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CY1112655T1 - Γλυκοζυλιωμενη ιl-7, παρασκευη και χρησεις - Google Patents

Γλυκοζυλιωμενη ιl-7, παρασκευη και χρησεις

Info

Publication number
CY1112655T1
CY1112655T1 CY20121100161T CY121100161T CY1112655T1 CY 1112655 T1 CY1112655 T1 CY 1112655T1 CY 20121100161 T CY20121100161 T CY 20121100161T CY 121100161 T CY121100161 T CY 121100161T CY 1112655 T1 CY1112655 T1 CY 1112655T1
Authority
CY
Cyprus
Prior art keywords
polypeptides
well
relates
preparation
cells
Prior art date
Application number
CY20121100161T
Other languages
Greek (el)
English (en)
Inventor
Michel Morre
Brigitte Assouline
Iann Rance
Anne Gregoire
Corinne Breque
Original Assignee
Cytheris
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cytheris filed Critical Cytheris
Publication of CY1112655T1 publication Critical patent/CY1112655T1/el

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/54Interleukins [IL]
    • C07K14/5418IL-7
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Transplantation (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CY20121100161T 2005-07-20 2012-02-16 Γλυκοζυλιωμενη ιl-7, παρασκευη και χρησεις CY1112655T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05291556A EP1746161A1 (fr) 2005-07-20 2005-07-20 IL-7 glycosylée, préparation et utilisations
EP06795556A EP1904635B1 (fr) 2005-07-20 2006-07-19 Il-7 glycosylee, preparation et utilisations

Publications (1)

Publication Number Publication Date
CY1112655T1 true CY1112655T1 (el) 2016-02-10

Family

ID=35385570

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20121100161T CY1112655T1 (el) 2005-07-20 2012-02-16 Γλυκοζυλιωμενη ιl-7, παρασκευη και χρησεις

Country Status (19)

Country Link
US (3) US7708985B2 (fr)
EP (2) EP1746161A1 (fr)
JP (2) JP5685363B2 (fr)
CN (2) CN105647939A (fr)
AT (1) ATE542901T1 (fr)
AU (1) AU2006271315B2 (fr)
CA (2) CA2615562C (fr)
CY (1) CY1112655T1 (fr)
DK (1) DK1904635T3 (fr)
EA (1) EA012802B1 (fr)
ES (1) ES2379732T3 (fr)
IL (1) IL188480A0 (fr)
NO (1) NO344802B1 (fr)
NZ (1) NZ564907A (fr)
PL (1) PL1904635T3 (fr)
PT (1) PT1904635E (fr)
SI (1) SI1904635T1 (fr)
WO (1) WO2007010401A2 (fr)
ZA (1) ZA200800533B (fr)

