DK1150686T3 - Direkte komprimerbar matrix til kontrolleret frigivelse af daglige enkeltdoser af clarithromycin - Google Patents
Direkte komprimerbar matrix til kontrolleret frigivelse af daglige enkeltdoser af clarithromycinInfo
- Publication number
- DK1150686T3 DK1150686T3 DK00905514T DK00905514T DK1150686T3 DK 1150686 T3 DK1150686 T3 DK 1150686T3 DK 00905514 T DK00905514 T DK 00905514T DK 00905514 T DK00905514 T DK 00905514T DK 1150686 T3 DK1150686 T3 DK 1150686T3
- Authority
- DK
- Denmark
- Prior art keywords
- clarithromycin
- controlled release
- single doses
- direct compressible
- daily single
- Prior art date
Links
- AGOYDEPGAOXOCK-KCBOHYOISA-N clarithromycin Chemical compound O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@](C)([C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)OC)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 AGOYDEPGAOXOCK-KCBOHYOISA-N 0.000 title abstract 2
- 229960002626 clarithromycin Drugs 0.000 title abstract 2
- 238000013270 controlled release Methods 0.000 title abstract 2
- 239000011159 matrix material Substances 0.000 title abstract 2
- 239000013543 active substance Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000004094 surface-active agent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SI9900039A SI20150A (sl) | 1999-02-19 | 1999-02-19 | Direktno stisljivi matriks za nadzorovano sproščanje celodnevne doze klaritromicina |
| PCT/SI2000/000002 WO2000048607A1 (en) | 1999-02-19 | 2000-02-17 | Directly compressible matrix for controlled release of single daily doses of clarithromycin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1150686T3 true DK1150686T3 (da) | 2005-04-04 |
Family
ID=20432410
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK00905514T DK1150686T3 (da) | 1999-02-19 | 2000-02-17 | Direkte komprimerbar matrix til kontrolleret frigivelse af daglige enkeltdoser af clarithromycin |
Country Status (21)
| Country | Link |
|---|---|
| EP (1) | EP1150686B1 (da) |
| AT (1) | ATE286736T1 (da) |
| AU (1) | AU776912B2 (da) |
| BG (1) | BG65324B1 (da) |
| CY (1) | CY1107454T1 (da) |
| CZ (1) | CZ302781B6 (da) |
| DE (1) | DE60017361T2 (da) |
| DK (1) | DK1150686T3 (da) |
| EE (1) | EE05422B1 (da) |
| ES (1) | ES2235834T3 (da) |
| HR (1) | HRP20010684B1 (da) |
| HU (1) | HUP0105481A3 (da) |
| PL (1) | PL196665B1 (da) |
| PT (1) | PT1150686E (da) |
| RS (1) | RS50298B (da) |
| RU (1) | RU2237480C2 (da) |
| SI (2) | SI20150A (da) |
| SK (1) | SK287525B6 (da) |
| TR (1) | TR200102396T2 (da) |
| UA (1) | UA74778C2 (da) |
| WO (1) | WO2000048607A1 (da) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TR200000054A2 (tr) * | 2000-01-05 | 2001-08-21 | Sanovel İlaç San. Ve Ti̇c. Anoni̇m Şi̇rketi̇ | Klaritromisin içeren sürekli salım sağlayan tablet formülasyonları. |
| US6565882B2 (en) | 2000-02-24 | 2003-05-20 | Advancis Pharmaceutical Corp | Antibiotic composition with inhibitor |
| US6544555B2 (en) | 2000-02-24 | 2003-04-08 | Advancis Pharmaceutical Corp. | Antibiotic product, use and formulation thereof |
