DK0532515T3 - Fremstilling af substituerede piperidiner - Google Patents

Fremstilling af substituerede piperidiner

Info

Publication number: DK0532515T3
Authority: DK; Denmark
Prior art keywords: preparation; substituted piperidines; processes; novel; piperidines
Prior art date: 1990-05-31

Application number

DK91908255.2T

Other languages

English (en)

Inventor

Dennis M Godek

Terry J Rosen

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-05-31

Filing date

1991-04-12

Publication date

1997-04-21

1991-04-12 Application filed by Pfizer filed Critical Pfizer

1997-04-21 Application granted granted Critical

1997-04-21 Publication of DK0532515T3 publication Critical patent/DK0532515T3/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/73—Unsubstituted amino or imino radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Hydrogenated Pyridines (AREA)
Plural Heterocyclic Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pyridine Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

DK91908255.2T 1990-05-31 1991-04-12 Fremstilling af substituerede piperidiner DK0532515T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US53126590A	1990-05-31	1990-05-31

Publications (1)

Publication Number	Publication Date
DK0532515T3 true DK0532515T3 (da)	1997-04-21

Family

ID=24116944

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK91908255.2T DK0532515T3 (da)	1990-05-31	1991-04-12	Fremstilling af substituerede piperidiner

Country Status (26)

Country	Link
EP (1)	EP0532515B1 (da)
JP (2)	JPH0794439B2 (da)
KR (1)	KR0160142B1 (da)
CN (2)	CN1037768C (da)
AT (1)	ATE144498T1 (da)
AU (1)	AU648558B2 (da)
BR (1)	BR9106518A (da)
CA (1)	CA2080249C (da)
CZ (1)	CZ284663B6 (da)
DE (1)	DE69122866T2 (da)
DK (1)	DK0532515T3 (da)
ES (1)	ES2093099T3 (da)
FI (1)	FI101376B (da)
GR (1)	GR3022079T3 (da)
HU (1)	HU226529B1 (da)
IE (1)	IE911841A1 (da)
IL (3)	IL113011A (da)
MY (1)	MY107819A (da)
NO (1)	NO180083C (da)
NZ (2)	NZ238340A (da)
PL (2)	PL169187B1 (da)
PT (1)	PT97796B (da)
RU (1)	RU2077531C1 (da)
WO (1)	WO1991018878A1 (da)
YU (1)	YU48030B (da)
ZA (1)	ZA914133B (da)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
UA41251C2 (uk) *	1990-01-04	2001-09-17	Пфайзер, Інк.	Гідровані азотвмісні гетероциклічні сполуки, похідні піперидину, фармацевтична композиція та спосіб пригнічення активності речовини р в організмі
US5332817A (en) *	1990-01-04	1994-07-26	Pfizer Inc.	3-aminopiperidine derivatives and related nitrogen containing heterocycles
US5364943A (en) *	1991-11-27	1994-11-15	Pfizer Inc.	Preparation of substituted piperidines
CZ293955B6 (cs) *	1991-03-26	2004-08-18	Pfizeráinc	Postup přípravy substituovaných piperidinů
MY110227A (en) *	1991-08-12	1998-03-31	Ciba Geigy Ag	1-acylpiperindine compounds.
HUT70741A (en) *	1991-11-12	1995-10-30	Pfizer	Acyclic ethylenediamine derivatives as substance p receptor antagonists
JP2722279B2 (ja) *	1992-12-10	1998-03-04	ファイザー・インク．	アミノメチレンで置換した非芳香族複素環式化合物及びサブスタンスｐのアンタゴニストとしての使用
EP0700384B1 (en) *	1993-05-28	1997-07-16	Pfizer Inc.	Process for preparing and resolving 2-phenyl-3-aminopiperidine
TW397825B (en) *	1994-10-14	2000-07-11	Novartis Ag	Aroyl-piperidine derivatives
FR2728165A1 (fr)	1994-12-19	1996-06-21	Oreal	Utilisation d'un antagoniste de substance p pour le traitement des rougeurs cutanees d'origine neurogene
FR2728169A1 (fr)	1994-12-19	1996-06-21	Oreal	Utilisation d'un antagoniste de substance p pour le traitement des prurits et des dysesthesies oculaires ou palpebrales
FR2728166A1 (fr)	1994-12-19	1996-06-21	Oreal	Composition topique contenant un antagoniste de substance p
FR2741262B1 (fr)	1995-11-20	1999-03-05	Oreal	Utilisation d'un antagoniste de tnf-alpha pour le traitement des rougeurs cutanees d'origine neurogene
US6214846B1 (en)	1997-06-27	2001-04-10	Merck Sharp & Dohme Limited	Substituted 3-(benzylamino)piperidine derivatives and their use as therapeutic agents
EP1098881A1 (en) *	1998-07-21	2001-05-16	Syngenta Participations AG	3-substituted pyridine compounds and related synthesis
RU2238264C2 (ru) *	1999-02-24	2004-10-20	Ф.Хоффманн-Ля Рош Аг	Производные бензола или пиридина и фармацевтическая композиция на их основе
JP4068305B2 (ja) *	1999-02-24	2008-03-26	エフ．ホフマン−ラロシュアーゲー	３−フェニルピリジン誘導体、およびそのｎｋ−１受容体拮抗薬としての用途
RS49964B (sr) *	1999-05-17	2008-09-29	Pfizer Products Inc.,	Postupak za dobijanje 2-fenil-3-aminopiridina,njegovih supstituisanih fenil derivata, i njegovih soli
TWI259180B (en) *	2000-08-08	2006-08-01	Hoffmann La Roche	4-Phenyl-pyridine derivatives
JP2011016751A (ja) *	2009-07-08	2011-01-27	Sumitomo Chemical Co Ltd	光学活性３−アミノピペリジン−１−カルボキシレート化合物の製造方法およびその製造方法に用いられる中間体
CN111808017B (zh) *	2020-08-05	2023-11-28	国家纳米科学中心	一种含氮杂环化合物及其制备方法和应用
CN116162055B (zh) *	2023-03-10	2023-09-12	山东汇智药物研究有限公司	一种用n-氧化吡啶衍生物制备哌啶衍生物的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS52125170A (en) *	1976-04-12	1977-10-20	Yoshitomi Pharmaceut Ind Ltd	Pyridine derivatives
CA1160229A (en) *	1979-03-13	1984-01-10	Pieter T. Haken	Pyridyliminomethylbenzene derivatives
GB2056974B (en) *	1979-07-19	1984-02-29	Shell Int Research	Heterocyclic acylamino compounds having fungicidal herbicidal and plant-growth regulating properties
CA1231710A (en) *	1979-07-19	1988-01-19	Haken Pieter Ten	Heterocyclic compounds having fungicidal, herbicidal and plant-growth regulating properties
EP0100158A3 (en) *	1982-07-28	1985-03-27	The Upjohn Company	(3-pyridinyl)heteroalkarylalkanols, alkanoic acids and esters
US4552960A (en) *	1983-06-20	1985-11-12	Eli Lilly And Company	Fungicidal amines
FR2662696A2 (fr) *	1989-12-13	1991-12-06	Rhone Poulenc Sante	Antagonistes de la serotonine, leur preparation et medicaments les contenant.
UA41251C2 (uk) *	1990-01-04	2001-09-17	Пфайзер, Інк.	Гідровані азотвмісні гетероциклічні сполуки, похідні піперидину, фармацевтична композиція та спосіб пригнічення активності речовини р в організмі

