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DK1001955T3 - 1,2,4-triazolo[4,3-b]pyrido[3,2-d]pyridazinderivater og farmaceutiske præparater, der indeholder dem - Google Patents

1,2,4-triazolo[4,3-b]pyrido[3,2-d]pyridazinderivater og farmaceutiske præparater, der indeholder dem

Info

Publication number
DK1001955T3
DK1001955T3 DK98940218T DK98940218T DK1001955T3 DK 1001955 T3 DK1001955 T3 DK 1001955T3 DK 98940218 T DK98940218 T DK 98940218T DK 98940218 T DK98940218 T DK 98940218T DK 1001955 T3 DK1001955 T3 DK 1001955T3
Authority
DK
Denmark
Prior art keywords
triazolo
pyrido
pharmaceutical compositions
compositions containing
pyridazine derivatives
Prior art date
Application number
DK98940218T
Other languages
Danish (da)
English (en)
Inventor
Ferrer Jordi Gracia
Crespo M Isabel Crespo
Noverola Armando Vega
Garcia Andres Fernandez
Original Assignee
Almirall Prodesfarma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Almirall Prodesfarma Sa filed Critical Almirall Prodesfarma Sa
Application granted granted Critical
Publication of DK1001955T3 publication Critical patent/DK1001955T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Ophthalmology & Optometry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK98940218T 1997-07-29 1998-07-13 1,2,4-triazolo[4,3-b]pyrido[3,2-d]pyridazinderivater og farmaceutiske præparater, der indeholder dem DK1001955T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES009701670A ES2137113B1 (es) 1997-07-29 1997-07-29 Nuevos derivados de triazolo-piridazinas heterociclicos.
PCT/EP1998/004340 WO1999006404A1 (fr) 1997-07-29 1998-07-13 Derives de 1,2,4-triazolo[4,3-b]pyrido[3,2-d]pyridazine et compositions pharmaceutiques a base de ces derives

Publications (1)

Publication Number Publication Date
DK1001955T3 true DK1001955T3 (da) 2001-11-19

Family

ID=8300216

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98940218T DK1001955T3 (da) 1997-07-29 1998-07-13 1,2,4-triazolo[4,3-b]pyrido[3,2-d]pyridazinderivater og farmaceutiske præparater, der indeholder dem

Country Status (35)

