DE69931975D1 - FSH Mimetika zur Behandlung von Infertilität - Google Patents
FSH Mimetika zur Behandlung von InfertilitätInfo
- Publication number
- DE69931975D1 DE69931975D1 DE69931975T DE69931975T DE69931975D1 DE 69931975 D1 DE69931975 D1 DE 69931975D1 DE 69931975 T DE69931975 T DE 69931975T DE 69931975 T DE69931975 T DE 69931975T DE 69931975 D1 DE69931975 D1 DE 69931975D1
- Authority
- DE
- Germany
- Prior art keywords
- infertility
- treatment
- fsh mimetics
- fsh
- mimetics
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 208000000509 infertility Diseases 0.000 title 1
- 230000036512 infertility Effects 0.000 title 1
- 231100000535 infertility Toxicity 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Diabetes (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9571298P | 1998-08-07 | 1998-08-07 | |
| US95712P | 1998-08-07 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69931975D1 true DE69931975D1 (de) | 2006-07-27 |
| DE69931975T2 DE69931975T2 (de) | 2006-10-05 |
Family
ID=22253270
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69931975T Expired - Lifetime DE69931975T2 (de) | 1998-08-07 | 1999-08-05 | FSH Mimetika zur Behandlung von Infertilität |
| DE69921147T Expired - Lifetime DE69921147T2 (de) | 1998-08-07 | 1999-08-05 | Fsh mimetika zur behandlung von infertilität |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69921147T Expired - Lifetime DE69921147T2 (de) | 1998-08-07 | 1999-08-05 | Fsh mimetika zur behandlung von infertilität |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US6235755B1 (de) |
| EP (1) | EP1102763B1 (de) |
| JP (1) | JP4511042B2 (de) |
| AR (1) | AR021755A1 (de) |
| AT (2) | ATE279407T1 (de) |
| AU (1) | AU772373B2 (de) |
| CA (1) | CA2339018A1 (de) |
| DE (2) | DE69931975T2 (de) |
| ES (2) | ES2228084T3 (de) |
| IL (1) | IL141063A (de) |
| PT (2) | PT1102763E (de) |
| WO (1) | WO2000008015A2 (de) |
Families Citing this family (76)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6025355A (en) * | 1997-05-19 | 2000-02-15 | Cambridge Neuroscience, Inc. | Pharmaceutically active compounds and methods of use |
| EP1156803A4 (de) | 1999-02-09 | 2004-03-17 | Bristol Myers Squibb Co | LACTAM INHIBITOREN DES FXa UND METHODE |
| HK1054031B (zh) * | 2000-03-27 | 2007-05-04 | Merck Serono Sa | 具有药物活性的吡咯烷衍生物 |
| PT1268418E (pt) * | 2000-03-27 | 2006-08-31 | Applied Research Systems | Derivados da pirrolidina farmacologicamente activos com inibidores bax |
| GB0010757D0 (en) | 2000-05-05 | 2000-06-28 | Astrazeneca Ab | Chemical compounds |
| US6511973B2 (en) | 2000-08-02 | 2003-01-28 | Bristol-Myers Squibb Co. | Lactam inhibitors of FXa and method |
| IL156811A0 (en) * | 2001-01-19 | 2004-02-08 | Pharmacopeia Inc | Bisaryl derivatives and pharmaceutical compositions containing the same |
| US6900213B2 (en) | 2001-01-19 | 2005-05-31 | Pharmacopeia Drug Discovery, Inc. | Bisaryl derivatives having FSH modulatory activity |
| DE60210944T3 (de) | 2001-02-23 | 2015-07-23 | Merck Sharp & Dohme Corp. | N-substituierte nichtaryl-heterocyclische nmda/nr2b antagonisten |
| JP2005511478A (ja) | 2001-04-03 | 2005-04-28 | メルク エンド カムパニー インコーポレーテッド | N−置換非アリール複素環アミジル系nmda/nr2b拮抗薬 |
