/P/1996/000889A patent/AP714A/en active
- 1995-05-31 SI SI9530691T patent/SI1114821T1/xx unknown
- 1995-05-31 EP EP95921798A patent/EP0764157B1/fr not_active Expired - Lifetime
- 1995-05-31 PT PT01200801T patent/PT1114821E/pt unknown
- 1995-05-31 DE DE69531801T patent/DE69531801T2/de not_active Expired - Lifetime
- 1995-05-31 PL PL95317579A patent/PL188134B1/pl unknown
- 1995-05-31 HU HU9603415A patent/HUT76136A/hu not_active Application Discontinuation
- 1995-05-31 NZ NZ287872A patent/NZ287872A/en not_active IP Right Cessation
- 1995-05-31 CN CNB01124366XA patent/CN1234702C/zh not_active Expired - Lifetime
- 1995-05-31 DE DE69524871T patent/DE69524871T2/de not_active Expired - Lifetime
- 1995-05-31 SI SI9530579T patent/SI0764157T1/xx unknown
- 1995-05-31 KR KR1019960707048A patent/KR100397721B1/ko not_active Expired - Lifetime
- 1995-05-31 CA CA002192480A patent/CA2192480C/fr not_active Expired - Lifetime
- 1995-05-31 ES ES95921798T patent/ES2170798T3/es not_active Expired - Lifetime
- 1995-05-31 AT AT01200801T patent/ATE250052T1/de active
- 1995-06-02 US US08/460,151 patent/US5760074A/en not_active Expired - Lifetime
1996
- 1996-12-09 NO NO19965260A patent/NO315651B1/no not_active IP Right Cessation
- 1996-12-10 OA OA60933A patent/OA10593A/en unknown
- 1996-12-10 BG BG101040A patent/BG63339B1/bg unknown
- 1996-12-10 FI FI964936A patent/FI120686B/fi not_active IP Right Cessation
2002
- 2002-01-10 HK HK02100192.4A patent/HK1039115B/en not_active IP Right Cessation
2003
- 2003-01-23 JP JP2003014984A patent/JP2003238554A/ja active Pending
2005
- 2005-03-15 CY CY0500017A patent/CY2508B1/xx unknown

Also Published As

Publication number	Publication date
SG67930A1 (en)	1999-10-19
FI964936L (fi)	1997-02-06
AP9600889A0 (en)	1997-01-31
JP2003238554A (ja)	2003-08-27
JP3575767B2 (ja)	2004-10-13
CN1234702C (zh)	2006-01-04
FI120686B (fi)	2010-01-29
NO315651B1 (no)	2003-10-06
BG63339B1 (bg)	2001-10-31
SK281456B6 (sk)	2001-03-12
AU701060B2 (en)	1999-01-21
KR100397721B1 (ko)	2004-04-28
WO1995034545A1 (fr)	1995-12-21
CA2192480C (fr)	2007-07-24
BG101040A (en)	1997-08-29
ES2170798T3 (es)	2002-08-16
NO965260L (no)	1997-02-06
CZ286081B6 (cs)	2000-01-12
ATE211469T1 (de)	2002-01-15
JPH10501251A (ja)	1998-02-03
SK158796A3 (en)	1997-07-09
SI1114821T1 (en)	2004-02-29
NZ287872A (en)	1998-05-27
PT764157E (pt)	2002-06-28
BR9507980A (pt)	1997-08-12
ES2207590T3 (es)	2004-06-01
CA2192480A1 (fr)	1995-12-21
DE69531801T2 (de)	2004-07-01
CY2508B1 (en)	2005-12-23
DE69524871D1 (de)	2002-02-07
NO965260D0 (no)	1996-12-09
HK1039115B (en)	2004-08-13
AP714A (en)	1998-12-23
DK0764157T3 (da)	2002-04-22
CN1174975C (zh)	2004-11-10
DE69524871T2 (de)	2002-08-22
HUT76136A (en)	1997-06-30
PL317579A1 (en)	1997-04-14
CN1336369A (zh)	2002-02-20
HK1039115A1 (en)	2002-04-12
HK1001286A1 (en)	1998-06-12
US5760074A (en)	1998-06-02
OA10593A (en)	2002-07-10
EP1114821B1 (fr)	2003-09-17
FI964936A0 (fi)	1996-12-10
RO113463B1 (ro)	1998-07-30
PL188134B1 (pl)	2004-12-31
EP0764157B1 (fr)	2002-01-02
CZ361796A3 (en)	1997-08-13
PT1114821E (pt)	2004-02-27
ATE250052T1 (de)	2003-10-15
DE69531801D1 (de)	2003-10-23
HU9603415D0 (en)	1997-02-28
CN1154698A (zh)	1997-07-16
EP1114821A1 (fr)	2001-07-11
SI0764157T1 (en)	2002-06-30
EP0764157A1 (fr)	1997-03-26
AU2672795A (en)	1996-01-05

Publication	Publication Date	Title
NO985977D0 (no)	1998-12-18	Spiro-piperidinderivater og deres anvendelse som terapeutiske midler
NO992806L (no)	1999-08-09	Terapeutiske midler
DK0906292T3 (da)	2003-10-27	Triazolylmercaptider og deres anvendelse som mikrobicider
FI970762A0 (fi)	1997-02-24	Terapiassa käyttökelpoiset spiroatsabisykliset yhdisteet
KR970701725A (ko)	1997-04-12	사람 파골세포 유래 카텝신(Human osteoclast-derived cathepsin)
DE69526237D1 (de)	2002-05-08	Chirurgische gesichtsmaske
IS4481A (is)	1997-05-12	Díhýdrópyramídín og notkun þeirra
DE69417229D1 (de)	1999-04-22	Chirurgiegerät
ATA126393A (de)	1995-07-15	Chirurgisches handstück
NO971811D0 (no)	1997-04-18	Bicykliske tetrahydropyrazolopyridiner og deres anvendelse som legemidler
DE69524138D1 (de)	2002-01-10	Hautbehandlungsmittel
DK1114821T3 (da)	2004-02-02	Benzopyraner og disses anvendelse som terapeutiske midler
NO972256D0 (no)	1997-05-16	O-Benzyloksimeterderivater og deres anvendelse som pesticider
FR2722416B1 (fr)	1996-10-04	Extincteur
FI961339A7 (fi)	1996-03-22	Triaryylieteenijohdannaiset käytettäväksi hoidossa
ITMI950222A0 (it)	1995-02-08	Tessuto
NO963939D0 (no)	1996-09-19	N-aryl og N-alkylsulfonylaminaler som pesticider
ZA954732B (en)	1996-05-06	Benzopyrans and their use as therapeutic agents
KR950026706U (ko)	1995-10-16	치료용 발열기
MD281F1 (ro)	1995-09-30	Masajor magnetodinamic
KR950003058U (ko)	1995-02-16	건강의자
KR950013358U (ko)	1995-06-15	안마기
KR960019879U (ko)	1996-07-18	체력단련용 의자
IT234822Y1 (it)	2000-03-16	Agenda terapeutica
KR940022052U (ko)	1994-10-19	쑥뜸 받침대