[go: up one dir, main page]

ATE536420T1 - Verbesserte verfahren für beaming - Google Patents

Verbesserte verfahren für beaming

Info

Publication number
ATE536420T1
ATE536420T1 AT06817236T AT06817236T ATE536420T1 AT E536420 T1 ATE536420 T1 AT E536420T1 AT 06817236 T AT06817236 T AT 06817236T AT 06817236 T AT06817236 T AT 06817236T AT E536420 T1 ATE536420 T1 AT E536420T1
Authority
AT
Austria
Prior art keywords
beaming
improved methods
permitted
increase
rare
Prior art date
Application number
AT06817236T
Other languages
English (en)
Inventor
Bert Vogelstein
Frank Diehl
Kenneth Kinzler
Ming Li
Original Assignee
Univ Johns Hopkins
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Johns Hopkins filed Critical Univ Johns Hopkins
Application granted granted Critical
Publication of ATE536420T1 publication Critical patent/ATE536420T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/6858Allele-specific amplification
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01RMEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R31/00Arrangements for testing electric properties; Arrangements for locating electric faults; Arrangements for electrical testing characterised by what is being tested not provided for elsewhere
    • G01R31/327Testing of circuit interrupters, switches or circuit-breakers
    • G01R31/3277Testing of circuit interrupters, switches or circuit-breakers of low voltage devices, e.g. domestic or industrial devices, such as motor protections, relays, rotation switches
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01RMEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R31/00Arrangements for testing electric properties; Arrangements for locating electric faults; Arrangements for electrical testing characterised by what is being tested not provided for elsewhere
    • G01R31/50Testing of electric apparatus, lines, cables or components for short-circuits, continuity, leakage current or incorrect line connections
    • G01R31/52Testing for short-circuits, leakage current or ground faults
    • HELECTRICITY
    • H02GENERATION; CONVERSION OR DISTRIBUTION OF ELECTRIC POWER
    • H02HEMERGENCY PROTECTIVE CIRCUIT ARRANGEMENTS
    • H02H1/00Details of emergency protective circuit arrangements
    • H02H1/0007Details of emergency protective circuit arrangements concerning the detecting means
    • H02H1/0015Using arc detectors
    • HELECTRICITY
    • H02GENERATION; CONVERSION OR DISTRIBUTION OF ELECTRIC POWER
    • H02HEMERGENCY PROTECTIVE CIRCUIT ARRANGEMENTS
    • H02H3/00Emergency protective circuit arrangements for automatic disconnection directly responsive to an undesired change from normal electric working condition with or without subsequent reconnection ; integrated protection
    • H02H3/26Emergency protective circuit arrangements for automatic disconnection directly responsive to an undesired change from normal electric working condition with or without subsequent reconnection ; integrated protection responsive to difference between voltages or between currents; responsive to phase angle between voltages or between currents
    • H02H3/32Emergency protective circuit arrangements for automatic disconnection directly responsive to an undesired change from normal electric working condition with or without subsequent reconnection ; integrated protection responsive to difference between voltages or between currents; responsive to phase angle between voltages or between currents involving comparison of the voltage or current values at corresponding points in different conductors of a single system, e.g. of currents in go and return conductors
    • H02H3/33Emergency protective circuit arrangements for automatic disconnection directly responsive to an undesired change from normal electric working condition with or without subsequent reconnection ; integrated protection responsive to difference between voltages or between currents; responsive to phase angle between voltages or between currents involving comparison of the voltage or current values at corresponding points in different conductors of a single system, e.g. of currents in go and return conductors using summation current transformers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Power Engineering (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nanotechnology (AREA)
AT06817236T 2005-10-24 2006-10-20 Verbesserte verfahren für beaming ATE536420T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US72923505P 2005-10-24 2005-10-24
PCT/US2006/041115 WO2007050465A2 (en) 2005-10-24 2006-10-20 Improved methods for beaming

Publications (1)

