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CO5560609A2 - Oxazolidinona y/o isoxazolina como agentes antibacteriales - Google Patents

Oxazolidinona y/o isoxazolina como agentes antibacteriales

Info

Publication number
CO5560609A2
CO5560609A2 CO04021466A CO04021466A CO5560609A2 CO 5560609 A2 CO5560609 A2 CO 5560609A2 CO 04021466 A CO04021466 A CO 04021466A CO 04021466 A CO04021466 A CO 04021466A CO 5560609 A2 CO5560609 A2 CO 5560609A2
Authority
CO
Colombia
Prior art keywords
independently selected
groups
isoxazoline
oxazolidinone
antibacterial agents
Prior art date
Application number
CO04021466A
Other languages
English (en)
Inventor
Michael Barry Gravestock
Neil James Hales
Michael Lingard Swain
Sheila Irene Hauck
Stuart Dennett Mills
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0121942A external-priority patent/GB0121942D0/en
Priority claimed from GB0215420A external-priority patent/GB0215420D0/en
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of CO5560609A2 publication Critical patent/CO5560609A2/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

1.- Un compuesto de la fórmula (I), o una sal farmacéuticamente aceptable, o un éster hidrolizable in-vivo de este, En donde (I) C es una mitad biaril C'-C"Donde C´ y C" son independientemente anillos de arilo o heteroarilo de forma que el fragmento central C está representado por cualquiera de los grupos D a L siguientes:donde los grupos D a L pueden estar pegados a los anillos A y B en cualquier orientación; En donde A y B son seleccionados independientemente de donde i) y/o ii están enlazados como se muestra en (I) mediante la posición 3 al grupo C y sustituido en la posición 5 como se muestra en (I) por -CH2-R1a y -CH2-R1b;R2a, R2b, R3a y R3b son independientemente hidrógeno o flúor;R1a y R1b son independientemente seleccionados de hidroxi, -Osi(tri-alquilo(1-6C) (donde los 3 grupos alquilo(1-6C) son independientemente seleccionados de todos los posibles grupos alquilo(1-6C), -NHC(=W)R4, -OC(=O)R4, donde W es O o S; ...
CO04021466A 2001-09-11 2004-03-09 Oxazolidinona y/o isoxazolina como agentes antibacteriales CO5560609A2 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0121942A GB0121942D0 (en) 2001-09-11 2001-09-11 Chemical compounds
GB0215420A GB0215420D0 (en) 2002-07-04 2002-07-04 Chemical compounds

Publications (1)

Publication Number Publication Date
CO5560609A2 true CO5560609A2 (es) 2005-09-30

Family

ID=26246531

Family Applications (1)

Application Number Title Priority Date Filing Date
CO04021466A CO5560609A2 (es) 2001-09-11 2004-03-09 Oxazolidinona y/o isoxazolina como agentes antibacteriales

Country Status (25)

