CY1115685T1 - Φαρμακευτικη συνθεση προς αγωγη εναντι αϋπνιας μεσω υπογλωσσιας χορηγησης - Google Patents
Φαρμακευτικη συνθεση προς αγωγη εναντι αϋπνιας μεσω υπογλωσσιας χορηγησηςInfo
- Publication number
- CY1115685T1 CY1115685T1 CY20141100588T CY141100588T CY1115685T1 CY 1115685 T1 CY1115685 T1 CY 1115685T1 CY 20141100588 T CY20141100588 T CY 20141100588T CY 141100588 T CY141100588 T CY 141100588T CY 1115685 T1 CY1115685 T1 CY 1115685T1
- Authority
- CY
- Cyprus
- Prior art keywords
- pharmaceutical composition
- composition
- insomnia
- composition against
- treatment
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 abstract 4
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 abstract 3
- 206010022437 insomnia Diseases 0.000 abstract 3
- 239000013543 active substance Substances 0.000 abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
- 230000035587 bioadhesion Effects 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000011859 microparticle Substances 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 230000001737 promoting effect Effects 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
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- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/136—Amines having aromatic rings, e.g. ketamine, nortriptyline having the amino group directly attached to the aromatic ring, e.g. benzeneamine
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- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
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- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
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Abstract
Περιγράφεται φαρμακευτική σύνθεση προς αγωγή έναντι αϋπνίας. Η σύνθεση περιλαμβάνει ουσιαστικά ελεύθερο ύδατος, διατεταγμένο μείγμα τουλάχιστον ενός φαρμακευτικώς δραστικού παράγοντα χρήσιμου στην αγωγή έναντι αϋπνίας υπό τη μορφή μικροσωματιδίων τα οποία προσκολλώνται στις επιφάνειες σωματιδίων που δρουν ως φορείς και τα οποία είναι ουσιαστικά πιο ευμεγέθη από τα σωματίδια του δραστικού παράγοντα, ή, παραγόντων, και είναι υδατοδιαλυτά, σε συνδυασμό με παράγοντα προαγωγής της βιοπροσκόλλησης και/ή της προσκόλλησης σε βλεννογόνο. Η εφεύρεση επίσης σχετίζεται με μέθοδο παρασκευής της σύνθεσης και με τη χρήση της σύνθεσης στην αγωγή έναντι αϋπνίας.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9803240A SE9803240D0 (sv) | 1998-09-24 | 1998-09-24 | A pharmaceutical composition having a rapid action |
| EP10001406.7A EP2236132B1 (en) | 1998-09-24 | 1999-09-24 | Pharmaceutical composition for the treatment of insomnia by sublingual administration |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1115685T1 true CY1115685T1 (el) | 2017-01-25 |
Family
ID=20412702
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
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| CY20131100974T CY1114620T1 (el) | 1998-09-24 | 2013-11-04 | Φαρμακευτικη συνθεση προς υπογλωσσια χορηγηση |
| CY20141100588T CY1115685T1 (el) | 1998-09-24 | 2014-08-04 | Φαρμακευτικη συνθεση προς αγωγη εναντι αϋπνιας μεσω υπογλωσσιας χορηγησης |
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| CY20171101261T CY1119644T1 (el) | 1998-09-24 | 2017-11-30 | Φαρμακευτικη συνθεση ταχειας δρασης που περιλαμβανει βουπρενορφινη |
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| CY20171101261T CY1119644T1 (el) | 1998-09-24 | 2017-11-30 | Φαρμακευτικη συνθεση ταχειας δρασης που περιλαμβανει βουπρενορφινη |