Publication Number Publication Date
ATE536420T1 true ATE536420T1 (de) 2011-12-15

Family

ID=37968413

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06817236T ATE536420T1 (de) 2005-10-24 2006-10-20 Verbesserte verfahren für beaming

Country Status (10)

Country Link
US (4) US9360526B2 (de)
EP (2) EP1948816B1 (de)
AT (1) ATE536420T1 (de)
CY (1) CY1112525T1 (de)
DK (1) DK1948816T3 (de)
ES (2) ES2381204T3 (de)
PL (1) PL1948816T3 (de)
PT (1) PT1948816E (de)
SI (1) SI1948816T1 (de)
WO (1) WO2007050465A2 (de)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7968287B2 (en) 2004-10-08 2011-06-28 Medical Research Council Harvard University In vitro evolution in microfluidic systems
DE602005009324D1 (de) 2005-04-06 2008-10-09 Maurice Stroun Methode zur Krebsdiagnose mittels Nachweis von DNA und RNA im Kreislauf
PT1948816E (pt) * 2005-10-24 2012-03-19 Univ Johns Hopkins Processos melhorados de focalização
EP1984738A2 (de) 2006-01-11 2008-10-29 Raindance Technologies, Inc. Mikrofluidische vorrichtungen und verfahren zur verwendung bei der bildung und kontrolle von nanoreaktoren
US9562837B2 (en) 2006-05-11 2017-02-07 Raindance Technologies, Inc. Systems for handling microfludic droplets
WO2007133710A2 (en) * 2006-05-11 2007-11-22 Raindance Technologies, Inc. Microfluidic devices and methods of use thereof
US8772046B2 (en) 2007-02-06 2014-07-08 Brandeis University Manipulation of fluids and reactions in microfluidic systems
WO2008130623A1 (en) 2007-04-19 2008-10-30 Brandeis University Manipulation of fluids, fluid components and reactions in microfluidic systems
GB2453173A (en) 2007-09-28 2009-04-01 Dxs Ltd Polynucleotide primers
US12038438B2 (en) 2008-07-18 2024-07-16 Bio-Rad Laboratories, Inc. Enzyme quantification
WO2010009365A1 (en) 2008-07-18 2010-01-21 Raindance Technologies, Inc. Droplet libraries
US20100041048A1 (en) * 2008-07-31 2010-02-18 The Johns Hopkins University Circulating Mutant DNA to Assess Tumor Dynamics
US8583380B2 (en) 2008-09-05 2013-11-12 Aueon, Inc. Methods for stratifying and annotating cancer drug treatment options
US8528589B2 (en) 2009-03-23 2013-09-10 Raindance Technologies, Inc. Manipulation of microfluidic droplets
EP4484577A3 (de) 2010-02-12 2025-03-26 Bio-Rad Laboratories, Inc. Digitale analytanalyse
US9399797B2 (en) 2010-02-12 2016-07-26 Raindance Technologies, Inc. Digital analyte analysis
WO2012040387A1 (en) 2010-09-24 2012-03-29 The Board Of Trustees Of The Leland Stanford Junior University Direct capture, amplification and sequencing of target dna using immobilized primers
WO2012109600A2 (en) 2011-02-11 2012-08-16 Raindance Technologies, Inc. Methods for forming mixed droplets
US9150852B2 (en) 2011-02-18 2015-10-06 Raindance Technologies, Inc. Compositions and methods for molecular labeling
EP3709018A1 (de) 2011-06-02 2020-09-16 Bio-Rad Laboratories, Inc. Mikrofluidische vorrichtung zum nachweis von komponenten einer chemischen reaktion
US8658430B2 (en) 2011-07-20 2014-02-25 Raindance Technologies, Inc. Manipulating droplet size
WO2013083810A1 (en) * 2011-12-09 2013-06-13 F. Hoffmann-La Roche Ag Identification of non-responders to her2 inhibitors
US20130309667A1 (en) * 2012-05-15 2013-11-21 Anthony P. Shuber Primers for analyzing methylated sequences and methods of use thereof
US10119134B2 (en) 2013-03-15 2018-11-06 Abvitro Llc Single cell bar-coding for antibody discovery
DE102013211113A1 (de) * 2013-06-14 2014-12-18 Siemens Aktiengesellschaft Verfahren zur kombinierten Quantifizierung und Sequenzierung von mindestens einer Ziel-Nukleinsäure
US11901041B2 (en) 2013-10-04 2024-02-13 Bio-Rad Laboratories, Inc. Digital analysis of nucleic acid modification
US9944977B2 (en) 2013-12-12 2018-04-17 Raindance Technologies, Inc. Distinguishing rare variations in a nucleic acid sequence from a sample
MX378730B (es) 2014-09-15 2025-03-11 Abvitro Llc Secuenciacion de bibliotecas de nucleotidos de alto rendimiento
CN107427823B (zh) * 2015-03-24 2020-07-14 日立金属株式会社 陶瓷蜂窝结构体
US11085073B2 (en) 2015-04-24 2021-08-10 Qiagen Gmbh Method for immobilizing a nucleic acid molecule on a solid support
WO2016170179A1 (en) * 2015-04-24 2016-10-27 Qiagen Gmbh Method for immobilizing a nucleic acid molecule on solid support
US9938572B1 (en) 2015-09-08 2018-04-10 Raindance Technologies, Inc. System and method for forming an emulsion
CN106929598B (zh) * 2017-05-04 2019-07-05 湖南融健基因生物科技有限公司 一种乳液中进行滚环扩增的数字核酸分析方法
EP3700543A4 (de) * 2017-10-24 2021-08-25 Elani, Dalia Verfahren zur behandlung einer ischämischen erkrankung
EP3853373A4 (de) * 2018-09-17 2022-06-22 The University of North Carolina at Chapel Hill Verfahren zur quantifizierung von dns-fragmenten in einer probe nach grösse
US11474109B2 (en) 2018-11-16 2022-10-18 Scintimetrics, Inc. Compositions and methods for controllably merging emulsion droplets and sample analysis
EP3725894A1 (de) 2019-04-16 2020-10-21 Blod Diagnostik GmbH Vorrichtung und verfahren zur nukleinsäurezielanreicherung, -suspension und -quantifizierung
EP4058763A4 (de) 2019-11-15 2023-11-29 Scintimetrics, Inc. Zusammensetzungen und verfahren basierend auf der diffusion von fluorophoren

