DK0688786T3 - Hydrazino- og hydroxyamino-14beta-hydroxyandrostanderivater med aktivitet på det cardiovaskulære system, fremgangsmåder til deres fremstilling og farmaceutiske præparater indeholdende disse. - Google Patents

Hydrazino- og hydroxyamino-14beta-hydroxyandrostanderivater med aktivitet på det cardiovaskulære system, fremgangsmåder til deres fremstilling og farmaceutiske præparater indeholdende disse.

Info

Publication number: DK0688786T3
Authority: DK; Denmark
Prior art keywords: hydroxyamino; hydrazino; preparation; derivatives; 14beta
Prior art date: 1994-06-13

Application number

DK95108257.7T

Other languages

English (en)

Inventor

Piero Melloni

Alberto Cerri

Patrizia Ferrari

Giuseppe Bianchi

Elena Folpini

Original Assignee

Sigma Tau Ind Farmaceuti

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-06-13

Filing date

1995-05-30

Publication date

1997-09-15

1995-05-30 Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti

1997-09-15 Application granted granted Critical

1997-09-15 Publication of DK0688786T3 publication Critical patent/DK0688786T3/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0038—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 with an androstane skeleton, including 18- or 19-substituted derivatives, 18-nor derivatives and also derivatives where position 17-beta is substituted by a carbon atom not directly bonded to a further carbon atom and not being part of an amide group
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of only two carbon atoms, e.g. pregnane derivatives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0055—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Steroid Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

DK95108257.7T 1994-06-13 1995-05-30 Hydrazino- og hydroxyamino-14beta-hydroxyandrostanderivater med aktivitet på det cardiovaskulære system, fremgangsmåder til deres fremstilling og farmaceutiske præparater indeholdende disse. DK0688786T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE4420501A DE4420501A1 (de)	1994-06-13	1994-06-13	Neue Hydrazino- und Hydroxyamino-14beta-hydroxyandrostanderivate mit Aktivität für das cardiovaskuläre System, Verfahren zu deren Herstellung und pharmazeutische Zusammensetzungen, die diese enthalten

Publications (1)

Publication Number	Publication Date
DK0688786T3 true DK0688786T3 (da)	1997-09-15

Family

ID=6520395

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK95108257.7T DK0688786T3 (da)	1994-06-13	1995-05-30	Hydrazino- og hydroxyamino-14beta-hydroxyandrostanderivater med aktivitet på det cardiovaskulære system, fremgangsmåder til deres fremstilling og farmaceutiske præparater indeholdende disse.

Country Status (12)

Country	Link
US (1)	US5599806A (da)
EP (1)	EP0688786B1 (da)
JP (1)	JP3805406B2 (da)
KR (1)	KR100305739B1 (da)
AT (1)	ATE156490T1 (da)
CA (1)	CA2151561C (da)
DE (2)	DE4420501A1 (da)
DK (1)	DK0688786T3 (da)
ES (1)	ES2105815T3 (da)
GR (1)	GR3025064T3 (da)
TW (1)	TW293823B (da)
ZA (1)	ZA954826B (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE4442486A1 (de) *	1994-11-29	1996-05-30	Sigma Tau Ind Farmaceuti	Neue 17-(3-Imino-2-alkylpropylen)-5ß,14ß-androstan-Derivate, die auf das kardiovaskuläre System wirken, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Zusammensetzungen
IT1282289B1 (it) *	1995-06-23	1998-03-16	Sigma Tau Ind Farmaceuti	17-idrossiimminoalchil e 17-idrossiimminometilalchenil ciclopentaperidrofenantreni attivi sul sistema cardiovascolare,
US20030083231A1 (en) *	1998-11-24	2003-05-01	Ahlem Clarence N.	Blood cell deficiency treatment method
CN105218614B (zh) *	2015-10-29	2017-07-28	广西师范学院	4‑(4′‑溴)苯基‑2‑雌酮‑17′‑腙噻唑及其制备方法和用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DD235649C2 (de)	1985-03-22	1987-10-08	Akad Wissenschaften Ddr	Verfahren zur herstellung von 17beta-amino-5beta, 14beta-androstan-14-olen
US5144017A (en)	1988-07-13	1992-09-01	University Of Manitoba	Compounds that bind to digitalis receptor
DE4222404C1 (de) *	1992-07-08	1993-12-02	Sigma Tau Ind Farmaceuti	Verwendung von Iminoderivaten von Etianaldehyd zur Behandlung von Hypertonie
DE4227605C2 (de) *	1992-08-20	1995-02-16	Sigma Tau Ind Farmaceuti	17-Hydroxyiminomethyl-14beta-hydroxy-5ß-androstan-Derivate, Verfahren zu deren Herstellung und pharmazeutische Zusammensetzungen, die dieselben enthalten
DE4227626C2 (de)	1992-08-20	1994-11-17	Sigma Tau Ind Farmaceuti	17-Hydrazonomethyl-14ß-hydroxy-5ß-androstanderivate, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Zusammensetzungen
DE4344236A1 (de)	1993-12-23	1995-06-29	Sigma Tau Ind Farmaceuti	Neue 17-Iminomethylalkenyl-5beta,14beta-androstan- und 17-Iminoalkyl-5beta,14beta-androstan-Derivate , die auf das kardiovaskuläre System wirken, Verfahren zu ihrer Herstellung und pharmazeutische Zusammensetzungen, die sie enthalten

1994
- 1994-06-13 DE DE4420501A patent/DE4420501A1/de not_active Ceased
1995
- 1995-05-18 US US08/444,366 patent/US5599806A/en not_active Expired - Lifetime
- 1995-05-27 TW TW084105386A patent/TW293823B/zh active
- 1995-05-30 DK DK95108257.7T patent/DK0688786T3/da active
- 1995-05-30 ES ES95108257T patent/ES2105815T3/es not_active Expired - Lifetime
- 1995-05-30 EP EP95108257A patent/EP0688786B1/en not_active Expired - Lifetime
- 1995-05-30 AT AT95108257T patent/ATE156490T1/de not_active IP Right Cessation
- 1995-05-30 DE DE69500517T patent/DE69500517T2/de not_active Expired - Fee Related
- 1995-05-30 KR KR1019950013868A patent/KR100305739B1/ko not_active Expired - Fee Related
- 1995-06-12 CA CA002151561A patent/CA2151561C/en not_active Expired - Fee Related
- 1995-06-12 ZA ZA954826A patent/ZA954826B/xx unknown
- 1995-06-13 JP JP14620395A patent/JP3805406B2/ja not_active Expired - Fee Related
1997
- 1997-10-15 GR GR970402710T patent/GR3025064T3/el unknown

Also Published As

Publication number	Publication date
CA2151561C (en)	2006-01-24
DE69500517D1 (de)	1997-09-11
GR3025064T3 (en)	1998-01-30
EP0688786A1 (en)	1995-12-27
ES2105815T3 (es)	1997-10-16
DE4420501A1 (de)	1995-12-14
US5599806A (en)	1997-02-04
ZA954826B (en)	1996-01-30
DE69500517T2 (de)	1998-01-08
CA2151561A1 (en)	1995-12-14
KR960000916A (ko)	1996-01-25
TW293823B (da)	1996-12-21
JP3805406B2 (ja)	2006-08-02
EP0688786B1 (en)	1997-08-06
ATE156490T1 (de)	1997-08-15
KR100305739B1 (ko)	2001-11-30
JPH07330792A (ja)	1995-12-19

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