DE60320388D1 - Assay mit dissoziativer fluoreszenzverstärkung - Google Patents
Assay mit dissoziativer fluoreszenzverstärkungInfo
- Publication number
- DE60320388D1 DE60320388D1 DE60320388T DE60320388T DE60320388D1 DE 60320388 D1 DE60320388 D1 DE 60320388D1 DE 60320388 T DE60320388 T DE 60320388T DE 60320388 T DE60320388 T DE 60320388T DE 60320388 D1 DE60320388 D1 DE 60320388D1
- Authority
- DE
- Germany
- Prior art keywords
- sub
- assay
- enhancement
- dissociative
- dissociative fluorescence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000003556 assay Methods 0.000 title abstract 3
- 238000001514 detection method Methods 0.000 abstract 2
- 229910021644 lanthanide ion Inorganic materials 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 125000001153 fluoro group Chemical group F* 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/682—Signal amplification
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/80—Fluorescent dyes, e.g. rhodamine
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/108331—Preservative, buffer, anticoagulant or diluent
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/15—Inorganic acid or base [e.g., hcl, sulfuric acid, etc. ]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/20—Oxygen containing
- Y10T436/200833—Carbonyl, ether, aldehyde or ketone containing
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Zoology (AREA)
- Cell Biology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Pyrane Compounds (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US93034 | 2002-03-08 | ||
| US10/093,034 US7211440B2 (en) | 2002-03-08 | 2002-03-08 | Dissociative fluorescence enhancement assay |
| PCT/FI2003/000145 WO2003076939A1 (en) | 2002-03-08 | 2003-02-28 | Dissociative fluorescence enhancement assay |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60320388D1 true DE60320388D1 (de) | 2008-05-29 |
| DE60320388T2 DE60320388T2 (de) | 2009-05-28 |
Family
ID=27804193
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60320388T Expired - Lifetime DE60320388T2 (de) | 2002-03-08 | 2003-02-28 | Assay mit dissoziativer fluoreszenzverstärkung |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US7211440B2 (de) |
| EP (1) | EP1483582B1 (de) |
| JP (1) | JP4339696B2 (de) |
| CN (1) | CN100350250C (de) |
| AT (1) | ATE392616T1 (de) |
| AU (1) | AU2003212393A1 (de) |
| CA (1) | CA2477385C (de) |
| DE (1) | DE60320388T2 (de) |
| ES (1) | ES2305446T3 (de) |
| WO (1) | WO2003076939A1 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7482444B2 (en) | 2006-03-13 | 2009-01-27 | Wallac Oy | Terminating substrates for DNA polymerases |
| WO2011137325A2 (en) * | 2010-04-30 | 2011-11-03 | Pharmaseq, Inc. | Metal nanoparticle structures for enhancing fluorescence-based assays |
| US20130231468A1 (en) * | 2010-11-22 | 2013-09-05 | Takeshi Yamashita | Rare earth metal complex |
| US20150094234A1 (en) * | 2012-04-23 | 2015-04-02 | Aqsens Oy | Method for characterizing and/or determining samples |
| CN103674912B (zh) * | 2013-12-03 | 2016-01-27 | 齐齐哈尔大学 | 吡啶季铵盐阳离子表面活性剂的荧光检测方法及其应用 |
| CN103969432B (zh) * | 2014-03-27 | 2016-02-17 | 中国科学院福建物质结构研究所 | 一种稀土纳米材料溶解增强时间分辨荧光免疫分析方法 |
| CN117327105A (zh) * | 2023-12-01 | 2024-01-02 | 浙江大学 | 一种稀土配合物荧光微球、制备方法及其应用 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE425439B (sv) | 1981-04-30 | 1982-09-27 | Wallac Oy | Immunologisk analys med lantanidkelatkomplex som markor |
| SE8301395L (sv) | 1983-03-15 | 1984-09-16 | Wallac Oy | Kelatiserande foreningar med funktionella grupper vilka tillater kovalent koppling till bio-organiska molekyler |
