DK1045691T3 - Kombinationer af statin-carboxylalkylether - Google Patents

Kombinationer af statin-carboxylalkylether

Info

Publication number: DK1045691T3
Authority: DK; Denmark
Prior art keywords: statin; combinations; alkyl ether; carboxyl alkyl; carboxyl
Prior art date: 1997-12-12

Application number

DK98960278T

Other languages

Danish (da)

English (en)

Inventor

Charles Larry Bisgaier

Roger Schofield Newton

Original Assignee

Warner Lambert Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-12-12

Filing date

1998-11-20

Publication date

2005-03-14

1998-11-20 Application filed by Warner Lambert Co filed Critical Warner Lambert Co

2005-03-14 Application granted granted Critical

2005-03-14 Publication of DK1045691T3 publication Critical patent/DK1045691T3/da

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Epidemiology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Diabetes (AREA)
Obesity (AREA)
Hematology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Steroid Compounds (AREA)

DK98960278T 1997-12-12 1998-11-20 Kombinationer af statin-carboxylalkylether DK1045691T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US6937597P	1997-12-12	1997-12-12
PCT/US1998/024679 WO1999030704A1 (fr)	1997-12-12	1998-11-20	Combinaisons de statine-carboxyalkylether

Publications (1)

Publication Number	Publication Date
DK1045691T3 true DK1045691T3 (da)	2005-03-14

Family

ID=22088573

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK98960278T DK1045691T3 (da)	1997-12-12	1998-11-20	Kombinationer af statin-carboxylalkylether

Country Status (30)

Country	Link
EP (1)	EP1045691B1 (fr)
JP (1)	JP2002508320A (fr)
KR (1)	KR20010033003A (fr)
AR (1)	AR017851A1 (fr)
AT (1)	ATE285762T1 (fr)
AU (1)	AU754089B2 (fr)
BR (1)	BR9813542A (fr)
CA (1)	CA2304612A1 (fr)
CO (1)	CO4970816A1 (fr)
CR (1)	CR5926A (fr)
CU (1)	CU20000140A7 (fr)
DE (1)	DE69828442T2 (fr)
DK (1)	DK1045691T3 (fr)
ES (1)	ES2230733T3 (fr)
GT (1)	GT199800196A (fr)
HN (1)	HN1998000185A (fr)
HU (1)	HUP0004547A3 (fr)
IL (1)	IL135349A0 (fr)
IS (1)	IS2150B (fr)
MY (1)	MY118381A (fr)
NO (1)	NO20002966L (fr)
NZ (1)	NZ503982A (fr)
PA (1)	PA8464601A1 (fr)
PE (1)	PE20000017A1 (fr)
PL (1)	PL341066A1 (fr)
PT (1)	PT1045691E (fr)
SV (1)	SV1998000146A (fr)
UY (1)	UY25299A1 (fr)
WO (1)	WO1999030704A1 (fr)
ZA (1)	ZA9811348B (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20030105154A1 (en)	2001-10-24	2003-06-05	Bisgaier Charles Larry	Statin-carboxyalkylether combinations
PL343851A1 (en) *	1997-12-12	2001-09-10	Warner Lambert Co	Antihyperlipidemic statin-lp(a) inhibitor combinations
US6861555B2 (en)	2000-01-25	2005-03-01	Warner-Lambert Company	Calcium dicarboxylate ethers, methods of making same, and treatment of vascular disease and diabetes therewith
PT1117392E (pt) *	1998-09-30	2004-07-30	Warner Lambert Co	Metodo para impedir ou atrasar a revascularizacao por cateter
US6562864B1 (en) *	1999-09-02	2003-05-13	Drake Larson	Catechin multimers as therapeutic drug delivery agents
IN191580B (fr) *	1999-12-17	2003-12-06	Ranbaxy Lab Ltd
PL357076A1 (en)	2000-01-25	2004-07-12	Warner-Lambert Company	Calcium dicarboxylate ethers, methods of making same, and treatment of vascular disease and diabetes therewith
AU2001256278A1 (en) *	2000-04-18	2001-10-30	Bayer Aktiengesellschaft	Use of cse inhibitors for treating heart failure
MXPA02009662A (es) *	2000-04-26	2003-03-10	Warner Lambert Co	Agentes antihipertensivos y su uso.
US6689807B1 (en) *	2000-06-08	2004-02-10	Caritas St. Elizabeth's Medical Center Of Boston, Inc.	HMG CoA reductase inhibitors for promoting angiogenesis
KR20040026705A (ko)	2001-08-16	2004-03-31	테바 파마슈티컬 인더스트리즈 리미티드	스타틴의 칼슘 염 형태의 제조 방법
IL160077A0 (en) *	2001-08-16	2004-06-20	Teva Pharma	Processes for preparing calcium salt forms of statins
US20050026979A1 (en) *	2003-07-31	2005-02-03	Maha Ghazzi	Methods for treating inflammation and inflammation-associated diseases with a statin and ether
AU2013207423B2 (en) *	2012-01-06	2017-10-12	Gemphire Therapeutics Inc.	Methods of reducing risk of cardiovascular disease
KR20180073597A (ko)	2015-11-06	2018-07-02	젬파이어 세러퓨틱스 인코포레이티드	혼합 이상지질혈증의 치료

