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DK1023069T3 - Nikotinsammensætninger og fremgangsmåder til fremstilling deraf - Google Patents

Nikotinsammensætninger og fremgangsmåder til fremstilling deraf

Info

Publication number
DK1023069T3
DK1023069T3 DK98945685T DK98945685T DK1023069T3 DK 1023069 T3 DK1023069 T3 DK 1023069T3 DK 98945685 T DK98945685 T DK 98945685T DK 98945685 T DK98945685 T DK 98945685T DK 1023069 T3 DK1023069 T3 DK 1023069T3
Authority
DK
Denmark
Prior art keywords
offspring
precursors
liquid crystals
dispersions
nicotine
Prior art date
Application number
DK98945685T
Other languages
Danish (da)
English (en)
Inventor
Sven Boerje Andersson
Stefan Jonn
Tomas Landh
Original Assignee
Pharmacia Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Ab filed Critical Pharmacia Ab
Application granted granted Critical
Publication of DK1023069T3 publication Critical patent/DK1023069T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1274Non-vesicle bilayer structures, e.g. liquid crystals, tubules, cubic phases or cochleates; Sponge phases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/465Nicotine; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34Tobacco-abuse

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Dispersion Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DK98945685T 1997-09-25 1998-09-15 Nikotinsammensætninger og fremgangsmåder til fremstilling deraf DK1023069T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9703458A SE9703458D0 (sv) 1997-09-25 1997-09-25 Nicotine compositions and methods of formulation thereof
PCT/SE1998/001632 WO1999015171A1 (fr) 1997-09-25 1998-09-15 Compositions de nicotine et leur procede de formulation

Publications (1)

Publication Number Publication Date
DK1023069T3 true DK1023069T3 (da) 2004-03-08

Family

ID=20408364

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98945685T DK1023069T3 (da) 1997-09-25 1998-09-15 Nikotinsammensætninger og fremgangsmåder til fremstilling deraf

Country Status (22)

Country Link
EP (1) EP1023069B1 (fr)
JP (1) JP2001517624A (fr)
KR (1) KR20010024305A (fr)
CN (1) CN1123343C (fr)
AT (1) ATE253362T1 (fr)
AU (1) AU733619B2 (fr)
BR (1) BR9815395A (fr)
CA (1) CA2304042A1 (fr)
DE (1) DE69819548T2 (fr)
DK (1) DK1023069T3 (fr)
EE (1) EE200000154A (fr)
ES (1) ES2210817T3 (fr)
FI (1) FI20000692L (fr)
HU (1) HUP0004802A3 (fr)
MX (1) MXPA00002955A (fr)
NO (1) NO20001540L (fr)
NZ (1) NZ503408A (fr)
PT (1) PT1023069E (fr)
RU (1) RU2201747C2 (fr)
SE (1) SE9703458D0 (fr)
WO (1) WO1999015171A1 (fr)
ZA (1) ZA988794B (fr)

