DK0920509T3 - Polypeptider, der er i stand til at danne antigenbindende strukturer med specificitet for Rhesus D-antigener, DNA, der koder herfor, samt fremgangsmåde til fremstilling heraf og anvendelse heraf - Google Patents

Polypeptider, der er i stand til at danne antigenbindende strukturer med specificitet for Rhesus D-antigener, DNA, der koder herfor, samt fremgangsmåde til fremstilling heraf og anvendelse heraf

Info

Publication number: DK0920509T3
Authority: DK; Denmark
Prior art keywords: rhesus; preparation; antigen binding; antigens; specificity
Prior art date: 1996-06-24

Application number

DK97929244T

Other languages

English (en)

Inventor

Sylvia Miescher

Monique Vogel

Beda Stadler

Andreas Morell

Martin Imboden

Hanspeter Amstutz

Original Assignee

Zlb Behring Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-06-24

Filing date

1997-06-20

Publication date

2004-12-06

1997-06-20 Application filed by Zlb Behring Ag filed Critical Zlb Behring Ag

2004-12-06 Application granted granted Critical

2004-12-06 Publication of DK0920509T3 publication Critical patent/DK0920509T3/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/80—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood groups or blood types or red blood cells
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/34—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood group antigens
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S424/00—Drug, bio-affecting and body treating compositions
- Y10S424/80—Antibody or fragment thereof whose amino acid sequence is disclosed in whole or in part
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S424/00—Drug, bio-affecting and body treating compositions
- Y10S424/81—Drug, bio-affecting and body treating compositions involving autoimmunity, allergy, immediate hypersensitivity, delayed hypersensitivity, immunosuppression, immunotolerance, or anergy
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/868—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof involving autoimmunity, allergy, immediate hypersensitivity, delayed hypersensitivity, immunosuppression, or immunotolerance

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Immunology (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Hematology (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Biomedical Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
Biophysics (AREA)
Microbiology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biotechnology (AREA)
Urology & Nephrology (AREA)
Physics & Mathematics (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Food Science & Technology (AREA)
Mycology (AREA)
Analytical Chemistry (AREA)
Cell Biology (AREA)
General Physics & Mathematics (AREA)
Pathology (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
General Engineering & Computer Science (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
Gastroenterology & Hepatology (AREA)
General Chemical & Material Sciences (AREA)
Plant Pathology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Diabetes (AREA)

DK97929244T 1996-06-24 1997-06-20 Polypeptider, der er i stand til at danne antigenbindende strukturer med specificitet for Rhesus D-antigener, DNA, der koder herfor, samt fremgangsmåde til fremstilling heraf og anvendelse heraf DK0920509T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP96810421		1996-06-24
EP97929244A EP0920509B1 (en)	1996-06-24	1997-06-20	Polypeptides capable of forming antigen binding structures with specificity for the rhesus d antigens, the dna encoding them and the process for their preparation and use

Publications (1)

Publication Number	Publication Date
DK0920509T3 true DK0920509T3 (da)	2004-12-06

Family

ID=8225636

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK97929244T DK0920509T3 (da)	1996-06-24	1997-06-20	Polypeptider, der er i stand til at danne antigenbindende strukturer med specificitet for Rhesus D-antigener, DNA, der koder herfor, samt fremgangsmåde til fremstilling heraf og anvendelse heraf

Country Status (23)