| IN192748B (da) * | 2000-08-29 | 2004-05-15 | Ranbaxy Lab Ltd | |
| US20020068078A1 (en) | 2000-10-13 | 2002-06-06 | Rudnic Edward M. | Antifungal product, use and formulation thereof |
| US6541014B2 (en) | 2000-10-13 | 2003-04-01 | Advancis Pharmaceutical Corp. | Antiviral product, use and formulation thereof |
| WO2003017981A1 (en) | 2001-08-29 | 2003-03-06 | Ranbaxy Laboratories Limited | Controlled release formulation of clarithromycin or tinidazol |
| US6642276B2 (en) * | 2001-10-01 | 2003-11-04 | M/S Ind-Swift Limited | Controlled release macrolide pharmaceutical formulations |
| SE0103369D0 (sv) * | 2001-10-09 | 2001-10-09 | Astrazeneca Ab | Pharmaceutical formulation |
| EP1443910A1 (en) | 2001-11-02 | 2004-08-11 | Wockhardt Limited | Controlled release compositions for macrolide antimicrobial agents |
| CA2481271A1 (en) * | 2002-04-03 | 2003-10-09 | Ranbaxy Laboratories Limited | Clarithromycin formulations having improved bioavailability |
| US20060083759A1 (en) * | 2002-07-17 | 2006-04-20 | Aleksander Resman | Stabilization of the profile of release of active substances from a formulation |
| EP1534238A1 (en) * | 2002-07-29 | 2005-06-01 | ALZA Corporation | Formulations and dosage forms for controlled delivery of topiramate |
| US20050232995A1 (en) | 2002-07-29 | 2005-10-20 | Yam Nyomi V | Methods and dosage forms for controlled delivery of paliperidone and risperidone |
| EP1653924A4 (en) | 2003-08-12 | 2009-09-09 | Middlebrook Pharmaceuticals In | ANTIBIOTICS, USE AND FORMULATION ASSOCIATED |
| WO2005023221A1 (en) * | 2003-09-05 | 2005-03-17 | Ranbaxy Laboratories Limited | Clarithromycin formulations having improved biovailability |
| RU2268051C2 (ru) * | 2003-12-15 | 2006-01-20 | Закрытое акционерное общество "Фармацевтическое предприятие "Оболенское" | Лекарственная форма, обладающая бактериостатическим действием, и способ ее изготовления |
| US7943585B2 (en) * | 2003-12-22 | 2011-05-17 | Sandoz, Inc. | Extended release antibiotic composition |
| AU2005235237A1 (en) * | 2004-03-24 | 2005-11-03 | Lupin Limited | Clarithromycin extended release formulation |
| EP2283824B1 (en) | 2009-07-30 | 2017-04-19 | Special Products Line S.p.A. | Compositions and formulations based on swellable matrices for sustained release of poorly soluble drugs such as clarithromycin |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4331803A (en) * | 1980-06-04 | 1982-05-25 | Taisho Pharmaceutical Co., Ltd. | Novel erythromycin compounds |
| JPS60163823A (ja) * | 1984-02-03 | 1985-08-26 | Taisho Pharmaceut Co Ltd | 経口投与製剤 |
| JPS60214796A (ja) * | 1984-04-06 | 1985-10-28 | Taisho Pharmaceut Co Ltd | ６−０−メチルエリスロマイシン類の製法 |
| JPS63188621A (ja) * | 1987-01-30 | 1988-08-04 | Taisho Pharmaceut Co Ltd | 矯味経口製剤 |
| US4808411A (en) * | 1987-06-05 | 1989-02-28 | Abbott Laboratories | Antibiotic-polymer compositions |
| IL87219A0 (en) * | 1987-08-07 | 1988-12-30 | Abbott Lab | Erythromycin formulations for oral administration |
