DE69923580D1 - Verstärkte katalysierte reporterabscheidung - Google Patents
Verstärkte katalysierte reporterabscheidungInfo
- Publication number
- DE69923580D1 DE69923580D1 DE69923580T DE69923580T DE69923580D1 DE 69923580 D1 DE69923580 D1 DE 69923580D1 DE 69923580 T DE69923580 T DE 69923580T DE 69923580 T DE69923580 T DE 69923580T DE 69923580 D1 DE69923580 D1 DE 69923580D1
- Authority
- DE
- Germany
- Prior art keywords
- cooh
- reinforced
- enhancing
- heteroatom alkyl
- inorganic salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 230000008021 deposition Effects 0.000 title 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 3
- 230000002708 enhancing effect Effects 0.000 abstract 3
- 102000003992 Peroxidases Human genes 0.000 abstract 2
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 abstract 2
- 229910052799 carbon Inorganic materials 0.000 abstract 2
- 239000003153 chemical reaction reagent Substances 0.000 abstract 2
- 229910017053 inorganic salt Inorganic materials 0.000 abstract 2
- 150000002894 organic compounds Chemical class 0.000 abstract 2
- 125000001626 borono group Chemical group [H]OB([*])O[H] 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 239000000758 substrate Substances 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
- C12Q1/28—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving peroxidase
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C235/18—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the singly-bound oxygen atoms further bound to a carbon atom of a six-membered aromatic ring, e.g. phenoxyacetamides
- C07C235/20—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the singly-bound oxygen atoms further bound to a carbon atom of a six-membered aromatic ring, e.g. phenoxyacetamides having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Luminescent Compositions (AREA)
- Carbon And Carbon Compounds (AREA)
- Reinforced Plastic Materials (AREA)
- Inert Electrodes (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10765498P | 1998-11-09 | 1998-11-09 | |
| US107654P | 1998-11-09 | ||
| US09/434,742 US6372937B1 (en) | 1998-11-09 | 1999-11-05 | Enhanced catalyzed reporter deposition |
| US434742 | 1999-11-05 | ||
| PCT/US1999/026327 WO2000028077A1 (en) | 1998-11-09 | 1999-11-08 | Enhanced catalyzed reporter deposition |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69923580D1 true DE69923580D1 (de) | 2005-03-10 |
| DE69923580T2 DE69923580T2 (de) | 2006-01-05 |
Family
ID=26805004
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69923580T Expired - Lifetime DE69923580T2 (de) | 1998-11-09 | 1999-11-08 | Verstärkte katalysierte reporterabscheidung |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US6372937B1 (de) |
| EP (1) | EP1129214B1 (de) |
| AT (1) | ATE288497T1 (de) |
| AU (1) | AU768695B2 (de) |
| CA (1) | CA2351579C (de) |
| DE (1) | DE69923580T2 (de) |
| ES (1) | ES2237184T3 (de) |
| WO (1) | WO2000028077A1 (de) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9400034D0 (sv) * | 1994-01-06 | 1994-01-06 | Glycorex Ab | Laktosaminderivat |
| US6518036B1 (en) * | 1999-03-17 | 2003-02-11 | Nen Life Science Products, Inc. | Method of permanent fluorescent assay |
| JP2002280842A (ja) * | 2001-03-21 | 2002-09-27 | Hitachi Ltd | 電力増幅器モジュール |
| JP2004535792A (ja) * | 2001-04-27 | 2004-12-02 | ザ ジェネラル ホスピタル コーポレーション | チロシナーゼアッセイ法 |
| US6617125B2 (en) * | 2001-06-29 | 2003-09-09 | Perkinelmer Life Sciences, Inc. | Compositions for enhanced catalyzed reporter deposition |
| US20090163375A1 (en) | 2003-09-09 | 2009-06-25 | Bowman Christopher N | Use of Photopolymerization for Amplification and Detection of a Molecular Recognition Event |
| US7354706B2 (en) * | 2003-09-09 | 2008-04-08 | The Regents Of The University Of Colorado, A Body Corporate | Use of photopolymerization for amplification and detection of a molecular recognition event |
| PL209602B1 (pl) | 2005-10-20 | 2011-09-30 | Inst Chemii Bioorg Pan | Sposób otrzymywania amidu kwasu 3-(4-hydroksyfenylo)propanowego |
| JP5639889B2 (ja) | 2007-09-18 | 2014-12-10 | ダコ デンマーク アクティーゼルスカブ | 生物学的標的の高速で高感度な検出方法 |
| US20090137405A1 (en) * | 2007-11-16 | 2009-05-28 | Christopher Bowman | Detection of nucleic acid biomarkers using polymerization-based amplification |