Country	Link
US (3)	US7038020B1 (da)
EP (1)	EP0920509B1 (da)
JP (1)	JP3841360B2 (da)
KR (1)	KR100361449B1 (da)
AT (1)	ATE272116T1 (da)
AU (1)	AU722127B2 (da)
BG (1)	BG64534B1 (da)
BR (1)	BR9709958A (da)
CA (1)	CA2258494C (da)
CZ (1)	CZ296807B6 (da)
DE (1)	DE69730031T2 (da)
DK (1)	DK0920509T3 (da)
ES (1)	ES2224255T3 (da)
HU (1)	HUP9902605A3 (da)
IL (1)	IL127595A (da)
IS (1)	IS2220B (da)
NO (1)	NO327947B1 (da)
NZ (1)	NZ333329A (da)
PL (1)	PL186019B1 (da)
RU (1)	RU2204602C2 (da)
SK (1)	SK284879B6 (da)
TR (1)	TR199802692T2 (da)
WO (1)	WO1997049809A1 (da)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2002530080A (ja) *	1998-11-19	2002-09-17	インサイト・ファーマスーティカルズ・インコーポレイテッド	免疫グロブリン・スーパーファミリー・タンパク質
EP1106625A1 (en) *	1999-11-17	2001-06-13	ZLB Bioplasma AG	Rhesus D specific peptide sequences
FR2807767B1 (fr)	2000-04-12	2005-01-14	Lab Francais Du Fractionnement	Anticorps monoclonaux anti-d
CA2406236C (en) *	2000-04-17	2013-02-19	Dyax Corp.	Novel methods of constructing libraries of genetic packages that collectively display the members of a diverse family of peptides, polypeptides or proteins
US8288322B2 (en)	2000-04-17	2012-10-16	Dyax Corp.	Methods of constructing libraries comprising displayed and/or expressed members of a diverse family of peptides, polypeptides or proteins and the novel libraries
WO2002046435A2 (en) *	2000-12-05	2002-06-13	Alexion Pharmaceuticals, Inc.	Engineered plasmids and their use for in situ production of genes
DE60144063D1 (de)	2000-12-18	2011-03-31	Dyax Corp	Gerichtete bibliotheken die genetisch verpackt sind
AU2016225923B2 (en) *	2001-04-17	2018-07-05	Takeda Pharmaceutical Company Limited	Novel Methods of Constructing Libraries Comprising Displayed and/or Expressed Members of a Diverse Family of Peptides, Polypeptides or Proteins and the Novel Libraries
RU2209434C1 (ru) *	2001-11-15	2003-07-27	Российский центр судебно-медицинской экспертизы Министерства здравоохранения Российской Федерации	Способ получения резус-пептидов анти-d, специфически выявляющих антиген rhd в следах крови и выделений
US20040067532A1 (en)	2002-08-12	2004-04-08	Genetastix Corporation	High throughput generation and affinity maturation of humanized antibody
RU2426795C2 (ru)	2004-07-20	2011-08-20	Симфоген А/С	Способ структурной характеристики рекомбинантного поликлонального белка или поликлональной клеточной линии
BRPI0513706A (pt) *	2004-07-20	2008-05-13	Symphogen As	anticorpo policlonal recombinante anti-rhesus d e métodos de produção
GB0706558D0 (en) *	2007-04-03	2007-05-09	Common Services Agency For The	Diagnostic assay
US8877688B2 (en)	2007-09-14	2014-11-04	Adimab, Llc	Rationally designed, synthetic antibody libraries and uses therefor
CA2697193C (en)	2007-09-14	2017-06-06	Adimab, Inc.	Rationally designed, synthetic antibody libraries and uses therefor
EP2045602A1 (en)	2007-10-04	2009-04-08	Symphogen A/S	Potency assay
US9873957B2 (en)	2008-03-13	2018-01-23	Dyax Corp.	Libraries of genetic packages comprising novel HC CDR3 designs
CA3049612C (en)	2008-04-24	2023-01-10	Dyax Corp.	Libraries of genetic packages comprising novel hc cdr1, cdr2, and cdr3 and novel lc cdr1, cdr2, and cdr3 designs
WO2012009568A2 (en)	2010-07-16	2012-01-19	Adimab, Llc	Antibody libraries
EP2917236A2 (en) *	2012-11-06	2015-09-16	MedImmune, LLC	Combination therapies using anti-pseudomonas psl and pcrv binding molecules
CN111247170B (zh) *	2017-10-20	2024-07-16	杰特有限公司	一种方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB2127434A (en)	1982-09-17	1984-04-11	Univ London	A human monoclonal antibody against Rhesus D antigen
GB8722018D0 (en) *	1987-09-18	1987-10-28	Central Blood Lab Authority	Human anti-rh(d)monoclonal antibodies
GB8925590D0 (en)	1989-11-13	1990-01-04	Central Blood Lab Authority	Monoclonal antibodies