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5648387A (en) *	1995-03-24	1997-07-15	Warner-Lambert Company	Carboxyalkylethers, formulations, and treatment of vascular diseases

1998
- 1998-11-12 NZ NZ503982A patent/NZ503982A/en unknown
- 1998-11-20 BR BR9813542-2A patent/BR9813542A/pt not_active Application Discontinuation
- 1998-11-20 AT AT98960278T patent/ATE285762T1/de not_active IP Right Cessation
- 1998-11-20 CA CA002304612A patent/CA2304612A1/fr not_active Abandoned
- 1998-11-20 DK DK98960278T patent/DK1045691T3/da active
- 1998-11-20 JP JP2000538687A patent/JP2002508320A/ja active Pending
- 1998-11-20 HU HU0004547A patent/HUP0004547A3/hu unknown
- 1998-11-20 ES ES98960278T patent/ES2230733T3/es not_active Expired - Lifetime
- 1998-11-20 KR KR1020007006355A patent/KR20010033003A/ko not_active Ceased
- 1998-11-20 AU AU15915/99A patent/AU754089B2/en not_active Ceased
- 1998-11-20 PL PL98341066A patent/PL341066A1/xx unknown
- 1998-11-20 PT PT98960278T patent/PT1045691E/pt unknown
- 1998-11-20 DE DE69828442T patent/DE69828442T2/de not_active Expired - Lifetime
- 1998-11-20 IL IL13534998A patent/IL135349A0/xx unknown
- 1998-11-20 EP EP98960278A patent/EP1045691B1/fr not_active Expired - Lifetime
- 1998-11-20 WO PCT/US1998/024679 patent/WO1999030704A1/fr not_active Ceased
- 1998-12-09 HN HN1998000185A patent/HN1998000185A/es unknown
- 1998-12-10 ZA ZA9811348A patent/ZA9811348B/xx unknown
- 1998-12-10 CR CR5926A patent/CR5926A/es not_active Application Discontinuation
- 1998-12-10 MY MYPI98005579A patent/MY118381A/en unknown
- 1998-12-11 PA PA19988464601A patent/PA8464601A1/es unknown
- 1998-12-11 CO CO98073828A patent/CO4970816A1/es unknown
- 1998-12-11 SV SV1998000146A patent/SV1998000146A/es not_active Application Discontinuation
- 1998-12-11 AR ARP980106321A patent/AR017851A1/es unknown
- 1998-12-11 PE PE1998001207A patent/PE20000017A1/es not_active Application Discontinuation
- 1998-12-11 GT GT199800196A patent/GT199800196A/es unknown
- 1998-12-11 UY UY25299A patent/UY25299A1/es not_active Application Discontinuation
2000
- 2000-04-14 IS IS5445A patent/IS2150B/is unknown
- 2000-06-09 CU CU20000140A patent/CU20000140A7/es unknown
- 2000-06-09 NO NO20002966A patent/NO20002966L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
NO20002966D0 (no)	2000-06-09
IL135349A0 (en)	2001-05-20
AR017851A1 (es)	2001-10-24
PT1045691E (pt)	2005-03-31
CA2304612A1 (fr)	1999-06-24
HUP0004547A3 (en)	2001-12-28
CO4970816A1 (es)	2000-11-07
HN1998000185A (es)	1999-06-02
UY25299A1 (es)	2001-08-27
PL341066A1 (en)	2001-03-26
GT199800196A (es)	2000-06-03
KR20010033003A (ko)	2001-04-25
AU1591599A (en)	1999-07-05
PA8464601A1 (es)	2001-12-14
CR5926A (es)	2000-03-06
WO1999030704A1 (fr)	1999-06-24
EP1045691B1 (fr)	2004-12-29
CU20000140A7 (es)	2005-10-19
AU754089B2 (en)	2002-11-07
DE69828442T2 (de)	2005-06-02
NO20002966L (no)	2000-06-09
ZA9811348B (en)	1999-06-14
SV1998000146A (es)	1999-09-30
PE20000017A1 (es)	2000-01-20
NZ503982A (en)	2002-03-28
MY118381A (en)	2004-10-30
IS2150B (is)	2006-10-13
HUP0004547A2 (hu)	2001-05-28
ES2230733T3 (es)	2005-05-01
EP1045691A1 (fr)	2000-10-25
ATE285762T1 (de)	2005-01-15
JP2002508320A (ja)	2002-03-19
BR9813542A (pt)	2000-10-10
DE69828442D1 (de)	2005-02-03
IS5445A (is)	2000-04-14

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