ES2196918T3 - Sistema de suministro osmotico dotado de piston con economia de espacio.. - Google Patents
Sistema de suministro osmotico dotado de piston con economia de espacio..Info
- Publication number
- ES2196918T3 ES2196918T3 ES99967575T ES99967575T ES2196918T3 ES 2196918 T3 ES2196918 T3 ES 2196918T3 ES 99967575 T ES99967575 T ES 99967575T ES 99967575 T ES99967575 T ES 99967575T ES 2196918 T3 ES2196918 T3 ES 2196918T3
- Authority
- ES
- Spain
- Prior art keywords
- piston
- osmotic
- capsule
- supply system
- system equipped
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- External Artificial Organs (AREA)
- Media Introduction/Drainage Providing Device (AREA)
Abstract
Sistema de suministro osmótico, que comprende: una cápsula, estando dotada dicha cápsula de un interior para el alojamiento de un agente beneficioso, presentando dicho interior una superficie interior; un agente osmótico situado en dicho interior; un cuerpo semipermeable en comunicación de líquido con dicha cápsula para permitir que un líquido se infiltre a través de dicho cuerpo semipermeable hasta dicho agente osmótico; y un pistón situado dentro de dicho interior de dicha cápsula, el cual puede desplazarse con respecto a dicha superficie interior de dicha cápsula, determinando una obturación móvil con dicha superficie interior de dicha cápsula que separa dicho agente osmótico de dicho agente beneficioso, y presentando un rebaje que recibe por lo menos una parte de dicho agente osmótico, dicho agente osmótico, que se encuentra situado entre dicho pistón y dicho cuerpo semipermeable, tiene por objeto embeber líquido de un ambiente envolvente a través de dicho cuerpo semipermeable para provocar que dicho pistón se desplace, produciendo a su vez una descarga del agente beneficioso de dicha cápsula.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11454898P | 1998-12-31 | 1998-12-31 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2196918T3 true ES2196918T3 (es) | 2003-12-16 |
Family
ID=22355938
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES99967575T Expired - Lifetime ES2196918T3 (es) | 1998-12-31 | 1999-12-21 | Sistema de suministro osmotico dotado de piston con economia de espacio.. |
Country Status (13)
| Country | Link |
|---|---|
| US (5) | US6544252B1 (es) |
| EP (1) | EP1140014B1 (es) |
| JP (2) | JP4383674B2 (es) |
| AT (1) | ATE234603T1 (es) |
| AU (1) | AU771132B2 (es) |
| CA (1) | CA2356860C (es) |
| DE (1) | DE69906132T2 (es) |
| DK (1) | DK1140014T3 (es) |
| ES (1) | ES2196918T3 (es) |
| HK (1) | HK1040916B (es) |
| NZ (1) | NZ512671A (es) |
| PT (1) | PT1140014E (es) |
| WO (1) | WO2000040218A2 (es) |
Families Citing this family (58)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6440457B1 (en) * | 1993-05-27 | 2002-08-27 | Alza Corporation | Method of administering antidepressant dosage form |
| MY125870A (en) * | 1997-07-25 | 2006-08-30 | Alza Corp | Osmotic delivery system flow modulator apparatus and method |
| CA2356860C (en) * | 1998-12-31 | 2006-11-07 | Alza Corporation | Osmotic delivery system having space efficient piston |
