DK0891978T3 - 5H-Thiazol(3,2-a)pyrimidinderivativer - Google Patents

5H-Thiazol(3,2-a)pyrimidinderivativer

Info

Publication number: DK0891978T3
Authority: DK; Denmark
Prior art keywords: pyrimidinderivativer; thiazole
Prior art date: 1997-07-18

Application number

DK98112915T

Other languages

English (en)

Inventor

Geo Adam

Sabine Kolczewski

Vincent Mutel

Juergen Wichmann

Thomas Johannes Woltering

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-07-18

Filing date

1998-07-11

Publication date

2002-07-01

1998-07-11 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

2002-07-01 Application granted granted Critical

2002-07-01 Publication of DK0891978T3 publication Critical patent/DK0891978T3/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/20—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D239/22—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/38—One sulfur atom
- C07D239/40—One sulfur atom as doubly bound sulfur atom or as unsubstituted mercapto radical

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Hospice & Palliative Care (AREA)
Urology & Nephrology (AREA)
Heart & Thoracic Surgery (AREA)
Rheumatology (AREA)
Anesthesiology (AREA)
Ophthalmology & Optometry (AREA)
Addiction (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Cardiology (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Otolaryngology (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DK98112915T 1997-07-18 1998-07-11 5H-Thiazol(3,2-a)pyrimidinderivativer DK0891978T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP97112324		1997-07-18

Publications (1)

Publication Number	Publication Date
DK0891978T3 true DK0891978T3 (da)	2002-07-01

Family

ID=8227080

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK98112915T DK0891978T3 (da)	1997-07-18	1998-07-11	5H-Thiazol(3,2-a)pyrimidinderivativer

Country Status (32)

Country	Link
US (1)	US5958931A (da)
EP (1)	EP0891978B1 (da)
JP (1)	JP3100573B2 (da)
KR (1)	KR100296837B1 (da)
CN (1)	CN1102596C (da)
AR (1)	AR016129A1 (da)
AT (1)	ATE214704T1 (da)
AU (1)	AU738207B2 (da)
BR (1)	BR9802482A (da)
CA (1)	CA2243234C (da)
CO (1)	CO5210884A1 (da)
CZ (1)	CZ288944B6 (da)
DE (1)	DE69804273T2 (da)
DK (1)	DK0891978T3 (da)
ES (1)	ES2172840T3 (da)
HR (1)	HRP980398B1 (da)
HU (1)	HUP9801587A3 (da)
ID (1)	ID21824A (da)
IL (1)	IL125358A (da)
MA (1)	MA26520A1 (da)
NO (1)	NO310512B1 (da)
NZ (1)	NZ330988A (da)
PE (1)	PE97499A1 (da)
PL (1)	PL190218B1 (da)
PT (1)	PT891978E (da)
RU (1)	RU2197493C2 (da)
SI (1)	SI0891978T1 (da)
TR (1)	TR199801367A2 (da)
TW (1)	TW523518B (da)
UY (1)	UY25095A1 (da)
YU (1)	YU29798A (da)
ZA (1)	ZA986250B (da)

