[go: up one dir, main page]

DK1051217T3 - System til kontrol af osmotisk medikamentlevering - Google Patents

System til kontrol af osmotisk medikamentlevering

Info

Publication number
DK1051217T3
DK1051217T3 DK98964191T DK98964191T DK1051217T3 DK 1051217 T3 DK1051217 T3 DK 1051217T3 DK 98964191 T DK98964191 T DK 98964191T DK 98964191 T DK98964191 T DK 98964191T DK 1051217 T3 DK1051217 T3 DK 1051217T3
Authority
DK
Denmark
Prior art keywords
drug delivery
osmotic drug
controlling osmotic
controlling
delivery
Prior art date
Application number
DK98964191T
Other languages
English (en)
Inventor
Rupal Ayer
Scott D Jordan
Gregory R Stewart
Stephen A Berry
James B Di Eckenhoff
Original Assignee
Eckenhoff Bonnie J
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eckenhoff Bonnie J, Alza Corp filed Critical Eckenhoff Bonnie J
Application granted granted Critical
Publication of DK1051217T3 publication Critical patent/DK1051217T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14212—Pumping with an aspiration and an expulsion action
    • A61M5/1424—Manually operated pumps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2250/00—Specially adapted for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/0105—Steering means as part of the catheter or advancing means; Markers for positioning
    • A61M25/0108—Steering means as part of the catheter or advancing means; Markers for positioning using radio-opaque or ultrasound markers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/16831—Monitoring, detecting, signalling or eliminating infusion flow anomalies
    • A61M5/1684—Monitoring, detecting, signalling or eliminating infusion flow anomalies by detecting the amount of infusate remaining, e.g. signalling end of infusion

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Vascular Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
DK98964191T 1997-12-31 1998-12-21 System til kontrol af osmotisk medikamentlevering DK1051217T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7017897P 1997-12-31 1997-12-31
PCT/US1998/027208 WO1999033513A1 (en) 1997-12-31 1998-12-21 Osmotic drug delivery monitoring system and method

Publications (1)

Publication Number Publication Date
DK1051217T3 true DK1051217T3 (da) 2003-12-08

Family

ID=22093633

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98964191T DK1051217T3 (da) 1997-12-31 1998-12-21 System til kontrol af osmotisk medikamentlevering

Country Status (13)

Country Link
US (1) US6283953B1 (da)
EP (1) EP1051217B8 (da)
AR (1) AR014231A1 (da)
AT (2) ATE322928T1 (da)
AU (1) AU1937099A (da)
CA (1) CA2316887C (da)
DE (2) DE69834213T2 (da)
DK (1) DK1051217T3 (da)
ES (1) ES2205595T3 (da)
PT (1) PT1051217E (da)
TW (1) TW381974B (da)
WO (1) WO1999033513A1 (da)
ZA (1) ZA9811879B (da)