1991
- 1991-04-12 EP EP91908255A patent/EP0532515B1/en not_active Expired - Lifetime
- 1991-04-12 ES ES91908255T patent/ES2093099T3/es not_active Expired - Lifetime
- 1991-04-12 PL PL91309053A patent/PL169187B1/pl unknown
- 1991-04-12 WO PCT/US1991/002541 patent/WO1991018878A1/en not_active Ceased
- 1991-04-12 HU HU9203761A patent/HU226529B1/hu not_active IP Right Cessation
- 1991-04-12 DE DE69122866T patent/DE69122866T2/de not_active Expired - Fee Related
- 1991-04-12 CA CA002080249A patent/CA2080249C/en not_active Expired - Fee Related
- 1991-04-12 JP JP3508366A patent/JPH0794439B2/ja not_active Expired - Fee Related
- 1991-04-12 KR KR1019920703014A patent/KR0160142B1/ko not_active Expired - Fee Related
- 1991-04-12 AT AT91908255T patent/ATE144498T1/de not_active IP Right Cessation
- 1991-04-12 RU RU9192016444A patent/RU2077531C1/ru not_active IP Right Cessation
- 1991-04-12 DK DK91908255.2T patent/DK0532515T3/da active
- 1991-04-12 PL PL91297179A patent/PL168236B1/pl unknown
- 1991-04-12 BR BR919106518A patent/BR9106518A/pt not_active Application Discontinuation
- 1991-04-12 AU AU77703/91A patent/AU648558B2/en not_active Ceased
- 1991-05-24 IL IL11301191A patent/IL113011A/xx not_active IP Right Cessation
- 1991-05-24 IL IL9825691A patent/IL98256A/en not_active IP Right Cessation
- 1991-05-29 PT PT97796A patent/PT97796B/pt not_active IP Right Cessation
- 1991-05-29 MY MYPI91000939A patent/MY107819A/en unknown
- 1991-05-30 ZA ZA914133A patent/ZA914133B/xx unknown
- 1991-05-30 NZ NZ238340A patent/NZ238340A/xx unknown
- 1991-05-30 NZ NZ250217A patent/NZ250217A/en unknown
- 1991-05-30 CZ CS911623A patent/CZ284663B6/cs not_active IP Right Cessation
- 1991-05-30 CN CN91103654A patent/CN1037768C/zh not_active Expired - Fee Related
- 1991-05-30 IE IE184191A patent/IE911841A1/en not_active IP Right Cessation
- 1991-05-30 YU YU96291A patent/YU48030B/sh unknown
1992
- 1992-11-27 FI FI925415A patent/FI101376B/fi active
- 1992-11-27 NO NO924598A patent/NO180083C/no not_active IP Right Cessation
1994
- 1994-12-26 JP JP6322305A patent/JP2549609B2/ja not_active Expired - Fee Related
1995
- 1995-03-16 IL IL11301195A patent/IL113011A0/xx unknown
1996
- 1996-12-18 GR GR960403524T patent/GR3022079T3/el unknown
1997
- 1997-08-26 CN CNB971178879A patent/CN1154636C/zh not_active Expired - Fee Related

