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DE602005016818D1 - Verfahren zur charakterisierung einer polyklonalen zellinie - Google Patents

Verfahren zur charakterisierung einer polyklonalen zellinie

Info

Publication number
DE602005016818D1
DE602005016818D1 DE602005016818T DE602005016818T DE602005016818D1 DE 602005016818 D1 DE602005016818 D1 DE 602005016818D1 DE 602005016818 T DE602005016818 T DE 602005016818T DE 602005016818 T DE602005016818 T DE 602005016818T DE 602005016818 D1 DE602005016818 D1 DE 602005016818D1
Authority
DE
Germany
Prior art keywords
cell line
polyclonal
platform
polyclonal cell
characterizing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE602005016818T
Other languages
English (en)
Inventor
Lone Kjar Rasmussen
Torben Frandsen
Soeren Kofoed Rasmussen
Peter Sejer Andersen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Symphogen AS
Original Assignee
Symphogen AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Symphogen AS filed Critical Symphogen AS
Publication of DE602005016818D1 publication Critical patent/DE602005016818D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/96—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation using ion-exchange
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Document Processing Apparatus (AREA)
DE602005016818T 2004-07-20 2005-07-20 Verfahren zur charakterisierung einer polyklonalen zellinie Expired - Lifetime DE602005016818D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA200401133 2004-07-20
DKPA200401991 2004-12-22
PCT/DK2005/000504 WO2006007853A2 (en) 2004-07-20 2005-07-20 A procedure for structural characterization of a recombinant polyclonal protein or a polyclonal cell line

Publications (1)

Publication Number Publication Date
DE602005016818D1 true DE602005016818D1 (de) 2009-11-05

Family

ID=35427551

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602005016818T Expired - Lifetime DE602005016818D1 (de) 2004-07-20 2005-07-20 Verfahren zur charakterisierung einer polyklonalen zellinie

Country Status (18)

Country Link
US (2) US8288109B2 (de)
EP (2) EP2053408B1 (de)
JP (1) JP4870667B2 (de)
KR (1) KR101319848B1 (de)
AT (2) ATE443870T1 (de)
AU (1) AU2005263334C1 (de)
BR (1) BRPI0513714A (de)
CA (1) CA2574146C (de)
DE (1) DE602005016818D1 (de)
DK (2) DK1787126T3 (de)
ES (2) ES2332524T3 (de)
IL (2) IL180169A (de)
MX (1) MX2007000551A (de)
NO (1) NO20070931L (de)
NZ (1) NZ552264A (de)
PL (2) PL2053408T3 (de)
RU (1) RU2426795C2 (de)
WO (1) WO2006007853A2 (de)