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EP1391513A1 (fr) 2002-08-08 2004-02-25 Cytheris Substance médicamenteuse IL-7, composition comprenant IL-7, procédé de sa préparation et ses utilisations
DK1699822T3 (da) 2003-12-30 2008-08-04 Merck Patent Gmbh IL-7-fusionsproteiner med antistofdele, fremstilling deraf og anvendelse deraf
EP2066336B1 (fr) 2006-09-28 2012-09-19 Merck Sharp & Dohme Corp. Utilisation d'il-10 pégilée pour traiter un cancer
CL2007003411A1 (es) * 2006-11-28 2008-07-04 Centelion Proteina fusion que consiste en una region fc de una inmunoglobulina con un fragmento o dominio soluble de un receptor para fgf; polinucleotido que la codifica y vector y celula que lo comprenden; composicion farmaceutica que comprende la proteina fu
CN101943688B (zh) * 2009-07-10 2013-01-02 复旦大学 一种利用质谱靶板富集糖基化肽段的方法
EP2808344A1 (fr) 2010-06-01 2014-12-03 Monash University Anticorps dirigés contre le récepteur tyrosine kinase c-Met
NZ707637A (en) * 2010-07-19 2016-09-30 Otago Innovation Ltd Signal biomarkers
AU2011325871B2 (en) 2010-11-05 2016-02-04 Medvet Science Pty Ltd Markers of endothelial progenitor cells and uses thereof
CA2820956C (fr) * 2010-12-10 2016-05-03 University Of Central Florida Research Foundation, Inc. Methodes et compositions comprenant des ligands du recepteur a l'il-7
EP2739301B1 (fr) 2011-08-03 2016-01-20 Cytheris Immunothérapie contre le vhc
RU2679889C2 (ru) 2013-04-18 2019-02-14 Армо Байосайенсиз, Инк. Способы применения интерлейкина-10 для лечения заболеваний и расстройств
US9823255B2 (en) 2013-06-17 2017-11-21 Armo Biosciences, Inc. Method for assessing protein identity and stability
CN105848674A (zh) 2013-11-11 2016-08-10 阿尔莫生物科技股份有限公司 将白细胞介素-10用于治疗疾病和病症的方法
CN104725484B (zh) * 2013-12-19 2018-03-13 中国科学院微生物研究所 一种糖基化多肽及其制备方法和其应用
EP3119412A1 (fr) 2014-03-21 2017-01-25 Boreal Invest Nanofiltration finale de compositions de protéines solubilisées en vue de l'élimination d'agrégats immunogènes
CN106573072A (zh) 2014-06-02 2017-04-19 阿尔莫生物科技股份有限公司 降低血清胆固醇的方法
MX2017004983A (es) 2014-10-22 2017-11-13 Armo Biosciences Inc Metodos para usar interleucina 10 para tratar enfermedades y trastornos.
CN104372021A (zh) * 2014-11-05 2015-02-25 太仓思源生物医药有限公司 人白细胞介素-2蛋白质的制备方法
WO2016126615A1 (fr) 2015-02-03 2016-08-11 Armo Biosciences, Inc. Procédés d'utilisation de l'interleukine-10 pour le traitement de maladies et de troubles
JP7121496B2 (ja) 2015-05-28 2022-08-18 アルモ・バイオサイエンシーズ・インコーポレイテッド 癌治療で使用するためのペグ化インターロイキン-10
CN114853873B (zh) 2015-06-11 2025-01-28 格纳西尼有限公司 经修饰的白细胞介素-7蛋白及其用途
AU2016341402B2 (en) 2015-10-23 2020-08-27 Apogenix Ag Single-chain GITR-receptor agonist proteins
KR102386735B1 (ko) 2015-11-06 2022-04-14 주식회사 제넥신 변형된 인터루킨-7 융합 단백질의 제형
WO2017095191A1 (fr) * 2015-12-04 2017-06-08 주식회사 제넥신 Composition pharmaceutique comprenant une protéine de fusion d'interleukine 7 fusionnés avec fc d'immunoglobuline pour la prévention ou le traitement de maladies causées par le papillomavirus humain
US11357827B2 (en) 2015-12-04 2022-06-14 Genexine, Inc. Method for preventing or treating influenza virus infection using pharmaceutical composition comprising immunoglobulin Fc-fused interleukin-7 fusion protein
CN107759697B (zh) * 2016-08-19 2023-03-24 安源医药科技(上海)有限公司 制备融合蛋白的方法
IL273202B2 (en) 2017-09-11 2024-08-01 Univ Monash Binding proteins to the human thrombin receptor, par4
WO2019144945A1 (fr) 2018-01-25 2019-08-01 I-Mab Anticorps anti-pd-l1 et fusions d'il-7
CA3119341A1 (fr) 2018-11-16 2020-05-22 Neoimmunetech, Inc. Methode de traitement d'une tumeur au moyen de l'association de la proteine il-7 et d'un inhibiteur de point de controle immunitaire
CN113614109A (zh) 2018-12-21 2021-11-05 Ose免疫疗法公司 双功能抗pd-1/il-7分子
AU2020334924A1 (en) * 2019-08-22 2022-04-07 The Regents Of The University Of California UBE3A for the treatment of Angelman syndrome
AU2020383176B2 (en) * 2019-11-15 2023-10-19 Genexine, Inc. Fusion protein including modified interleukin-7 and TGF beta receptor II and use thereof
JP2023512456A (ja) 2020-01-13 2023-03-27 ネオイミューンテック, インコーポレイテッド Il-7タンパク質と二重特異性抗体の組み合わせで腫瘍を治療する方法
JP2023512657A (ja) 2020-02-05 2023-03-28 ワシントン・ユニバーシティ Il-7タンパク質とcar保有免疫細胞の組み合わせで固形腫瘍を治療する方法
US20230398184A1 (en) 2020-10-26 2023-12-14 Neoimmunetech, Inc. Methods of inducing stem cell mobilization
WO2022094475A1 (fr) 2020-11-02 2022-05-05 Neoimmunetech, Inc. Utilisation de l'interleukine-7 pour le traitement du coronavirus
IL302482A (en) 2020-11-05 2023-06-01 Neoimmunetech Inc Method of treating a tumor with a combination of an il-7 protein and a nucleotide vaccine
WO2022117569A1 (fr) 2020-12-02 2022-06-09 Oncurious Nv Anticorps antagoniste de ccr8 en combinaison avec un anticorps agoniste du récepteur bêta de la lymphotoxine en thérapie contre le cancer
CN113817043B (zh) * 2021-09-22 2023-07-25 清华大学 制备活性铁调节激素的方法
JP2025501238A (ja) 2021-12-30 2025-01-17 ネオイミューンテック, インコーポレイテッド Il-7タンパク質とvegfアンタゴニストの併用による腫瘍の治療方法
WO2023133595A2 (fr) 2022-01-10 2023-07-13 Sana Biotechnology, Inc. Méthodes de dosage et d'administration ex vivo de particules lipidiques ou de vecteurs viraux ainsi que systèmes et utilisations associés
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KR20250089492A (ko) 2022-11-07 2025-06-18 네오이뮨텍, 인코퍼레이티드 비메틸화된 mgmt 프로모터를 갖는 종양의 치료 방법
WO2024150158A1 (fr) 2023-01-11 2024-07-18 Bright Peak Therapeutics Ag Polypeptides il-7, immunocytokines les comprenant et leurs utilisations
WO2024261027A1 (fr) 2023-06-19 2024-12-26 Vector Biopharma Ag Reciblage d'il-7 d'adénovirus pour une infection spécifique d'une cellule
CN117050178B (zh) * 2023-10-13 2024-01-12 北京百普赛斯生物科技股份有限公司 特异性检测il-7的抗体及应用
WO2025093541A1 (fr) 2023-10-31 2025-05-08 Ose Immunotherapeutics Combinaison d'interleukine 7 et de vaccin antigénique associé à une tumeur