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| DE19652268C2 (de) | 1996-12-16 | 2000-06-29 | Lohmann Therapie Syst Lts | Arzneizubereitung für die Freisetzung von Apomorphin in der Mundhöhle |
| FR2758459B1 (fr) * | 1997-01-17 | 1999-05-07 | Pharma Pass | Composition pharmaceutique de fenofibrate presentant une biodisponibilite elevee et son procede de preparation |
| US5968547A (en) * | 1997-02-24 | 1999-10-19 | Euro-Celtique, S.A. | Method of providing sustained analgesia with buprenorphine |
| DE19749724A1 (de) * | 1997-11-11 | 1999-06-10 | Gruenenthal Gmbh | Verwendung einer Kombination aus Opioid und alpha-adrenergem Agonisten in Schmerzmitteln |
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| US6264974B1 (en) * | 1998-07-07 | 2001-07-24 | Salvagnini Italia Spa | Buccal and sublingual administration of physostigmine |
| SE9803239D0 (sv) * | 1998-09-24 | 1998-09-24 | Diabact Ab | Composition for the treatment of acute pain |
| SE9803240D0 (sv) | 1998-09-24 | 1998-09-24 | Diabact Ab | A pharmaceutical composition having a rapid action |
| EP1005863A1 (en) | 1998-12-04 | 2000-06-07 | Synthelabo | Controlled-release dosage forms comprising a short acting hypnotic or a salt thereof |
| WO2001030391A2 (en) | 1999-10-27 | 2001-05-03 | Farmarc Nederland Bv | Pharmaceutical composition containing midazolam |
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| CN1290525A (zh) | 2000-10-10 | 2001-04-11 | 北京万全阳光医药科技有限公司 | 冷冻干燥的扎来普隆速溶口服组合物 |
| US20030035839A1 (en) | 2001-05-15 | 2003-02-20 | Peirce Management, Llc | Pharmaceutical composition for both intraoral and oral administration |
| BR0306843A (pt) | 2002-01-10 | 2004-12-07 | Biovail Lab Inc | Formulações sedativas de não-benzodiazepina |
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| US20040265375A1 (en) | 2003-04-16 | 2004-12-30 | Platteeuw Johannes J. | Orally disintegrating tablets |
-
1998
- 1998-09-24 SE SE9803240A patent/SE9803240D0/xx unknown
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1999
- 1999-09-24 PL PL383971A patent/PL204264B1/pl unknown
- 1999-09-24 CZ CZ2008-315A patent/CZ2008315A3/cs not_active IP Right Cessation
- 1999-09-24 EP EP10001408.3A patent/EP2236133B1/en not_active Expired - Lifetime
- 1999-09-24 PT PT50778752T patent/PT1652518E/pt unknown
- 1999-09-24 CA CA2820588A patent/CA2820588C/en not_active Expired - Lifetime
- 1999-09-24 HU HU0800435A patent/HU230468B1/hu unknown
- 1999-09-24 KR KR1020017003715A patent/KR100760536B1/ko not_active Expired - Lifetime
- 1999-09-24 DK DK10001406.7T patent/DK2236132T3/da active
- 1999-09-24 EP EP05077875.2A patent/EP1652518B1/en not_active Expired - Lifetime
- 1999-09-24 PT PT141750851T patent/PT2805716T/pt unknown
- 1999-09-24 IL IL14213599A patent/IL142135A0/xx not_active IP Right Cessation
- 1999-09-24 CA CA002345121A patent/CA2345121C/en not_active Expired - Lifetime
- 1999-09-24 ES ES10001408.3T patent/ES2498095T3/es not_active Expired - Lifetime
- 1999-09-24 DE DE69936393T patent/DE69936393T2/de not_active Expired - Lifetime
- 1999-09-24 EE EEP200100182A patent/EE04927B1/xx unknown
- 1999-09-24 ES ES10001406.7T patent/ES2507579T3/es not_active Expired - Lifetime
- 1999-09-24 EP EP14175085.1A patent/EP2805716B1/en not_active Revoked
- 1999-09-24 EE EEP200700030A patent/EE05023B1/xx unknown
- 1999-09-24 ES ES14175085.1T patent/ES2644770T3/es not_active Expired - Lifetime
- 1999-09-24 EP EP99952867A patent/EP1115383B1/en not_active Expired - Lifetime
- 1999-09-24 PL PL347126A patent/PL201644B1/pl unknown
