CY1111970T1 - Μεθοδοι για την ανιχνευση της νοσου αλτσχαϊμερ - Google Patents
Μεθοδοι για την ανιχνευση της νοσου αλτσχαϊμερInfo
- Publication number
- CY1111970T1 CY1111970T1 CY20111101024T CY111101024T CY1111970T1 CY 1111970 T1 CY1111970 T1 CY 1111970T1 CY 20111101024 T CY20111101024 T CY 20111101024T CY 111101024 T CY111101024 T CY 111101024T CY 1111970 T1 CY1111970 T1 CY 1111970T1
- Authority
- CY
- Cyprus
- Prior art keywords
- disease
- methods
- altscheimer
- detection
- alzheimer
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 238000001514 detection method Methods 0.000 title 1
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 208000024827 Alzheimer disease Diseases 0.000 abstract 3
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 108700028369 Alleles Proteins 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 238000004393 prognosis Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Neurosurgery (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Neurology (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Biotechnology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Animal Behavior & Ethology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Μέθοδοι για τη διάγνωση ή την πρόγνωση της νόσου Αλτσχάϊμερ σε ένα άτομο. Η εν λόγω μέθοδος περιλαμβάνει τουλάχιστον ένα στάδιο ανίχνευσης της παρουσίας ή της απουσίας του πολυμορφισμού rs908832 του γονιδίου ABACA2. Η παρουσία του ελάσσονος αλληλίου του πολυμορφισμού rs908832 του γονιδίου ABACA2 υποδεικνύει ότι το υποκείμενο μπορεί να έχει προσβληθεί από τη νόσο Αλτσχάϊμερ ή ακόμη να παρουσιάζει ένα αυξημένο κίνδυνο να αναπτύξει τη νόσο Αλτσχάϊμερ.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0307501A FR2856409B1 (fr) | 2003-06-20 | 2003-06-20 | Methodes de detection de la maladie d'alzheimer |
| EP04767370A EP1639139B1 (fr) | 2003-06-20 | 2004-06-17 | Methodes de detection de la maladie d'alzheimer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1111970T1 true CY1111970T1 (el) | 2015-11-04 |
Family
ID=33484616
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20111101024T CY1111970T1 (el) | 2003-06-20 | 2011-10-27 | Μεθοδοι για την ανιχνευση της νοσου αλτσχαϊμερ |
Country Status (24)
| Country | Link |
|---|---|
| EP (1) | EP1639139B1 (el) |
| JP (1) | JP4691491B2 (el) |
| KR (1) | KR101170651B1 (el) |
| CN (1) | CN1809645B (el) |
| AR (1) | AR044492A1 (el) |
| AT (1) | ATE518005T1 (el) |
| AU (1) | AU2004249919B2 (el) |
| BR (1) | BRPI0411658A (el) |
| CA (1) | CA2529633C (el) |
| CY (1) | CY1111970T1 (el) |
| DK (1) | DK1639139T3 (el) |
| ES (1) | ES2370491T3 (el) |
| FR (1) | FR2856409B1 (el) |
| HR (1) | HRP20110778T1 (el) |
| IL (1) | IL172690A0 (el) |
| MX (1) | MXPA05012800A (el) |
| NO (1) | NO20060257L (el) |
| PL (1) | PL1639139T3 (el) |
| PT (1) | PT1639139E (el) |
| RU (2) | RU2483108C2 (el) |
| SI (1) | SI1639139T1 (el) |
| TW (1) | TWI352738B (el) |
| WO (1) | WO2004113568A2 (el) |
| ZA (1) | ZA200509945B (el) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2315559C1 (ru) * | 2006-10-13 | 2008-01-27 | Иван Васильевич Максимович | Способ комплексной лучевой диагностики доклинических и клинических стадий болезни альцгеймера |
| CN103013989A (zh) * | 2011-09-23 | 2013-04-03 | 深圳北京大学香港科技大学医学中心 | 与老年痴呆症发病相关的细胞周期依赖性激酶5的单核苷酸多态性位点 |