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US5714585A (en) * 1987-10-26 1998-02-03 Sterling Winthrop, Inc. Antibodies that are immunoreactive with interleukin-7
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EP1391513A1 (fr) 2002-08-08 2004-02-25 Cytheris Substance médicamenteuse IL-7, composition comprenant IL-7, procédé de sa préparation et ses utilisations

Also Published As

Publication number Publication date
ZA200800533B (en) 2008-12-31
AU2006271315B2 (en) 2011-08-11
US20100196312A1 (en) 2010-08-05
AU2006271315A1 (en) 2007-01-25
CA2859145A1 (fr) 2007-01-25
WO2007010401A3 (fr) 2007-04-19
ES2379732T3 (es) 2012-05-03
IL188480A0 (en) 2008-04-13
EP1904635A2 (fr) 2008-04-02
US20080206190A1 (en) 2008-08-28
BRPI0613747A2 (pt) 2011-02-08
CA2615562A1 (fr) 2007-01-25
PL1904635T3 (pl) 2012-07-31
EA012802B1 (ru) 2009-12-30
CN105647939A (zh) 2016-06-08
CA2615562C (fr) 2014-11-04
JP2009501543A (ja) 2009-01-22
WO2007010401A2 (fr) 2007-01-25
SI1904635T1 (sl) 2012-10-30
PT1904635E (pt) 2012-03-06
ATE542901T1 (de) 2012-02-15
CN101228275A (zh) 2008-07-23
EP1904635B1 (fr) 2012-01-25
US20120016104A1 (en) 2012-01-19
US8153114B2 (en) 2012-04-10
DK1904635T3 (da) 2012-02-27
US7708985B2 (en) 2010-05-04
HK1115154A1 (en) 2008-11-21
EP1746161A1 (fr) 2007-01-24
EA200800368A1 (ru) 2008-06-30
JP5685363B2 (ja) 2015-03-18
JP2015057392A (ja) 2015-03-26
NZ564907A (en) 2011-09-30
NO20080045L (no) 2008-04-21
CN101228275B (zh) 2016-02-24
US8034327B2 (en) 2011-10-11
CA2859145C (fr) 2018-11-27
NO344802B1 (no) 2020-05-04

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