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IL157102A0 (en) *	2001-01-31	2004-02-08	Synaptic Pharma Corp	Use of gal3 receptor antagonists for the treatment of depression and/or anxiety and compounds useful in such methods
EP1408042A4 (en) *	2001-06-14	2005-02-02	Banyu Pharma Co Ltd	NEW ISOXAZOLOPYRIDONE DERIVATIVES AND THEIR USE
US7329662B2 (en) *	2003-10-03	2008-02-12	Hoffmann-La Roche Inc.	Pyrazolo-pyridine
MXPA06014809A (es) *	2004-06-21	2007-02-12	Hoffmann La Roche	Derivados de pirazol-pirimidina.
KR100847160B1 (ko) *	2004-06-21	2008-07-17	에프. 호프만-라 로슈 아게	피라졸로 피리미딘 유도체
JP4708438B2 (ja)	2005-02-11	2011-06-22	エフ．ホフマン−ラロシュアーゲー	ｍＧｌｕＲ２アンタゴニストとしてのピラゾロピリミジン誘導体
AU2006226669B2 (en)	2005-03-23	2011-12-08	F. Hoffmann-La Roche Ag	Acetylenyl-pyrazolo-pvrimidine derivatives as mGluR2 antagonists
AR053347A1 (es) *	2005-04-06	2007-05-02	Astrazeneca Ab	Derivados de [1,3]tiazolo[4,5-d]pirimidin-2(3h)-ona 5,7-sustituidos
UA90707C2 (en) *	2005-04-06	2010-05-25	Астразенека Аб	Novel 5-substituted 7-amino-[1,3]thiazolo[4,5-d]pyrimidine derivatives
AU2006298829B2 (en)	2005-09-27	2011-03-03	F. Hoffmann-La Roche Ag	Oxadiazolyl pyrazolo-pyrimidines as mGluR2 antagonists
AR059898A1 (es) *	2006-03-15	2008-05-07	Janssen Pharmaceutica Nv	Derivados de 3-ciano-piridona 1,4-disustituida y su uso como moduladores alostericos de los receptores mglur2
TW200900065A (en)	2007-03-07	2009-01-01	Janssen Pharmaceutica Nv	3-cyano-4-(4-pyridinyloxy-phenyl)-pyridin-2-one derivatives
TW200845978A (en) *	2007-03-07	2008-12-01	Janssen Pharmaceutica Nv	3-cyano-4-(4-tetrahydropyran-phenyl)-pyridin-2-one derivatives
HRP20110278T1 (hr)	2007-09-14	2011-05-31	Ortho-Mcneil-Janssen Pharmaceuticals	1',3'-disupstituirani-4-fenil,3,4,5,6-tetrahidro-2h,1'h[1,4']bipiridinil-2'-oni
TW200927731A (en) *	2007-09-14	2009-07-01	Ortho Mcneil Janssen Pharm	1,3-disubstituted-4-phenyl-1H-pyridin-2-ones
NZ584152A (en)	2007-09-14	2011-11-25	Ortho Mcneil Janssen Pharm	1,3-disubstituted 4-(aryl-x-phenyl)-1h-pyridin-2-ones
ES2637794T3 (es) *	2007-11-14	2017-10-17	Janssen Pharmaceuticals, Inc.	Derivados de imidazo[1,2-A]piridina y su uso como moduladores alostéricos positivos de receptores MGLUR2
JP5547194B2 (ja)	2008-09-02	2014-07-09	ジャンセンファーマシューティカルズ，インコーポレイテッド．	代謝型グルタミン酸受容体の調節因子としての３−アザビシクロ［３．１．０］ヘキシル誘導体
MX2011003691A (es)	2008-10-16	2011-09-06	Ortho Mcneil Janssen Pharm	Derivados de indol y benzomorfolina como moduladores de los receptores de glutamato metabotropico.
CN102232074B (zh)	2008-11-28	2014-12-03	奥梅-杨森制药有限公司	作为代谢性谷氨酸盐受体调节剂的吲哚和苯并噁嗪衍生物
CN101503414B (zh) *	2009-03-04	2013-10-30	沈阳药科大学	噻唑并[3,2-b]-1,2,4-三嗪衍生物及其应用
CN102439008B (zh)	2009-05-12	2015-04-29	杨森制药有限公司	1,2,4-三唑并[4,3-a]吡啶衍生物及其用于治疗或预防神经和精神病症的用途
CA2760259C (en)	2009-05-12	2018-05-01	Janssen Pharmaceuticals, Inc.	1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors
MY153913A (en)	2009-05-12	2015-04-15	Janssen Pharmaceuticals Inc	7-aryl-1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors
CA2814996C (en)	2010-11-08	2019-10-01	Janssen Pharmaceuticals, Inc.	1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors
CA2815002C (en)	2010-11-08	2019-10-22	Janssen Pharmaceuticals, Inc.	1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors
CN103261195B (zh)	2010-11-08	2015-09-02	杨森制药公司	1,2,4-三唑并[4,3-a]吡啶衍生物及其作为MGLUR2受体的正变构调节剂的用途
JO3368B1 (ar)	2013-06-04	2019-03-13	Janssen Pharmaceutica Nv	مركبات 6، 7- ثاني هيدرو بيرازولو [5،1-a] بيرازين- 4 (5 يد)- اون واستخدامها بصفة منظمات تفارغية سلبية لمستقبلات ميجلور 2
JO3367B1 (ar)	2013-09-06	2019-03-13	Janssen Pharmaceutica Nv	مركبات 2،1، 4- ثلاثي زولو [3،4-a] بيريدين واستخدامها بصفة منظمات تفارغية موجبة لمستقبلات ميجلور 2
PL3055315T3 (pl)	2013-10-11	2018-12-31	F. Hoffmann-La Roche Ag	Tiazolopirymidynony jako modulatory aktywności receptora nmda
KR20200036063A (ko)	2014-01-21	2020-04-06	얀센 파마슈티카 엔.브이.	대사 조절형 글루탐산 작동성 수용체 제2아형의 양성 알로스테릭 조절제 또는 오르토스테릭 작동제를 포함하는 조합 및 그 용도
EP3096790B1 (en)	2014-01-21	2019-07-10	Janssen Pharmaceutica, N.V.	Combinations comprising positive allosteric modulators or orthosteric agonists of metabotropic glutamatergic receptor subtype 2 and their use
CN116076518A (zh) *	2017-03-31	2023-05-09	巴斯夫欧洲公司	用于防除动物害虫的嘧啶鎓化合物及其混合物