Country Link
US (2) US6407108B1 (fr)
EP (1) EP1001955B1 (fr)
JP (1) JP4320118B2 (fr)
KR (1) KR20010022353A (fr)
CN (1) CN1135231C (fr)
AR (1) AR015927A1 (fr)
AT (1) ATE207069T1 (fr)
AU (1) AU737709B2 (fr)
BG (1) BG64448B1 (fr)
BR (1) BR9810829B1 (fr)
CA (1) CA2298935A1 (fr)
CO (1) CO4970780A1 (fr)
CZ (1) CZ290208B6 (fr)
DE (1) DE69802100T2 (fr)
DK (1) DK1001955T3 (fr)
EE (1) EE04313B1 (fr)
EG (1) EG24041A (fr)
ES (2) ES2137113B1 (fr)
HU (1) HUP0004708A3 (fr)
ID (1) ID24506A (fr)
IL (1) IL134081A (fr)
MY (1) MY118796A (fr)
NO (1) NO315118B1 (fr)
NZ (1) NZ502356A (fr)
PE (1) PE111099A1 (fr)
PL (1) PL191031B1 (fr)
PT (1) PT1001955E (fr)
RU (1) RU2202552C2 (fr)
SI (1) SI1001955T1 (fr)
SK (1) SK284046B6 (fr)
TR (1) TR200000243T2 (fr)
TW (1) TW542837B (fr)
UA (1) UA60339C2 (fr)
WO (1) WO1999006404A1 (fr)
ZA (1) ZA986248B (fr)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2792938B1 (fr) * 1999-04-28 2001-07-06 Warner Lambert Co NOUVELLES 1-AMINO TRIAZOLO [4,3-a] QUINAZOLINE-5-ONES INHIBITRICES DE PHOSPHODIESTERASES IV
TR200909479T2 (tr) 1999-08-21 2012-02-21 Nycomed Gmbh Sinerjistik kombinasyon.
WO2002080974A1 (fr) * 2001-04-04 2002-10-17 Sankyo Company, Limited Utilisation medicale d'inhibiteur de production de cytokine
EA008108B1 (ru) * 2001-09-19 2007-04-27 Алтана Фарма Аг Комбинация нспвлс и ингибитора pde-4
FR2832711B1 (fr) * 2001-11-26 2004-01-30 Warner Lambert Co Derives de triazolo [4,3-a] pyrido [2,3-d] pyrimidin-5-ones, compositions les contenant, procede de preparation et utilisation
AU2003277562B2 (en) * 2002-11-06 2009-03-26 Aska Pharmaceutical Co., Ltd. Pyrazolonaphthyridine derivative
ES2211344B1 (es) 2002-12-26 2005-10-01 Almirall Prodesfarma, S.A. Nuevos derivados de piridazin-3(2h)-ona.
MXPA05010373A (es) 2003-04-01 2005-12-05 Applied Research Systems Inhibidores de fosfodiesterasas en infertilidad.
US20050187278A1 (en) * 2003-08-28 2005-08-25 Pharmacia Corporation Treatment or prevention of vascular disorders with Cox-2 inhibitors in combination with cyclic AMP-specific phosphodiesterase inhibitors
RU2246496C1 (ru) * 2003-09-12 2005-02-20 Тец Виктор Вениаминович Вещество с противовирусной и антибактериальной активностью на основе производных 2,8-дитиоксо-1h-пирано[2,3-d, 6,5-d`] дипиримидина и их 10-аза-аналогов
ES2251866B1 (es) 2004-06-18 2007-06-16 Laboratorios Almirall S.A. Nuevos derivados de piridazin-3(2h)-ona.
AU2006258124B8 (en) * 2005-06-10 2010-01-07 Merck Sharp & Dohme Corp. Inhibitors of Akt activity
EP2275095A3 (fr) 2005-08-26 2011-08-17 Braincells, Inc. Neurogenese par modulation des recepteurs muscariniques
EP2258359A3 (fr) 2005-08-26 2011-04-06 Braincells, Inc. Neurogenèse par modulation des récepteurs muscariniques avec sabcomeline
AU2006289838B2 (en) 2005-09-15 2011-08-18 Aska Pharmaceutical Co., Ltd. Heterocyclic compound, and production process and use thereof
CA2625153A1 (fr) 2005-10-21 2007-04-26 Braincells, Inc. Modulation de la neurogenese par inhibition de la pde
CA2625210A1 (fr) 2005-10-31 2007-05-10 Braincells, Inc. Modulation de la neurogenese dont la mediation est assuree par recepteur gaba
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
US7678808B2 (en) 2006-05-09 2010-03-16 Braincells, Inc. 5 HT receptor mediated neurogenesis
JP2009536669A (ja) 2006-05-09 2009-10-15 ブレインセルス，インコーポレイティド アンジオテンシン調節による神経新生
JP2010500365A (ja) 2006-08-07 2010-01-07 インサイト・コーポレイション キナーゼ阻害剤としてのトリアゾロトリアジン
AU2007292848A1 (en) 2006-09-08 2008-03-13 Braincells, Inc. Combinations containing a 4-acylaminopyridine derivative
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
BRPI0719333A2 (pt) 2006-11-22 2014-02-04 Incyte Corp Midazotriazinas e imidazopirimidinas como inbidores de cinase
WO2009089027A1 (fr) * 2008-01-09 2009-07-16 Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Service, National Institutes Of Health Inhibiteurs de phosphodiestérase
BRPI0912882A2 (pt) 2008-05-21 2017-05-16 Incyte Corp sais de 2-flúor-n-metil-4-[7-(quinolin-6-il-metil)-imidazo[1,2-b][1,2,4]triazin-2-il]benzamida e processos relacionados à preparação dos mesmos
EP2196465A1 (fr) 2008-12-15 2010-06-16 Almirall, S.A. Dérivés de (3-oxo)pyridazin-4-ylurée comme inhibiteurs de PDE4
WO2010099217A1 (fr) 2009-02-25 2010-09-02 Braincells, Inc. Modulation de neurogenèse à l'aide de combinaisons de d-cyclosérine
EP2226323A1 (fr) 2009-02-27 2010-09-08 Almirall, S.A. Nouveaux dérivés de tétrahydropyrazolo [3,4-c]isoquinoléine-5-amine
PH12012501361A1 (en) 2009-12-31 2012-10-22 Centro Nac De Investigaciones Oncologicas Cnio Tricyclic compounds for use as kinase inhibitors
MX2012008898A (es) 2010-02-03 2012-11-06 Incyte Corp Imidazo - [1, 2 - b] [1, 2, 4] triazinas como inhibidores de c - met.
EP2380890A1 (fr) 2010-04-23 2011-10-26 Almirall, S.A. Nouveaux dérivés de 7,8-dihydro-1,6-naphthyridin-5(6h)-one comme PDE4 inhibiteurs
EP2394998A1 (fr) 2010-05-31 2011-12-14 Almirall, S.A. Dérivés de 3-(5-Amino-6-oxo-1,6-dihydropyridazin-3-yl)-biphenyl en tant qu'inhibiteurs de la PDE4
WO2012098387A1 (fr) 2011-01-18 2012-07-26 Centro Nacional De Investigaciones Oncológicas (Cnio) Dérivés de triazolo[4,3-b]pyridazines au cycle 6,7 fusionné utilisés en tant qu'inhibiteurs de pim
WO2013005041A1 (fr) 2011-07-07 2013-01-10 Centro Nacional De Investigaciones Oncológicas (Cnio) Composés hétérocycliques tricycliques en tant qu'inhibiteurs de kinases
WO2013005057A1 (fr) 2011-07-07 2013-01-10 Centro Nacional De Investigaciones Oncológicas (Cnio) Nouveaux composés
WO2013004984A1 (fr) 2011-07-07 2013-01-10 Centro Nacional De Investigaciones Oncologicas (Cnio) Composés tricycliques pour l'utilisation en tant qu'inhibiteurs de kinase
WO2013106547A1 (fr) 2012-01-10 2013-07-18 President And Fellows Of Harvard College Composés promoteurs de réplication des cellules bêta et leurs procédés d'utilisation