| CA2446396A1 (en) * | 2001-05-05 | 2002-11-14 | Smithkline Beecham P.L.C. | N-aroyl cyclic amines |
| GB0115862D0 (en) * | 2001-06-28 | 2001-08-22 | Smithkline Beecham Plc | Compounds |
| JP4523273B2 (ja) | 2001-07-02 | 2010-08-11 | ナームローゼ・フエンノートチヤツプ・オルガノン | テトラヒドロキノリン誘導体 |
| GB0121941D0 (en) | 2001-09-11 | 2001-10-31 | Astrazeneca Ab | Chemical compounds |
| IL161235A0 (en) * | 2001-10-22 | 2004-09-27 | Applied Research Systems | Fsh composition, its preparation and use |
| US7754722B2 (en) * | 2002-09-20 | 2010-07-13 | Merck Serono Sa | Piperazine derivatives and methods of use |
| CN100386318C (zh) * | 2002-12-20 | 2008-05-07 | 欧加农股份有限公司 | 四氢喹啉衍生物及其作为fsh受体调节剂的用途 |
| TWI306855B (en) * | 2002-12-20 | 2009-03-01 | Organon Nv | Tetrahydroquinoline derivatives |
| TWI322012B (en) * | 2002-12-20 | 2010-03-21 | Organon Nv | Tetrahydroquinoline derivatives |
| CN100404508C (zh) * | 2002-12-20 | 2008-07-23 | 欧加农股份有限公司 | 四氢喹啉衍生物 |
| UA88879C2 (en) * | 2003-09-02 | 2009-12-10 | Эплайд Рисерч Системз Эрс Холдинг Н.В. | Fsh glycosylation mutant |
| EP1711610A2 (de) * | 2004-01-28 | 2006-10-18 | Syntonix Pharmaceuticals, Inc. | Heterodimere follikel-stimulierendes-hormon-fc (fsh-fc)-fusionsproteine zur behandlung von unfruchtbarkeit |
| US7691848B2 (en) | 2005-03-02 | 2010-04-06 | Wyeth | Pyrrolobenzodiazepine arylcarboxamides and derivatives thereof as follicle-stimulating hormone receptor antagonists |
| JPWO2006095922A1 (ja) * | 2005-03-10 | 2008-08-21 | 京都薬品工業株式会社 | テトラヒドロイソキノリン化合物およびその医薬用途 |
| UA92008C2 (en) | 2005-05-04 | 2010-09-27 | Н.В. Органон | 4-PHENYL-5-OXO-l,4,5,6,7,8-HEXAHYDROQUINOLINE DERIVATIVES AS MEDICAMENTS FOR THE TREATMENT OF INFERTILITY |
| UA92009C2 (ru) | 2005-05-04 | 2010-09-27 | Н.В. Органон | Производные 4-фенил-5-оксо-1,4,5,6,7,8-гексагидрохинолина для лечения бесплодия |
| UA92007C2 (ru) | 2005-05-04 | 2010-09-27 | Н.В. Органон | Производные 4-фенил-5-оксо-1,4,5,6,7,8-гексагидрохинолина для лечения бесплодности |
| PT1879866E (pt) | 2005-05-04 | 2011-06-01 | Organon Nv | Derivados de di-hidropiridina |
| MX2007014085A (es) | 2005-05-12 | 2008-02-07 | Wyeth Corp | Pirrolobenzodiazepinas y derivados de carboxamida heterociclica como antagonistas de receptor de hormona estimulante del foliculo. |
| WO2006135687A1 (en) | 2005-06-09 | 2006-12-21 | Wyeth | Pyrrolobenzodiazepine pyridine carboxamides and derivatives as follicle-stimulating hormone receptor antagonists |
| US20090018142A9 (en) * | 2006-05-02 | 2009-01-15 | Zhengping Zhuang | Use of phosphatases to treat tumors overexpressing N-CoR |
| AU2007254165A1 (en) * | 2006-05-17 | 2007-11-29 | Forschungsverbund Berlin E.V. | Pyrimidine low molecular weight ligands for modulating hormone receptors |
| JP5448164B2 (ja) | 2006-07-28 | 2014-03-19 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Cb2受容体を変調する化合物 |
| AU2008214299B2 (en) * | 2007-02-06 | 2014-01-09 | Lixte Biotechnology, Inc. | Oxabicycloheptanes and oxabicycloheptenes, their preparation and use |
| MX2010003417A (es) * | 2007-10-01 | 2010-09-10 | Lixte Biotechnology Inc | Inhibidores de histona desacetilasa. |