| US7258869B1 (en) | 1999-02-08 | 2007-08-21 | Alza Corporation | Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicle |
| US7919109B2 (en) | 1999-02-08 | 2011-04-05 | Intarcia Therapeutics, Inc. | Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicles |
| EP1328256B1 (en) * | 1999-12-21 | 2005-10-19 | Alza Corporation | Valve for osmotic devices |
| US7163688B2 (en) * | 2001-06-22 | 2007-01-16 | Alza Corporation | Osmotic implant with membrane and membrane retention means |
| EP1536767B1 (en) * | 2002-06-17 | 2007-08-08 | Alza Corporation | Osmotic delivery system with early zero order push power engine comprising an osmotic agent dispersed in the fluid vehicle |
| RU2342118C2 (ru) * | 2002-12-19 | 2008-12-27 | Алза Корпорейшн | Стабильные неводные однофазные гели и композиции на их основе для доставки из имплантируемого устройства |
| US7731947B2 (en) | 2003-11-17 | 2010-06-08 | Intarcia Therapeutics, Inc. | Composition and dosage form comprising an interferon particle formulation and suspending vehicle |
| EP1613389B8 (en) * | 2003-03-31 | 2008-05-07 | Intarcia Therapeutics, Inc. | Osmotic pump with means for dissipating internal pressure |
| CA2520766A1 (en) * | 2003-03-31 | 2004-10-21 | Alza Corporation | Osmotic delivery system and method for decreasing start-up times for osmotic delivery systems |
| US8257963B2 (en) | 2007-06-01 | 2012-09-04 | Depuy Mitek, Inc. | Chondrocyte container and method of use |
| KR20060121890A (ko) * | 2003-11-06 | 2006-11-29 | 알자 코포레이션 | 이식형 삼투 펌프와 함께 사용하기 위한 모듈식 흡수율감소기 |
| EP1703915A2 (en) * | 2004-01-13 | 2006-09-27 | Vasogenix Pharmaceuticals, Inc. | Methods of using cgrp for cardiovascular and renal indications |
| JP2007517913A (ja) * | 2004-01-13 | 2007-07-05 | バソジェニックス ファーマシューティカルズ, インコーポレイテッド | カルシトニン遺伝子関連ペプチドを投与することによって急性心筋梗塞を処置するための方法およびカルシトニン遺伝子関連ペプチドを含有する組成物 |
| US7976847B2 (en) * | 2004-01-13 | 2011-07-12 | Vasogenix Pharmaceuticals, Inc. | Controlled release CGRP delivery composition for cardiovascular and renal indications |
| US20050266087A1 (en) * | 2004-05-25 | 2005-12-01 | Gunjan Junnarkar | Formulations having increased stability during transition from hydrophobic vehicle to hydrophilic medium |
| EP1877077A2 (en) * | 2005-02-03 | 2008-01-16 | Intarcia Therapeutics, Inc. | An implantable interferon-containing device |
| US11246913B2 (en) | 2005-02-03 | 2022-02-15 | Intarcia Therapeutics, Inc. | Suspension formulation comprising an insulinotropic peptide |
| WO2006083761A2 (en) | 2005-02-03 | 2006-08-10 | Alza Corporation | Solvent/polymer solutions as suspension vehicles |
| US7959938B2 (en) * | 2005-03-15 | 2011-06-14 | Intarcia Therapeutics, Inc. | Polyoxaester suspending vehicles for use with implantable delivery systems |
| US20070025869A1 (en) * | 2005-07-15 | 2007-02-01 | Gordon John H | Fluid Delivery Device |
| US20070163968A1 (en) * | 2006-01-17 | 2007-07-19 | Johnsondiversey, Inc. | Method and apparatus for providing treatment chemicals to process water systems |
| MX2008014870A (es) | 2006-05-30 | 2009-02-12 | Intarcia Therapeutics Inc | Modulador de flujo para sistema de suministro osmotico con canal interno de dos piezas. |