| US8435735B2 (en) * | 2009-02-19 | 2013-05-07 | Dako Denmark A/S | Methods and compounds for detection of molecular targets |
| CN104714007B (zh) * | 2009-10-20 | 2017-04-12 | 丹麦达科有限公司 | 单个靶实体的免疫化学检测 |
| JP2013531801A (ja) | 2010-07-02 | 2013-08-08 | ヴェンタナ メディカル システムズ， インク． | 標的検出のためのハプテンコンジュゲート |
| ES2689593T3 (es) | 2010-12-30 | 2018-11-14 | Ventana Medical Systems, Inc. | Depósito potenciado de cromógenos que utilizan análogos de piridina |
| JP6101782B2 (ja) | 2012-03-27 | 2017-03-22 | ヴェンタナ メディカル システムズ， インク． | シグナリングコンジュゲート及び使用法 |
| AU2015326827B2 (en) | 2014-10-02 | 2019-11-07 | Ventana Medical Systems, Inc. | Polymers and conjugates comprising the same |
| AU2016349644B2 (en) | 2015-11-06 | 2022-11-24 | Ventana Medical Systems, Inc. | Representative diagnostics |
| US11691141B2 (en) | 2017-11-13 | 2023-07-04 | Roche Sequencing Solutions, Inc. | Devices for sample analysis using epitachophoresis |
| CN112789684B (zh) | 2018-10-01 | 2025-05-09 | 文塔纳医疗系统公司 | 用于预测对pd-1轴导向疗法的应答的方法和系统 |
| WO2020074742A1 (en) | 2018-10-12 | 2020-04-16 | F. Hoffmann-La Roche Ag | Detection methods for epitachophoresis workflow automation |
| EP3969583A1 (de) | 2019-05-14 | 2022-03-23 | F. Hoffmann-La Roche AG | Vorrichtungen und verfahren zur probenanalyse |
| US12281355B2 (en) | 2019-09-30 | 2025-04-22 | Akoya Biosciences, Inc. | Multiplexed imaging with enzyme mediated amplification |
| WO2025137702A1 (en) | 2023-12-21 | 2025-06-26 | Akoya Biosciences, Inc. | Spatially resolved cyclic multiplexed detection of nucleic acids and proteins in tissue |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4521511A (en) | 1982-09-22 | 1985-06-04 | Enzyme Technology Company | Catalyzed colorimetric and fluorometric substrates for peroxidase enzyme determinations |
| EP0116454B1 (de) | 1983-02-11 | 1987-04-29 | National Research Development Corporation | Erhöhte lumineszierende oder luminometrische Prüfung |
| GB8420053D0 (en) | 1984-08-07 | 1984-09-12 | Secr Social Service Brit | Enhanced luminescent/luminometric assay |
| US4835101A (en) | 1986-02-10 | 1989-05-30 | Kallestad Diagnostics, Inc. | Luminescent analyses with enhanced storage stability |
| US5196306A (en) | 1989-03-29 | 1993-03-23 | E. I. Du Pont De Nemours And Company | Method for the detection or quantitation of an analyte using an analyte dependent enzyme activation system |
| US5629168A (en) | 1992-02-10 | 1997-05-13 | British Technology Group Limited | Chemiluminescent enhancers |
| US5688966A (en) | 1996-07-26 | 1997-11-18 | E. I. Du Pont De Nemours And Company | Compounds and method for synthesizing sulfoindocyanine dyes |
| US5863748A (en) | 1997-03-14 | 1999-01-26 | New Life Science Products, Inc. | p-Hydroxycinnamoyl-containing substrates for an analyte dependent enzyme activation system |
| US6518036B1 (en) * | 1999-03-17 | 2003-02-11 | Nen Life Science Products, Inc. | Method of permanent fluorescent assay |
-
1999
- 1999-11-05 US US09/434,742 patent/US6372937B1/en not_active Expired - Lifetime
- 1999-11-08 ES ES99958831T patent/ES2237184T3/es not_active Expired - Lifetime
- 1999-11-08 CA CA002351579A patent/CA2351579C/en not_active Expired - Lifetime
- 1999-11-08 DE DE69923580T patent/DE69923580T2/de not_active Expired - Lifetime
- 1999-11-08 WO PCT/US1999/026327 patent/WO2000028077A1/en not_active Ceased
- 1999-11-08 AU AU16115/00A patent/AU768695B2/en not_active Expired
- 1999-11-08 EP EP99958831A patent/EP1129214B1/de not_active Expired - Lifetime
- 1999-11-08 AT AT99958831T patent/ATE288497T1/de not_active IP Right Cessation
-
2001
- 2001-05-17 US US09/859,988 patent/US6593100B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ES2237184T3 (es) | 2005-07-16 |
| CA2351579C (en) | 2010-01-19 |
| EP1129214A4 (de) | 2002-06-19 |
| EP1129214B1 (de) | 2005-02-02 |
| CA2351579A1 (en) | 2000-05-18 |
| DE69923580T2 (de) | 2006-01-05 |
| US6593100B2 (en) | 2003-07-15 |
| EP1129214A1 (de) | 2001-09-05 |
| AU768695B2 (en) | 2004-01-08 |
| US20010039035A1 (en) | 2001-11-08 |
| US6372937B1 (en) | 2002-04-16 |
| AU1611500A (en) | 2000-05-29 |
| WO2000028077A1 (en) | 2000-05-18 |
| ATE288497T1 (de) | 2005-02-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |