DK0526531T3 - Liposomer med positiv overskudsladning - Google Patents
Liposomer med positiv overskudsladningInfo
- Publication number
- DK0526531T3 DK0526531T3 DK91908541.5T DK91908541T DK0526531T3 DK 0526531 T3 DK0526531 T3 DK 0526531T3 DK 91908541 T DK91908541 T DK 91908541T DK 0526531 T3 DK0526531 T3 DK 0526531T3
- Authority
- DK
- Denmark
- Prior art keywords
- liposomes
- formula
- pnn
- gly
- excess charge
- Prior art date
Links
- 239000002502 liposome Substances 0.000 title abstract 4
- 239000013543 active substance Substances 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 208000019423 liver disease Diseases 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 125000002811 oleoyl group Chemical group O=C([*])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])/C([H])=C([H])\C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 1
- 125000001117 oleyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])/C([H])=C([H])\C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 1
- 210000000056 organ Anatomy 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
- A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Dispersion Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Manufacturing Of Micro-Capsules (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4013632A DE4013632A1 (de) | 1990-04-27 | 1990-04-27 | Liposomen mit positiver ueberschussladung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0526531T3 true DK0526531T3 (da) | 1994-08-22 |
Family
ID=6405307
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK91908541.5T DK0526531T3 (da) | 1990-04-27 | 1991-04-25 | Liposomer med positiv overskudsladning |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP0526531B1 (pt) |
| JP (1) | JPH05506661A (pt) |
| AT (1) | ATE107503T1 (pt) |
| AU (1) | AU643282B2 (pt) |
| CA (1) | CA2081119A1 (pt) |
| DE (2) | DE4013632A1 (pt) |
| DK (1) | DK0526531T3 (pt) |
| ES (1) | ES2056648T3 (pt) |
| IE (1) | IE62548B1 (pt) |
| PT (1) | PT97500B (pt) |
| WO (1) | WO1991016880A1 (pt) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH087409B2 (ja) * | 1988-10-03 | 1996-01-29 | 富士写真フイルム株式会社 | ハロゲン化銀カラー写真感光材料の処理方法 |
| US5264618A (en) * | 1990-04-19 | 1993-11-23 | Vical, Inc. | Cationic lipids for intracellular delivery of biologically active molecules |
| DE4208527A1 (de) * | 1992-03-17 | 1993-09-23 | Max Planck Gesellschaft | Liposomen mit negativer ueberschussladung |
| US5552155A (en) * | 1992-12-04 | 1996-09-03 | The Liposome Company, Inc. | Fusogenic lipsomes and methods for making and using same |
| EP0702516A4 (en) | 1993-06-01 | 1998-04-22 | Life Technologies Inc | GENETIC IMMUNIZATION WITH CATIONIC LIPIDS |
| EP0638639B1 (en) * | 1993-08-10 | 2000-04-12 | Akzo Nobel N.V. | Biodegradable fabric softening composition |
| NZ268146A (en) * | 1994-04-12 | 1997-10-24 | Liposome Co Inc | Liposome compositions and medicinal uses |
| US5429755A (en) * | 1994-06-16 | 1995-07-04 | Lever Brothers Company | Fabric conditioning molecules derived from glycerol and betaine |
| ES2123307T3 (es) * | 1995-02-24 | 1999-01-01 | Kao Corp | Sal de amonio cuaternario, metodo para la fabricacion de la misma y su utilizacion como composicion suavizante. |
| EP0863749A2 (en) | 1995-11-30 | 1998-09-16 | Vical Incorporated | Complex cationic lipids |
| DE19835611A1 (de) * | 1998-08-06 | 2000-02-10 | Max Planck Gesellschaft | Neuartige Phospholipide mit synthetischen, ungesättigten Alkyl- und Acylketten |
| EP1261620A2 (en) * | 2000-02-07 | 2002-12-04 | Roche Diagnostics Corporation | Cationic amphiphiles for use in nucleic acid transfection |
| ITMI20032185A1 (it) * | 2003-11-12 | 2005-05-13 | Chemi Spa | Processo per la sintesi di lipidi cationici. |
| DE102004057303A1 (de) * | 2004-11-26 | 2006-06-01 | Merck Patent Gmbh | Stabile Kristallmodifikationen von DOTAP Chlorid |