| US8321025B2 (en) | 2006-07-31 | 2012-11-27 | Cranial Medical Systems, Inc. | Lead and methods for brain monitoring and modulation |
| US7583999B2 (en) | 2006-07-31 | 2009-09-01 | Cranial Medical Systems, Inc. | Multi-channel connector for brain stimulation system |
| MX2009001114A (es) | 2006-08-09 | 2009-02-10 | Intarcia Therapeutics Inc | Sistemas de suministro osmotico y ensambles de piston. |
| US7538652B2 (en) * | 2006-08-29 | 2009-05-26 | International Business Machines Corporation | Electrical component tuned by conductive layer deletion |
| US20080147186A1 (en) * | 2006-12-14 | 2008-06-19 | Joshi Ashok V | Electrochemical Implant For Delivering Beneficial Agents |
| CN104000779A (zh) | 2007-04-23 | 2014-08-27 | 精达制药公司 | 促胰岛素释放肽的混悬制剂及其应用 |
| CA2726861C (en) | 2008-02-13 | 2014-05-27 | Intarcia Therapeutics, Inc. | Devices, formulations, and methods for delivery of multiple beneficial agents |
| US20100092566A1 (en) * | 2008-10-15 | 2010-04-15 | Alessi Thomas R | Highly concentrated drug particles, formulations, suspensions and uses thereof |
| DK2462246T3 (da) | 2009-09-28 | 2017-11-06 | Intarcia Therapeutics Inc | Hurtig etablering og/eller afslutning af væsentlig steady-state-lægemiddelafgivelse |
| JP2011104346A (ja) * | 2009-10-22 | 2011-06-02 | Neocel:Kk | 人工透析用具 |
| CN106913902A (zh) | 2009-11-09 | 2017-07-04 | 聚光灯技术合伙有限责任公司 | 多糖基水凝胶 |
| EP2498764B1 (en) | 2009-11-09 | 2017-09-06 | Spotlight Technology Partners LLC | Fragmented hydrogels |
| AU2011296258B2 (en) | 2010-08-30 | 2015-07-09 | SinuSys Corporation | Devices for dilating a paranasal sinus opening and for treating sinusitis |
| US8583237B2 (en) | 2010-09-13 | 2013-11-12 | Cranial Medical Systems, Inc. | Devices and methods for tissue modulation and monitoring |
| US20120208755A1 (en) | 2011-02-16 | 2012-08-16 | Intarcia Therapeutics, Inc. | Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers |
| JP2015509786A (ja) | 2012-02-29 | 2015-04-02 | サイナシス コーポレーション | 副鼻腔開口部を拡張して副鼻腔炎を治療するためのデバイスおよび方法 |
| US9687263B2 (en) | 2013-05-30 | 2017-06-27 | SinuSys Corporation | Devices and methods for inserting a sinus dilator |
| US9757330B2 (en) | 2013-10-18 | 2017-09-12 | Industrial Technology Research Institute | Recipe for in-situ gel, and implant, drug delivery system formed thereby |
| US9889085B1 (en) | 2014-09-30 | 2018-02-13 | Intarcia Therapeutics, Inc. | Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c |
| US10925639B2 (en) | 2015-06-03 | 2021-02-23 | Intarcia Therapeutics, Inc. | Implant placement and removal systems |
| AU2016349381B2 (en) | 2015-11-05 | 2023-02-23 | The General Hospital Corporation | Intrathecal delivery of nucleic acid sequences encoding ABCD1 for treatment of adrenomyeloneuropathy |
| MA53353A (fr) | 2016-05-16 | 2021-06-09 | Intarcia Therapeutics Inc | Polypeptides sélectifs pour le récepteur du glucagon et méthodes pour leur utilisation |
| USD840030S1 (en) | 2016-06-02 | 2019-02-05 | Intarcia Therapeutics, Inc. | Implant placement guide |
| USD860451S1 (en) | 2016-06-02 | 2019-09-17 | Intarcia Therapeutics, Inc. | Implant removal tool |
| US10406336B2 (en) | 2016-08-03 | 2019-09-10 | Neil S. Davey | Adjustable rate drug delivery implantable device |