| JP2553882B2 (ja) * | 1987-08-08 | 1996-11-13 | 富士写真光機株式会社 | 走査結像光学系 |
| US5599556A (en) * | 1991-12-31 | 1997-02-04 | Abbott Laboratories | Prolamine coatings for taste masking |
| ES2199981T3 (es) * | 1994-02-16 | 2004-03-01 | Abbott Laboratories | Modo de preparacion de formulaciones farmaceuticas de particulas finas. |
-
1999
- 1999-02-19 SI SI9900039A patent/SI20150A/sl not_active IP Right Cessation
-
2000
- 2000-02-17 EE EEP200100433A patent/EE05422B1/xx not_active IP Right Cessation
- 2000-02-17 AT AT00905514T patent/ATE286736T1/de active
- 2000-02-17 ES ES00905514T patent/ES2235834T3/es not_active Expired - Lifetime
- 2000-02-17 WO PCT/SI2000/000002 patent/WO2000048607A1/en not_active Ceased
- 2000-02-17 PL PL350419A patent/PL196665B1/pl unknown
- 2000-02-17 CZ CZ20012964A patent/CZ302781B6/cs not_active IP Right Cessation
- 2000-02-17 EP EP00905514A patent/EP1150686B1/en not_active Expired - Lifetime
- 2000-02-17 AU AU27049/00A patent/AU776912B2/en not_active Ceased
- 2000-02-17 RS YUP-592/01A patent/RS50298B/sr unknown
- 2000-02-17 DK DK00905514T patent/DK1150686T3/da active
- 2000-02-17 RU RU2001125667A patent/RU2237480C2/ru not_active IP Right Cessation
- 2000-02-17 UA UA2001096230A patent/UA74778C2/uk unknown
- 2000-02-17 DE DE60017361T patent/DE60017361T2/de not_active Expired - Lifetime
- 2000-02-17 SI SI200030647T patent/SI1150686T1/xx unknown
- 2000-02-17 PT PT00905514T patent/PT1150686E/pt unknown
- 2000-02-17 HU HU0105481A patent/HUP0105481A3/hu unknown
- 2000-02-17 HR HR20010684A patent/HRP20010684B1/xx not_active IP Right Cessation
- 2000-02-17 TR TR2001/02396T patent/TR200102396T2/xx unknown
- 2000-02-17 SK SK1197-2001A patent/SK287525B6/sk not_active IP Right Cessation
-
2001
- 2001-09-19 BG BG105914A patent/BG65324B1/bg unknown
-
2005
- 2005-03-10 CY CY20051100330T patent/CY1107454T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PL350419A1 (en) | 2002-12-16 |
| WO2000048607A1 (en) | 2000-08-24 |
| RS50298B (sr) | 2009-09-08 |
| HUP0105481A3 (en) | 2003-04-28 |
| RU2237480C2 (ru) | 2004-10-10 |
| HRP20010684B1 (hr) | 2011-01-31 |
| EP1150686A1 (en) | 2001-11-07 |
| HRP20010684A2 (en) | 2002-10-31 |
| ES2235834T3 (es) | 2005-07-16 |
| TR200102396T2 (tr) | 2002-01-21 |
| SI20150A (sl) | 2000-08-31 |
| SI1150686T1 (en) | 2005-06-30 |
| SK11972001A3 (sk) | 2002-02-05 |
| BG65324B1 (bg) | 2008-02-29 |
| EE200100433A (et) | 2002-12-16 |
| HUP0105481A2 (hu) | 2002-05-29 |
| EP1150686B1 (en) | 2005-01-12 |
| DE60017361D1 (de) | 2005-02-17 |
| AU2704900A (en) | 2000-09-04 |
| DE60017361T2 (de) | 2005-12-22 |
| AU776912B2 (en) | 2004-09-23 |
| CY1107454T1 (el) | 2012-12-19 |
| ATE286736T1 (de) | 2005-01-15 |
| EE05422B1 (et) | 2011-06-15 |
| PT1150686E (pt) | 2005-05-31 |
| CZ302781B6 (cs) | 2011-11-02 |
| YU59201A (sh) | 2004-07-15 |
| PL196665B1 (pl) | 2008-01-31 |
| CZ20012964A3 (cs) | 2002-01-16 |
| SK287525B6 (sk) | 2011-01-04 |
| BG105914A (bg) | 2002-05-31 |
| UA74778C2 (en) | 2006-02-15 |
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