Country Link
US (2) US7396847B2 (es)
EP (1) EP1427711B1 (es)
JP (1) JP2005507386A (es)
KR (1) KR20040044886A (es)
CN (1) CN1639136A (es)
AR (1) AR036778A1 (es)
AT (1) ATE299502T1 (es)
AU (1) AU2002329393B2 (es)
BR (1) BR0212458A (es)
CA (1) CA2459766A1 (es)
CO (1) CO5560609A2 (es)
DE (1) DE60205030T2 (es)
DK (1) DK1427711T3 (es)
ES (1) ES2244802T3 (es)
HU (1) HUP0401005A3 (es)
IL (1) IL160739A0 (es)
IS (1) IS7175A (es)
MX (1) MXPA04002303A (es)
NO (1) NO327010B1 (es)
NZ (1) NZ531621A (es)
PL (1) PL369183A1 (es)
PT (1) PT1427711E (es)
RU (1) RU2004111285A (es)
SI (1) SI1427711T1 (es)
WO (1) WO2003022824A1 (es)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6667299B1 (en) * 2000-03-16 2003-12-23 Hollis-Eden Pharmaceuticals, Inc. Pharmaceutical compositions and treatment methods
JP2005512975A (ja) 2001-10-25 2005-05-12 アストラゼネカ アクチボラグ 抗菌薬として有用なイソキサゾリン誘導体
KR20040086465A (ko) 2002-02-28 2004-10-08 아스트라제네카 아베 화합물
AU2003207340A1 (en) * 2002-02-28 2003-09-09 Astrazeneca Ab 3-cyclyl-5-(nitrogen-containing 5-membered ring) methyl-oxazolidinone derivatives and their use as antibacterial agents
AU2003227654A1 (en) * 2002-04-25 2003-11-10 Basf Aktiengesellschaft 3-heteroaryl substituted 5-methyloxymethyl isoxazolines used as herbicides
TW200420573A (en) 2002-09-26 2004-10-16 Rib X Pharmaceuticals Inc Bifunctional heterocyclic compounds and methods of making and using same
BR0316688A (pt) * 2002-11-28 2005-10-18 Astrazeneca Ab Composto, prodroga de um composto, método de produzir um efeito antibacteriano em um animal de sangue quente, uso de um composto, composição farmacêutica, e, processo para a preparação de um composto
GB0227701D0 (en) * 2002-11-28 2003-01-08 Astrazeneca Ab Chemical compounds
US7498350B2 (en) 2002-11-28 2009-03-03 Astrazeneca Ab Oxazolidinones as antibacterial agents
GB0229521D0 (en) * 2002-12-19 2003-01-22 Astrazeneca Ab Chemical compounds
GB0229526D0 (en) * 2002-12-19 2003-01-22 Astrazeneca Ab Chemical compounds
GB0229522D0 (en) * 2002-12-19 2003-01-22 Astrazeneca Ab Chemical compounds
TW200500360A (en) 2003-03-01 2005-01-01 Astrazeneca Ab Hydroxymethyl compounds
GB0304723D0 (en) * 2003-03-01 2003-04-02 Astrazeneca Ab Chemical compounds
US8324398B2 (en) 2003-06-03 2012-12-04 Rib-X Pharmaceuticals, Inc. Process for the synthesis of biaryl oxazolidinones
EP2492264A3 (en) 2003-06-03 2012-12-19 Rib-X Pharmaceuticals, Inc. Biaryl Heterocyclic Compounds And Methods Of Making And Using The Same
WO2005012271A2 (en) * 2003-07-29 2005-02-10 Rib-X Pharmaceuticals, Inc. Process for the synthesis of biaryl oxazolidinones
ES2536001T3 (es) * 2003-07-29 2015-05-19 Melinta Therapeutics, Inc. Procedimiento para la síntesis de biariloxazolidinonas
AR046782A1 (es) 2003-12-17 2005-12-21 Rib X Pharmaceuticals Inc Compuestos heterociclicos de biarilo halogenados, composiciones farmaceuticas que los contienen, metodos para su elaboracion y su uso como medicamentos.
KR100854211B1 (ko) 2003-12-18 2008-08-26 동아제약주식회사 신규한 옥사졸리디논 유도체, 그의 제조방법 및 이를유효성분으로 하는 항생제용 약학 조성물
US8202843B2 (en) 2004-02-27 2012-06-19 Rib-X Pharmaceuticals, Inc. Macrocyclic compounds and methods of making and using the same
US20080064689A1 (en) * 2004-05-25 2008-03-13 Astrazeneca Ab 3-[4-(6-Pyridin-3-Yl)-3-Phenyl] -5-(1H-1,2,3-Triazol-1-Ylmethyl)-1,3-Oxazolidin-2-Ones as Antibacterial Agents
MXPA06013540A (es) * 2004-05-25 2007-01-26 Astrazeneca Ab Derivados de 3-(4-(2 -dihidroisoxasol -3-ilpiridin-5-il) fenil)-5- triazol-1- ilmetiloxazolidin -2-ona como inhibidores de mao para el tratamiento de infecciones bacterianas.
GB0411596D0 (en) * 2004-05-25 2004-06-30 Astrazeneca Ab Chemical process
DOP2005000123A (es) 2004-07-02 2011-07-15 Merck Sharp & Dohme Inhibidores de cetp
EP1799677A1 (en) * 2004-10-08 2007-06-27 Ranbaxy Laboratories Limited Oxazolidinone derivatives as antimicrobials
EP1874782A1 (en) 2005-04-15 2008-01-09 Ranbaxy Laboratories Limited Oxazolidinone derivatives as antimicrobials
ATE496914T1 (de) 2005-06-08 2011-02-15 Rib X Pharmaceuticals Inc Verfahren zur synthese von triazolen
WO2007025098A2 (en) 2005-08-24 2007-03-01 Rib-X Pharmaceuticals, Inc. Triazole compounds and methods of making and using the same
WO2007025089A2 (en) 2005-08-24 2007-03-01 Rib-X Pharmaceutical, Inc. Triazole compounds and methods of making and using the same
MX2011003820A (es) 2008-10-10 2011-06-16 Trius Therapeutics Metodos para preparar oxazolidinonas y composiciones que las contienen.
CN107082790A (zh) 2009-02-03 2017-08-22 默沙东公司 一种噁唑烷酮化合物的晶型
US8580767B2 (en) * 2009-05-28 2013-11-12 Trius Therapeutics, Inc. Oxazolidinone containing dimer compounds, compositions and methods to make and use
KR101561964B1 (ko) 2013-11-15 2015-10-20 한국과학기술연구원 옥사졸리디논 화합물 및 이를 포함하는 c형 간염 예방 또는 치료용 약학 조성물
CN114874131B (zh) * 2015-02-27 2025-03-25 海洋规划生物工厂株式会社 Kakeromycin及其衍生物的制造方法
CN106083994B (zh) * 2016-04-18 2019-12-06 南京曼杰生物科技有限公司 取代的噁唑烷酮水溶性衍生物及其应用
US20170333305A1 (en) * 2016-05-23 2017-11-23 Microban Products Company Topical skin product having retention property
EP3723758A4 (en) 2017-12-13 2021-06-23 Merck Sharp & Dohme Corp. PHARMACEUTICAL COMPOSITIONS OF TEDICOLIDE PHOSPHATE
CN113149924B (zh) * 2021-03-29 2023-11-03 苏州大学 一种异噁唑啉的简单制备方法
CN113831517A (zh) * 2021-09-09 2021-12-24 万凯新材料股份有限公司 抗菌及抗紫外聚酯的制备方法