| SG11201903462UA (en) | 2016-10-20 | 2019-05-30 | Peptron Inc | Methods of delivering a neuroprotective polypeptide to the central nervous system |
| KR20190104039A (ko) | 2017-01-03 | 2019-09-05 | 인타르시아 세라퓨틱스 인코포레이티드 | Glp-1 수용체 효능제의 연속적인 투여 및 약물의 동시-투여를 포함하는 방법 |
| US20200188479A1 (en) | 2017-03-08 | 2020-06-18 | Intarcia Therapeutics, Inc. | Apparatus and methods for administration of a nauseogenic compound from a drug delivery device |
| CN108211107B (zh) * | 2018-03-01 | 2023-08-15 | 中南民族大学 | 一种针对穴位持续给药的压力可控式微泡贴及制备方法 |
| USD933219S1 (en) | 2018-07-13 | 2021-10-12 | Intarcia Therapeutics, Inc. | Implant removal tool and assembly |
| BR112021006823A2 (pt) | 2018-10-11 | 2021-07-27 | Intarcia Therapeutics, Inc. | polipeptídeos análogos de amilina humana e métodos de uso |
| RO134455A0 (ro) * | 2019-11-27 | 2020-09-30 | Ştefan-Sorin Aramă | Dispozitiv medical de temporizare |
| WO2025160155A1 (en) | 2024-01-22 | 2025-07-31 | The Broad Institute, Inc. | Epigenetic targeting of prion diseases |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3732865A (en) * | 1971-01-13 | 1973-05-15 | Alza Corp | Osmotic dispenser |
| US3995632A (en) * | 1973-05-04 | 1976-12-07 | Alza Corporation | Osmotic dispenser |
| US3862042A (en) * | 1974-02-27 | 1975-01-21 | Becton Dickinson Co | Serum/plasma separator - piston with red-cell trapping surfaces |
| US4074715A (en) * | 1976-11-01 | 1978-02-21 | Becton, Dickinson And Company | Syringe plunger |
| US4619652A (en) | 1982-12-23 | 1986-10-28 | Alza Corporation | Dosage form for use in a body mounted pump |
| US4595583A (en) * | 1984-03-19 | 1986-06-17 | Alza Corporation | Delivery system controlled administration of beneficial agent to ruminants |
| US4624945A (en) * | 1984-03-19 | 1986-11-25 | Alza Corporation | Dispensing system with means for increasing delivery of beneficial agent from the system |
| US4838862A (en) * | 1986-08-04 | 1989-06-13 | Pharmetrix Corp. | Portable controlled release osmotic infusion device |
| US4874388A (en) | 1987-06-25 | 1989-10-17 | Alza Corporation | Multi-layer delivery system |
| US5062841A (en) | 1988-08-12 | 1991-11-05 | The Regents Of The University Of California | Implantable, self-regulating mechanochemical insulin pump |
| US4929233A (en) * | 1988-08-26 | 1990-05-29 | Alza Corporation | Implantable fluid imbibing pump with improved closure |
| US5234424A (en) | 1988-12-28 | 1993-08-10 | Alza Corporation | Osmotically driven syringe |
| US4969884A (en) * | 1988-12-28 | 1990-11-13 | Alza Corporation | Osmotically driven syringe |
| GB9027422D0 (en) * | 1990-12-18 | 1991-02-06 | Scras | Osmotically driven infusion device |
| US5236707A (en) * | 1991-11-08 | 1993-08-17 | Dallas Biotherapeutics, Inc. | Stabilization of human interferon |
| US5221278A (en) * | 1992-03-12 | 1993-06-22 | Alza Corporation | Osmotically driven delivery device with expandable orifice for pulsatile delivery effect |
| US5639477A (en) | 1993-06-23 | 1997-06-17 | Alza Corporation | Ruminal drug delivery device |
| PL189289B1 (pl) * | 1996-02-02 | 2005-07-29 | Alza Corp | Sposób przygotowania implantowanego układu do dostarczania substancji aktywnej |