Families Citing this family (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2196918T3 (es) * 1998-12-31 2003-12-16 Alza Corp Sistema de suministro osmotico dotado de piston con economia de espacio..
CA2390261C (en) * 1999-11-08 2014-04-22 University Of Florida Research Foundation, Inc. Marker detection method and apparatus to monitor drug compliance
US20050054942A1 (en) * 2002-01-22 2005-03-10 Melker Richard J. System and method for therapeutic drug monitoring
US6981947B2 (en) * 2002-01-22 2006-01-03 University Of Florida Research Foundation, Inc. Method and apparatus for monitoring respiratory gases during anesthesia
US7104963B2 (en) * 2002-01-22 2006-09-12 University Of Florida Research Foundation, Inc. Method and apparatus for monitoring intravenous (IV) drug concentration using exhaled breath
US7052854B2 (en) 2001-05-23 2006-05-30 University Of Florida Research Foundation, Inc. Application of nanotechnology and sensor technologies for ex-vivo diagnostics
WO2002095398A1 (en) 2001-05-24 2002-11-28 University Of Florida Method and apparatus for detecting environmental smoke exposure
US20070167853A1 (en) 2002-01-22 2007-07-19 Melker Richard J System and method for monitoring health using exhaled breath
US7927613B2 (en) * 2002-02-15 2011-04-19 University Of South Florida Pharmaceutical co-crystal compositions
WO2003074474A2 (en) 2002-03-01 2003-09-12 University Of South Florida Multiple-component solid phases containing at least one active pharmaceutical ingredient
US20100311701A1 (en) * 2002-02-15 2010-12-09 Transform Pharmaceuticals, Inc Pharmaceutical Co-Crystal Compositions
WO2004000284A1 (en) * 2002-06-21 2003-12-31 Transform Pharmaceuticals, Inc. Pharmaceutical compositions with improved dissolution
US7790905B2 (en) * 2002-02-15 2010-09-07 Mcneil-Ppc, Inc. Pharmaceutical propylene glycol solvate compositions
US7731947B2 (en) * 2003-11-17 2010-06-08 Intarcia Therapeutics, Inc. Composition and dosage form comprising an interferon particle formulation and suspending vehicle
US8183290B2 (en) 2002-12-30 2012-05-22 Mcneil-Ppc, Inc. Pharmaceutically acceptable propylene glycol solvate of naproxen
EP2339328A3 (en) 2002-12-30 2011-07-13 Transform Pharmaceuticals, Inc. Pharmaceutical co-crystal compositions of celecoxib
AU2003272270A1 (en) 2003-02-28 2004-09-28 The Regents Of The University Of Michigan Pharmaceutical co-crystal compositions of drugs such as carbamazeptine, celecoxib, olanzapine, itraconazole, topiramate, modafinil, 5-fluorouracil, hydrochlorothiazide, acetaminophen, aspirin, flurbiprofen, phenytoin and ibuprofen
US20040214893A1 (en) * 2003-04-11 2004-10-28 Matthew Peterson Gabapentin compositions
EP1626950A4 (en) 2003-05-23 2007-05-23 Transform Pharmaceuticals Inc SERTRALINZUSAMMENSETZUNGEN
US20050020899A1 (en) * 2003-07-25 2005-01-27 Rubicor Medical, Inc. Post-biopsy cavity treatmetn implants and methods
WO2005030182A1 (en) 2003-09-26 2005-04-07 Alza Corporation Controlled release formulations exhibiting an ascending rate of release
US8246986B2 (en) 2003-09-26 2012-08-21 Alza Corporation Drug coating providing high drug loading
MXPA06003454A (es) * 2003-09-26 2006-08-31 Johnson & Johnson Formulaciones de liberacion controlada de analgesicos opioides y no opiodes.
US20050113410A1 (en) * 2003-11-03 2005-05-26 Mark Tawa Pharmaceutical salts of zafirlukast
JP2007512359A (ja) 2003-11-19 2007-05-17 メタバシス・セラピューティクス・インコーポレイテッド 新規なリン含有甲状腺ホルモン様物質
US20060004037A1 (en) * 2004-03-25 2006-01-05 Transform Pharmaceuticals, Inc. Novel tricyclic compounds and related methods of treatment
EP1765379A4 (en) * 2004-06-17 2009-05-27 Transform Pharmaceuticals Inc PHARMACEUTICAL CO-CRYSTAL COMPOSITIONS AND RELEVANT USE METHOD
US8541026B2 (en) * 2004-09-24 2013-09-24 Abbvie Inc. Sustained release formulations of opioid and nonopioid analgesics
US8779175B2 (en) * 2004-10-25 2014-07-15 Synthonics, Inc. Coordination complexes, pharmaceutical solutions comprising coordination complexes, and methods of treating patients
