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DE60108394D1 - Sulfonyl-pyrrolidinderivate geeignet für die behandlung von neurologischen krankheiten - Google Patents

Sulfonyl-pyrrolidinderivate geeignet für die behandlung von neurologischen krankheiten

Info

Publication number
DE60108394D1
DE60108394D1 DE60108394T DE60108394T DE60108394D1 DE 60108394 D1 DE60108394 D1 DE 60108394D1 DE 60108394 T DE60108394 T DE 60108394T DE 60108394 T DE60108394 T DE 60108394T DE 60108394 D1 DE60108394 D1 DE 60108394D1
Authority
DE
Germany
Prior art keywords
sulfonyl
treatment
neurological diseases
pyrrolidine derivatives
derivatives suitable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60108394T
Other languages
English (en)
Other versions
DE60108394T2 (de
Inventor
Vincent Mutel
Juergen Wichmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of DE60108394D1 publication Critical patent/DE60108394D1/de
Application granted granted Critical
Publication of DE60108394T2 publication Critical patent/DE60108394T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
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    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/46—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
    • C07D207/48—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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DE60108394T 2000-06-30 2001-06-22 Sulfonyl-pyrrolidinderivate geeignet für die behandlung von neurologischen krankheiten Expired - Fee Related DE60108394T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP00113894 2000-06-30
EP00113894 2000-06-30
PCT/EP2001/007135 WO2002002554A1 (en) 2000-06-30 2001-06-22 Sulfonyl-pyrrolidine derivatives useful for the treatment of neurological disorders

Publications (2)

Publication Number Publication Date
DE60108394D1 true DE60108394D1 (de) 2005-02-17
DE60108394T2 DE60108394T2 (de) 2006-03-02

Family

ID=8169121

Family Applications (1)

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DE60108394T Expired - Fee Related DE60108394T2 (de) 2000-06-30 2001-06-22 Sulfonyl-pyrrolidinderivate geeignet für die behandlung von neurologischen krankheiten

Country Status (34)

Country Link
US (2) US6589978B2 (de)
EP (1) EP1299383B1 (de)
JP (1) JP3994051B2 (de)
KR (1) KR100529423B1 (de)
CN (1) CN1178936C (de)
AR (1) AR029288A1 (de)
AT (1) ATE286895T1 (de)
AU (2) AU2001281877B2 (de)
BR (1) BR0112093A (de)
CA (1) CA2413243A1 (de)
CZ (1) CZ2003280A3 (de)
DE (1) DE60108394T2 (de)
DK (1) DK1299383T3 (de)
EC (1) ECSP024403A (de)
ES (1) ES2234869T3 (de)
HR (1) HRP20021023B1 (de)
HU (1) HUP0301167A3 (de)
IL (2) IL153425A0 (de)
JO (1) JO2384B1 (de)
MA (1) MA26923A1 (de)
MX (1) MXPA02012270A (de)
MY (1) MY126903A (de)
NO (1) NO324218B1 (de)
NZ (1) NZ523025A (de)
PE (1) PE20020103A1 (de)
PL (1) PL360396A1 (de)
PT (1) PT1299383E (de)
RU (1) RU2272026C2 (de)
SI (1) SI1299383T1 (de)
TW (1) TWI265928B (de)
UY (1) UY26812A1 (de)
WO (1) WO2002002554A1 (de)
YU (1) YU99702A (de)
ZA (1) ZA200209966B (de)

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RU2272026C2 (ru) 2006-03-20
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TWI265928B (en) 2006-11-11
JP3994051B2 (ja) 2007-10-17
HRP20021023B1 (en) 2006-08-31
IL153425A0 (en) 2003-07-06
EP1299383A1 (de) 2003-04-09
NO20026263D0 (no) 2002-12-27
CN1440405A (zh) 2003-09-03
AU2001281877B2 (en) 2006-08-31
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PE20020103A1 (es) 2002-02-13
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CA2413243A1 (en) 2002-01-10
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