| ZA981610B (en) | 1997-03-24 | 1999-08-26 | Alza Corp | Self adjustable exit port. |
| MY125849A (en) * | 1997-07-25 | 2006-08-30 | Alza Corp | Osmotic delivery system, osmotic delivery system semipermeable body assembly, and method for controlling delivery rate of beneficial agents from osmotic delivery systems |
| WO1999033446A1 (en) * | 1997-12-29 | 1999-07-08 | Alza Corporation | Osmotic delivery system with membrane plug retention mechanism |
| DK1051217T3 (da) * | 1997-12-31 | 2003-12-08 | Eckenhoff Bonnie J | System til kontrol af osmotisk medikamentlevering |
| CA2356860C (en) * | 1998-12-31 | 2006-11-07 | Alza Corporation | Osmotic delivery system having space efficient piston |
-
1999
- 1999-12-21 CA CA002356860A patent/CA2356860C/en not_active Expired - Fee Related
- 1999-12-21 DK DK99967575T patent/DK1140014T3/da active
- 1999-12-21 HK HK02101884.5A patent/HK1040916B/en not_active IP Right Cessation
- 1999-12-21 DE DE69906132T patent/DE69906132T2/de not_active Expired - Lifetime
- 1999-12-21 AT AT99967575T patent/ATE234603T1/de active
- 1999-12-21 JP JP2000591975A patent/JP4383674B2/ja not_active Expired - Fee Related
- 1999-12-21 NZ NZ512671A patent/NZ512671A/en not_active IP Right Cessation
- 1999-12-21 EP EP99967575A patent/EP1140014B1/en not_active Expired - Lifetime
- 1999-12-21 AU AU23836/00A patent/AU771132B2/en not_active Ceased
- 1999-12-21 PT PT99967575T patent/PT1140014E/pt unknown
- 1999-12-21 WO PCT/US1999/030783 patent/WO2000040218A2/en not_active Ceased
- 1999-12-21 ES ES99967575T patent/ES2196918T3/es not_active Expired - Lifetime
- 1999-12-27 US US09/472,600 patent/US6544252B1/en not_active Expired - Lifetime
-
2003
- 2003-01-30 US US10/354,142 patent/US6872201B2/en not_active Expired - Lifetime
-
2004
- 2004-10-05 US US10/959,489 patent/US6997922B2/en not_active Expired - Lifetime
-
2006
- 2006-02-14 US US11/353,842 patent/US7235068B2/en not_active Expired - Fee Related
-
2007
- 2007-05-02 US US11/743,185 patent/US20070203476A1/en not_active Abandoned
-
2009
- 2009-04-08 JP JP2009094205A patent/JP2009183737A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| DE69906132T2 (de) | 2003-12-18 |
| ATE234603T1 (de) | 2003-04-15 |
| US20050085797A1 (en) | 2005-04-21 |
| US20070203476A1 (en) | 2007-08-30 |
| CA2356860A1 (en) | 2000-07-13 |
| NZ512671A (en) | 2003-12-19 |
| JP2009183737A (ja) | 2009-08-20 |
| PT1140014E (pt) | 2003-07-31 |
| US6872201B2 (en) | 2005-03-29 |
| CA2356860C (en) | 2006-11-07 |
| DK1140014T3 (da) | 2003-07-14 |
| JP4383674B2 (ja) | 2009-12-16 |
| JP2002534164A (ja) | 2002-10-15 |
| AU771132B2 (en) | 2004-03-11 |
| WO2000040218A2 (en) | 2000-07-13 |
| WO2000040218A3 (en) | 2000-11-09 |
| EP1140014A2 (en) | 2001-10-10 |
| HK1040916B (en) | 2003-10-03 |
| US6544252B1 (en) | 2003-04-08 |
| AU2383600A (en) | 2000-07-24 |
| US20030139732A1 (en) | 2003-07-24 |
| US7235068B2 (en) | 2007-06-26 |
| US6997922B2 (en) | 2006-02-14 |
| US20060129139A1 (en) | 2006-06-15 |
| HK1040916A1 (en) | 2002-06-28 |
| EP1140014B1 (en) | 2003-03-19 |
| DE69906132D1 (de) | 2003-04-24 |
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