DK0593766T3 - Pyridoncarboxylsyrederivat - Google Patents
PyridoncarboxylsyrederivatInfo
- Publication number
- DK0593766T3 DK0593766T3 DK92910698T DK92910698T DK0593766T3 DK 0593766 T3 DK0593766 T3 DK 0593766T3 DK 92910698 T DK92910698 T DK 92910698T DK 92910698 T DK92910698 T DK 92910698T DK 0593766 T3 DK0593766 T3 DK 0593766T3
- Authority
- DK
- Denmark
- Prior art keywords
- represent
- various
- derivatives
- quinolone
- formula
- Prior art date
Links
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- 230000000844 anti-bacterial effect Effects 0.000 abstract 2
- 150000007660 quinolones Chemical class 0.000 abstract 2
- YSLIPUSJNFIFAB-UHFFFAOYSA-N 2-oxopyridine-1-carboxylic acid Chemical group OC(=O)N1C=CC=CC1=O YSLIPUSJNFIFAB-UHFFFAOYSA-N 0.000 abstract 1
- 229940088710 antibiotic agent Drugs 0.000 abstract 1
- 125000001028 difluoromethyl group Chemical group [H]C(F)(F)* 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Communicable Diseases (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyridine Compounds (AREA)
- Cephalosporin Compounds (AREA)
- Quinoline Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Stringed Musical Instruments (AREA)
- Table Devices Or Equipment (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP22542591 | 1991-05-28 | ||
| PCT/JP1992/000687 WO1992021659A1 (fr) | 1991-05-28 | 1992-05-27 | Derive d'acide pyridonecarboxylique |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0593766T3 true DK0593766T3 (da) | 2000-10-09 |
Family
ID=16829173
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK92910698T DK0593766T3 (da) | 1991-05-28 | 1992-05-27 | Pyridoncarboxylsyrederivat |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US5696132A (fr) |
| EP (1) | EP0593766B1 (fr) |
| JP (1) | JP3215500B2 (fr) |
| KR (1) | KR100232937B1 (fr) |
| AT (1) | ATE196135T1 (fr) |
| AU (1) | AU661999B2 (fr) |
| CA (1) | CA2110260C (fr) |
| DE (1) | DE69231422T2 (fr) |
| DK (1) | DK0593766T3 (fr) |
| ES (1) | ES2151488T3 (fr) |
| FI (1) | FI109201B (fr) |
| GR (1) | GR3034966T3 (fr) |
| NO (1) | NO180780C (fr) |
| RU (1) | RU2100351C1 (fr) |
| TW (1) | TW212179B (fr) |
| WO (1) | WO1992021659A1 (fr) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3165742B2 (ja) * | 1991-07-16 | 2001-05-14 | 中外製薬株式会社 | キノロンカルボン酸誘導体の製造方法 |
| NO304832B1 (no) * | 1992-05-27 | 1999-02-22 | Ube Industries | Aminokinolonderivater samt middel mot HIV |
| NO301165B1 (no) * | 1992-12-25 | 1997-09-22 | Daiichi Seiyaku Co | Bicykliske aminderivater og antibakterielle midler inneholdende disse |
| DE4339134A1 (de) * | 1993-11-16 | 1995-05-18 | Bayer Ag | 1-(2-Fluorcyclopropyl)-chinolon- und -naphthyridoncarbonsäure-Derivate |
| DE4408212A1 (de) * | 1994-03-11 | 1995-09-14 | Bayer Ag | 5-Vinyl- und 5-Ethinyl-chinolon- und -naphthyridon-carbonsäuren |
| DK0807630T3 (da) * | 1995-02-02 | 2003-09-01 | Daiichi Seiyaku Co | Heterocykliske forbindelser |
| TW466237B (en) * | 1995-02-07 | 2001-12-01 | Daiichi Seiyaku Co | Heterocyclic spiro-derivative |
| EP0911328B1 (fr) * | 1995-11-22 | 2006-02-08 | Daiichi Pharmaceutical Co., Ltd. | Derives a base d'aminocycloalkylpyrrolidine substituee |
| US6121285A (en) * | 1995-11-22 | 2000-09-19 | Daiichi Pharmaceutical Co., Ltd. | Substituted aminocycloalkylpyrrolidine derivatives and cis-substituted aminocycloalkylpyrrolidine derivatives |
| WO1998024781A1 (fr) * | 1996-12-04 | 1998-06-11 | Daiichi Pharmaceutical Co., Ltd. | Derives d'aminomethylpyrrolidine substitue |
| JPH1149698A (ja) | 1997-07-31 | 1999-02-23 | Santen Pharmaceut Co Ltd | 安定性を向上させたラクトフェリンの水性製剤 |
| US7977327B2 (en) | 2004-05-13 | 2011-07-12 | Daiichi Sankyo Company, Limited | Substituted pyrrolidine derivative |
| ES2349278T3 (es) * | 2004-11-17 | 2010-12-29 | Wakunaga Pharmaceutical Co., Ltd. | Nuevos derivados de ácido piridoncarboxílico y una sal del mismo. |
| US7563805B2 (en) * | 2005-05-19 | 2009-07-21 | Daiichi Pharmaceutical Co., Ltd. | Tri-, tetra-substituted-3-aminopyrrolidine derivative |
| US7977346B2 (en) | 2006-01-17 | 2011-07-12 | Guoqing Paul Chen | Spiro compounds and methods of use |
| CN105330590B (zh) * | 2015-10-15 | 2018-09-25 | 广州市朗启医药科技有限责任公司 | 西他沙星五元环侧链中间体的制备方法 |
| CN109942488A (zh) * | 2019-04-04 | 2019-06-28 | 山东省联合农药工业有限公司 | 一种喹啉羧酸酯类化合物及其制备方法与用途 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6028978A (ja) * | 1983-07-27 | 1985-02-14 | Dainippon Pharmaceut Co Ltd | １，８−ナフチリジン誘導体 |
| DE3576335D1 (de) * | 1984-12-14 | 1990-04-12 | Daiichi Seiyaku Co | Chinolincarbonsaeure-derivate. |
| DE3509546A1 (de) * | 1985-03-16 | 1986-09-25 | Bayer Ag, 5090 Leverkusen | 7-amino-1-(subst.cyclopropyl)-1,4-dihydro-4-oxo-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel |
| DE3705621C2 (de) * | 1986-02-25 | 1997-01-09 | Otsuka Pharma Co Ltd | Heterocyclisch substituierte Chinoloncarbonsäurederivate |
| DE3702393A1 (de) * | 1987-01-28 | 1988-08-11 | Bayer Ag | 8-cyano-1-cyclopropyl-1,4-dihydro-4-oxo- 3-chinolincarbonsaeuren, verfahren zu ihrer herstellung und diese enthaltende antibakterielle mittel |
| US5563138A (en) * | 1987-04-16 | 1996-10-08 | Otsuka Pharmaceutical Company, Limited | Benzoheterocyclic compounds |
| US4851418A (en) * | 1987-08-21 | 1989-07-25 | Warner-Lambert Company | Naphthyridine antibacterial agents containing an α-amino acid in the side chain of the 7-substituent |
| US4920120A (en) * | 1988-01-25 | 1990-04-24 | Warner-Lambert Company | Antibacterial agents |
| MY105136A (en) * | 1988-04-27 | 1994-08-30 | Daiichi Seiyaku Co | Optically active pyridonecarboxylic acid derivatives. |
| DE3906365A1 (de) * | 1988-07-15 | 1990-01-18 | Bayer Ag | 7-(1-pyrrolidinyl)-3-chinolon- und -naphthyridoncarbonsaeure-derivate, verfahren sowie substituierte (oxa)diazabicyclooctane und -nonane als zwischenprodukte zu ihrer herstellung, und sie enthaltende antibakterielle mittel und futterzusatzstoffe |
| US5057520A (en) * | 1989-03-24 | 1991-10-15 | Abbott Laboratories | 7-(peptidylpyrolidinyl)naphthyridine antibacterial compounds |
| EP0390215B1 (fr) * | 1989-03-30 | 1995-06-07 | Wakunaga Seiyaku Kabushiki Kaisha | Dérivés de quinolone et leurs sels, procédés pour leur préparation et agents antibactériens les contenant |
| DE3910663A1 (de) * | 1989-04-03 | 1990-10-04 | Bayer Ag | 5-alkylchinoloncarbonsaeuren |
| US5140033A (en) * | 1989-04-03 | 1992-08-18 | Bayer Aktiengesellschaft | Antibacterial 5-alkylquinolonecarboxylic acids |
| US5252734A (en) * | 1989-04-03 | 1993-10-12 | Bayer Aktiengesellschaft | Antibacterial 5-alkylquinolonecarboxylic acids |
| DE3918544A1 (de) * | 1989-06-07 | 1990-12-13 | Bayer Ag | Verfahren zur herstellung von 7-(3-amino- sowie 3-amino-methyl-1-pyrrolidinyl)-3-chinolon- carbonsaeuren sowie -naphthyridoncarbonsaeuren |
| MY109714A (en) * | 1990-10-18 | 1997-04-30 | Daiichi Seiyaku Co | Process for preparing 8-chloroquinolone derivatives |
| US5072001A (en) * | 1990-11-30 | 1991-12-10 | Warner-Lambert Company | Certain optically active substituted 3-pyrraidine acetic acid derivatives useful as intermediates |
| US5137892A (en) * | 1990-12-12 | 1992-08-11 | Abbott Laboratories | Quinoline, naphthyridine and pyridobenzoxazine derivatives |
-
1992
- 1992-05-27 AT AT92910698T patent/ATE196135T1/de not_active IP Right Cessation
- 1992-05-27 CA CA002110260A patent/CA2110260C/fr not_active Expired - Fee Related
- 1992-05-27 RU RU93058417/04A patent/RU2100351C1/ru not_active IP Right Cessation
- 1992-05-27 WO PCT/JP1992/000687 patent/WO1992021659A1/fr not_active Ceased
- 1992-05-27 ES ES92910698T patent/ES2151488T3/es not_active Expired - Lifetime
- 1992-05-27 US US08/142,444 patent/US5696132A/en not_active Expired - Fee Related
- 1992-05-27 EP EP92910698A patent/EP0593766B1/fr not_active Expired - Lifetime
- 1992-05-27 AU AU18872/92A patent/AU661999B2/en not_active Ceased
- 1992-05-27 DE DE69231422T patent/DE69231422T2/de not_active Expired - Fee Related
- 1992-05-27 KR KR1019930703606A patent/KR100232937B1/ko not_active Expired - Fee Related
- 1992-05-27 DK DK92910698T patent/DK0593766T3/da active
- 1992-05-28 JP JP13650492A patent/JP3215500B2/ja not_active Expired - Fee Related
- 1992-05-29 TW TW081104208A patent/TW212179B/zh active
-
1993
- 1993-11-25 FI FI935243A patent/FI109201B/fi not_active IP Right Cessation
- 1993-11-26 NO NO934279A patent/NO180780C/no not_active IP Right Cessation
-
2000
- 2000-11-30 GR GR20000402669T patent/GR3034966T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ATE196135T1 (de) | 2000-09-15 |
| FI935243L (fi) | 1994-01-11 |
| JP3215500B2 (ja) | 2001-10-09 |
| DE69231422T2 (de) | 2001-03-29 |
| DE69231422D1 (de) | 2000-10-12 |
| AU1887292A (en) | 1993-01-08 |
| FI109201B (fi) | 2002-06-14 |
| WO1992021659A1 (fr) | 1992-12-10 |
| EP0593766A1 (fr) | 1994-04-27 |
| KR100232937B1 (ko) | 1999-12-01 |
| EP0593766A4 (fr) | 1994-12-07 |
| CA2110260A1 (fr) | 1992-12-10 |
| CA2110260C (fr) | 2001-12-04 |
| ES2151488T3 (es) | 2001-01-01 |
| TW212179B (fr) | 1993-09-01 |
| US5696132A (en) | 1997-12-09 |
| FI935243A0 (fi) | 1993-11-25 |
| NO934279L (no) | 1994-01-28 |
| GR3034966T3 (en) | 2001-02-28 |
| JPH05163244A (ja) | 1993-06-29 |
| AU661999B2 (en) | 1995-08-17 |
| EP0593766B1 (fr) | 2000-09-06 |
| NO180780B (no) | 1997-03-10 |
| NO934279D0 (no) | 1993-11-26 |
| RU2100351C1 (ru) | 1997-12-27 |
| NO180780C (no) | 1997-06-18 |
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