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5888778A (en) * 1997-06-16 1999-03-30 Exact Laboratories, Inc. High-throughput screening method for identification of genetic mutations or disease-causing microorganisms using segmented primers
GB9900298D0 (en) * 1999-01-07 1999-02-24 Medical Res Council Optical sorting method
US6355431B1 (en) * 1999-04-20 2002-03-12 Illumina, Inc. Detection of nucleic acid amplification reactions using bead arrays
DE10048797A1 (de) * 2000-10-02 2002-04-18 Bayer Ag Wirkstoffhaltige Emulsionen
AUPS298102A0 (en) * 2002-06-13 2002-07-04 Nucleics Pty Ltd Method for performing chemical reactions
EP1594950A4 (de) * 2003-01-29 2007-07-25 454 Corp Verfahren zur herstellung von einzelstrang-dna-bibliotheken
CA2531105C (en) * 2003-07-05 2015-03-17 The Johns Hopkins University Method and compositions for detection and enumeration of genetic variations
WO2005073410A2 (en) * 2004-01-28 2005-08-11 454 Corporation Nucleic acid amplification with continuous flow emulsion
NZ551996A (en) * 2004-05-13 2010-07-30 Anita Goel Nano-PCR: Methods and devices for nucleic acid amplification and detection
US20060228721A1 (en) * 2005-04-12 2006-10-12 Leamon John H Methods for determining sequence variants using ultra-deep sequencing
PT1948816E (pt) 2005-10-24 2012-03-19 Univ Johns Hopkins Processos melhorados de focalização
US20080242560A1 (en) * 2006-11-21 2008-10-02 Gunderson Kevin L Methods for generating amplified nucleic acid arrays