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US6638621B2 (en) * 2000-08-16 2003-10-28 Lyotropic Therapeutics, Inc. Coated particles, methods of making and using
US8256433B2 (en) 1999-07-16 2012-09-04 Aradigm Corporation Systems and methods for effecting cessation of tobacco use
US6799576B2 (en) 1999-07-16 2004-10-05 Aradigm Corporation System for effecting smoking cessation
AT409219B (de) * 1999-08-13 2002-06-25 Red Bull Gmbh Verwendung von nikotin zum herstellen von arzneimitteln
KR100381622B1 (ko) * 2000-08-30 2003-04-26 디디에스텍주식회사 자극성을 줄인 염기성 약물의 구강 투여 조성물
DE10057769A1 (de) * 2000-11-22 2002-05-23 Beiersdorf Ag Haarpflegeprodukte mit einem Gehalt an dispersen Flüssigkristallen, welche kubische Phasen darstellen
SE0102197D0 (sv) * 2001-06-20 2001-06-20 Pharmacia Ab New product and use and manufacture thereof
SE521512C2 (sv) 2001-06-25 2003-11-11 Niconovum Ab Anordning för administrering av en substans till främre delen av en individs munhåla
AU2003209750A1 (en) * 2002-03-30 2003-10-13 Gunther Beisel Preparation containing fatty acid, used for reducing appetite, satiating, and/or reducing weight
US20040002520A1 (en) * 2002-07-01 2004-01-01 Soderlund Patrick L. Composition and method for cessation of Nicotine cravings
KR100443722B1 (ko) * 2002-09-26 2004-08-09 이용원 니코틴을 함유한 하드츄잉캔디 및 그의 제조방법
ATE359075T1 (de) 2002-12-20 2007-05-15 Niconovum Ab Chemisch und physikalisch stabiles teilchenförmiges material enthaltend nikotin und microcrystalline cellulose
FR2851470B1 (fr) * 2003-02-20 2007-11-16 Besins Int Belgique Composition pharmaceutique pour administration transdermique ou transmuqueuse
US9498454B2 (en) 2003-02-24 2016-11-22 Pharmaceutical Productions Inc. Transmucosal drug delivery system
US9358296B2 (en) 2003-02-24 2016-06-07 Pharmaceutical Productions Inc. Transmucosal drug delivery system
KR20120066688A (ko) 2003-02-24 2012-06-22 파마슈티칼 프로덕션스, 인크. 경점막 약물 전달 시스템
US10172810B2 (en) 2003-02-24 2019-01-08 Pharmaceutical Productions, Inc. Transmucosal ketamine delivery composition
US9254294B2 (en) 2003-02-24 2016-02-09 Pharmaceutical Productions Inc. Transmucosal hormone delivery system
RU2250057C2 (ru) * 2003-05-16 2005-04-20 Квасенков Олег Иванович Способ производства некурительного табачного изделия
RU2250051C2 (ru) * 2003-05-16 2005-04-20 Квасенков Олег Иванович Способ производства некурительного табачного изделия
RU2250052C2 (ru) * 2003-05-16 2005-04-20 Квасенков Олег Иванович Способ производства некурительного табачного изделия
RU2351315C2 (ru) * 2003-07-24 2009-04-10 Смитклайн Бичам Корпорейшн Пленки, растворяющиеся в полости рта
GB0322033D0 (en) * 2003-09-19 2003-10-22 Camurus Ab Composition
US8469036B2 (en) 2003-11-07 2013-06-25 U.S. Smokeless Tobacco Company Llc Tobacco compositions
US8627828B2 (en) 2003-11-07 2014-01-14 U.S. Smokeless Tobacco Company Llc Tobacco compositions
US7125954B2 (en) 2005-01-27 2006-10-24 General Electric Company Method for producing polyether polymers
US20080219935A1 (en) * 2005-07-08 2008-09-11 Sang-Hoon Kwak Phase Transitive Breath Care Products
AU2007224584A1 (en) 2006-03-16 2007-09-20 Niconovum Ab Improved snuff composition
US20100247653A1 (en) * 2006-04-11 2010-09-30 Hans Lautenschlager Nanoparticles containing nicotine and/or cotinine, dispersions, and use thereof
US20080287507A1 (en) * 2007-05-16 2008-11-20 John Hedenstrom Nicotine containing toiletry waters
GB2469792A (en) * 2009-04-23 2010-11-03 Calvin John Ross Oil-based pharmaceutical formulation for sublingual delivery
GB2476471A (en) * 2009-12-22 2011-06-29 Norwich Pharma Technologies Ltd Cotinine formulation for the treatment of obesity
US8846725B2 (en) * 2011-01-24 2014-09-30 Quadex Pharmaceuticals, Llc Highly penetrating compositions and methods for treating pathogen-induced disordered tissues
CN102552405B (zh) * 2012-03-21 2013-10-16 张伟 一种肛周术后麻醉镇痛的药物组合物的制备方法
CN103040741B (zh) * 2012-12-11 2014-11-05 中山大学 溶致液晶的前体混悬液及其制备方法
WO2014135630A1 (fr) * 2013-03-07 2014-09-12 Danmarks Tekniske Universitet Systèmes d'administration par voie oro-muqueuse de nano-microparticules d'un principe actif
ES2999088T3 (en) * 2013-05-06 2025-02-24 Juul Labs Inc Nicotine salt formulations for aerosol devices and methods thereof
WO2015090337A1 (fr) * 2013-12-20 2015-06-25 Fertin Pharma A/S Composition de poudre de nicotine
CN105828819A (zh) * 2014-04-08 2016-08-03 桑萨(巴巴多斯)公司 烟碱制剂及其制备方法
GB201414919D0 (en) * 2014-08-21 2014-10-08 Corbitt Terence Simon Formulations for transmucosal delivery
CN108472251B (zh) * 2016-01-13 2022-02-01 株式会社 Lg 生活健康 口腔用制剂
CN108323791B (zh) * 2018-01-03 2021-02-12 云南中烟工业有限责任公司 一种尼古丁-氧化锌复合物、其制备方法及包含其的烟草制品
AU2019256805B2 (en) * 2018-04-16 2022-03-03 Poviva Corp. Compositions infused with nicotine compounds and methods of use thereof
CN109125251B (zh) * 2018-09-10 2021-08-13 武汉百纳礼康生物制药有限公司 一种包载蛋白类药物的温敏性液晶凝胶制剂及其制备方法
KR102186704B1 (ko) * 2019-02-18 2020-12-04 (주)아이엠디팜 서방성 지질 전구 제제 및 이를 포함하는 지질 용액 형태의 서방성 주사용 약학 조성물
LU101520B1 (en) * 2019-12-02 2021-06-07 Herrera Arturo Solis (S)-3-[1-Methylpyrrolidin-2-yl]pyridine, analogues thereof, precursors thereof, or its derivatives, for the use as a pharmaceutical in form of a homogeneous, viscous, semi-solid topical medication and topical medication
LU101511B1 (en) * 2019-12-02 2021-06-04 Herrera Arturo Solis (S)-3-[1-Methylpyrrolidin-2-yl]pyridine, analogues thereof, precursors thereof, or its derivatives, for the use as a pharmaceutical in form of a parenteral administration and a process for the preparation of an injectable substance
US12137723B2 (en) 2019-12-09 2024-11-12 Nicoventures Trading Limited Oral products with active ingredient combinations
NL2031332B1 (en) 2022-03-18 2023-09-29 Plethora Therapeutics B V Transmucosal delivery of psychoactive compounds
NL2031331B1 (en) 2022-03-18 2023-09-29 Plethora Therapeutics B V Transmucosal delivery of a short-acting psychedelic compound
EP4570082A1 (fr) * 2023-12-15 2025-06-18 Contraf-Nicotex-Tobacco GmbH Produit oral pour l'administration de nicotine comprenant un sel de nicotine d'un acide gras