| WO2009061652A1 (en) | 2007-11-07 | 2009-05-14 | Boehringer Ingelheim International Gmbh | Compounds which modulate the cb2 receptor |
| TW200944523A (en) * | 2008-02-08 | 2009-11-01 | Organon Nv | (Dihydro)pyrrolo[2,1-a]isoquinolines |
| WO2010005782A1 (en) | 2008-07-10 | 2010-01-14 | Boehringer Ingelheim International Gmbh | Sulfone compounds which modulate the cb2 receptor |
| EP2318005B1 (de) | 2008-08-01 | 2017-11-01 | Lixte Biotechnology, Inc. | Neuroprotektive mittel zur verhinderung und behandlung von neurodegenerativen erkrankungen |
| US8227473B2 (en) | 2008-08-01 | 2012-07-24 | Lixte Biotechnology, Inc. | Oxabicycloheptanes and oxabicycloheptenes, their preparation and use |
| WO2010147612A1 (en) | 2009-06-18 | 2010-12-23 | Lixte Biotechnology, Inc. | Methods of modulating cell regulation by inhibiting p53 |
| AP2011005674A0 (en) | 2008-09-25 | 2011-04-30 | Boehringer Ingelheim Int | Sulfonyl compounds which selectively modulate the CB2 receptor. |
| WO2010083328A2 (en) | 2009-01-14 | 2010-07-22 | The Salk Institute For Biological Studies | Methods for screening and compounds that protect against amyloid diseases |
| WO2010096371A2 (en) | 2009-02-18 | 2010-08-26 | Boehringer Ingelheim International Gmbh | Heterocyclic compounds which modulate the cb2 receptor |
| US8071587B2 (en) | 2009-05-27 | 2011-12-06 | N. V. Organon | (Dihydro)imidazoiso[5,1-A]quinolines |
| TWI461426B (zh) * | 2009-05-27 | 2014-11-21 | Merck Sharp & Dohme | (二氫)咪唑並異〔5,1-a〕喹啉類 |
| US8299103B2 (en) | 2009-06-15 | 2012-10-30 | Boehringer Ingelheim International Gmbh | Compounds which selectively modulate the CB2 receptor |
| US8383615B2 (en) | 2009-06-16 | 2013-02-26 | Boehringer Ingelheim International Gmbh | Azetidine 2-carboxamide derivatives which modulate the CB2 receptor |
| TW201116531A (en) | 2009-07-29 | 2011-05-16 | Organon Nv | Ring-annulated dihydropyrrolo[2,1-a]isoquinolines |
| US8431564B2 (en) | 2009-07-29 | 2013-04-30 | Merck Sharp & Dohme B.V. | Ring-annulated dihydropyrrolo[2,1-α]isoquinolines |
| TW201116515A (en) | 2009-07-31 | 2011-05-16 | Organon Nv | Dihydrobenzoindazoles |
| SG178948A1 (en) | 2009-09-01 | 2012-04-27 | Catabasis Pharmaceuticals Inc | Fatty acid niacin conjugates and their uses |
| USRE46608E1 (en) | 2009-09-01 | 2017-11-14 | Catabasis Pharmaceuticals, Inc. | Fatty acid niacin conjugates and their uses |
| US8383651B2 (en) | 2009-09-22 | 2013-02-26 | Boehringer Ingelheim International Gmbh | Compounds which selectively modulate the CB2 receptor |
| EP2523936A1 (de) | 2010-01-15 | 2012-11-21 | Boehringer Ingelheim International GmbH | Cb2 rezeptor-modulierende verbindungen |
| US8329735B2 (en) | 2010-03-05 | 2012-12-11 | Boehringer Ingelheim International Gmbh | Tetrazole compounds which selectively modulate the CB2 receptor |
| EP2595959B1 (de) | 2010-07-22 | 2015-11-04 | Boehringer Ingelheim International GmbH | Sulfonylverbindungen zur modulierung des cb2-rezeptors |
| ES2796774T3 (es) * | 2011-07-01 | 2020-11-30 | Merck Patent Gmbh | Dihidropirazoles, composiciones farmacéuticas de los mismos y su uso para el tratamiento de trastornos de fertilidad |