Also Published As

Publication number Publication date
EP1948816B1 (de) 2011-12-07
US10150991B2 (en) 2018-12-11
WO2007050465A2 (en) 2007-05-03
EP2428579A1 (de) 2012-03-14
US20110059435A1 (en) 2011-03-10
ES2381204T3 (es) 2012-05-24
EP2428579B1 (de) 2013-05-29
SI1948816T1 (sl) 2012-04-30
US20200123600A1 (en) 2020-04-23
ES2426031T3 (es) 2013-10-18
HK1121193A1 (en) 2009-04-17
PT1948816E (pt) 2012-03-19
US9360526B2 (en) 2016-06-07
PL1948816T3 (pl) 2012-07-31
US10837050B2 (en) 2020-11-17
US20160376645A1 (en) 2016-12-29
CY1112525T1 (el) 2015-12-09
US20120014879A1 (en) 2012-01-19
EP1948816A4 (de) 2009-11-04
US20130040300A9 (en) 2013-02-14
WO2007050465A3 (en) 2007-10-25
EP1948816A2 (de) 2008-07-30
DK1948816T3 (da) 2012-04-02

Similar Documents

Publication Publication Date Title
ATE536420T1 (de) Verbesserte verfahren für beaming
ATE496142T1 (de) Verfahren zur diagnose von nicht-kleinzelligem lungenkrebs
MX2007012782A (es) Metodos y acidos nucleicos para analisis de trastornos proliferativos celulares.
IL181132A0 (en) Use of transthyretin as a biomarker for colorectal adenoma and/or carcinoma; method for detection and test system
TW200713187A (en) Display, column driver integrated circuit, and multi-level detector, and multi-level detection method
ATE534748T1 (de) Direkter snp-nachweis mit nichtamplifizierter dna
DE60333295D1 (de) Verfahren zum nachweis abnormal methylierter nukleinsäure in heterogenen biologischen proben
DK2258871T3 (da) Fremgangsmåder og nukleinsyrer til analyse af celleproliferative lidelser
DE60315715D1 (de) Verwendung von nicotinamide n-methyltransferase zur diagnose von kolorektalem krebs
WO2005001141A3 (en) Methods and nucleic acids for analyses of colorectal cell proliferative disorders
WO2007149065A3 (en) Methods and apparatuses for detecting chemical or biological agents
DE60325382D1 (de) Verfahren zur diagnose von gebärmutterhalskrebs
WO2006007403A3 (en) Methods for identifying and measuring s-nitrosothiol bonds in heme-containing cells and molecules
CY1111970T1 (el) Μεθοδοι για την ανιχνευση της νοσου αλτσχαϊμερ
ATE494390T1 (de) Verfahren und nukleinsäuren zur analyse von störungen der proliferation von kolonzellen
WO2005100611A3 (en) Detection of viral nucleic acid and method for reverse transcribing rna
ATE504833T1 (de) Verfahren zur bestimmung des phänotyps von zellen
WO2006110587A3 (en) Ddr2 in cancer diagnosis, detection and treatment
IL189185A0 (en) Use of an endoplasmin fragment and derivatives thereof as a biomarker for colorectal adenoma and/or carcinoma; method for detection and test system
WO2005074522A3 (en) Detection of ruminant dna via pcr
WO2006110583A3 (en) Adam10 in cancer diagnosis, detection and treatment
CY1115206T1 (el) Διαγνωστικη δοκιμη για ευαισθησια σε αναστολεις της b-raf κινασης
TW200514984A (en) Nucleic acid molecule for detecting SARS virus and method and detection kit using the same for detecting SARS virus
GB0617120D0 (en) Method of prognosis