- 1999-09-24 WO PCT/SE1999/001687 patent/WO2000016750A1/en not_active Ceased
- 1999-09-24 EP EP10001406.7A patent/EP2236132B1/en not_active Expired - Lifetime
- 1999-09-24 PT PT100014083T patent/PT2236133E/pt unknown
- 1999-09-24 SK SK402-2001A patent/SK283302B6/sk not_active IP Right Cessation
- 1999-09-24 US US09/787,888 patent/US6761910B1/en not_active Expired - Lifetime
- 1999-09-24 NZ NZ510284A patent/NZ510284A/en not_active IP Right Cessation
- 1999-09-24 CN CNB998135453A patent/CN1173694C/zh not_active Expired - Lifetime
- 1999-09-24 ES ES99952867T patent/ES2289829T3/es not_active Expired - Lifetime
- 1999-09-24 TR TR2001/00855T patent/TR200100855T2/xx unknown
- 1999-09-24 PT PT100014067T patent/PT2236132E/pt unknown
- 1999-09-24 AU AU64927/99A patent/AU764346B2/en not_active Expired
- 1999-09-24 DK DK05077875.2T patent/DK1652518T3/da active
- 1999-09-24 CA CA2629988A patent/CA2629988C/en not_active Expired - Lifetime
- 1999-09-24 PT PT99952867T patent/PT1115383E/pt unknown
- 1999-09-24 EE EEP200800028A patent/EE05555B1/xx unknown
- 1999-09-24 DK DK10001408.3T patent/DK2236133T3/da active
- 1999-09-24 DK DK14175085.1T patent/DK2805716T3/en active
- 1999-09-24 MX MXPA01003068A patent/MXPA01003068A/es active IP Right Grant
- 1999-09-24 BR BRPI9913945A patent/BRPI9913945B8/pt not_active IP Right Cessation
- 1999-09-24 AT AT99952867T patent/ATE365540T1/de active
- 1999-09-24 RU RU2001111025/14A patent/RU2193879C1/ru active
- 1999-09-24 JP JP2000573711A patent/JP3381220B2/ja not_active Expired - Lifetime
- 1999-09-24 ES ES05077875T patent/ES2433930T3/es not_active Expired - Lifetime
- 1999-09-24 CZ CZ20011029A patent/CZ302975B6/cs not_active IP Right Cessation
- 1999-09-24 HU HU0103856A patent/HU230342B1/hu unknown
- 1999-09-24 DK DK99952867T patent/DK1115383T3/da active
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2001
- 2001-03-22 NO NO20011473A patent/NO332226B1/no not_active IP Right Cessation
- 2001-03-23 BG BG105379A patent/BG65502B1/bg unknown
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2004
- 2004-05-24 US US10/851,215 patent/US20040213855A1/en not_active Abandoned
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2006
- 2006-10-10 US US11/544,660 patent/US7910132B2/en not_active Expired - Fee Related
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2007
- 2007-08-07 CY CY20071101054T patent/CY1107711T1/el unknown
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2008
- 2008-07-01 US US12/216,197 patent/US20080286368A1/en not_active Abandoned
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2011
- 2011-11-22 US US13/302,694 patent/US8454996B2/en not_active Expired - Fee Related
- 2011-11-22 US US13/302,720 patent/US8512747B2/en not_active Expired - Fee Related
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2013
- 2013-03-13 US US13/799,640 patent/US20130195976A1/en not_active Abandoned
- 2013-07-30 US US13/954,141 patent/US20140030336A1/en not_active Abandoned
- 2013-11-04 CY CY20131100974T patent/CY1114620T1/el unknown
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2014
- 2014-08-04 CY CY20141100588T patent/CY1115685T1/el unknown
- 2014-09-10 CY CY20141100730T patent/CY1115688T1/el unknown
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2015
- 2015-01-20 LU LU92636C patent/LU92636I2/xx unknown
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2017
- 2017-11-30 CY CY20171101261T patent/CY1119644T1/el unknown
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