Family Cites Families (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5043443A (en) * 1988-07-29 1991-08-27 Du Pont Merck Pharmaceutical Company Aminomethyloxooxazolidinyl arylbenzene derivatives
US4948801A (en) * 1988-07-29 1990-08-14 E. I. Du Pont De Nemours And Company Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents
SK283420B6 (sk) 1992-05-08 2003-07-01 Pharmacia & Upjohn Company Antimikrobiálne oxazolidinóny obsahujúce substituované diazínové skupiny
GB9521508D0 (en) 1995-10-20 1995-12-20 Zeneca Ltd Chemical compounds
GB9601666D0 (en) 1996-01-27 1996-03-27 Zeneca Ltd Chemical compounds
GB9702213D0 (en) 1996-02-24 1997-03-26 Zeneca Ltd Chemical compounds
GB9604301D0 (en) 1996-02-29 1996-05-01 Zeneca Ltd Chemical compounds
GB9609919D0 (en) 1996-05-11 1996-07-17 Zeneca Ltd Chemical compounds
GB9614236D0 (en) 1996-07-06 1996-09-04 Zeneca Ltd Chemical compounds
GB9614238D0 (en) 1996-07-06 1996-09-04 Zeneca Ltd Chemical compounds
GB9717807D0 (en) 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
GB9717804D0 (en) 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
AU8872198A (en) 1997-08-29 1999-03-22 Zeneca Limited Aminometyl oxooxazolidinyl benzene derivatives
GB9725244D0 (en) 1997-11-29 1998-01-28 Zeneca Ltd Chemical compounds
AU1694099A (en) 1997-12-26 1999-07-19 Cheil Jedang Corporation Cephem derivatives and a method for producing the compounds and an antibacterialcomposition containing the compounds
IL140084A0 (en) 1998-06-05 2002-02-10 Astra Ab Oxazolidinone derivatives, process for their preparation and pharmaceutical compositions containing them
GB9812019D0 (en) 1998-06-05 1998-07-29 Zeneca Ltd Chemical compounds
EP1085846A2 (en) 1998-06-08 2001-03-28 Advanced Medicine, Inc. Multibinding inhibitors of microsomal triglyceride transferase protein
GB9821938D0 (en) 1998-10-09 1998-12-02 Zeneca Ltd Chemical compounds
GB9928568D0 (en) 1999-12-03 2000-02-02 Zeneca Ltd Chemical compounds
GB9928499D0 (en) 1999-12-03 2000-02-02 Zeneca Ltd Chemical processes and intermediates
GB0009803D0 (en) 2000-04-25 2000-06-07 Astrazeneca Ab Chemical compounds
BR0111280A (pt) 2000-06-05 2003-06-10 Dong A Pharm Co Ltd Novos derivados de oxazolidinona e um processo para a preparação dos mesmos
DE10034624A1 (de) 2000-07-17 2002-01-31 Bayer Ag Aryl-substituierte Thienyl-1,3-oxazolidin-2-one als Cytokin-Inhibitoren
DE10034625A1 (de) 2000-07-17 2002-01-31 Bayer Ag Heterocyclisch substituierte Thienyl-Phenyl-Oxazolidinone
US20020115669A1 (en) * 2000-08-31 2002-08-22 Wiedeman Paul E. Oxazolidinone chemotherapeutic agents
YU52403A (sh) 2000-12-26 2006-03-03 Dr.Reddy's Research Foundation Heterociklična jedinjenja koja imaju antibakterijsko dejstvo, postupak za njihovo dobijanje i farmaceutske smeše koje ih sadrže
GB0108794D0 (en) 2001-04-07 2001-05-30 Astrazeneca Ab Chemical compound
ES2268011T3 (es) 2001-04-07 2007-03-16 Astrazeneca Ab Oxazolidinonas que contienen un grupo sulfonimida como antibioticos.
GB0108764D0 (en) 2001-04-07 2001-05-30 Astrazeneca Ab Chemical compounds
GB0108793D0 (en) 2001-04-07 2001-05-30 Astrazeneca Ab Chemical compounds
GB0113299D0 (en) 2001-06-01 2001-07-25 Astrazeneca Ab Chemical process & intermediates
GB0113298D0 (en) 2001-06-01 2001-07-25 Astrazeneca Ab Purification process and intermediates
GB0113297D0 (en) 2001-06-01 2001-07-25 Astrazeneca Ab Chemical Process
GB0113300D0 (en) 2001-06-01 2001-07-25 Astrazeneca Ab Purification process
EP1451164A2 (en) 2001-07-12 2004-09-01 PHARMACIA & UPJOHN COMPANY Amide derivatives having improved solubility
GB0118407D0 (en) 2001-07-27 2001-09-19 Cipla Ltd Oxazolidinone derivatives as antibacterial agents
WO2003031443A1 (en) 2001-10-04 2003-04-17 Morphochem Aktiengesellschaft für kombinatorische Chemie Dual actions antibiotics comprising a oxazoldinone and a quinolone or naphthyridinone moiety
WO2003031441A1 (en) 2001-10-04 2003-04-17 Morphochen Aktiengesellschaft Für Kombinatorische Chemie Multiple action compounds
JP2005512975A (ja) 2001-10-25 2005-05-12 アストラゼネカ アクチボラグ 抗菌薬として有用なイソキサゾリン誘導体
EP1446403B1 (en) 2001-10-25 2006-04-12 AstraZeneca AB Aryl substituted oxazolidinones with antibacterial activity
AU2003207340A1 (en) 2002-02-28 2003-09-09 Astrazeneca Ab 3-cyclyl-5-(nitrogen-containing 5-membered ring) methyl-oxazolidinone derivatives and their use as antibacterial agents
KR20040086465A (ko) 2002-02-28 2004-10-08 아스트라제네카 아베 화합물
JP2003335762A (ja) 2002-05-20 2003-11-28 Meiji Seika Kaisha Ltd 新規ビフェニル誘導体
TW200420573A (en) 2002-09-26 2004-10-16 Rib X Pharmaceuticals Inc Bifunctional heterocyclic compounds and methods of making and using same
BR0316688A (pt) * 2002-11-28 2005-10-18 Astrazeneca Ab Composto, prodroga de um composto, método de produzir um efeito antibacteriano em um animal de sangue quente, uso de um composto, composição farmacêutica, e, processo para a preparação de um composto