| GB201212084D0 (en) * | 2012-07-06 | 2012-08-22 | Randox Lab Ltd | Tropomyosin isoforms related to alzheimers disease and mild cognitive impairment |
| CN102768189B (zh) * | 2012-07-30 | 2014-11-19 | 黄石 | 一种药物筛选方法 |
| CN104313144B (zh) * | 2014-10-16 | 2017-02-01 | 卫生部北京医院 | 一种检测阿尔茨海默病易感性的试剂 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5853995A (en) * | 1997-01-07 | 1998-12-29 | Research Development Foundation | Large scale genotyping of diseases and a diagnostic test for spinocerebellar ataxia type 6 |
| WO2001014414A2 (en) * | 1999-08-20 | 2001-03-01 | Activepass Pharmaceuticals, Inc. | Human abc2 transporter and uses thereof |
| EP1304922A2 (en) * | 2000-07-20 | 2003-05-02 | Cephalon, Inc. | Gene-targeted non-human mammal with human fad presenilin mutation and generational offspring |
| JP2004147502A (ja) * | 2000-07-26 | 2004-05-27 | Banyu Pharmaceut Co Ltd | ヒト及びラットabca2遺伝子 |
| US20020169137A1 (en) * | 2001-02-09 | 2002-11-14 | Active Pass Pharmaceuticals, Inc. | Regulation of amyloid precursor protein expression by modification of ABC transporter expression or activity |
| WO2002101392A2 (en) * | 2001-06-08 | 2002-12-19 | Xenon Genetics, Inc. | Methods for treating disorders of the nervous and reproductive systems |
-
2003
- 2003-06-20 FR FR0307501A patent/FR2856409B1/fr not_active Expired - Fee Related
-
2004
- 2004-06-09 AR ARP040101994A patent/AR044492A1/es active IP Right Grant
- 2004-06-17 CN CN2004800172750A patent/CN1809645B/zh not_active Expired - Fee Related
- 2004-06-17 AU AU2004249919A patent/AU2004249919B2/en not_active Ceased
- 2004-06-17 SI SI200431759T patent/SI1639139T1/sl unknown
- 2004-06-17 ES ES04767370T patent/ES2370491T3/es not_active Expired - Lifetime
- 2004-06-17 HR HR20110778T patent/HRP20110778T1/hr unknown
- 2004-06-17 AT AT04767370T patent/ATE518005T1/de active
- 2004-06-17 JP JP2006516300A patent/JP4691491B2/ja not_active Expired - Fee Related
- 2004-06-17 PL PL04767370T patent/PL1639139T3/pl unknown
- 2004-06-17 MX MXPA05012800A patent/MXPA05012800A/es active IP Right Grant
- 2004-06-17 KR KR1020057024490A patent/KR101170651B1/ko not_active Expired - Fee Related
- 2004-06-17 EP EP04767370A patent/EP1639139B1/fr not_active Expired - Lifetime
- 2004-06-17 WO PCT/FR2004/001509 patent/WO2004113568A2/fr not_active Ceased
- 2004-06-17 RU RU2009104533/10A patent/RU2483108C2/ru not_active IP Right Cessation
- 2004-06-17 CA CA2529633A patent/CA2529633C/fr not_active Expired - Fee Related
- 2004-06-17 BR BRPI0411658-5A patent/BRPI0411658A/pt not_active IP Right Cessation
- 2004-06-17 PT PT04767370T patent/PT1639139E/pt unknown
- 2004-06-17 DK DK04767370.2T patent/DK1639139T3/da active
- 2004-06-17 RU RU2006101561/13A patent/RU2380423C2/ru not_active IP Right Cessation
- 2004-06-18 TW TW093117572A patent/TWI352738B/zh not_active IP Right Cessation
-
2005
- 2005-12-07 ZA ZA200509945A patent/ZA200509945B/en unknown
- 2005-12-19 IL IL172690A patent/IL172690A0/en not_active IP Right Cessation
-
2006
- 2006-01-18 NO NO20060257A patent/NO20060257L/no not_active Application Discontinuation
-
2011
- 2011-10-27 CY CY20111101024T patent/CY1111970T1/el unknown
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