DK0632028T3 - Optisk aktivt 2-nitroimidazolderivat, fremgangsmåde til fremstilling af samme og mellemprodukt til fremstilling af samme - Google Patents

Optisk aktivt 2-nitroimidazolderivat, fremgangsmåde til fremstilling af samme og mellemprodukt til fremstilling af samme

Info

Publication number: DK0632028T3
Authority: DK; Denmark
Prior art keywords: same; optically active; preparation; nitroimidazole derivative; producing
Prior art date: 1992-12-18

Application number

DK93923039T

Other languages

Danish (da)

English (en)

Inventor

Toshimitsu Suzuki

Azuma Pola Pharm R D La Nishio

Original Assignee

Pola Chem Ind Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-12-18

Filing date

1993-10-21

Publication date

2003-07-21

1993-10-21 Application filed by Pola Chem Ind Inc filed Critical Pola Chem Ind Inc

2003-07-21 Application granted granted Critical

2003-07-21 Publication of DK0632028T3 publication Critical patent/DK0632028T3/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/62—Halogen-containing esters
- C07C69/63—Halogen-containing esters of saturated acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
- C07C69/78—Benzoic acid esters
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/91—Nitro radicals

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

DK93923039T 1992-12-18 1993-10-21 Optisk aktivt 2-nitroimidazolderivat, fremgangsmåde til fremstilling af samme og mellemprodukt til fremstilling af samme DK0632028T3 (da)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
JP33903592		1992-12-18
JP1653093		1993-02-03
PCT/JP1993/001519 WO1994014778A1 (fr)	1992-12-18	1993-10-21	Derive optiquement actif de 2-nitroimidazole, son procede de production, et intermediaire pour sa production

Publications (1)

Publication Number	Publication Date
DK0632028T3 true DK0632028T3 (da)	2003-07-21

Family

ID=26352886

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK93923039T DK0632028T3 (da)	1992-12-18	1993-10-21	Optisk aktivt 2-nitroimidazolderivat, fremgangsmåde til fremstilling af samme og mellemprodukt til fremstilling af samme

Country Status (9)

Country	Link
US (1)	US5532380A (fr)
EP (1)	EP0632028B1 (fr)
JP (2)	JP3577079B2 (fr)
AT (1)	ATE236131T1 (fr)
DE (1)	DE69332821T2 (fr)
DK (1)	DK0632028T3 (fr)
ES (1)	ES2199221T3 (fr)
PT (1)	PT632028E (fr)
WO (1)	WO1994014778A1 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1838305A1 (fr) *	2005-01-21	2007-10-03	Richard H. Matthews	Formulations radiosensibilisantes comprenant des derives de nitrohistidine
EP2116241B1 (fr) *	2007-01-26	2016-04-27	Pola Pharma Inc.	Composition pharmaceutique
CN101541324B (zh)	2007-06-14	2011-06-15	株式会社宝丽制药	医药组合物
CN101642452B (zh) *	2008-08-06	2014-05-28	株式会社宝丽制药	脑肿瘤用放射线敏化剂
CN101805323B (zh) *	2010-03-23	2012-09-26	深圳万乐药业有限公司	一种合成Doranidazole中间体的非对映异构体的方法
JP6071715B2 (ja) *	2013-03-22	2017-02-01	株式会社ポーラファルマ	ドラニダゾール構成光学異性体の製造方法
EP3692990A4 (fr)	2017-10-02	2021-06-30	Keio University	Inhibiteur des cellules souches cancéreuses

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2314454A (en) *	1938-08-19	1943-03-23	Gen Aniline & Film Corp	Production of esters of halogen alcohols
US2377878A (en) *	1941-12-24	1945-06-12	Du Pont	Dioxolane-acid halide reaction and product
US2901506A (en) *	1956-12-06	1959-08-25	American Cyanamid Co	Pyrolysis of substituted carbonyloxyalkyl halides
NL292912A (fr) *	1962-05-18
US3468902A (en) *	1966-06-10	1969-09-23	Hoffmann La Roche	1-substituted-2-nitroimidazole derivatives
CH526506A (de) *	1970-05-27	1972-08-15	Sandoz Ag	Verfahren zur Herstellung von 2,2-Bis-(brommethyl)-propandiol-1,3-diacetat
ZW8781A1 (en) *	1980-05-23	1981-12-16	Hoffmann La Roche	2-nitroimidazoles and preparation thereof
US4462992A (en) *	1982-02-08	1984-07-31	Research Corporation	Nitroimidazole radiosensitizers for hypoxic tumor cells and compositions thereof
JPS58170725A (ja) *	1982-03-31	1983-10-07	Ono Pharmaceut Co Ltd	グリセリン誘導体
JPS59139363A (ja) *	1983-01-31	1984-08-10	Kayaku:Kk	２−ニトロイミダゾ−ル誘導体およびその製造法
JPS62283943A (ja) *	1986-05-30	1987-12-09	Taisho Pharmaceut Co Ltd	スレイト−ル化合物およびその製造方法
JPS6330491A (ja) *	1986-07-22	1988-02-09	Sankyo Co Ltd	環状ウレタン構造を有する燐酸エステル誘導体
JPH0819111B2 (ja) *	1987-10-22	1996-02-28	ポーラ化成工業株式会社	２―ニトロイミダゾール誘導体及びこれを有効成分とする放射線増感剤
KR927003539A (ko) *	1990-01-26	1992-12-18	스즈끼 쯔네시	2-니트로 이미다졸 유도체, 그의 제조방법 및 이를 유효성분으로 하는 방사선 증감제
JP2683613B2 (ja) *	1990-01-30	1997-12-03	出光石油化学株式会社	スチレン系樹脂から成る射出成形品

1993
- 1993-10-21 EP EP93923039A patent/EP0632028B1/fr not_active Expired - Lifetime
- 1993-10-21 ES ES93923039T patent/ES2199221T3/es not_active Expired - Lifetime
- 1993-10-21 PT PT93923039T patent/PT632028E/pt unknown
- 1993-10-21 WO PCT/JP1993/001519 patent/WO1994014778A1/fr not_active Ceased
- 1993-10-21 US US08/256,354 patent/US5532380A/en not_active Expired - Lifetime
- 1993-10-21 DK DK93923039T patent/DK0632028T3/da active
- 1993-10-21 DE DE69332821T patent/DE69332821T2/de not_active Expired - Lifetime
- 1993-10-21 JP JP51458594A patent/JP3577079B2/ja not_active Expired - Lifetime
- 1993-10-21 AT AT93923039T patent/ATE236131T1/de active
2003
- 2003-05-29 JP JP2003152888A patent/JP2003321459A/ja active Pending

Also Published As

Publication number	Publication date
JP3577079B2 (ja)	2004-10-13
WO1994014778A1 (fr)	1994-07-07
EP0632028B1 (fr)	2003-04-02
EP0632028A4 (fr)	1995-03-29
EP0632028A1 (fr)	1995-01-04
DE69332821T2 (de)	2003-11-13
PT632028E (pt)	2003-08-29
ES2199221T3 (es)	2004-02-16
US5532380A (en)	1996-07-02
JP2003321459A (ja)	2003-11-11
DE69332821D1 (de)	2003-05-08
ATE236131T1 (de)	2003-04-15

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