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GB1582744A (en) *	1976-06-04	1981-01-14	Gruenenthal Gmbh	7h-thiazolo (and 1,3,4-thiadiazolo-)(3,2-a) pyrimidin-7-one-5-carboxylic acids derivatives and medicaments therof
SU1169330A1 (ru) *	1983-11-10	1995-11-27	Институт Тонкой Органической Химии Им.А.Л.Мнджояна	Способ получения 4-п-алкоксифенил-2,6-диоксогексагидропиримидинов
HUT42077A (en) *	1985-06-03	1987-06-29	Squibb & Sons Inc	Process for producing diesters of 2-tioxo- or 2-oxo-pyrimidine-1,5-dicarboxylic acid and 1-acyl-pyrimidine-5-carboxylic acids and esters
DD296492A5 (de) *	1989-06-13	1991-12-05	��@��@�K@��k��	Pyrrolo-[2,1-b]-thiazol-derivate und verfahren zu deren herstellung
EP0524055A1 (fr) *	1991-07-19	1993-01-20	Synthelabo	Dérivés d'imidazo[2,1-b]benzothiazole-3-acétamide, leur préparation et leur application en thérapeutique
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GB9609976D0 (en) *	1996-05-13	1996-07-17	Lilly Industries Ltd	Pharmaceutical compounds
AU3783497A (en) *	1996-08-09	1998-03-06	Yamanouchi Pharmaceutical Co., Ltd.	Metabotropic glutamate receptor agonists

1998
- 1998-07-11 PT PT98112915T patent/PT891978E/pt unknown
- 1998-07-11 EP EP98112915A patent/EP0891978B1/en not_active Expired - Lifetime
- 1998-07-11 DE DE69804273T patent/DE69804273T2/de not_active Expired - Fee Related
- 1998-07-11 ES ES98112915T patent/ES2172840T3/es not_active Expired - Lifetime
- 1998-07-11 AT AT98112915T patent/ATE214704T1/de not_active IP Right Cessation
- 1998-07-11 SI SI9830130T patent/SI0891978T1/xx unknown
- 1998-07-11 DK DK98112915T patent/DK0891978T3/da active
- 1998-07-14 NO NO19983244A patent/NO310512B1/no not_active IP Right Cessation
- 1998-07-14 ZA ZA986250A patent/ZA986250B/xx unknown
- 1998-07-14 NZ NZ330988A patent/NZ330988A/xx unknown
- 1998-07-14 TR TR1998/01367A patent/TR199801367A2/xx unknown
- 1998-07-14 US US09/115,191 patent/US5958931A/en not_active Expired - Fee Related
- 1998-07-14 MA MA25167A patent/MA26520A1/fr unknown
- 1998-07-14 ID IDP981000A patent/ID21824A/id unknown
- 1998-07-15 IL IL12535898A patent/IL125358A/en not_active IP Right Cessation
- 1998-07-15 CN CN98116063A patent/CN1102596C/zh not_active Expired - Fee Related
- 1998-07-15 YU YU29798A patent/YU29798A/sh unknown
- 1998-07-15 CA CA002243234A patent/CA2243234C/en not_active Expired - Fee Related
- 1998-07-15 JP JP10199363A patent/JP3100573B2/ja not_active Expired - Fee Related
- 1998-07-15 HU HU9801587A patent/HUP9801587A3/hu unknown
- 1998-07-15 PE PE1998000625A patent/PE97499A1/es not_active Application Discontinuation
- 1998-07-16 AR ARP980103469A patent/AR016129A1/es not_active Application Discontinuation
- 1998-07-16 PL PL98327532A patent/PL190218B1/pl unknown
- 1998-07-16 CO CO98040510A patent/CO5210884A1/es not_active Application Discontinuation
- 1998-07-16 CZ CZ19982239A patent/CZ288944B6/cs not_active IP Right Cessation
- 1998-07-16 KR KR1019980028788A patent/KR100296837B1/ko not_active Expired - Fee Related
- 1998-07-16 HR HR980398A patent/HRP980398B1/xx not_active IP Right Cessation
- 1998-07-16 BR BR9802482-5A patent/BR9802482A/pt not_active Application Discontinuation
- 1998-07-16 UY UY25095A patent/UY25095A1/es unknown
- 1998-07-17 AU AU77302/98A patent/AU738207B2/en not_active Ceased
- 1998-07-17 RU RU98114683/04A patent/RU2197493C2/ru not_active IP Right Cessation
- 1998-07-21 TW TW087111834A patent/TW523518B/zh not_active IP Right Cessation