| CA2834199C (en) | 2011-07-18 | 2020-01-07 | Merck Patent Gmbh | Benzamides as allosteric modulators of the fsh receptor |
| CN104080784B (zh) * | 2012-01-10 | 2017-07-18 | 默克专利有限公司 | 用作卵泡刺激素调节剂的苯甲酰胺衍生物 |
| BR112014019351A8 (pt) | 2012-02-08 | 2017-07-11 | Merck Patent Gmbh | Análogos de tiazolidinona deuterados como agonistas para o receptor do hormônio folículo estimulante |
| EP2983661B1 (de) | 2013-04-09 | 2024-05-29 | Lixte Biotechnology, Inc. | Formulierungen von oxabicycloheptanen und oxabicycloheptenen |
| EP2803668A1 (de) | 2013-05-17 | 2014-11-19 | Boehringer Ingelheim International Gmbh | Neuartige (Cyano-dimethyl-methyl)-isoxazole und -[1,3,4]-thiadiazole |
| CA2912921C (en) | 2013-06-24 | 2021-05-18 | Merck Patent Gmbh | Pyrazole compounds as modulators of fshr and uses thereof |
| EP3013823B1 (de) | 2013-06-24 | 2017-11-01 | Merck Patent GmbH | Imidazolverbindungen als modulatoren von fshr und verwendungen davon |
| US11433047B2 (en) | 2015-10-09 | 2022-09-06 | Neurotheryx Canada Ltd. | Pharmaceutical compositions comprising one or more pyrone compounds, and their use for treating inflammatory and neurodegenerative diseases |
| WO2018107004A1 (en) | 2016-12-08 | 2018-06-14 | Lixte Biotechnology, Inc. | Oxabicycloheptanes for modulation of immune response |
| WO2019084037A1 (en) | 2017-10-26 | 2019-05-02 | University Of Puerto Rico | NOVEL CARBAZOLE EHOP-016 DERIVATIVES AS ANTICANCER AGENTS AND ANTI-MIGRATORY AGENTS |
| PH12022550932A1 (en) | 2019-10-25 | 2023-06-14 | Gilead Sciences Inc | Glp-1r modulating compounds |
| KR102863043B1 (ko) | 2020-01-29 | 2025-09-23 | 길리애드 사이언시즈, 인코포레이티드 | Glp-1r 조절 화합물 |
| WO2022109182A1 (en) | 2020-11-20 | 2022-05-27 | Gilead Sciences, Inc. | Polyheterocyclic glp-1 r modulating compounds |
| US12091404B2 (en) | 2021-03-11 | 2024-09-17 | Gilead Sciences, Inc. | GLP-1R modulating compounds |
| WO2022192430A1 (en) | 2021-03-11 | 2022-09-15 | Gilead Sciences, Inc. | Glp-1r modulating compounds |
| PH12023552860A1 (en) | 2021-04-21 | 2024-05-20 | Gilead Sciences Inc | Carboxy-benzimidazole glp-1r modulating compounds |
| KR20250157379A (ko) | 2023-03-08 | 2025-11-04 | 훼링 비.브이. | 소분자 fsh 수용체 조절제 |
| CN117510475A (zh) * | 2023-11-01 | 2024-02-06 | 江苏缘龙医院管理有限责任公司 | 干扰RNA-蛋白相互作用的Musashi蛋白抑制剂及其应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3947569A (en) * | 1972-04-12 | 1976-03-30 | American Home Products Corporation | Process for preparing the releasing hormone of luteinizing hormone (LH) and of follicle stimulating hormone (FSH), salts and compositions thereof, and intermediates therefor |
| JPS5331669A (en) * | 1976-09-06 | 1978-03-25 | Kissei Pharmaceut Co Ltd | Novel n-acylpiperidinecaroxyanilide derivatives and their preparation |
| US4800432A (en) * | 1986-10-24 | 1989-01-24 | The Grass Valley Group, Inc. | Video Difference key generator |
| DE3636278A1 (de) * | 1986-10-24 | 1988-05-05 | Hoechst Ag | Herbizide mittel auf der basis von cyclischen (alpha)-iminocarbon-saeureaniliden sowie neue (alpha)-iminocarbonsaeureanilide und verfahren zu ihrer herstellung |