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US5371109A (en) * 1986-07-01 1994-12-06 Drilletten Ab Controlled release composition for a biologically active material dissolved or dispersed in an L2-phase
IL86170A (en) * 1987-05-01 1992-12-01 Elan Transdermal Ltd Preparations and compositions comprising nicotine for percutaneous administration
US4908213A (en) * 1989-02-21 1990-03-13 Schering Corporation Transdermal delivery of nicotine
GB2230439A (en) * 1989-04-20 1990-10-24 Alec Stanley Walter Shaw Nicotine lozenges
AU2699892A (en) * 1991-10-04 1993-05-03 Gs Biochem Ab Particles, method of preparing said particles and uses thereof
CA2231273A1 (fr) * 1995-10-12 1997-04-17 Lise Sylvest Nielsen Composition pharmaceutique pour l'administration d'un principe actif sur ou au travers d'une surface cutanee ou muqueuse

Also Published As

Publication number Publication date
NZ503408A (en) 2004-12-24
ES2210817T3 (es) 2004-07-01
RU2201747C2 (ru) 2003-04-10
DE69819548T2 (de) 2004-08-12
ATE253362T1 (de) 2003-11-15
PT1023069E (pt) 2004-02-27
NO20001540D0 (no) 2000-03-24
CN1123343C (zh) 2003-10-08
AU733619B2 (en) 2001-05-17
BR9815395A (pt) 2000-11-14
ZA988794B (en) 1999-04-01
HUP0004802A3 (en) 2001-12-28
CA2304042A1 (fr) 1999-04-01
HUP0004802A2 (hu) 2001-05-28
KR20010024305A (ko) 2001-03-26
AU9287298A (en) 1999-04-12
FI20000692A7 (fi) 2000-03-24
SE9703458D0 (sv) 1997-09-25
DE69819548D1 (de) 2003-12-11
JP2001517624A (ja) 2001-10-09
CN1278174A (zh) 2000-12-27
EP1023069A1 (fr) 2000-08-02
FI20000692L (fi) 2000-03-24
WO1999015171A1 (fr) 1999-04-01
EE200000154A (et) 2001-02-15
MXPA00002955A (es) 2002-04-24
NO20001540L (no) 2000-05-25
EP1023069B1 (fr) 2003-11-05

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