DK0450566T3 - Substituerede azoler, fremgangsmåde til deres fremstilling, midler indeholdende disse og deres anvendelse - Google Patents

Substituerede azoler, fremgangsmåde til deres fremstilling, midler indeholdende disse og deres anvendelse

Info

Publication number: DK0450566T3
Authority: DK; Denmark
Prior art keywords: preparation; processes; agents containing; substituted azoles; azoles
Prior art date: 1990-04-04

Application number

DK91105178.7T

Other languages

English (en)

Inventor

Adalbert Dr Wagner

Rainer Dr Henning

Hermann Dr Gerhards

Bernward Dr Schoelkens

Vevert Jean-Paul

Caille Jean-Claude

Original Assignee

Hoechst Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-04-04

Filing date

1991-04-02

Publication date

1995-10-30

1991-04-02 Application filed by Hoechst Ag filed Critical Hoechst Ag

1995-10-30 Application granted granted Critical

1995-10-30 Publication of DK0450566T3 publication Critical patent/DK0450566T3/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Heart & Thoracic Surgery (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Cardiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Coloring (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Detergent Compositions (AREA)
Pyrrole Compounds (AREA)
Cephalosporin Compounds (AREA)

DK91105178.7T 1990-04-04 1991-04-02 Substituerede azoler, fremgangsmåde til deres fremstilling, midler indeholdende disse og deres anvendelse DK0450566T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE4010797A DE4010797A1 (de)	1990-04-04	1990-04-04	Substituierte azole, verfahren zu deren herstellung, diese enthaltende mittel und deren verwendung

Publications (1)

Publication Number	Publication Date
DK0450566T3 true DK0450566T3 (da)	1995-10-30

Family

ID=6403704

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK91105178.7T DK0450566T3 (da)	1990-04-04	1991-04-02	Substituerede azoler, fremgangsmåde til deres fremstilling, midler indeholdende disse og deres anvendelse

Country Status (25)

Country	Link
US (2)	US5350751A (da)
EP (1)	EP0450566B1 (da)
JP (1)	JP3212036B2 (da)
KR (1)	KR910018376A (da)
CN (2)	CN1031940C (da)
AT (1)	ATE124696T1 (da)
AU (2)	AU644857B2 (da)
CA (1)	CA2039622A1 (da)
CZ (1)	CZ280248B6 (da)
DE (2)	DE4010797A1 (da)
DK (1)	DK0450566T3 (da)
ES (1)	ES2076395T3 (da)
FI (1)	FI911584A7 (da)
HU (2)	HU213096B (da)
IE (1)	IE67790B1 (da)
IL (1)	IL97760A (da)
MA (1)	MA22112A1 (da)
MX (1)	MX25204A (da)
MY (1)	MY109937A (da)
NO (1)	NO177266C (da)
NZ (2)	NZ260561A (da)
PT (1)	PT97254B (da)
RU (2)	RU2060255C1 (da)
SK (1)	SK278797B6 (da)
ZA (1)	ZA912458B (da)