Also Published As

Publication number Publication date
HUP0401005A2 (hu) 2004-08-30
CA2459766A1 (en) 2003-03-20
JP2005507386A (ja) 2005-03-17
EP1427711A1 (en) 2004-06-16
KR20040044886A (ko) 2004-05-31
US7396847B2 (en) 2008-07-08
WO2003022824A1 (en) 2003-03-20
CN1639136A (zh) 2005-07-13
NO327010B1 (no) 2009-04-06
NZ531621A (en) 2005-06-24
IS7175A (is) 2004-03-10
SI1427711T1 (sl) 2005-12-31
RU2004111285A (ru) 2005-10-10
AR036778A1 (es) 2004-10-06
IL160739A0 (en) 2004-08-31
AU2002329393B2 (en) 2008-06-12
US20050107435A1 (en) 2005-05-19
PT1427711E (pt) 2005-11-30
HUP0401005A3 (en) 2007-11-28
EP1427711B1 (en) 2005-07-13
NO20041428L (no) 2004-06-08
BR0212458A (pt) 2004-10-19
DK1427711T3 (da) 2005-10-17
ES2244802T3 (es) 2005-12-16
PL369183A1 (en) 2005-04-18
ATE299502T1 (de) 2005-07-15
DE60205030T2 (de) 2006-04-20
MXPA04002303A (es) 2004-06-29
US20100137243A1 (en) 2010-06-03
HK1065789A1 (en) 2005-03-04
DE60205030D1 (de) 2005-08-18

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