DK0782565T3 - Ioderede røntgenstrålekontrastmidler - Google Patents
Ioderede røntgenstrålekontrastmidlerInfo
- Publication number
- DK0782565T3 DK0782565T3 DK95932108T DK95932108T DK0782565T3 DK 0782565 T3 DK0782565 T3 DK 0782565T3 DK 95932108 T DK95932108 T DK 95932108T DK 95932108 T DK95932108 T DK 95932108T DK 0782565 T3 DK0782565 T3 DK 0782565T3
- Authority
- DK
- Denmark
- Prior art keywords
- group
- groups
- moiety
- contrast agents
- ray contrast
- Prior art date
Links
- 239000002872 contrast media Substances 0.000 title abstract 2
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical group [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000005708 carbonyloxy group Chemical group [*:2]OC([*:1])=O 0.000 abstract 1
- 229910052740 iodine Inorganic materials 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
- C07C237/46—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having carbon atoms of carboxamide groups, amino groups and at least three atoms of bromine or iodine, bound to carbon atoms of the same non-condensed six-membered aromatic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
- A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
- C07C233/24—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
- C07C233/25—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C235/16—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C275/42—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by carboxyl groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Analysing Materials By The Use Of Radiation (AREA)
- Exposure And Positioning Against Photoresist Photosensitive Materials (AREA)
- Liquid Crystal (AREA)
- Electrochromic Elements, Electrophoresis, Or Variable Reflection Or Absorption Elements (AREA)
- Devices For Indicating Variable Information By Combining Individual Elements (AREA)
- Silver Salt Photography Or Processing Solution Therefor (AREA)
- Apparatus For Radiation Diagnosis (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9419206A GB9419206D0 (en) | 1994-09-23 | 1994-09-23 | Contrast media |
| PCT/GB1995/002264 WO1996009285A1 (fr) | 1994-09-23 | 1995-09-22 | Agents de contraste iodes pour radiographie |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0782565T3 true DK0782565T3 (da) | 1999-10-18 |
Family
ID=10761799
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK95932108T DK0782565T3 (da) | 1994-09-23 | 1995-09-22 | Ioderede røntgenstrålekontrastmidler |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US5958375A (fr) |
| EP (1) | EP0782565B1 (fr) |
| JP (1) | JP3606583B2 (fr) |
| AT (1) | ATE178592T1 (fr) |
| AU (1) | AU710934B2 (fr) |
| CA (1) | CA2200752A1 (fr) |
| CZ (1) | CZ89497A3 (fr) |
| DE (2) | DE69508949T4 (fr) |
| DK (1) | DK0782565T3 (fr) |
| EE (1) | EE9700054A (fr) |
| ES (1) | ES2130650T3 (fr) |
| FI (1) | FI971200A7 (fr) |
| GB (1) | GB9419206D0 (fr) |
| GR (1) | GR3030425T3 (fr) |
| HU (1) | HUT77170A (fr) |
| MX (1) | MX9702088A (fr) |
| NO (1) | NO971318L (fr) |
| NZ (1) | NZ292974A (fr) |
| PL (1) | PL319367A1 (fr) |
| SK (1) | SK35597A3 (fr) |
| WO (1) | WO1996009285A1 (fr) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9419203D0 (en) * | 1994-09-23 | 1994-11-09 | Nycomed Innovation Ab | Contrast media |
| GB9710726D0 (en) * | 1997-05-23 | 1997-07-16 | Nycomed Imaging As | Compound |
| DE60020960T2 (de) * | 1999-04-30 | 2006-05-24 | Amersham Health As | Kontrastmittel |
| DK1372551T3 (da) | 2001-03-08 | 2009-01-12 | Univ Pennsylvania | Faciale amphifile polymerer som anti-infektionsmidler |
| US9241917B2 (en) | 2003-03-17 | 2016-01-26 | The Trustees Of The University Of Pennsylvania | Facially amphiphilic polymers and oligomers and uses thereof |
| JP2011500770A (ja) * | 2007-10-30 | 2011-01-06 | ジーイー・ヘルスケア・アクスイェ・セルスカプ | 造影剤 |
| US8445725B2 (en) * | 2008-01-14 | 2013-05-21 | Mallinckrodt Llc | Process for the preparation of iosimenol |
| JP5164755B2 (ja) * | 2008-09-09 | 2013-03-21 | キヤノン株式会社 | ビス−アセチルアミノフェニル化合物の結晶の製造方法 |
| WO2012136813A2 (fr) | 2011-04-07 | 2012-10-11 | Universitetet I Oslo | Agents pour un diagnostic par radar médical |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2776241A (en) * | 1952-08-06 | 1957-01-01 | Schering Ag | Injectable x-ray contrast agents comprising salts of n-acyl derivatives of 2, 4, 6-triiodo-3-aminobenzoic acid |
| US2708678A (en) * | 1954-01-15 | 1955-05-17 | Schering Corp | Iodinated acyl derivatives of 2, 4, 6-trhodometa-aminobenzoic acid |
| GB1033777A (en) * | 1963-06-06 | 1966-06-22 | Sterling Drug Inc | Bis-anilide derivatives |