US20060160783A1 (en) * 2004-12-30 2006-07-20 Transform Pharmaceuticals, Inc. Novel omeprazole forms and related methods
DE102006021016A1 (de) * 2006-05-05 2007-11-15 Dürschinger, Günter Chemisch aktivierbare Kapsel für die Durchgangsprüfung und Behandlung des Darm-Trakts
EP2037999B1 (en) 2006-07-07 2016-12-28 Proteus Digital Health, Inc. Smart parenteral administration system
US7914460B2 (en) 2006-08-15 2011-03-29 University Of Florida Research Foundation, Inc. Condensate glucose analyzer
US9114133B2 (en) 2006-08-25 2015-08-25 U.S. Dept. Of Veterans Affairs Method of improving diastolic dysfunction
PT2129654E (pt) 2007-02-09 2014-09-04 Metabasis Therapeutics Inc Antagonistas do receptor de glucagina
CN106279283A (zh) 2007-08-13 2017-01-04 症变治疗公司 新颖的葡糖激酶活化剂
US8707964B2 (en) * 2007-10-31 2014-04-29 The Invention Science Fund I, Llc Medical or veterinary digestive tract utilization systems and methods
US20090105561A1 (en) * 2007-10-17 2009-04-23 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Medical or veterinary digestive tract utilization systems and methods
US8303573B2 (en) * 2007-10-17 2012-11-06 The Invention Science Fund I, Llc Medical or veterinary digestive tract utilization systems and methods
US8789536B2 (en) * 2007-10-17 2014-07-29 The Invention Science Fund I, Llc Medical or veterinary digestive tract utilization systems and methods
US8038659B2 (en) * 2007-10-17 2011-10-18 The Invention Science Fund I, Llc Disintegrating digestive tract interaction system
US8808276B2 (en) * 2007-10-23 2014-08-19 The Invention Science Fund I, Llc Adaptive dispensation in a digestive tract
US9125979B2 (en) 2007-10-25 2015-09-08 Proteus Digital Health, Inc. Fluid transfer port information system
US8808271B2 (en) * 2007-10-31 2014-08-19 The Invention Science Fund I, Llc Medical or veterinary digestive tract utilization systems and methods
US20090163894A1 (en) * 2007-10-31 2009-06-25 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Medical or veterinary digestive tract utilization systems and methods
US8109920B2 (en) * 2007-10-31 2012-02-07 The Invention Science Fund I, Llc Medical or veterinary digestive tract utilization systems and methods
US8333754B2 (en) * 2007-10-31 2012-12-18 The Invention Science Fund I, Llc Medical or veterinary digestive tract utilization systems and methods
WO2009067463A1 (en) 2007-11-19 2009-05-28 Proteus Biomedical, Inc. Body-associated fluid transport structure evaluation devices
US20090137866A1 (en) * 2007-11-28 2009-05-28 Searete Llc, A Limited Liability Corporation Of The State Delaware Medical or veterinary digestive tract utilization systems and methods
US9226907B2 (en) 2008-02-01 2016-01-05 Abbvie Inc. Extended release hydrocodone acetaminophen and related methods and uses thereof
CN104803891B (zh) 2008-08-13 2017-10-20 症变治疗公司 胰高血糖素拮抗剂
EP2531096A4 (en) 2010-02-01 2013-09-11 Proteus Digital Health Inc DATA COLLECTION SYSTEM FOR TWO WRIST
RU2587795C2 (ru) 2010-02-01 2016-06-20 Проутьюс Диджитал Хэлс, Инк. Система сбора данных
EP2556082B1 (en) 2010-04-08 2017-02-22 Emory University Substituted androst-4-ene diones
US9585930B2 (en) 2011-03-20 2017-03-07 Trustees Of Boston University Therapeutic agent for emphysema and COPD
US20140227293A1 (en) 2011-06-30 2014-08-14 Trustees Of Boston University Method for controlling tumor growth, angiogenesis and metastasis using immunoglobulin containing and proline rich receptor-1 (igpr-1)
DK2869870T3 (da) * 2012-07-06 2019-03-11 Sanofi Aventis Deutschland Lægemiddeladministrationsanordning
CN113413537A (zh) * 2013-08-19 2021-09-21 塔里斯生物医药公司 多单元药物递送装置和方法
EP3036226B1 (en) 2013-08-22 2020-01-08 The General Hospital Corporation Inhibitors of human 12/15-lipoxygenase
EP3154956A4 (en) 2014-06-12 2018-01-17 Ligand Pharmaceuticals, Inc. Glucagon antagonists
EP3752249A1 (en) 2018-02-13 2020-12-23 Ligand Pharmaceuticals, Inc. Glucagon receptor antagonists
JP7167336B2 (ja) 2018-11-02 2022-11-08 バイオナット ラブス リミテッド 小型化されたデバイスからのペイロード放出の磁気機械的トリガー
JPWO2023181997A1 (da) * 2022-03-25 2023-09-28