| US5071823A (en) | 1988-10-12 | 1991-12-10 | Mitsubishi Paper Mills Limited | Image-receiving sheet for transfer recording |
| DE3842010A1 (de) * | 1988-12-14 | 1990-06-21 | Hoechst Ag | Kompetitive gonadoliberin-antagonisten |
| EP0610487B1 (de) * | 1992-09-03 | 1999-11-10 | Boehringer Ingelheim Pharma KG | Neue aminosäurederivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende pharmazeutische zusammensetzungen |
| US5455229A (en) * | 1992-12-23 | 1995-10-03 | Eli Lilly And Company | Method for minimizing and containing ischemic and reperfusion injury |
| PE45195A1 (es) * | 1994-03-03 | 1996-01-17 | Boehringer Ingelheim Kg | Derivado de aminoacido, procedimiento para su preparacion y composicion farmaceutica que lo contiene |
| JP2002505318A (ja) * | 1998-03-05 | 2002-02-19 | アゴーロン・ファーマシューティカルズ・インコーポレイテッド | 非ペプチドGnRH因子 |
-
1999
- 1999-08-05 CA CA002339018A patent/CA2339018A1/en not_active Abandoned
- 1999-08-05 US US09/369,222 patent/US6235755B1/en not_active Expired - Lifetime
- 1999-08-05 IL IL14106399A patent/IL141063A/xx not_active IP Right Cessation
- 1999-08-05 EP EP99939686A patent/EP1102763B1/de not_active Expired - Lifetime
- 1999-08-05 WO PCT/US1999/017755 patent/WO2000008015A2/en not_active Ceased
- 1999-08-05 DE DE69931975T patent/DE69931975T2/de not_active Expired - Lifetime
- 1999-08-05 ES ES99939686T patent/ES2228084T3/es not_active Expired - Lifetime
- 1999-08-05 ES ES03023514T patent/ES2261844T3/es not_active Expired - Lifetime
- 1999-08-05 DE DE69921147T patent/DE69921147T2/de not_active Expired - Lifetime
- 1999-08-05 AT AT99939686T patent/ATE279407T1/de active
- 1999-08-05 JP JP2000563648A patent/JP4511042B2/ja not_active Expired - Fee Related
- 1999-08-05 PT PT99939686T patent/PT1102763E/pt unknown
- 1999-08-05 AT AT03023514T patent/ATE329911T1/de active
- 1999-08-05 AU AU53931/99A patent/AU772373B2/en not_active Ceased
- 1999-08-06 AR ARP990103937A patent/AR021755A1/es active IP Right Grant
- 1999-08-08 PT PT03023514T patent/PT1380582E/pt unknown
-
2000
- 2000-11-28 US US09/723,495 patent/US6423723B1/en not_active Expired - Fee Related
-
2002
- 2002-05-28 US US10/156,431 patent/US6653338B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US6653338B2 (en) | 2003-11-25 |
| DE69921147D1 (de) | 2004-11-18 |
| JP4511042B2 (ja) | 2010-07-28 |
| IL141063A0 (en) | 2002-02-10 |
| CA2339018A1 (en) | 2000-02-17 |
| US6235755B1 (en) | 2001-05-22 |
| JP2002522433A (ja) | 2002-07-23 |
| EP1102763B1 (de) | 2004-10-13 |
| AU5393199A (en) | 2000-02-28 |
| US6423723B1 (en) | 2002-07-23 |
| WO2000008015A2 (en) | 2000-02-17 |
| AU772373B2 (en) | 2004-04-22 |
| DE69921147T2 (de) | 2005-02-24 |
| DE69931975T2 (de) | 2006-10-05 |
| ES2261844T3 (es) | 2006-11-16 |
| ATE329911T1 (de) | 2006-07-15 |
| AR021755A1 (es) | 2002-08-07 |
| PT1102763E (pt) | 2005-01-31 |
| EP1102763A2 (de) | 2001-05-30 |
| PT1380582E (pt) | 2006-08-31 |
| US20020147345A1 (en) | 2002-10-10 |
| IL141063A (en) | 2005-06-19 |
| ES2228084T3 (es) | 2005-04-01 |
| WO2000008015A3 (en) | 2000-05-11 |
| ATE279407T1 (de) | 2004-10-15 |
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Owner name: LABORATOIRES SERONO S.A., COINSINS, VAUD, CH |