Also Published As

Publication number	Publication date
EP0891978B1 (en)	2002-03-20
MA26520A1 (fr)	2004-12-20
CN1206010A (zh)	1999-01-27
EP0891978A3 (en)	1999-02-03
CN1102596C (zh)	2003-03-05
ZA986250B (en)	1999-01-22
CO5210884A1 (es)	2002-10-30
PL327532A1 (en)	1999-02-01
PL190218B1 (pl)	2005-11-30
HRP980398B1 (en)	2002-06-30
EP0891978A2 (en)	1999-01-20
RU2197493C2 (ru)	2003-01-27
AU738207B2 (en)	2001-09-13
NO983244D0 (no)	1998-07-14
TR199801367A3 (tr)	1999-02-22
TW523518B (en)	2003-03-11
ID21824A (id)	1999-07-29
AR016129A1 (es)	2001-06-20
HUP9801587A2 (hu)	1999-11-29
NO310512B1 (no)	2001-07-16
BR9802482A (pt)	2000-03-14
DE69804273D1 (de)	2002-04-25
HUP9801587A3 (en)	2001-09-28
IL125358A (en)	2002-09-12
ATE214704T1 (de)	2002-04-15
CA2243234C (en)	2007-09-18
YU29798A (sh)	2001-12-26
CZ288944B6 (cs)	2001-10-17
DE69804273T2 (de)	2002-10-31
SI0891978T1 (en)	2002-06-30
NZ330988A (en)	1999-03-29
IL125358A0 (en)	1999-03-12
UY25095A1 (es)	2001-01-31
ES2172840T3 (es)	2002-10-01
PT891978E (pt)	2002-07-31
PE97499A1 (es)	1999-10-12
CA2243234A1 (en)	1999-01-18
TR199801367A2 (xx)	1999-02-22
HU9801587D0 (en)	1998-09-28
HRP980398A2 (en)	1999-04-30
KR100296837B1 (ko)	2001-10-26
US5958931A (en)	1999-09-28
CZ223998A3 (cs)	1999-02-17
AU7730298A (en)	1999-01-28
HK1018439A1 (en)	1999-12-24
JP3100573B2 (ja)	2000-10-16
KR19990013919A (ko)	1999-02-25
JPH1171380A (ja)	1999-03-16
NO983244L (no)	1999-01-19

Publication	Publication Date	Title
DK0891978T3 (da)	2002-07-01	5H-Thiazol(3,2-a)pyrimidinderivativer
NO2006016I1 (no)	2006-11-27	7,8,9,10-tetrahydro-6H-6,10-metanoazepinoÄ4,5-gÜkinoksalintartrat
PT993456E (pt)	2005-01-31	4,5-diaril-imidazoles 2-substituidos
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ID21413A (id)	1999-06-10	Turunan-turunan 1,3,8,-triaza-spiro (4,5) dekan-4-on
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