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DE4010797A1 (de) *	1990-04-04	1991-10-10	Hoechst Ag	Substituierte azole, verfahren zu deren herstellung, diese enthaltende mittel und deren verwendung
DE4023215A1 (de) *	1990-07-21	1992-01-23	Hoechst Ag	Substituierte azole, verfahren zu deren herstellung, sie enthaltende mittel und deren verwendung
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DE4036706A1 (de) *	1990-11-17	1992-05-21	Hoechst Ag	Verfahren zur behandlung der cardialen sowie der vasculaeren hypertrophie und hyperplasie
CA2058198A1 (en) *	1991-01-04	1992-07-05	Adalbert Wagner	Azole derivatives, process for their preparation, and their use
TW197428B (da)	1991-01-04	1993-01-01	Hoechst Ag
CA2061159A1 (en) *	1991-02-26	1992-08-27	Michael A. Poss	Imidazole and benzimidazole derivatives
GB9108811D0 (en) *	1991-04-24	1991-06-12	Erba Carlo Spa	N-imidazolyl derivatives of substituted indole
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EP0614889A1 (de) *	1993-03-12	1994-09-14	Lonza Ag	Verfahren zur Herstellung von gegebenenfalls 2-substituierten 5-Chlorimidazol-4-carbaldehyden
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CA2467095A1 (en) *	2001-11-23	2003-05-30	Solvay Pharmaceuticals Gmbh	Hypertonia treatment during the acute phase of a cerebrovascular accident
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US8969514B2 (en)	2007-06-04	2015-03-03	Synergy Pharmaceuticals, Inc.	Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
US20100120694A1 (en)	2008-06-04	2010-05-13	Synergy Pharmaceuticals, Inc.	Agonists of Guanylate Cyclase Useful for the Treatment of Gastrointestinal Disorders, Inflammation, Cancer and Other Disorders
JP5546451B2 (ja)	2007-06-04	2014-07-09	シナジーファーマシューティカルズインコーポレイテッド	胃腸の障害、炎症、癌および他の障害の処置に有用なグアニル酸シクラーゼのアゴニスト
EP3241839B1 (en)	2008-07-16	2019-09-04	Bausch Health Ireland Limited	Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
US20130005721A1 (en) *	2009-09-23	2013-01-03	Panmira Pharmaceuticals, Llc	Indolizine inhibitors of 5-lipoxygenase
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EP2496578A4 (en)	2009-11-05	2013-08-21	Univ Notre Dame Du Lac	IMIDAZO [1,2-A] PYRIDINE COMPOUNDS, THEIR SYNTHESIS AND METHODS OF USE THEREOF
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US4859691A (en) *	1987-07-08	1989-08-22	Ciba-Geigy Corporation	Certain 1,2-benzisoxazole derivatives
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DE4010797A1 (de) *	1990-04-04	1991-10-10	Hoechst Ag	Substituierte azole, verfahren zu deren herstellung, diese enthaltende mittel und deren verwendung
DE4023215A1 (de) *	1990-07-21	1992-01-23	Hoechst Ag	Substituierte azole, verfahren zu deren herstellung, sie enthaltende mittel und deren verwendung
TW215434B (da) *	1992-03-07	1993-11-01	Hoechst Ag

1990
- 1990-04-04 DE DE4010797A patent/DE4010797A1/de not_active Withdrawn
1991
- 1991-03-28 NZ NZ260561A patent/NZ260561A/xx unknown
- 1991-03-28 NZ NZ237644A patent/NZ237644A/en unknown
- 1991-04-02 DE DE59105897T patent/DE59105897D1/de not_active Expired - Lifetime
- 1991-04-02 US US07/679,233 patent/US5350751A/en not_active Expired - Lifetime
- 1991-04-02 AT AT91105178T patent/ATE124696T1/de not_active IP Right Cessation
- 1991-04-02 DK DK91105178.7T patent/DK0450566T3/da active
- 1991-04-02 SK SK906-91A patent/SK278797B6/sk unknown
- 1991-04-02 CZ CS91906A patent/CZ280248B6/cs not_active IP Right Cessation
- 1991-04-02 EP EP91105178A patent/EP0450566B1/de not_active Expired - Lifetime
- 1991-04-02 FI FI911584A patent/FI911584A7/fi unknown
- 1991-04-02 ES ES91105178T patent/ES2076395T3/es not_active Expired - Lifetime
- 1991-04-02 MY MYPI91000552A patent/MY109937A/en unknown
- 1991-04-03 ZA ZA912458A patent/ZA912458B/xx unknown
- 1991-04-03 IE IE109891A patent/IE67790B1/en not_active IP Right Cessation
- 1991-04-03 JP JP09611991A patent/JP3212036B2/ja not_active Expired - Lifetime
- 1991-04-03 NO NO911302A patent/NO177266C/no unknown
- 1991-04-03 RU SU914894882A patent/RU2060255C1/ru active
- 1991-04-03 CA CA002039622A patent/CA2039622A1/en not_active Abandoned
- 1991-04-03 AU AU74013/91A patent/AU644857B2/en not_active Ceased
- 1991-04-03 IL IL97760A patent/IL97760A/xx not_active IP Right Cessation
- 1991-04-03 CN CN91102043A patent/CN1031940C/zh not_active Expired - Fee Related
- 1991-04-03 MX MX2520491A patent/MX25204A/es unknown
- 1991-04-04 MA MA22381A patent/MA22112A1/fr unknown
- 1991-04-04 PT PT97254A patent/PT97254B/pt not_active IP Right Cessation
- 1991-04-04 HU HU911091A patent/HU213096B/hu not_active IP Right Cessation
- 1991-04-04 KR KR1019910005416A patent/KR910018376A/ko not_active Abandoned
1993
- 1993-12-21 AU AU52560/93A patent/AU658781B2/en not_active Ceased
1994
- 1994-05-27 US US08/250,491 patent/US5440046A/en not_active Expired - Lifetime
- 1994-10-22 CN CN94117640A patent/CN1036263C/zh not_active Expired - Fee Related
1995
- 1995-05-30 RU RU9595108590A patent/RU2092482C1/ru active
- 1995-06-28 HU HU95P/P00507P patent/HU211464A9/hu unknown