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3122670A1 (de) 1981-06-06 1982-12-23 Dr. Karl Thomae Gmbh, 7950 Biberach "neue 1,4,9,10-tetrahydro-pyrazolo(4,3-e) pyrido(3,2-b)(1,4)diazepin-10-one, verfahren zu ihrer herstellung und ihre verwendung zur herstellung von pharmazeutischen wirkstoffen"
FI81350C (fi) * 1982-01-18 1990-10-10 Lepetit Spa Analogfoerfarande foer framstaellning av nya, farmakologiskt aktiva 6-substituerade s-triatsolo/3,4-a/ ftalazinderivat.
DE3677445D1 (de) * 1985-09-30 1991-03-14 Ciba Geigy Ag 2-substituierte-e-kondensierte(1,5-c)-pyrimidine, pharmazeutische zubereitungen und ihre verwendung.
JP3120857B2 (ja) * 1990-02-19 2000-12-25 中外製薬株式会社 新規な縮合複素環化合物とこれを用いた抗喘息剤
DE69229874T2 (de) * 1991-10-09 1999-12-09 Syntex (U.S.A.) Inc., Palo Alto Pyrido pyridazinon und pyridazinthionverbindungen mit pde iv inhibierender wirkung
GB9514465D0 (en) 1995-07-14 1995-09-13 Glaxo Lab Sa Chemical compounds
DE19510965A1 (de) * 1995-03-24 1996-09-26 Asta Medica Ag Neue Pyrido/3,2-e/pyrazinone mit antiasthmatischer Wirksamkeit und Verfahren zu deren Herstellung

Also Published As

Publication number Publication date
CZ290208B6 (cs) 2002-06-12
HK1024914A1 (en) 2000-10-27
BR9810829A (pt) 2000-07-25
WO1999006404A1 (fr) 1999-02-11
US20020183326A1 (en) 2002-12-05
DE69802100D1 (de) 2001-11-22
NO315118B1 (no) 2003-07-14
ID24506A (id) 2000-07-20
PT1001955E (pt) 2002-02-28
MY118796A (en) 2005-01-31
TW542837B (en) 2003-07-21
UA60339C2 (uk) 2003-10-15
PL191031B1 (pl) 2006-03-31
IL134081A (en) 2004-02-08
IL134081A0 (en) 2001-04-30
PE111099A1 (es) 1999-11-18
AU8861298A (en) 1999-02-22
US6407108B1 (en) 2002-06-18
CZ2000333A3 (cs) 2000-05-17
NZ502356A (en) 2001-03-30
TR200000243T2 (tr) 2000-07-21
HUP0004708A2 (hu) 2001-07-30
EP1001955B1 (fr) 2001-10-17
CN1266434A (zh) 2000-09-13
BG104112A (en) 2001-01-31
NO20000394L (no) 2000-03-27
BR9810829B1 (pt) 2009-08-11
JP2001512121A (ja) 2001-08-21
SK862000A3 (en) 2000-07-11
JP4320118B2 (ja) 2009-08-26
NO20000394D0 (no) 2000-01-26
CO4970780A1 (es) 2000-11-07
ZA986248B (en) 1999-02-05
DE69802100T2 (de) 2002-03-14
SK284046B6 (sk) 2004-08-03
EG24041A (en) 2008-04-03
ATE207069T1 (de) 2001-11-15
ES2137113B1 (es) 2000-09-16
ES2137113A1 (es) 1999-12-01
EE04313B1 (et) 2004-06-15
ES2162466T3 (es) 2001-12-16
RU2202552C2 (ru) 2003-04-20
PL338214A1 (en) 2000-10-09
AU737709B2 (en) 2001-08-30
AR015927A1 (es) 2001-05-30
BG64448B1 (en) 2005-02-28
SI1001955T1 (en) 2002-02-28
CA2298935A1 (fr) 1999-02-11
HUP0004708A3 (en) 2002-11-28
KR20010022353A (ko) 2001-03-15
EP1001955A1 (fr) 2000-05-24
CN1135231C (zh) 2004-01-21
EE200000052A (et) 2000-10-16

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