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3732865A (en) 1971-01-13 1973-05-15 Alza Corp Osmotic dispenser
US3995631A (en) 1971-01-13 1976-12-07 Alza Corporation Osmotic dispenser with means for dispensing active agent responsive to osmotic gradient
US3845770A (en) 1972-06-05 1974-11-05 Alza Corp Osmatic dispensing device for releasing beneficial agent
US3995632A (en) 1973-05-04 1976-12-07 Alza Corporation Osmotic dispenser
US3916889A (en) 1973-09-28 1975-11-04 Sandoz Ag Patient ventilator apparatus
DE2626348C3 (de) * 1976-06-11 1980-01-31 Siemens Ag, 1000 Berlin Und 8000 Muenchen Implantierbare Dosiereinrichtung
US4111203A (en) 1976-11-22 1978-09-05 Alza Corporation Osmotic system with means for improving delivery kinetics of system
US4111202A (en) 1976-11-22 1978-09-05 Alza Corporation Osmotic system for the controlled and delivery of agent over time
US4203439A (en) 1976-11-22 1980-05-20 Alza Corporation Osmotic system with volume amplifier for increasing amount of agent delivered therefrom
US4243030A (en) 1978-08-18 1981-01-06 Massachusetts Institute Of Technology Implantable programmed microinfusion apparatus
US4373527B1 (en) 1979-04-27 1995-06-27 Univ Johns Hopkins Implantable programmable medication infusion system
US4340054A (en) 1980-12-29 1982-07-20 Alza Corporation Dispenser for delivering fluids and solids
US4439196A (en) 1982-03-18 1984-03-27 Merck & Co., Inc. Osmotic drug delivery system
US4457752A (en) * 1982-09-13 1984-07-03 Csaba Vadasz Surgically implantable pump
US4552561A (en) 1982-12-23 1985-11-12 Alza Corporation Body mounted pump housing and pump assembly employing the same
US4639244A (en) 1983-05-03 1987-01-27 Nabil I. Rizk Implantable electrophoretic pump for ionic drugs and associated methods
USH150H (en) 1984-08-03 1986-11-04 Medtronic, Inc. Accessory module for implantable fluid dispensing device
DE3610825A1 (de) * 1985-01-07 1987-10-08 Kurt Dr Ing Ziesche Geraet zur soforthilfe bei herzanfaellen und aehnlichem
NO165378C (no) * 1985-11-22 1991-02-06 Ellingsen O & Co Medikamentavgivende innretning for implantering i menneskekroppen.
US4865845A (en) 1986-03-21 1989-09-12 Alza Corporation Release rate adjustment of osmotic or diffusional delivery devices
JPS63300774A (ja) * 1987-05-29 1988-12-07 Kanji Takada 埋込み用薬液注入装置
US4874388A (en) 1987-06-25 1989-10-17 Alza Corporation Multi-layer delivery system
US5151093A (en) 1990-10-29 1992-09-29 Alza Corporation Osmotically driven syringe with programmable agent delivery
GB9027422D0 (en) 1990-12-18 1991-02-06 Scras Osmotically driven infusion device
US5137727A (en) 1991-06-12 1992-08-11 Alza Corporation Delivery device providing beneficial agent stability
US5223265A (en) 1992-01-10 1993-06-29 Alza Corporation Osmotic device with delayed activation of drug delivery
US5308348A (en) 1992-02-18 1994-05-03 Alza Corporation Delivery devices with pulsatile effect
US5456679A (en) 1992-02-18 1995-10-10 Alza Corporation Delivery devices with pulsatile effect
CA2150019C (en) * 1992-11-30 1999-01-05 Scott M. Herbig Supported liquid membrane delivery devices
US5421818A (en) * 1993-10-18 1995-06-06 Inner Ear Medical Delivery Systems, Inc. Multi-functional inner ear treatment and diagnostic system
SE9400821D0 (sv) * 1994-03-10 1994-03-10 Siemens Elema Ab Implanterbart infusionssystem med tryckneutral läkemedelsbehållare
EP1249229A3 (en) 1996-02-02 2005-02-02 ALZA Corporation Sustained delivery of an active agent using an implantable system
DE69730027T2 (de) * 1996-05-24 2004-11-25 Alza Corp., Mountain View Abgabevorrichtung zur Abgabe eines Farbstoffs an eine Nähstoffformulie- rung