1997
- 1997-06-20 EP EP97929244A patent/EP0920509B1/en not_active Expired - Lifetime
- 1997-06-20 CZ CZ0395998A patent/CZ296807B6/cs not_active IP Right Cessation
- 1997-06-20 JP JP50232398A patent/JP3841360B2/ja not_active Expired - Lifetime
- 1997-06-20 SK SK1761-98A patent/SK284879B6/sk not_active IP Right Cessation
- 1997-06-20 KR KR10-1998-0710975A patent/KR100361449B1/ko not_active Expired - Fee Related
- 1997-06-20 RU RU99101121/13A patent/RU2204602C2/ru not_active IP Right Cessation
- 1997-06-20 DK DK97929244T patent/DK0920509T3/da active
- 1997-06-20 ES ES97929244T patent/ES2224255T3/es not_active Expired - Lifetime
- 1997-06-20 PL PL97330794A patent/PL186019B1/pl not_active IP Right Cessation
- 1997-06-20 DE DE69730031T patent/DE69730031T2/de not_active Expired - Lifetime
- 1997-06-20 WO PCT/EP1997/003253 patent/WO1997049809A1/en not_active Ceased
- 1997-06-20 IL IL12759597A patent/IL127595A/xx not_active IP Right Cessation
- 1997-06-20 CA CA002258494A patent/CA2258494C/en not_active Expired - Fee Related
- 1997-06-20 NZ NZ333329A patent/NZ333329A/xx not_active IP Right Cessation
- 1997-06-20 TR TR1998/02692T patent/TR199802692T2/xx unknown
- 1997-06-20 HU HU9902605A patent/HUP9902605A3/hu unknown
- 1997-06-20 AU AU33423/97A patent/AU722127B2/en not_active Expired
- 1997-06-20 AT AT97929244T patent/ATE272116T1/de active
- 1997-06-20 BR BR9709958A patent/BR9709958A/pt not_active Application Discontinuation
- 1997-06-20 US US09/147,443 patent/US7038020B1/en not_active Expired - Fee Related
1998
- 1998-12-11 IS IS4922A patent/IS2220B/is unknown
- 1998-12-15 BG BG103016A patent/BG64534B1/bg unknown
- 1998-12-23 NO NO19986088A patent/NO327947B1/no not_active IP Right Cessation
2005
- 2005-06-20 US US11/155,775 patent/US7399471B2/en not_active Expired - Fee Related
2006
- 2006-01-18 US US11/333,197 patent/US7429647B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
BR9709958A (pt)	1999-08-10
HUP9902605A3 (en)	2001-11-28
SK284879B6 (sk)	2006-01-05
TR199802692T2 (xx)	1999-03-22
HUP9902605A2 (hu)	1999-11-29
EP0920509B1 (en)	2004-07-28
RU2204602C2 (ru)	2003-05-20
PL186019B1 (pl)	2003-09-30
US20050266013A1 (en)	2005-12-01
CA2258494C (en)	2008-05-27
BG103016A (en)	1999-08-31
EP0920509A1 (en)	1999-06-09
IL127595A (en)	2005-09-25
SK176198A3 (en)	1999-07-12
US7399471B2 (en)	2008-07-15
NO327947B1 (no)	2009-10-26
US20060165694A1 (en)	2006-07-27
JP3841360B2 (ja)	2006-11-01
CA2258494A1 (en)	1997-12-31
KR100361449B1 (ko)	2003-01-24
ES2224255T3 (es)	2005-03-01
IS2220B (is)	2007-03-15
KR20000022530A (ko)	2000-04-25
IL127595A0 (en)	1999-10-28
US7429647B2 (en)	2008-09-30
IS4922A (is)	1998-12-11
NO986088L (no)	1999-02-24
NZ333329A (en)	2000-07-28
DE69730031D1 (de)	2004-09-02
ATE272116T1 (de)	2004-08-15
US7038020B1 (en)	2006-05-02
WO1997049809A1 (en)	1997-12-31
PL330794A1 (en)	1999-06-07
DE69730031T2 (de)	2005-06-16
JP2000515732A (ja)	2000-11-28
CZ296807B6 (cs)	2006-06-14
BG64534B1 (bg)	2005-06-30
AU3342397A (en)	1998-01-14
AU722127B2 (en)	2000-07-20
NO986088D0 (no)	1998-12-23
CZ395998A3 (cs)	1999-05-12

Publication	Publication Date	Title
DK0920509T3 (da)	2004-12-06	Polypeptider, der er i stand til at danne antigenbindende strukturer med specificitet for Rhesus D-antigener, DNA, der koder herfor, samt fremgangsmåde til fremstilling heraf og anvendelse heraf
TR199801722T2 (xx)	1998-12-21	Peptit imm�nojenler.
WO1998050547A3 (en)	1999-03-11	Human toll-like receptor proteins, related reagents and methods
NZ236511A (en)	1993-02-25	Polypeptides containing sequences from residues 61 to 82 or 104 to 129 of human il-4 or subsequences thereof; antibodies and pharmaceutical compositions
GR3030141T3 (en)	1999-08-31	Diphtheria toxin receptor-binding region.
PT100637A (pt)	1994-05-31	Receptor ctla4 e metodos para a sua utilizacao
DE68918867D1 (de)	1994-11-17	Mutanten des hiv-1 Hüllproteins mit fehlenden hypervariabelen domänen.
BR9810907A (pt)	2000-08-01	Anticorpos monoclonais e policlonais, peptìdeo suscetìvel de gerar um anticorpo, agente imunogênico, sequência de nucleotìdeos, composição farmacêutica, uso de pelo menos um anticorpo, kit de diagnóstico, e, processo para preparar um agente imunogênico
EP1433792A8 (en)	2004-10-06	Human receptor proteins, related reagents and methods
DK0500659T3 (da)	1997-07-14	Monoklonale antistoffer.
DE69638024D1 (de)	2009-10-22	Melanoma antigene p15 und deren anwendung in diagnostischen und therapeutischen verfahren
WO2001057219A3 (en)	2002-03-07	Mammalian interleukin-1-delta and -epsilon. their use in therapeutic and diagnostic methods
TR200102877T2 (tr)	2002-01-21	İmmünoglobulinin kendi yüksek afinite reseptörüne bağlanmasını inhibe eden antikorlara karşı anti-idiotipik antikorlar.
WO2002051237A3 (en)	2004-02-26	Helicobacter proteins, nucleic acids and uses thereof
WO1999019480A3 (en)	1999-06-24	Human receptor proteins; related reagents and methods
DE68926813D1 (de)	1996-08-14	Von gemeinsamen sequenzen von antigenen und antiidiotypischen antikörpern oder von antikörpern mit spezifizität für die zellulären rezeptoren der antigene abgeleitete immunogene und biologisch aktive peptide
SE9601231D0 (sv)	1996-03-29	Monoclonal antibody
DULINSKAS et al.	1972	DETERMINATION OF THERMALLY INDUCED LOSSES OF PRESTRESSING IN PRETENSIONED BEAMS SUBJECTED TO STEAM CURING