| US3794729A (en) * | 1971-07-16 | 1974-02-26 | Schering Corp | Inhibiting blood platelet aggregation |
| CH576255A5 (fr) * | 1972-11-17 | 1976-06-15 | Bracco Ind Chimica Spa | |
| DE2737802A1 (de) * | 1977-08-22 | 1979-03-08 | Henning Berlin Gmbh | Arzneimittel oder diagnostikum zur behandlung oder feststellung von schilddruesenfunktionsstoerungen und verfahren zu dessen herstellung |
| DE3037858A1 (de) * | 1980-10-07 | 1982-05-19 | Boehringer Mannheim Gmbh, 6800 Mannheim | Verfahren zur herstellung von reaktiven, kupplungsfaehigen derivaten der schilddruesenhormone t (pfeil abwaerts)3(pfeil abwaerts) und t (pfeil abwaerts)4(pfeil abwaerts) und deren verwendung |
| IL86450A (en) * | 1987-05-22 | 1994-05-30 | Bracco Int Bv | Process for making a history of 5-acylamino-2,4,6-triiodo and tribromo-benzoic acid, and some such new compounds |
| GB8906130D0 (en) * | 1989-03-17 | 1989-05-04 | Nycomed As | Compositions |
| US5075502A (en) * | 1989-12-13 | 1991-12-24 | Mallinckrodt, Inc. | Nonionic x-ray contrast agents, compositions and methods |
| GB9020091D0 (en) * | 1990-09-14 | 1990-10-24 | Nycomed As | Contrast media |
| FR2673180B1 (fr) * | 1991-02-25 | 1994-03-04 | Guerbet Sa | Nouveaux composes non ioniques poly-iodes, procede de preparation, produit de contraste les contenant. |
| FR2695125B1 (fr) * | 1992-08-25 | 1994-12-23 | Guerbet Sa | Nouveaux composés poly-iodés, procédé de préparation, produit de contraste les contenant. |
| NZ250063A (en) * | 1992-12-14 | 1996-03-26 | Eastman Kodak Co | Iodinated aromatic acid ester derivatives; x-ray contrast compositions |
| IT1256248B (it) * | 1992-12-24 | 1995-11-29 | Bracco Spa | Formulazioni iniettabili acquose per radiodiagnostica comprendenti miscele di composti aromatici iodurati utili come agenti opacizzanti ai raggi x |
-
1994
- 1994-09-23 GB GB9419206A patent/GB9419206D0/en active Pending
-
1995
- 1995-06-06 US US08/470,043 patent/US5958375A/en not_active Expired - Fee Related
- 1995-09-22 FI FI971200A patent/FI971200A7/fi unknown
- 1995-09-22 CA CA002200752A patent/CA2200752A1/fr not_active Abandoned
- 1995-09-22 US US08/793,927 patent/US5958376A/en not_active Expired - Fee Related
- 1995-09-22 EE EE9700054A patent/EE9700054A/xx unknown
- 1995-09-22 ES ES95932108T patent/ES2130650T3/es not_active Expired - Lifetime
- 1995-09-22 JP JP51070596A patent/JP3606583B2/ja not_active Expired - Fee Related
- 1995-09-22 SK SK355-97A patent/SK35597A3/sk unknown
- 1995-09-22 HU HU9701947A patent/HUT77170A/hu unknown
- 1995-09-22 AU AU35293/95A patent/AU710934B2/en not_active Ceased
- 1995-09-22 DE DE69508949T patent/DE69508949T4/de not_active Expired - Lifetime
- 1995-09-22 CZ CZ97894A patent/CZ89497A3/cs unknown
- 1995-09-22 DK DK95932108T patent/DK0782565T3/da active
- 1995-09-22 DE DE69508949A patent/DE69508949D1/de not_active Expired - Lifetime
- 1995-09-22 WO PCT/GB1995/002264 patent/WO1996009285A1/fr not_active Ceased
- 1995-09-22 EP EP95932108A patent/EP0782565B1/fr not_active Expired - Lifetime
- 1995-09-22 PL PL95319367A patent/PL319367A1/xx unknown
- 1995-09-22 AT AT95932108T patent/ATE178592T1/de not_active IP Right Cessation
- 1995-09-22 MX MX9702088A patent/MX9702088A/es unknown
- 1995-09-23 NZ NZ292974A patent/NZ292974A/xx unknown
-
1997
- 1997-03-20 NO NO971318A patent/NO971318L/no not_active Application Discontinuation
-
1999
- 1999-06-03 GR GR990401509T patent/GR3030425T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0782565A1 (fr) | 1997-07-09 |
| EE9700054A (et) | 1997-08-15 |
| GR3030425T3 (en) | 1999-09-30 |
| ATE178592T1 (de) | 1999-04-15 |
| EP0782565B1 (fr) | 1999-04-07 |
| CZ89497A3 (en) | 1997-09-17 |
| MX9702088A (es) | 1997-06-28 |
| AU710934B2 (en) | 1999-09-30 |
| ES2130650T3 (es) | 1999-07-01 |
| GB9419206D0 (en) | 1994-11-09 |
| JPH10505856A (ja) | 1998-06-09 |
| FI971200A0 (fi) | 1997-03-21 |
| SK35597A3 (en) | 1997-11-05 |
| FI971200L (fi) | 1997-05-19 |
| DE69508949D1 (de) | 1999-05-12 |
| US5958375A (en) | 1999-09-28 |
| NO971318L (no) | 1997-08-11 |
| WO1996009285A1 (fr) | 1996-03-28 |
| NZ292974A (en) | 1999-03-29 |
| DE69508949T2 (de) | 1999-09-09 |
| HUT77170A (hu) | 1998-03-02 |
| NO971318D0 (no) | 1997-03-20 |
| AU3529395A (en) | 1996-04-09 |
| US5958376A (en) | 1999-09-28 |
| PL319367A1 (en) | 1997-08-04 |
| CA2200752A1 (fr) | 1996-03-28 |
| FI971200A7 (fi) | 1997-05-19 |
| JP3606583B2 (ja) | 2005-01-05 |
| DE69508949T4 (de) | 1999-12-09 |
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