Also Published As

Publication number Publication date
WO1999033513A1 (en) 1999-07-08
ATE322928T1 (de) 2006-04-15
ES2205595T3 (es) 2004-05-01
EP1051217B1 (en) 2003-08-27
EP1051217B8 (en) 2004-07-21
EP1051217A1 (en) 2000-11-15
ZA9811879B (en) 1999-09-02
DE69834213T2 (de) 2007-01-25
DE69817621T2 (de) 2004-03-25
ATE248002T1 (de) 2003-09-15
CA2316887A1 (en) 1999-07-08
DE69817621D1 (de) 2003-10-02
AU1937099A (en) 1999-07-19
AR014231A1 (es) 2001-02-07
HK1032363A1 (en) 2001-07-20
CA2316887C (en) 2008-04-08
PT1051217E (pt) 2003-12-31
US6283953B1 (en) 2001-09-04
DE69834213D1 (de) 2006-05-24
TW381974B (en) 2000-02-11

Similar Documents

Publication Publication Date Title
DK1051217T3 (da) System til kontrol af osmotisk medikamentlevering
DK1041975T3 (da) Hastighedskontrollerende membraner til anordninger til kontrolleret indførsel af medikament
DK0998273T3 (da) Strömningsmodulatorapparat for osmotisk afleveringssystem
EE200000546A (et) Aerosoolistatud toimeaine manustamissüsteem
BR9801027B1 (pt) sistema de distribuiÇço de medicamentos.
DE69821457D1 (de) Zusammensetzungen mit kontrollierter Wirkstoffabgabe
DE19882286T1 (de) Intravesikale Medikamentenabgabesysteme
DE69822529D1 (de) Stentanbringungssystem
ATE291417T1 (de) Gastrointestinales wirkstoffverabreichungssystem
DK1035833T3 (da) Sammensætning til nasal indgivelse
DE69711045D1 (de) Vitamin c abgabesystem
DE69840679D1 (de) Osmotisches Abgabesystem mit halbdurchlässigem Stöpsel
NO20000735L (no) Legemiddel leveringsanordning for vedvarende frigivelse
DK0998272T3 (da) Farmaceutisk præparat til kombinationen piperidinoalkanoldekongestivum
DE69635936D1 (de) Riechstofffreisetzungssystem
DE69730666D1 (de) Stentanbringungssystem
DE69731915D1 (de) Stentanbringungssystem
ID21702A (id) Sistim dispenser
NO20004196D0 (no) Innretninger for legemiddelavlevering
DK114797A (da) Farmaceutiske præparater til intranasal administrering
DE69926644D1 (de) Medikamentenzufuhrsysteme
DE69810189D1 (de) Zusammensetzungen mit kontrollierter Wirkstoffabgabe
DE69734043D1 (de) Parfümfreisetzungssystem
DE69800089D1 (de) Abgabesysteme
NL1006855A1 (nl) Sproei-installatie.