Also Published As

Publication number	Publication date
NO924598L (no)	1992-11-27
EP0532515A1 (en)	1993-03-24
IL113011A0 (en)	1995-06-29
ES2093099T3 (es)	1996-12-16
YU96291A (sh)	1994-06-10
KR0160142B1 (ko)	1998-12-01
YU48030B (sh)	1996-10-09
CA2080249A1 (en)	1991-12-01
JPH07206819A (ja)	1995-08-08
FI925415A0 (fi)	1992-11-27
NZ238340A (en)	1994-06-27
NO180083B (no)	1996-11-04
IL113011A (en)	1999-09-22
GR3022079T3 (en)	1997-03-31
PL168236B1 (pl)	1996-01-31
DE69122866D1 (de)	1996-11-28
MY107819A (en)	1996-06-29
JPH05502238A (ja)	1993-04-22
EP0532515B1 (en)	1996-10-23
IE911841A1 (en)	1991-12-04
CA2080249C (en)	1996-11-19
FI101376B1 (fi)	1998-06-15
WO1991018878A1 (en)	1991-12-12
IL98256A (en)	1995-11-27
FI925415L (fi)	1992-11-27
CN1154636C (zh)	2004-06-23
IL98256A0 (en)	1992-06-21
ZA914133B (en)	1993-01-27
HU226529B1 (en)	2009-03-30
JP2549609B2 (ja)	1996-10-30
DE69122866T2 (de)	1997-02-20
FI101376B (fi)	1998-06-15
HUT68166A (en)	1995-05-29
CS162391A3 (en)	1992-02-19
PT97796B (pt)	1998-10-30
CZ284663B6 (cs)	1999-01-13
AU648558B2 (en)	1994-04-28
CN1037768C (zh)	1998-03-18
CN1183408A (zh)	1998-06-03
PL169187B1 (pl)	1996-06-28
CN1056876A (zh)	1991-12-11
AU7770391A (en)	1991-12-31
HU9203761D0 (en)	1993-03-29
JPH0794439B2 (ja)	1995-10-11
ATE144498T1 (de)	1996-11-15
NZ250217A (en)	1995-05-26
KR930700443A (ko)	1993-03-15
NO180083C (no)	1997-02-12
PT97796A (pt)	1992-02-28
RU2077531C1 (ru)	1997-04-20
NO924598D0 (no)	1992-11-27
BR9106518A (pt)	1993-05-25

Publication	Publication Date	Title
DK0532515T3 (da)	1997-04-21	Fremstilling af substituerede piperidiner
FI964520L (fi)	1996-11-11	Atsabisykloyhdisteet
DK0563345T3 (da)	2002-10-14	Nye 4-arylpiperaziner og 4-arylpiperidiner
DK0619806T3 (da)	1996-02-05	Fremstilling af substituerede piperidiner
DK0450420T3 (da)	1995-02-20	Heterocyclisk substituerede dihydropyridiner, fremgangsmåde til deres fremstilling og deres anvendelse i lægemidler
DE69100517D1 (de)	1993-11-25	Polyethyleneiminphosphonatderivate als Dispergiermittel enthaltende Zementzusammensetzungen.
PT98268A (pt)	1992-05-29	Processo para a preparacao de indano-pirrolidino-carbamatos
DK0623620T3 (da)	1999-06-07	5-HT3-pyrrolopyrazinderivater
SE8601344L (sv)	1986-03-21	Derivat av 11-desoxi-17alfa-hydroxikortikosteron
DK0418990T3 (da)	1994-03-14	13-brom- og 13,14-dibrom-ergoliner, deres fremstilling og anvendelse i lægemidler
DE59002172D1 (de)	1993-09-09	Neue 1,3-oxazine.
DK0582977T3 (da)	1996-12-16	Fremgangsmåde til fremstilling af 1,3-dialkyl-5-hydroxyoxindoler og etherderivater deraf
DK0555283T3 (da)	1995-07-03	Mellemprodukter ved fremstillingen af 4,5-difluoranthranilinsyre