| GB8622855D0 (en) | 1986-09-23 | 1986-10-29 | Ekins R P | Determining biological substance |
| SE8702824L (sv) | 1987-07-10 | 1989-01-11 | Wallac Oy | Metall-kelaterande 2,6-disubstituerade pyridinfoereningar och deras anvaendning |
| SE8703682L (sv) | 1987-09-24 | 1989-03-25 | Wallac Oy | Homogen bestaemningsmetod som utnyttjar affinitetsreaktioner |
| WO1989004375A1 (en) | 1987-10-23 | 1989-05-18 | Siska Diagnostics, Inc. | Lanthanide chelate-tagged nucleic acid probes |
| US6127529A (en) | 1988-06-29 | 2000-10-03 | Wallac Oy | Metal-chelating 2,6-disubstituted pyridine compounds and their use |
| FI88654C (fi) | 1991-03-15 | 1993-06-10 | Datacity Center Oy | Fluorescenshoejningsmetod |
| US6429026B1 (en) * | 1996-04-08 | 2002-08-06 | Innotrac Diagnostics Oy | One-step all-in-one dry reagent immunoassay |
| FI963989L (fi) | 1996-10-04 | 1998-04-05 | Wallac Oy | Homogeenisiä määritysmenetelmiä, jotka perustuvat luminesenssienergiasiirtoon |
| JP2000019171A (ja) * | 1998-04-28 | 2000-01-21 | Kazuko Matsumoto | 標識プローブによる分析方法 |
| US6030840A (en) | 1998-06-15 | 2000-02-29 | Nen Life Sciences, Inc. | Neutral enhancement of lanthanides for time resolved fluorescence |
| IL146055A0 (en) | 1999-04-23 | 2002-07-25 | Alza Corp | Conjugate having a cleavable linkage for use in a liposome |
| US6329205B1 (en) * | 1999-08-31 | 2001-12-11 | Molecular Probes, Inc. | Detection method using luminescent europium-based protein stains |
| WO2001039675A1 (en) | 1999-12-01 | 2001-06-07 | Aesthetic Technologies, Inc. | Skin abrasion system and method |
| CN1108280C (zh) * | 2000-09-18 | 2003-05-14 | 中国建筑材料科学研究院 | 混凝土高活性细钢渣粉掺合料及制备混凝土的方法 |
| DE10127208A1 (de) | 2001-06-05 | 2002-12-12 | Basf Ag | Polyurethanispersionen und deren Verwendung |
| DE60233742D1 (de) * | 2001-10-10 | 2009-10-29 | Hitachi High Tech Corp | Leuchtverbindungen und markierungsreagentien für die diese verwendet werden |
-
2002
- 2002-03-08 US US10/093,034 patent/US7211440B2/en not_active Expired - Lifetime
-
2003
- 2003-02-28 CA CA2477385A patent/CA2477385C/en not_active Expired - Lifetime
- 2003-02-28 JP JP2003575112A patent/JP4339696B2/ja not_active Expired - Fee Related
- 2003-02-28 EP EP03708289A patent/EP1483582B1/de not_active Expired - Lifetime
- 2003-02-28 AT AT03708289T patent/ATE392616T1/de not_active IP Right Cessation
- 2003-02-28 AU AU2003212393A patent/AU2003212393A1/en not_active Abandoned
- 2003-02-28 CN CNB038093448A patent/CN100350250C/zh not_active Expired - Lifetime
- 2003-02-28 ES ES03708289T patent/ES2305446T3/es not_active Expired - Lifetime
- 2003-02-28 DE DE60320388T patent/DE60320388T2/de not_active Expired - Lifetime
- 2003-02-28 WO PCT/FI2003/000145 patent/WO2003076939A1/en not_active Ceased
-
2006
- 2006-09-07 US US11/516,740 patent/US7381567B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ATE392616T1 (de) | 2008-05-15 |
| US7211440B2 (en) | 2007-05-01 |
| DE60320388T2 (de) | 2009-05-28 |
| ES2305446T3 (es) | 2008-11-01 |
| CN100350250C (zh) | 2007-11-21 |
| US20030170907A1 (en) | 2003-09-11 |
| US7381567B2 (en) | 2008-06-03 |
| AU2003212393A1 (en) | 2003-09-22 |
| WO2003076939A1 (en) | 2003-09-18 |
| CA2477385A1 (en) | 2003-09-18 |
| CN1650165A (zh) | 2005-08-03 |
| JP4339696B2 (ja) | 2009-10-07 |
| EP1483582A1 (de) | 2004-12-08 |
| JP2005519305A (ja) | 2005-06-30 |
| EP1483582B1 (de) | 2008-04-16 |
| CA2477385C (en) | 2011-08-09 |
| US20070015284A1 (en) | 2007-01-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |