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DK0915851T3 - Dibenzodihydropyridincarboxyl-estre og deres anvendelse i kemiluminiscens-analyse-fremgangsmåder - Google Patents

Dibenzodihydropyridincarboxyl-estre og deres anvendelse i kemiluminiscens-analyse-fremgangsmåder

Info

Publication number
DK0915851T3
DK0915851T3 DK97930881T DK97930881T DK0915851T3 DK 0915851 T3 DK0915851 T3 DK 0915851T3 DK 97930881 T DK97930881 T DK 97930881T DK 97930881 T DK97930881 T DK 97930881T DK 0915851 T3 DK0915851 T3 DK 0915851T3
Authority
DK
Denmark
Prior art keywords
alkyl
pct
aryl
dibenzodihydropyridine
substituted
Prior art date
Application number
DK97930881T
Other languages
English (en)
Inventor
Marjorie Jacquemijns
Gijsbert Zomer
Original Assignee
Nederlanden Staat
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nederlanden Staat filed Critical Nederlanden Staat
Application granted granted Critical
Publication of DK0915851T3 publication Critical patent/DK0915851T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04Ortho- or peri-condensed ring systems
    • C07D221/06Ring systems of three rings
    • C07D221/10Aza-phenanthrenes
    • C07D221/12Phenanthridines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D219/00Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C12Q1/28Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving peroxidase
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/968High energy substrates, e.g. fluorescent, chemiluminescent, radioactive
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/975Kit

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Cosmetics (AREA)
DK97930881T 1996-07-16 1997-07-15 Dibenzodihydropyridincarboxyl-estre og deres anvendelse i kemiluminiscens-analyse-fremgangsmåder DK0915851T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP96202022 1996-07-16
PCT/NL1997/000417 WO1998002421A1 (en) 1996-07-16 1997-07-15 Dibenzodihydropyridinecarboxylic esters and their use in chemiluminescent assay methods

Publications (1)

Publication Number Publication Date
DK0915851T3 true DK0915851T3 (da) 2002-04-29

Family

ID=8224199

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97930881T DK0915851T3 (da) 1996-07-16 1997-07-15 Dibenzodihydropyridincarboxyl-estre og deres anvendelse i kemiluminiscens-analyse-fremgangsmåder

Country Status (10)

Country Link
US (1) US6030803A (da)
EP (1) EP0915851B1 (da)
JP (1) JP3338061B2 (da)
AT (1) ATE214697T1 (da)
CA (1) CA2261032C (da)
DE (1) DE69711188T2 (da)
DK (1) DK0915851T3 (da)
ES (1) ES2171964T3 (da)
PT (1) PT915851E (da)
WO (1) WO1998002421A1 (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6410732B2 (en) 1996-01-16 2002-06-25 Lumigen, Inc. Processing and synthetic intermediates for preparing N-arylacridancarboxylic acid derivatives
WO1997026245A1 (en) 1996-01-16 1997-07-24 Lumigen, Inc. Compounds, compositions and methods for generating chemiluminescence with phosphatase enzymes
DE69940433D1 (de) 1998-08-11 2009-04-02 Siemens Healthcare Diagnostics Im nahen infrarot chemilumineszente akridinium derivate und ihre verwendung
US7186568B1 (en) 2000-06-26 2007-03-06 Lumigen Inc. Electrochemiluminescence from acridan compounds
US6897036B2 (en) * 2002-06-06 2005-05-24 Lumigen, Inc. Fluorescent detection of peroxidase enzymes
US7319041B2 (en) * 2002-09-27 2008-01-15 Siemens Medical Solutions Diagnostic Applications of acridinium compounds and derivatives in homogeneous assays
US7309615B2 (en) 2002-09-27 2007-12-18 Siemens Medical Solutions Diagnostic High quantum yield acridinium compounds and their uses in improving assay sensitivity
US7799534B2 (en) 2006-05-09 2010-09-21 Beckman Coulter, Inc. Nonseparation assay methods
US7732153B2 (en) 2006-05-09 2010-06-08 Beckman Coulter, Inc. Nonseparation assay methods
EP2997976A1 (en) 2007-07-27 2016-03-23 Armagen Technologies, Inc. Methods and compositions for increasing alpha-l-iduronidase activity in the cns
US20100240070A1 (en) * 2007-11-07 2010-09-23 Beckman Coulter, Inc. Nonseparation Assay Methods Using Peroxide Generating Enzymes
BRPI1008760B1 (pt) 2009-02-27 2019-12-10 Beckman Coulter Inc método de ensaio e kit para um analito em uma amostra e sistema para realizar o método de ensaio
CA2753596A1 (en) * 2009-02-27 2010-09-02 Beckman Coulter, Inc. Non separation assays with selective signal inhibitors
US20110097723A1 (en) * 2009-09-19 2011-04-28 Qun Liu Methods and reagents for analyte detection
EP2485761B1 (en) 2009-10-09 2019-02-27 Armagen, Inc. Methods and compositions for increasing iduronate 2-sulfatase activity in the cns
WO2012028167A2 (en) 2010-05-20 2012-03-08 Innohyphen Bv Acridinium ester chemiluminescence upon reductive triggering
CN104230804B (zh) * 2014-08-30 2016-05-25 云南民族大学 化学发光物aps-5关键中间体的制备方法
US10538589B2 (en) 2015-01-14 2020-01-21 Armagen Inc. Methods and compositions for increasing N-acetylglucosaminidase (NAGLU) activity in the CNS using a fusion antibody comprising an anti-human insulin receptor antibody and NAGLU
JP2021531458A (ja) 2018-07-13 2021-11-18 スリーエム イノベイティブ プロパティズ カンパニー アッセイ
US11320424B2 (en) 2018-07-13 2022-05-03 3M Innovative Properties Company Specific binding chemiluminescent assay

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3628573C2 (de) * 1986-08-22 1994-10-13 Hoechst Ag Chemilumineszierende Acridinderivate, Verfahren zu deren Herstellung und ihre Verwendung in Lumineszenzimmunoassays
NZ227506A (en) * 1987-12-31 1992-06-25 London Diagnostics Inc Specific binding assays using chemiluminescent compounds
US4950613A (en) * 1988-02-26 1990-08-21 Gen-Probe Incorporated Proteted chemiluminescent labels
JP2859451B2 (ja) * 1991-01-11 1999-02-17 太平洋セメント株式会社 N−フルオロピリジニウム塩の製造方法
US5491072A (en) * 1993-05-17 1996-02-13 Lumigen, Inc. N-alkylacridan carboxyl derivatives useful for chemiluminescent detection

Also Published As

Publication number Publication date
US6030803A (en) 2000-02-29
PT915851E (pt) 2002-09-30
CA2261032C (en) 2003-11-25
EP0915851A1 (en) 1999-05-19
DE69711188D1 (de) 2002-04-25
JP3338061B2 (ja) 2002-10-28
JPH11514006A (ja) 1999-11-30
CA2261032A1 (en) 1998-01-22
ES2171964T3 (es) 2002-09-16
WO1998002421A1 (en) 1998-01-22
DE69711188T2 (de) 2002-09-05
ATE214697T1 (de) 2002-04-15
EP0915851B1 (en) 2002-03-20

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