Also Published As

Publication number	Publication date
RU2092482C1 (ru)	1997-10-10
KR910018376A (ko)	1991-11-30
NO177266C (no)	1995-08-16
EP0450566A1 (de)	1991-10-09
IE67790B1 (en)	1996-04-17
FI911584A0 (fi)	1991-04-02
NZ260561A (en)	1995-01-27
CN1105993A (zh)	1995-08-02
AU644857B2 (en)	1993-12-23
AU658781B2 (en)	1995-04-27
MY109937A (en)	1997-10-31
US5350751A (en)	1994-09-27
JP3212036B2 (ja)	2001-09-25
CN1055361A (zh)	1991-10-16
CN1036263C (zh)	1997-10-29
ES2076395T3 (es)	1995-11-01
MX25204A (es)	1993-08-01
AU5256093A (en)	1994-02-24
NO911302D0 (no)	1991-04-03
FI911584L (fi)	1991-10-05
NO177266B (no)	1995-05-08
ATE124696T1 (de)	1995-07-15
RU2060255C1 (ru)	1996-05-20
PT97254A (pt)	1992-01-31
EP0450566B1 (de)	1995-07-05
NZ237644A (en)	1994-12-22
NO911302L (no)	1991-10-07
CA2039622A1 (en)	1991-10-05
HU211464A9 (en)	1995-11-28
HU911091D0 (en)	1991-10-28
IE911098A1 (en)	1991-10-09
HU213096B (en)	1997-02-28
IL97760A (en)	1997-06-10
DE4010797A1 (de)	1991-10-10
IL97760A0 (en)	1992-06-21
CN1031940C (zh)	1996-06-05
US5440046A (en)	1995-08-08
FI911584A7 (fi)	1991-10-05
AU7401391A (en)	1991-10-10
CS9100906A2 (en)	1991-11-12
RU95108590A (ru)	1997-03-20
SK278797B6 (sk)	1998-03-04
CZ280248B6 (cs)	1995-12-13
DE59105897D1 (de)	1995-08-10
PT97254B (pt)	1998-07-31
ZA912458B (en)	1991-12-24
MA22112A1 (fr)	1991-12-31
HUT60734A (en)	1992-10-28
JPH04234876A (ja)	1992-08-24

Publication	Publication Date	Title
DK0450566T3 (da)	1995-10-30	Substituerede azoler, fremgangsmåde til deres fremstilling, midler indeholdende disse og deres anvendelse
DK599785A (da)	1986-06-22	Blokpolyestere og detergentkompositioner indeholdende disse
IL73258A0 (en)	1985-01-31	7-aminoazolo(1,5-a)pyrimidines,their preparation and their use as fungicides
DE69133397D1 (de)	2004-07-22	Benzoylderivate
PL295030A1 (en)	1993-05-31	Method of obtaining substituted derivatives of 2-cyclohexan-1-yl amine
DK0532515T3 (da)	1997-04-21	Fremstilling af substituerede piperidiner
GR79462B (da)	1984-10-30
ATE76405T1 (de)	1992-06-15	2-trifluormethyl-benzimidazole.
NO930205L (no)	1993-07-23	Benzimidazoler, legemidler inneholdende disse, og fremgangsmaate for deres fremstilling
NO892189L (no)	1989-12-04	Trijodbenzenforbindelser og kontrastmidler for radiografiinneholdende disse.
DK440987A (da)	1988-02-26	Thyroninderivater, deres fremstilling og anvendelse
DK394285A (da)	1986-03-01	Benzodisultamer, deres fremstilling og anvendelse
ES2054631T3 (es)	1994-08-16	1-(2-halogeno-alcoxi-bencenosulfonil)-3-heteroaril-ureas, 3-substituidas.