| CA2927045A1 (en) * | 2006-10-03 | 2008-04-10 | Muthiah Manoharan | Lipid containing formulations |
| NZ605079A (en) * | 2010-06-03 | 2015-08-28 | Alnylam Pharmaceuticals Inc | Biodegradable lipids for the delivery of active agents |
| ES2562274T3 (es) * | 2010-10-06 | 2016-03-03 | Fundació Institut De Recerca Biomèdica (Irb Barcelona) | Procedimiento para el diagnóstico, pronóstico y tratamiento de metástasis de cáncer de mama |
| SG194957A1 (en) | 2011-05-20 | 2013-12-30 | Merck Patent Gmbh | Stable crystal modifications of dotap chloride |
| JP2013043885A (ja) * | 2011-08-26 | 2013-03-04 | Kansai Bunri Sogo Gakuen | デヒドロアミノ酸含有グリセロール誘導体 |
| CA2856742A1 (en) | 2011-12-07 | 2013-06-13 | Alnylam Pharmaceuticals, Inc. | Biodegradable lipids for the delivery of active agents |
| EP2650682A1 (en) | 2012-04-09 | 2013-10-16 | Fundació Privada Institut de Recerca Biomèdica | Method for the prognosis and treatment of cancer metastasis |
| CN117230193A (zh) | 2016-05-25 | 2023-12-15 | 生物运动有限公司 | 基于c-maf状态的乳腺癌治疗性治疗 |
| EP3713581A1 (en) | 2017-11-22 | 2020-09-30 | Inbiomotion S.L. | Therapeutic treatment of breast cancer based on c-maf |
| KR102054401B1 (ko) * | 2018-03-26 | 2019-12-10 | 주식회사 엔지켐생명과학 | 1,2-디아실글리세롤 화합물, 그 제조방법 및 이를 유효성분으로 함유하는 면역조절제 |
| EP4368609A1 (en) * | 2022-11-08 | 2024-05-15 | Mello Biotech Taiwan Co., Ltd. | Cationic lipids and uses thereof |
| KR20240174509A (ko) | 2023-06-07 | 2024-12-17 | 포항공과대학교 산학협력단 | 핵산 치료제에 사용되는 기능성 지질 라이브러리를 합성하기 위한 단일 연속 유동 합성 방법 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2752553C2 (de) * | 1977-11-24 | 1985-07-25 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen | Neue phospholipidartige Verbindungen, ihre Verwendung zur Herstellung von Pflanzenhybriden und Verfahren zu ihrer Herstellung |
| AU5632880A (en) * | 1979-04-30 | 1980-11-06 | Brown, G. | Convertible sleeping and seating apparatus |
| DE3374837D1 (en) * | 1982-02-17 | 1988-01-21 | Ciba Geigy Ag | Lipids in the aqueous phase |
| ZA8681B (en) * | 1985-01-07 | 1987-08-26 | Syntex Inc | 1,2-dialkoxy-omega-trialkylammonium cationic surfactants |
| US5223263A (en) * | 1988-07-07 | 1993-06-29 | Vical, Inc. | Liponucleotide-containing liposomes |
| JPS632921A (ja) * | 1986-06-20 | 1988-01-07 | Yamanouchi Pharmaceut Co Ltd | リポソ−ム製剤 |
-
1990
- 1990-04-27 DE DE4013632A patent/DE4013632A1/de not_active Withdrawn
-
1991
- 1991-04-25 JP JP91508158A patent/JPH05506661A/ja active Pending
- 1991-04-25 CA CA002081119A patent/CA2081119A1/en not_active Abandoned
- 1991-04-25 ES ES91908541T patent/ES2056648T3/es not_active Expired - Lifetime
- 1991-04-25 DE DE59102030T patent/DE59102030D1/de not_active Expired - Fee Related
- 1991-04-25 AU AU77702/91A patent/AU643282B2/en not_active Ceased
- 1991-04-25 AT AT91908541T patent/ATE107503T1/de not_active IP Right Cessation
- 1991-04-25 EP EP91908541A patent/EP0526531B1/de not_active Expired - Lifetime
- 1991-04-25 WO PCT/EP1991/000796 patent/WO1991016880A1/de not_active Ceased
- 1991-04-25 DK DK91908541.5T patent/DK0526531T3/da active
- 1991-04-26 PT PT97500A patent/PT97500B/pt not_active IP Right Cessation
- 1991-04-26 IE IE142791A patent/IE62548B1/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ATE107503T1 (de) | 1994-07-15 |
| AU7770291A (en) | 1991-11-27 |
| WO1991016880A1 (de) | 1991-11-14 |
| DE59102030D1 (de) | 1994-07-28 |
| IE62548B1 (en) | 1995-02-08 |
| EP0526531B1 (de) | 1994-06-22 |
| PT97500B (pt) | 1998-08-31 |
| IE911427A1 (en) | 1991-11-06 |
| EP0526531A1 (de) | 1993-02-10 |
| DE4013632A1 (de) | 1991-10-31 |
| PT97500A (pt) | 1992-01-31 |
| AU643282B2 (en) | 1993-11-11 |
| CA2081119A1 (en) | 1991-10-28 |
| JPH05506661A (ja) | 1993-09-30 |
| ES2056648T3 (es) | 1994-10-01 |
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