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PT1583830E (pt) 2003-01-07 2006-11-30 Symphogen As Método para produzir proteínas policlonais recombinantes
TWI333977B (en) 2003-09-18 2010-12-01 Symphogen As Method for linking sequences of interest
BRPI0513706A (pt) 2004-07-20 2008-05-13 Symphogen As anticorpo policlonal recombinante anti-rhesus d e métodos de produção
ES2332524T3 (es) 2004-07-20 2010-02-08 Symphogen A/S Un procedimiento para la caracterizacion de una linea celular policlonal.
JP2009518320A (ja) * 2005-12-05 2009-05-07 シュムフォウエン アクティーゼルスカブ 抗オルトポックスウイルス組換えポリクローナル抗体
US8338376B2 (en) 2006-10-20 2012-12-25 Biogen Idec Ma Inc. Compositions comprising variant LT-B-R-IG fusion proteins
WO2008112325A2 (en) * 2007-03-15 2008-09-18 Biogen Idec Ma Inc. Treatment of autoimmune disorders
RU2459868C2 (ru) * 2007-03-01 2012-08-27 Симфоген А/С Способ клонирования когнатных антител
CN104151430A (zh) * 2007-03-01 2014-11-19 西福根有限公司 重组抗表皮生长因子受体抗体组合物
CN101679513A (zh) * 2007-03-06 2010-03-24 西福根有限公司 用于治疗呼吸道合胞病毒感染的重组抗体
EP2152872B1 (de) 2007-05-25 2010-09-15 Symphogen A/S Verfahren zur herstellung eines rekombinanten polyklonalen proteins
JP2008289483A (ja) * 2007-05-25 2008-12-04 Symphogen As 真核生物系において発現可能な形質転換体のスクリーニング
CA2695309A1 (en) * 2007-09-07 2009-03-12 Symphogen A/S Methods for recombinant manufacturing of anti-rsv antibodies
CN101874207A (zh) * 2007-11-22 2010-10-27 西福根有限公司 用于表征重组多克隆蛋白质的方法
JP2011518790A (ja) * 2008-04-23 2011-06-30 シムフォゲン・アクティーゼルスカブ ポリクローナルタンパク質を製造する方法
EP2331689A4 (de) * 2008-08-29 2012-10-31 Symphogen As Verfahren zum klonen von antikörpern aus vögeln
EP2331577B1 (de) 2008-08-29 2017-06-07 Symphogen A/S Zusammensetzungen rekombinanter antikörper gegen den rezeptor des epidermalen wachstumsfaktors
US8821879B2 (en) 2009-09-04 2014-09-02 Xoma Technology Ltd. Anti-botulism antibody coformulations
US20120264155A1 (en) * 2009-10-09 2012-10-18 Symphogen A/S Multiplex Quantitation of Individual Recombinant Proteins in a Mixture by Signature Peptides and Mass Spectrometry
US8987419B2 (en) * 2010-04-15 2015-03-24 AbbVie Deutschland GmbH & Co. KG Amyloid-beta binding proteins
EP2635605B1 (de) 2010-11-01 2018-07-25 Symphogen A/S Antikörper gegen her3 und zusammensetzungen daraus
US9790269B2 (en) 2013-02-08 2017-10-17 Misfolding Diagnostics, Inc. Transthyretin antibodies and uses thereof
EP3729958B1 (de) * 2013-03-15 2023-05-03 Mayo Foundation for Medical Education and Research Identifizierung und überwachung von monoklonalen immunglobulinen nach molekülmasse
UY35517A (es) 2013-04-04 2014-10-31 Mabxience S A Un procedimiento para aumentar la formación de ácido piroglutamico de una proteína
WO2015093925A1 (es) * 2013-12-19 2015-06-25 CASTRO ALDRETE, Jorge Isaac Método de producción de anticuerpos específicos
TW201623331A (zh) * 2014-03-12 2016-07-01 普羅帝納生物科學公司 抗黑色素瘤細胞黏著分子（ｍｃａｍ）抗體類及使用彼等之相關方法
WO2018031887A1 (en) * 2016-08-12 2018-02-15 Abreos Biosciences, Inc. Detection and quantification of natalizumab
GB201710691D0 (en) * 2017-07-04 2017-08-16 Ge Healthcare Bio Sciences Ab Method in bioprocess purification system
CN112513074A (zh) * 2018-06-22 2021-03-16 健玛保 生产两种或更多种不同抗体的受控混合物的方法
CN112816595A (zh) * 2021-01-06 2021-05-18 海默斯（重庆）医学生物技术有限公司 一种重组角蛋白液体制剂及其纯度检测方法
WO2025038736A1 (en) * 2023-08-15 2025-02-20 Gigagen, Inc. Methods of analyzing recombinant polyclonal proteins

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Also Published As

Publication number Publication date
EP2053408B1 (de) 2012-03-07
ATE443870T1 (de) 2009-10-15
ES2332524T3 (es) 2010-02-08
AU2005263334A1 (en) 2006-01-26
EP2053408A3 (de) 2009-07-29
MX2007000551A (es) 2007-03-30
WO2006007853A2 (en) 2006-01-26
AU2005263334C1 (en) 2011-01-20
DK1787126T3 (da) 2009-12-21
US20130203063A1 (en) 2013-08-08
IL203017A (en) 2013-08-29
AU2005263334B2 (en) 2010-08-05
JP2008506960A (ja) 2008-03-06
EP2053408A2 (de) 2009-04-29
WO2006007853A3 (en) 2006-05-18
CA2574146C (en) 2015-06-30
JP4870667B2 (ja) 2012-02-08
HK1133076A1 (en) 2010-03-12
EP1787126B1 (de) 2009-09-23
US20080131882A1 (en) 2008-06-05
IL180169A0 (en) 2007-06-03
PL2053408T3 (pl) 2012-08-31
BRPI0513714A (pt) 2008-05-13
ES2381531T3 (es) 2012-05-29
RU2426795C2 (ru) 2011-08-20
KR101319848B1 (ko) 2013-10-18
DK2053408T3 (da) 2012-06-04
NZ552264A (en) 2010-03-26
HK1101043A1 (en) 2007-10-05
RU2007106050A (ru) 2008-08-27
ATE548657T1 (de) 2012-03-15
US8288109B2 (en) 2012-10-16
NO20070931L (no) 2007-04-17
CA2574146A1 (en) 2006-01-26
PL1787126T3 (pl) 2010-03-31
KR20070032078A (ko) 2007-03-20
US9029091B2 (en) 2015-05-12
IL180169A (en) 2011-04-28
EP1787126A2 (de) 2007-05-23

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